iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066586

Ensembl Protein ID

ENSMPUP00000010876.1

UniProt Accession

M3YHR9; M3YHR9_MUSPF

Genbank Protein ID

ENSMPUP00000010876

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01042254

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010965.1	ENSMPUT00000011058.1	ENSMPUP00000010876.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-11	42.5	91	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWD 29
           H+d v  l+f  s+  ++s+s D+t+k+W+
   Q: 91   HADQVLHLSFshSGYQFASCSKDCTVKIWN 120
           99********955588*************9 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MDEGGTPLLP DSLIYQIFLS LGPADVLAAG LVCRQWQAVS RDEFLWREQF YRYYQVARDV 60
PRHPAATSWY EEFRRLYDTV PCVEVQTLRE HADQVLHLSF SHSGYQFASC SKDCTVKIWN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGG GGGGCACACC CCTGCTCCCT GACAGCCTCA TCTACCAGAT CTTCCTGAGC 60
TTGGGCCCAG CGGACGTACT GGCCGCCGGT CTGGTGTGCC GCCAGTGGCA GGCCGTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	95.24	0.00e+00	1056.00
IUUC-Apl-003274	Anas platyrhynchos	77.67	0.00e+00	771.00
IUUC-Aca-004626	Anolis carolinensis	61.41	4.00e-100	357.00
IUUC-Ame-011823	Astyanax mexicanus	60.87	3.00e-177	615.00
IUUC-Bta-012523	Bos taurus	91.39	0.00e+00	1021.00
IUUC-Cja-018729	Callithrix jacchus	90.38	0.00e+00	1030.00
IUUC-Cfa-020303	Canis familiaris	96.64	0.00e+00	1093.00
IUUC-Cpo-022134	Cavia porcellus	91.21	0.00e+00	1033.00
IUUC-Csa-023253	Chlorocebus sabaeus	91.05	0.00e+00	1054.00
IUUC-Cin-025742	Ciona intestinalis	33.62	3.00e-78	286.00
IUUC-Dre-027511	Danio rerio	68.36	0.00e+00	730.00
IUUC-Dno-029044	Dasypus novemcinctus	87.19	0.00e+00	997.00
IUUC-Dor-030565	Dipodomys ordii	89.47	0.00e+00	1010.00
IUUC-Dme-031713	Drosophila melanogaster	41.78	7.00e-126	444.00
IUUC-Eca-033709	Equus caballus	93.68	0.00e+00	1029.00
IUUC-Eeu-035093	Erinaceus europaeus	95.58	7.00e-103	367.00
IUUC-Fca-035674	Felis catus	95.06	0.00e+00	1067.00
IUUC-Fal-037104	Ficedula albicollis	74.51	0.00e+00	820.00
IUUC-Gmo-039041	Gadus morhua	61.99	0.00e+00	646.00
IUUC-Gga-041230	Gallus gallus	75.04	0.00e+00	865.00
IUUC-Gac-042594	Gasterosteus aculeatus	61.84	0.00e+00	656.00
IUUC-Ggo-044486	Gorilla gorilla	90.53	0.00e+00	1021.00
IUUC-Hsa-045701	Homo sapiens	90.18	0.00e+00	1019.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	91.24	0.00e+00	1045.00
IUUC-Kpa-049204	Komagataella pastoris	31.88	2.00e-06	47.40
IUUC-Lch-050058	Latimeria chalumnae	70.83	0.00e+00	828.00
IUUC-Loc-052525	Lepisosteus oculatus	70.00	0.00e+00	736.00
IUUC-Laf-054120	Loxodonta africana	88.44	0.00e+00	1010.00
IUUC-Mcc-054915	Macaca mulatta	90.70	0.00e+00	1026.00
IUUC-Meu-056715	Macropus eugenii	78.05	0.00e+00	905.00
IUUC-Mga-059831	Meleagris gallopavo	75.05	0.00e+00	771.00
IUUC-Mvi-060236	Microbotryum violaceum	37.18	1.00e-07	52.80
IUUC-Mmr-060655	Microcebus murinus	91.77	0.00e+00	1044.00
IUUC-Mdo-062641	Monodelphis domestica	83.39	0.00e+00	959.00
IUUC-Mmu-063471	Mus musculus	88.87	0.00e+00	1015.00
IUUC-Nle-069429	Nomascus leucogenys	90.70	0.00e+00	1050.00
IUUC-Ont-071780	Oreochromis niloticus	65.97	0.00e+00	708.00
IUUC-Ola-086458	Oryzias latipes	66.32	0.00e+00	720.00
IUUC-Oga-088739	Otolemur garnettii	90.03	0.00e+00	1039.00
IUUC-Oar-089275	Ovis aries	94.19	3.00e-47	179.00
IUUC-Ptr-090716	Pan troglodytes	88.33	0.00e+00	831.00
IUUC-Pan-092182	Papio anubis	82.11	0.00e+00	901.00
IUUC-Psi-093449	Pelodiscus sinensis	75.51	0.00e+00	870.00
IUUC-Pma-094289	Petromyzon marinus	54.04	3.00e-173	601.00
IUUC-Pfo-096062	Poecilia formosa	66.50	0.00e+00	720.00
IUUC-Pab-098726	Pongo abelii	89.65	0.00e+00	1024.00
IUUC-Pca-100163	Procavia capensis	84.57	8.00e-92	330.00
IUUC-Pva-103051	Pteropus vampyrus	93.70	5.00e-148	517.00
IUUC-Rno-105707	Rattus norvegicus	88.62	0.00e+00	1022.00
IUUC-Sha-107074	Sarcophilus harrisii	84.19	0.00e+00	911.00
IUUC-Ssc-116020	Sus scrofa	90.39	0.00e+00	854.00
IUUC-Tgu-116683	Taeniopygia guttata	70.25	7.00e-98	350.00
IUUC-Tru-118143	Takifugu rubripes	65.18	0.00e+00	702.00
IUUC-Tni-120777	Tetraodon nigroviridis	66.26	0.00e+00	713.00
IUUC-Ttr-128439	Tursiops truncatus	90.70	0.00e+00	1016.00
IUUC-Xtr-132774	Xenopus tropicalis	58.42	3.00e-148	518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence