iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106662

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01034874

Gene Name

WDR59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000011756.1	ENSSHAT00000013861.1	ENSSHAP00000013747.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.80e-18	63.9	175	209

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d  ++l+++s D+++k WD+r+ 
   Q: 175  HLSKIHGLDWhPDseHILATSSQDNSVKFWDYRQP 209
           99*********6665778*************9876 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

QATAMSVDCL GQHAVLSGRR FLYIVNLDAP SEGHRKISRQ SKWDIGAVQW NPHDNYAHYF 60
AASSNQRVDL YKWKDGSGEV GTALQGHTRV ISLSDLDWAV FEPDLLVTSS VDTYIYIWDI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCAACTG CAATGTCTGT AGATTGTCTT GGGCAGCATG CAGTGCTTTC TGGGTAAGTG 60
AGCTCCAAAG TTCTCTTGTT GTATGATTTT TGGGAACAAG AAGTTTCTGA TCAAGTGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	94.79	0.00e+00	1841.00
IUUC-Apl-004021	Anas platyrhynchos	89.38	0.00e+00	1700.00
IUUC-Aca-004977	Anolis carolinensis	85.28	0.00e+00	1691.00
IUUC-Ago-007961	Ashbya gossypii	29.32	2.00e-54	207.00
IUUC-Acl-008161	Aspergillus clavatus	29.04	4.00e-55	210.00
IUUC-Afl-008686	Aspergillus flavus	28.62	3.00e-57	217.00
IUUC-Afu-008932	Aspergillus fumigatus	28.79	7.00e-56	213.00
IUUC-Ani-009493	Aspergillus nidulans	28.34	5.00e-58	220.00
IUUC-Ang-009876	Aspergillus niger	28.52	5.00e-57	216.00
IUUC-Aor-009926	Aspergillus oryzae	28.62	3.00e-57	217.00
IUUC-Ate-010274	Aspergillus terreus	27.47	1.00e-53	205.00
IUUC-Ame-011297	Astyanax mexicanus	71.11	0.00e+00	1413.00
IUUC-Bgr-012173	Blumeria graminis	31.46	1.00e-42	168.00
IUUC-Bta-013261	Bos taurus	95.52	0.00e+00	1863.00
IUUC-Bci-013971	Botrytis cinerea	33.86	9.00e-45	176.00
IUUC-Cja-019167	Callithrix jacchus	93.95	0.00e+00	1830.00
IUUC-Cfa-020287	Canis familiaris	94.89	0.00e+00	1841.00
IUUC-Cpo-022510	Cavia porcellus	92.08	0.00e+00	1769.00
IUUC-Csa-023474	Chlorocebus sabaeus	93.25	0.00e+00	1860.00
IUUC-Cho-024634	Choloepus hoffmanni	93.87	0.00e+00	731.00
IUUC-Cin-025642	Ciona intestinalis	31.99	3.00e-131	462.00
IUUC-Csv-025848	Ciona savignyi	44.23	8.00e-54	202.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	32.59	3.00e-43	171.00
IUUC-Cne-027088	Cryptococcus neoformans	32.73	2.00e-43	171.00
IUUC-Dre-028753	Danio rerio	71.96	0.00e+00	1383.00
IUUC-Dno-029733	Dasypus novemcinctus	93.96	0.00e+00	1826.00
IUUC-Dor-030781	Dipodomys ordii	95.69	0.00e+00	967.00
IUUC-Dme-031803	Drosophila melanogaster	33.88	1.00e-144	507.00
IUUC-Ete-032622	Echinops telfairi	87.04	0.00e+00	1631.00
IUUC-Eca-033344	Equus caballus	95.10	0.00e+00	1838.00
IUUC-Eeu-034523	Erinaceus europaeus	84.45	0.00e+00	1608.00
IUUC-Fca-035650	Felis catus	95.31	0.00e+00	1857.00
IUUC-Fal-037404	Ficedula albicollis	88.94	0.00e+00	1734.00
IUUC-Fox-037955	Fusarium oxysporum	33.93	3.00e-42	167.00
IUUC-Fso-038289	Fusarium solani	33.54	2.00e-45	177.00
IUUC-Gmo-038547	Gadus morhua	68.57	0.00e+00	1363.00
IUUC-Ggr-039858	Gaeumannomyces graminis	36.20	9.00e-42	166.00
IUUC-Gga-041030	Gallus gallus	89.56	0.00e+00	1721.00
IUUC-Gac-042581	Gasterosteus aculeatus	71.24	0.00e+00	1418.00
IUUC-Ggo-044641	Gorilla gorilla	95.10	0.00e+00	1855.00
IUUC-Hsa-046134	Homo sapiens	95.31	0.00e+00	1857.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	94.05	0.00e+00	725.00
IUUC-Kpa-049091	Komagataella pastoris	32.20	2.00e-42	167.00
IUUC-Lch-050288	Latimeria chalumnae	76.14	0.00e+00	1457.00
IUUC-Loc-052802	Lepisosteus oculatus	74.44	0.00e+00	1475.00
IUUC-Lma-053296	Leptosphaeria maculans	32.59	2.00e-45	178.00
IUUC-Laf-053997	Loxodonta africana	93.56	0.00e+00	1878.00
IUUC-Mcc-055855	Macaca mulatta	95.10	0.00e+00	1839.00
IUUC-Meu-056898	Macropus eugenii	98.48	0.00e+00	758.00
IUUC-Mor-056913	Magnaporthe oryzae	35.44	6.00e-42	166.00
IUUC-Mpo-057612	Magnaporthe poae	36.92	7.00e-43	169.00
IUUC-Mla-059097	Melampsora laricipopulina	30.79	3.00e-46	180.00
IUUC-Mga-059218	Meleagris gallopavo	89.35	0.00e+00	1715.00
IUUC-Mvi-060251	Microbotryum violaceum	31.58	7.00e-45	176.00
IUUC-Mmr-061093	Microcebus murinus	91.75	0.00e+00	1781.00
IUUC-Mdo-062757	Monodelphis domestica	95.33	0.00e+00	1867.00
IUUC-Mmu-063839	Mus musculus	92.43	0.00e+00	1853.00
IUUC-Mpu-065977	Mustela putorius furo	95.10	0.00e+00	1849.00
IUUC-Mlu-067460	Myotis lucifugus	93.16	0.00e+00	1838.00
IUUC-Nfi-068250	Neosartorya fischeri	28.49	7.00e-56	213.00
IUUC-Ncr-068710	Neurospora crassa	33.44	7.00e-44	173.00
IUUC-Nle-070011	Nomascus leucogenys	95.10	0.00e+00	1850.00
IUUC-Opr-070731	Ochotona princeps	87.49	0.00e+00	1665.00
IUUC-Ont-072165	Oreochromis niloticus	71.38	0.00e+00	1399.00
IUUC-Oan-072887	Ornithorhynchus anatinus	93.76	0.00e+00	1884.00
IUUC-Ocu-073926	Oryctolagus cuniculus	92.57	0.00e+00	1683.00
IUUC-Ola-087111	Oryzias latipes	67.31	0.00e+00	1330.00
IUUC-Oga-088850	Otolemur garnettii	94.99	0.00e+00	1846.00
IUUC-Oar-090291	Ovis aries	95.20	0.00e+00	1855.00
IUUC-Ptr-091044	Pan troglodytes	94.89	0.00e+00	1842.00
IUUC-Pan-092374	Papio anubis	93.05	0.00e+00	1854.00
IUUC-Psi-093170	Pelodiscus sinensis	59.05	0.00e+00	1011.00
IUUC-Pma-094544	Petromyzon marinus	66.89	3.00e-170	591.00
IUUC-Pno-095068	Phaeosphaeria nodorum	30.58	2.00e-41	164.00
IUUC-Pfo-096480	Poecilia formosa	69.08	0.00e+00	1347.00
IUUC-Pab-098134	Pongo abelii	93.74	0.00e+00	1813.00
IUUC-Pca-100763	Procavia capensis	72.67	0.00e+00	941.00
IUUC-Pva-102544	Pteropus vampyrus	94.16	0.00e+00	1845.00
IUUC-Pgr-103257	Puccinia graminis	32.72	7.00e-49	189.00
IUUC-Ptt-103942	Puccinia triticina	32.05	6.00e-45	176.00
IUUC-Pte-104065	Pyrenophora teres	31.88	7.00e-43	170.00
IUUC-Rno-105468	Rattus norvegicus	90.29	0.00e+00	1677.00
IUUC-Sce-106356	Saccharomyces cerevisiae	28.57	1.00e-54	208.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	27.82	5.00e-70	259.00
IUUC-Spo-108265	Schizosaccharomyces pombe	24.88	8.00e-69	255.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	34.14	3.00e-44	174.00
IUUC-Sar-113525	Sorex araneus	91.85	0.00e+00	1055.00
IUUC-Sre-115163	Sporisorium reilianum	37.15	8.00e-40	159.00
IUUC-Ssc-115381	Sus scrofa	94.66	0.00e+00	1031.00
IUUC-Tgu-116525	Taeniopygia guttata	85.30	0.00e+00	1635.00
IUUC-Tru-118432	Takifugu rubripes	69.64	0.00e+00	1392.00
IUUC-Tsy-119306	Tarsius syrichta	79.43	0.00e+00	1174.00
IUUC-Tni-120757	Tetraodon nigroviridis	68.80	0.00e+00	1349.00
IUUC-Tre-122187	Trichoderma reesei	35.13	1.00e-46	182.00
IUUC-Tvi-122367	Trichoderma virens	35.44	3.00e-46	181.00
IUUC-Tme-126986	Tuber melanosporum	25.63	6.00e-58	219.00
IUUC-Tbe-127800	Tupaia belangeri	84.61	0.00e+00	1237.00
IUUC-Ttr-129154	Tursiops truncatus	86.95	0.00e+00	1664.00
IUUC-Uma-129366	Ustilago maydis	36.08	7.00e-39	156.00
IUUC-Vda-129827	Verticillium dahliae	33.96	4.00e-46	180.00
IUUC-Vpa-130493	Vicugna pacos	95.20	0.00e+00	1836.00
IUUC-Xtr-131941	Xenopus tropicalis	81.65	0.00e+00	1573.00
IUUC-Xma-133903	Xiphophorus maculatus	70.46	0.00e+00	1384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence