iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107631

Ensembl Protein ID

ENSSHAP00000005569.1

UniProt Accession

G3VQW4; G3VQW4_SARHA

Genbank Protein ID

ENSSHAP00000005569

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01143184

Gene Name

TRIM28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000004865.1	ENSSHAT00000005623.1	ENSSHAP00000005569.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.10e-09	36.3	367	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           +vC vC+++g+    lv+C++C+ +fH +C+ ++  +e+p++e w C+ C++
   Q: 367  TVCRVCQKPGD----LVMCSQCEFCFHLECHLPA-LQEVPGEE-WSCSLCQE 412
           69*********....*******************.*******8.******75 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

RYQFLEDAVR NQRKLLASLV KRLGDKHATL QKNTKEVRTS IRQVTDVQKR VQVDVKMAIL 60
QIMKELNKRG RVLVNDAQKV TEGQQERLER QHWTMTKIQR HQEHILRFAS WALESDNNTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTACCAGT TCCTGGAGGA TGCCGTCAGA AACCAGAGGA AGCTCCTGGC CTCCTTGGTC 60
AAGCGCCTGG GGGACAAGCA CGCCACCCTG CAGAAGAACA CCAAGGAAGT GCGCACCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00502--BBC
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005719--C:nuclear euchromatin
GO:0005720--C:nuclear heterochromatin
GO:0005654--C:nucleoplasm
GO:0090575--C:RNA polymerase II transcription factor complex
GO:1990841--F:promoter-specific chromatin binding
GO:0004672--F:protein kinase activity
GO:0003723--F:RNA binding
GO:0001105--F:RNA polymerase II transcription coactivator activity
GO:0043565--F:sequence-specific DNA binding
GO:0003714--F:transcription corepressor activity
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060028--P:convergent extension involved in axis elongation
GO:0043045--P:DNA methylation involved in embryo development
GO:0006281--P:DNA repair
GO:0007566--P:embryo implantation
GO:0060669--P:embryonic placenta morphogenesis
GO:0001837--P:epithelial to mesenchymal transition
GO:0045087--P:innate immune response
GO:1901536--P:negative regulation of DNA demethylation
GO:0045869--P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:1902187--P:negative regulation of viral release from host cell
GO:0043388--P:positive regulation of DNA binding
GO:0045739--P:positive regulation of DNA repair
GO:0090309--P:positive regulation of methylation-dependent chromatin silencing
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0046777--P:protein autophosphorylation
GO:0051259--P:protein oligomerization
GO:0016925--P:protein sumoylation
GO:0007265--P:Ras protein signal transduction
GO:2000653--P:regulation of genetic imprinting

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dor-030744	Dipodomys ordii	75.21	0.00e+00	829.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence