iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000010831.3	ENSFCAT00000027195.1	ENSFCAP00000022754.1
ENSFCAG00000010831.3	ENSFCAT00000010834.3	ENSFCAP00000010062.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-47	162.1	410	736

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 410  GLINKGNWCYINATLQALVACPPMYHLMKF-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 496
           9***************************99.333333.334799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk...............eknkpkeeeeeedkselsde............... 129
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+ +               +                                  
   Q: 497  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkkllspnnqkltvsN------------------Gprspsvhedeqdepg 567
           *9999999999966599********************334445554433444330..................1233334445556666 PP
   S: 130  ................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeeleg 202
                           +  ++ +  +++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g
   Q: 568  egsedeweqvgprsktSVTRQAEFVQTPITGIFGGHIR-SVVYQQSSRESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG 652
           67777788888876666666666677***********9.688999999*******************99...****************8 PP
   S: 203  enkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG 288
               y++k k+++e +++++l+klP+vL+lhLkRf ++++++++ k+ k+ve+p  L++s+ + sp  k+k+   +++Y+L+a +  +G
   Q: 653  ----YTTKTKQEVEISRRVTLEKLPPVLVLHLKRFVYEKTGGCQ-KLVKSVEYPVDLEISKELLSPGVKNKNfkcHRTYRLFAALPCHG 736
           ....99999****************************9998886.****************999988777777779*******987777 PP

Organism

Felis catus

Protein Sequence
(Fasta)

QYIFGDFSPD EFNQFFVTPR SSVELPPYNG TVLCGTQAPD ELPDGQEYQR IEFGVNEVIE 60
PNDTLPRTPN YSISSTLNPQ APEFILSCTT SKKIPDDVDK EAAYSSVDCQ YPGSALALDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTTTTTTT TTTTCCAGTA TATTTTTGGA GACTTTAGCC CTGATGAATT CAATCAGTTC 60
TTTGTGACTC CTCGCTCTTC AGTTGAGGTA AGACGAAACA GTGTTTTGTT TGAATATGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	28.57	1.00e-33	138.00
IUUC-Aml-001584	Ailuropoda melanoleuca	91.35	0.00e+00	1251.00
IUUC-Atr-002927	Amborella trichopoda	35.12	3.00e-49	189.00
IUUC-Apl-003988	Anas platyrhynchos	76.99	0.00e+00	1007.00
IUUC-Aca-004461	Anolis carolinensis	84.75	3.00e-128	451.00
IUUC-Aly-006038	Arabidopsis lyrata	34.52	2.00e-44	173.00
IUUC-Ath-007328	Arabidopsis thaliana	34.52	6.00e-44	172.00
IUUC-Ago-007717	Ashbya gossypii	27.76	1.00e-30	128.00
IUUC-Acl-008188	Aspergillus clavatus	34.30	2.00e-51	197.00
IUUC-Afl-008456	Aspergillus flavus	37.21	5.00e-38	151.00
IUUC-Afu-009067	Aspergillus fumigatus	34.92	6.00e-54	206.00
IUUC-Ani-009483	Aspergillus nidulans	31.99	6.00e-50	192.00
IUUC-Ang-009639	Aspergillus niger	34.77	1.00e-47	185.00
IUUC-Aor-010040	Aspergillus oryzae	34.59	1.00e-49	191.00
IUUC-Ate-010310	Aspergillus terreus	33.51	8.00e-50	192.00
IUUC-Ame-011012	Astyanax mexicanus	75.94	1.00e-161	563.00
IUUC-Bgr-012311	Blumeria graminis	32.36	3.00e-33	137.00
IUUC-Bta-013299	Bos taurus	87.47	0.00e+00	1184.00
IUUC-Bci-013783	Botrytis cinerea	36.71	2.00e-47	184.00
IUUC-Bdi-015039	Brachypodium distachyon	30.90	4.00e-39	156.00
IUUC-Bol-015806	Brassica oleracea	36.80	2.00e-51	196.00
IUUC-Bra-017076	Brassica rapa	36.50	4.00e-51	195.00
IUUC-Cja-018715	Callithrix jacchus	85.68	0.00e+00	1170.00
IUUC-Cfa-020194	Canis familiaris	92.84	0.00e+00	1268.00
IUUC-Cpo-022272	Cavia porcellus	71.60	0.00e+00	892.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	30.49	4.00e-24	106.00
IUUC-Csa-023310	Chlorocebus sabaeus	86.49	0.00e+00	1186.00
IUUC-Cho-024966	Choloepus hoffmanni	76.98	0.00e+00	894.00
IUUC-Cin-025616	Ciona intestinalis	43.87	2.00e-78	287.00
IUUC-Csv-026043	Ciona savignyi	42.67	1.00e-73	270.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	32.46	4.00e-33	136.00
IUUC-Cne-026962	Cryptococcus neoformans	33.89	2.00e-43	171.00
IUUC-Cme-027113	Cyanidioschyzon merolae	31.07	6.00e-30	125.00
IUUC-Dre-028072	Danio rerio	75.12	7.00e-171	594.00
IUUC-Dno-029489	Dasypus novemcinctus	86.23	0.00e+00	1191.00
IUUC-Dor-031068	Dipodomys ordii	71.51	1.00e-133	470.00
IUUC-Dse-031553	Dothistroma septosporum	35.09	8.00e-44	172.00
IUUC-Dme-031759	Drosophila melanogaster	39.30	2.00e-62	234.00
IUUC-Ete-032549	Echinops telfairi	77.93	0.00e+00	838.00
IUUC-Eca-033380	Equus caballus	86.64	0.00e+00	1212.00
IUUC-Eeu-034818	Erinaceus europaeus	83.67	0.00e+00	1146.00
IUUC-Fal-036627	Ficedula albicollis	74.66	0.00e+00	968.00
IUUC-Fox-037904	Fusarium oxysporum	33.90	2.00e-45	177.00
IUUC-Fso-038170	Fusarium solani	31.21	1.00e-43	171.00
IUUC-Gmo-039499	Gadus morhua	68.66	6.00e-153	534.00
IUUC-Ggr-040042	Gaeumannomyces graminis	34.09	3.00e-50	194.00
IUUC-Gga-040571	Gallus gallus	76.95	0.00e+00	1008.00
IUUC-Gac-041345	Gasterosteus aculeatus	75.39	1.00e-154	540.00
IUUC-Gma-044407	Glycine max	35.01	1.00e-48	187.00
IUUC-Ggo-044652	Gorilla gorilla	86.49	0.00e+00	1200.00
IUUC-Hsa-045864	Homo sapiens	86.76	0.00e+00	1206.00
IUUC-Hvu-047071	Hordeum vulgare	31.61	6.00e-42	164.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	87.57	0.00e+00	872.00
IUUC-Kpa-049132	Komagataella pastoris	32.14	3.00e-35	143.00
IUUC-Lch-050040	Latimeria chalumnae	66.81	0.00e+00	773.00
IUUC-Loc-052449	Lepisosteus oculatus	75.36	2.00e-166	579.00
IUUC-Lma-053248	Leptosphaeria maculans	34.76	3.00e-47	183.00
IUUC-Laf-054121	Loxodonta africana	86.10	0.00e+00	1213.00
IUUC-Mcc-055514	Macaca mulatta	86.62	0.00e+00	1191.00
IUUC-Meu-056873	Macropus eugenii	72.21	0.00e+00	808.00
IUUC-Mor-057243	Magnaporthe oryzae	33.05	5.00e-47	183.00
IUUC-Mpo-057439	Magnaporthe poae	34.94	9.00e-51	195.00
IUUC-Mtr-058457	Medicago truncatula	34.42	2.00e-47	183.00
IUUC-Mla-058929	Melampsora laricipopulina	30.37	6.00e-45	175.00
IUUC-Mga-060157	Meleagris gallopavo	75.33	0.00e+00	1014.00
IUUC-Mvi-060442	Microbotryum violaceum	33.78	2.00e-41	164.00
IUUC-Mmr-061062	Microcebus murinus	86.33	0.00e+00	1200.00
IUUC-Mdo-062798	Monodelphis domestica	79.22	0.00e+00	1058.00
IUUC-Mmu-064050	Mus musculus	79.22	0.00e+00	1088.00
IUUC-Mac-065202	Musa acuminata	33.82	5.00e-43	168.00
IUUC-Mpu-066554	Mustela putorius furo	90.82	0.00e+00	1229.00
IUUC-Mlu-068003	Myotis lucifugus	87.30	0.00e+00	1195.00
IUUC-Nfi-068612	Neosartorya fischeri	33.33	2.00e-52	200.00
IUUC-Ncr-068878	Neurospora crassa	32.88	3.00e-43	170.00
IUUC-Nle-069661	Nomascus leucogenys	86.89	0.00e+00	1193.00
IUUC-Opr-070944	Ochotona princeps	79.18	2.00e-158	552.00
IUUC-Ont-071266	Oreochromis niloticus	75.84	2.00e-160	559.00
IUUC-Oan-073442	Ornithorhynchus anatinus	77.51	0.00e+00	981.00
IUUC-Ocu-073788	Oryctolagus cuniculus	78.03	0.00e+00	1008.00
IUUC-Oba-075085	Oryza barthii	33.68	1.00e-29	122.00
IUUC-Obr-076663	Oryza brachyantha	31.91	5.00e-39	155.00
IUUC-Ogl-076937	Oryza glaberrima	28.93	2.00e-38	153.00
IUUC-Ogu-078909	Oryza glumaepatula	29.47	4.00e-38	152.00
IUUC-Oin-079617	Oryza indica	30.00	3.00e-40	159.00
IUUC-Olo-081043	Oryza longistaminata	23.92	7.00e-19	88.60
IUUC-Oni-082914	Oryza nivara	29.47	3.00e-38	153.00
IUUC-Oru-084878	Oryza rufipogon	29.47	3.00e-38	153.00
IUUC-Osa-085822	Oryza sativa	30.00	1.00e-40	160.00
IUUC-Ola-086931	Oryzias latipes	55.28	0.00e+00	643.00
IUUC-Oga-088443	Otolemur garnettii	85.81	0.00e+00	1199.00
IUUC-Oar-089325	Ovis aries	84.32	0.00e+00	1092.00
IUUC-Ptr-091584	Pan troglodytes	84.36	0.00e+00	1110.00
IUUC-Pan-092551	Papio anubis	84.59	0.00e+00	1153.00
IUUC-Psi-093366	Pelodiscus sinensis	73.67	0.00e+00	661.00
IUUC-Pno-095136	Phaeosphaeria nodorum	34.69	4.00e-42	166.00
IUUC-Ppa-095574	Physcomitrella patens	34.02	4.00e-48	186.00
IUUC-Pfo-097462	Poecilia formosa	73.19	6.00e-160	557.00
IUUC-Pab-098547	Pongo abelii	87.03	0.00e+00	1194.00
IUUC-Pop-099529	Populus trichocarpa	36.01	1.00e-50	194.00
IUUC-Pca-101066	Procavia capensis	75.95	0.00e+00	1006.00
IUUC-Ppe-102110	Prunus persica	35.59	5.00e-49	188.00
IUUC-Pva-103015	Pteropus vampyrus	82.59	0.00e+00	1114.00
IUUC-Ptt-103998	Puccinia triticina	31.91	6.00e-42	165.00
IUUC-Pte-104417	Pyrenophora teres	32.63	3.00e-46	180.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	33.42	3.00e-46	180.00
IUUC-Rno-105533	Rattus norvegicus	79.92	0.00e+00	1078.00
IUUC-Sce-106160	Saccharomyces cerevisiae	25.36	4.00e-23	103.00
IUUC-Sha-106590	Sarcophilus harrisii	78.68	0.00e+00	1048.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	35.82	7.00e-46	178.00
IUUC-Spo-108353	Schizosaccharomyces pombe	35.38	1.00e-49	190.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	35.90	3.00e-46	180.00
IUUC-Smo-108842	Selaginella moellendorffii	35.65	8.00e-28	116.00
IUUC-Sit-110781	Setaria italica	30.49	1.00e-45	177.00
IUUC-Sly-111797	Solanum lycopersicum	32.26	1.00e-43	171.00
IUUC-Stu-112188	Solanum tuberosum	35.09	2.00e-46	179.00
IUUC-Sbi-114862	Sorghum bicolor	31.68	2.00e-44	173.00
IUUC-Sre-115162	Sporisorium reilianum	33.67	9.00e-51	195.00
IUUC-Ssc-115505	Sus scrofa	92.22	2.00e-127	448.00
IUUC-Tgu-116535	Taeniopygia guttata	74.90	0.00e+00	975.00
IUUC-Tru-117542	Takifugu rubripes	75.06	8.00e-171	593.00
IUUC-Tni-120200	Tetraodon nigroviridis	57.05	0.00e+00	703.00
IUUC-Tca-121548	Theobroma cacao	34.92	5.00e-44	172.00
IUUC-Tre-122124	Trichoderma reesei	34.09	6.00e-48	186.00
IUUC-Tvi-122457	Trichoderma virens	32.37	2.00e-41	164.00
IUUC-Tae-125646	Triticum aestivum	32.16	8.00e-44	172.00
IUUC-Tme-127180	Tuber melanosporum	38.64	1.00e-57	217.00
IUUC-Tbe-127530	Tupaia belangeri	71.08	0.00e+00	932.00
IUUC-Ttr-128549	Tursiops truncatus	80.03	0.00e+00	1085.00
IUUC-Uma-129381	Ustilago maydis	32.60	9.00e-51	195.00
IUUC-Vda-129889	Verticillium dahliae	31.69	6.00e-40	159.00
IUUC-Vpa-130100	Vicugna pacos	82.08	0.00e+00	1085.00
IUUC-Vvi-131366	Vitis vinifera	35.88	8.00e-53	201.00
IUUC-Xtr-132048	Xenopus tropicalis	59.79	0.00e+00	779.00
IUUC-Xma-133593	Xiphophorus maculatus	74.22	6.00e-160	558.00
IUUC-Yli-134338	Yarrowia lipolytica	28.57	6.00e-30	125.00
IUUC-Zma-135586	Zea mays	29.53	1.00e-38	154.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence