iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044486

UUCD1 version

UUC-GoG-00184

Ensembl Protein ID

ENSGGOP00000004270.2

UniProt Accession

G3QNY8; G3QNY8_GORGO

Protein Name

Uncharacterized protein

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000004350.2	ENSGGOT00000004374.2	ENSGGOP00000004270.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-11	44.0	91	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           Htd v  l+f  s+  ++s+s D+t+k+W+
   Q: 91   HTDQVLHLSFshSGYQFASCSKDCTVKIWS 120
           9*********955588*************8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MDEGGTPLLP DSLVYQIFLS LGPADVLAAG LVCRQWQAVS RDEFLWREQF YRYYQVARDV 60
PRHPAAMSWY EEFQRLYDTV PCVEVQTLRE HTDQVLHLSF SHSGYQFASC SKDCTVKIWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCGCCTG GGCAGAATGT CACGATGGAC GAGGGCGGCA CGCCCCTGCT CCCCGACAGC 60
CTGGTCTACC AGATCTTCCT GAGCCTGGGC CCGGCCGACG TGCTGGCCGC CGGGCTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

ggo:101128872

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	90.53	0.00e+00	1010.00
IUUC-Apl-003274	Anas platyrhynchos	77.47	0.00e+00	780.00
IUUC-Aca-004626	Anolis carolinensis	59.68	5.00e-98	350.00
IUUC-Ame-011823	Astyanax mexicanus	61.08	7.00e-177	613.00
IUUC-Bta-012523	Bos taurus	90.27	0.00e+00	1027.00
IUUC-Cja-018729	Callithrix jacchus	95.42	0.00e+00	1109.00
IUUC-Cfa-020303	Canis familiaris	90.88	0.00e+00	1047.00
IUUC-Cpo-022134	Cavia porcellus	91.74	0.00e+00	1065.00
IUUC-Csa-023253	Chlorocebus sabaeus	98.06	0.00e+00	1155.00
IUUC-Cin-025742	Ciona intestinalis	34.68	2.00e-82	300.00
IUUC-Dre-027511	Danio rerio	68.28	0.00e+00	734.00
IUUC-Dno-029044	Dasypus novemcinctus	89.77	0.00e+00	1025.00
IUUC-Dor-030565	Dipodomys ordii	89.98	0.00e+00	1042.00
IUUC-Dme-031713	Drosophila melanogaster	40.79	1.00e-126	446.00
IUUC-Eca-033709	Equus caballus	91.37	0.00e+00	1036.00
IUUC-Eeu-035093	Erinaceus europaeus	95.58	1.00e-102	366.00
IUUC-Fca-035674	Felis catus	90.16	0.00e+00	1035.00
IUUC-Fal-037104	Ficedula albicollis	71.28	0.00e+00	824.00
IUUC-Gmo-039041	Gadus morhua	62.52	0.00e+00	649.00
IUUC-Gga-041230	Gallus gallus	75.21	0.00e+00	882.00
IUUC-Gac-042594	Gasterosteus aculeatus	61.51	0.00e+00	655.00
IUUC-Hsa-045701	Homo sapiens	99.29	0.00e+00	1139.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	90.54	0.00e+00	1068.00
IUUC-Kpa-049204	Komagataella pastoris	38.00	4.00e-06	46.60
IUUC-Lch-050058	Latimeria chalumnae	70.02	0.00e+00	827.00
IUUC-Loc-052525	Lepisosteus oculatus	71.35	0.00e+00	738.00
IUUC-Laf-054120	Loxodonta africana	88.20	0.00e+00	1025.00
IUUC-Mcc-054915	Macaca mulatta	97.70	0.00e+00	1124.00
IUUC-Meu-056715	Macropus eugenii	79.12	0.00e+00	925.00
IUUC-Mga-059831	Meleagris gallopavo	75.05	0.00e+00	786.00
IUUC-Mvi-060236	Microbotryum violaceum	34.62	2.00e-06	48.90
IUUC-Mmr-060655	Microcebus murinus	92.59	0.00e+00	1085.00
IUUC-Mdo-062641	Monodelphis domestica	83.39	0.00e+00	962.00
IUUC-Mmu-063471	Mus musculus	88.70	0.00e+00	1035.00
IUUC-Mpu-066586	Mustela putorius furo	90.53	0.00e+00	1028.00
IUUC-Nle-069429	Nomascus leucogenys	97.88	0.00e+00	1153.00
IUUC-Ont-071780	Oreochromis niloticus	66.90	0.00e+00	715.00
IUUC-Ola-086458	Oryzias latipes	66.17	0.00e+00	729.00
IUUC-Oga-088739	Otolemur garnettii	91.90	0.00e+00	1092.00
IUUC-Oar-089275	Ovis aries	93.02	1.00e-46	177.00
IUUC-Ptr-090716	Pan troglodytes	98.74	0.00e+00	946.00
IUUC-Pan-092182	Papio anubis	89.05	0.00e+00	994.00
IUUC-Psi-093449	Pelodiscus sinensis	75.85	0.00e+00	884.00
IUUC-Pma-094289	Petromyzon marinus	54.04	4.00e-175	607.00
IUUC-Pfo-096062	Poecilia formosa	66.61	0.00e+00	724.00
IUUC-Pab-098726	Pongo abelii	96.30	0.00e+00	1108.00
IUUC-Pca-100163	Procavia capensis	81.77	2.00e-91	329.00
IUUC-Pva-103051	Pteropus vampyrus	90.58	5.00e-148	517.00
IUUC-Rno-105707	Rattus norvegicus	89.49	0.00e+00	1039.00
IUUC-Sha-107074	Sarcophilus harrisii	83.46	0.00e+00	910.00
IUUC-Ssc-116020	Sus scrofa	88.73	0.00e+00	853.00
IUUC-Tgu-116683	Taeniopygia guttata	69.18	1.00e-99	355.00
IUUC-Tru-118143	Takifugu rubripes	66.03	0.00e+00	705.00
IUUC-Tni-120777	Tetraodon nigroviridis	65.98	0.00e+00	714.00
IUUC-Ttr-128439	Tursiops truncatus	89.93	0.00e+00	1026.00
IUUC-Xtr-132774	Xenopus tropicalis	56.76	6.00e-150	523.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence