iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000009845.3	ENSMMUT00000013753.3	ENSMMUP00000012887.3
ENSMMUG00000009845.3	ENSMMUT00000039462.2	ENSMMUP00000032550.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.00e-94	316.4	127	762

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle..........kkkeklneenp.........kepkgellkslqklfeelwkskkkavspr 71
           Gl+N+gNtC+mN++LQcLsn++ ++e+l            +         p          + +ge++++l++l+++lw+ + +    r
   Q: 127  GLRNHGNTCFMNATLQCLSNTELFAEYLALgqyragrpepS---------PdpeqpagrgAQGQGEVTEQLAHLVRALWTLEYTPQHSR 206
           9***************************9954444333330.........133334444456666************************ PP
   S: 72   ellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecd 160
           +++++++k a +++g++q+DaqEfl +lld+++e+l++  + +++ +   +  + +d+ +e +    ++++++lFq q++s+++c++c+
   Q: 207  DFKTIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLNH--SVKQSGQPPLKPPSETDMMPEGPFPVCSTFVQELFQAQYRSSLTCPHCQ 293
           ************************************44..5555555555556677888999999999********************* PP
   S: 161  nvssreepfldlslpvpgkeetkke................................................................ 185
           ++s++++pfl +slp+p  +++ ++                                                                
   Q: 294  KQSNTFDPFLCISLPIPLPHTR-PLyvtvvyqgkcshcmrigvavplsgtvarlreavsmetkiptdqivltemyydgfhrsfcdtddl 381
           *****************87755.34689************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 382  etvhesdcifafetpeifrpegilsqrgihlnnnlnhlkfgldyhrlssptqtaakqgkmdsstsragsdkivllvcnractgqqgkrf 470
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 471  glpfvlhlektiawdllqkeilekmkyflrptaciqvcpfslrvvsvvgityllpqeeqplchptveralkscgpggtahvklvvewdk 559
           ***************************************************************************************** PP
   S: 186  ..................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfs 240
                                             +l++c++ +tkee+l  ++++ c++ck++q+ + +l+l++lP+vLi+hLkRf  +
   Q: 560  etrdflfantedeyipdaesvrlqrerhhqpqtcTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRF--R 646
           **************************************************************************************..9 PP
   S: 241  eeqksrekinkkvefple.Ldlspfctspeekqke...................kkkYeLiavvvHsGslssGHYvayvknekgk.Wll 308
           +e+++r k+++ v+fpl+ Ld++p+++++++++ +                   +++Y+L+av++H+G++++GHY+ay+kn+ ++ W++
   Q: 647  QEGDRRMKLQNMVKFPLTgLDMTPHVVKRSQSSWSlpshwspwrrpyglgrdpeDYIYDLYAVCNHHGTMQGGHYTAYCKNSVDGlWYC 735
           9**************************977666559999999999999999999***************************87777*** PP
   S: 309  fdDskVtevkeeevleetgstaYvlfYkrr 338
           fdDs V++++e+ev++   +taY+lfY+rr
   Q: 736  FDDSDVQQLSEDEVCT---QTAYILFYQRR 762
           ****************...*********96 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSKVTGPGRG RRRRRAGRRS APSASGYSGA AALAAAPGPG ASGPAAPSSP SSPSSARSVG 60
SFMSRVLKTL STLSHLSSEG AAPDRGGLRS CFPPGPAAAP TPPPCPPPPA SPAPPACAAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAAGG TAACGGGCCC GGGTCGCGGC CGCCGGCGGC GGCGGGCGGG AAGGAGAAGC 60
GCTCCTTCAG CAAGCGGCTA TTCCGGAGCG GCCGCGCTGG CGGCGGCGCC GGGGCCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mcc:699540

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001207	Ailuropoda melanoleuca	92.76	0.00e+00	1969.00
IUUC-Apl-003186	Anas platyrhynchos	77.05	0.00e+00	1442.00
IUUC-Aca-004949	Anolis carolinensis	69.02	0.00e+00	1400.00
IUUC-Ame-010968	Astyanax mexicanus	66.63	0.00e+00	1108.00
IUUC-Bta-013271	Bos taurus	93.37	0.00e+00	1610.00
IUUC-Cja-019663	Callithrix jacchus	94.59	0.00e+00	1793.00
IUUC-Cfa-021258	Canis familiaris	92.46	0.00e+00	1975.00
IUUC-Csa-024188	Chlorocebus sabaeus	99.22	0.00e+00	1660.00
IUUC-Cho-024813	Choloepus hoffmanni	85.60	0.00e+00	1574.00
IUUC-Csv-026086	Ciona savignyi	38.18	2.00e-133	469.00
IUUC-Dre-027372	Danio rerio	70.38	0.00e+00	1023.00
IUUC-Dno-029964	Dasypus novemcinctus	87.17	0.00e+00	1798.00
IUUC-Dor-030448	Dipodomys ordii	84.13	0.00e+00	1170.00
IUUC-Ete-032975	Echinops telfairi	75.42	0.00e+00	1454.00
IUUC-Eca-034030	Equus caballus	93.04	0.00e+00	1912.00
IUUC-Eeu-034629	Erinaceus europaeus	75.30	0.00e+00	1172.00
IUUC-Fca-035788	Felis catus	94.80	0.00e+00	1600.00
IUUC-Fal-036874	Ficedula albicollis	84.10	0.00e+00	1283.00
IUUC-Gmo-039479	Gadus morhua	57.38	0.00e+00	1194.00
IUUC-Gga-041092	Gallus gallus	74.29	0.00e+00	1555.00
IUUC-Gac-041609	Gasterosteus aculeatus	71.03	0.00e+00	1136.00
IUUC-Ggo-044782	Gorilla gorilla	95.96	0.00e+00	813.00
IUUC-Hsa-046805	Homo sapiens	97.91	0.00e+00	2055.00
IUUC-Itr-048158	Ictidomys tridecemlineatus	92.74	0.00e+00	1770.00
IUUC-Lch-050332	Latimeria chalumnae	64.84	0.00e+00	1311.00
IUUC-Loc-051953	Lepisosteus oculatus	61.76	0.00e+00	1264.00
IUUC-Meu-056822	Macropus eugenii	77.26	0.00e+00	1465.00
IUUC-Mga-060115	Meleagris gallopavo	74.72	0.00e+00	1421.00
IUUC-Mmr-061150	Microcebus murinus	94.96	0.00e+00	1928.00
IUUC-Mdo-062700	Monodelphis domestica	81.11	0.00e+00	1811.00
IUUC-Mmu-063512	Mus musculus	90.56	0.00e+00	1860.00
IUUC-Mpu-066059	Mustela putorius furo	90.75	0.00e+00	1718.00
IUUC-Mlu-067870	Myotis lucifugus	86.43	0.00e+00	1724.00
IUUC-Nle-069898	Nomascus leucogenys	97.96	0.00e+00	2001.00
IUUC-Opr-070338	Ochotona princeps	80.46	0.00e+00	878.00
IUUC-Oan-073175	Ornithorhynchus anatinus	86.26	0.00e+00	1355.00
IUUC-Ola-087303	Oryzias latipes	69.76	0.00e+00	1099.00
IUUC-Oga-089021	Otolemur garnettii	94.22	0.00e+00	1917.00
IUUC-Oar-090016	Ovis aries	95.02	0.00e+00	1617.00
IUUC-Ptr-090864	Pan troglodytes	98.06	0.00e+00	2060.00
IUUC-Pan-092370	Papio anubis	99.84	0.00e+00	2004.00
IUUC-Psi-093881	Pelodiscus sinensis	76.16	0.00e+00	1447.00
IUUC-Pfo-097427	Poecilia formosa	69.84	0.00e+00	1115.00
IUUC-Pab-098104	Pongo abelii	95.12	0.00e+00	1959.00
IUUC-Pca-100640	Procavia capensis	97.27	1.00e-128	454.00
IUUC-Pva-102287	Pteropus vampyrus	82.59	0.00e+00	1521.00
IUUC-Rno-106033	Rattus norvegicus	90.89	0.00e+00	1807.00
IUUC-Sha-107041	Sarcophilus harrisii	83.93	0.00e+00	1643.00
IUUC-Ssc-116412	Sus scrofa	84.58	0.00e+00	751.00
IUUC-Tgu-116889	Taeniopygia guttata	76.27	0.00e+00	1445.00
IUUC-Tru-118340	Takifugu rubripes	70.21	0.00e+00	1113.00
IUUC-Tsy-118887	Tarsius syrichta	89.55	0.00e+00	1736.00
IUUC-Tni-120463	Tetraodon nigroviridis	70.32	0.00e+00	1116.00
IUUC-Tbe-127491	Tupaia belangeri	93.77	2.00e-135	477.00
IUUC-Ttr-128210	Tursiops truncatus	88.61	0.00e+00	1542.00
IUUC-Vpa-130222	Vicugna pacos	82.00	0.00e+00	805.00
IUUC-Xtr-132509	Xenopus tropicalis	63.67	0.00e+00	1330.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence