iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068003

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02014379

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000025041.1	ENSMLUT00000024563.1	ENSMLUP00000017354.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.90e-68	229.1	414	792

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 414  GLINKGNWCYINATLQALVACPPMYHLMKF-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 500
           9***************************99.333333.334799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde........aeekk 134
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+ +                  k+ +++eee+e+  e s++        +    
   Q: 501  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLNlkkllspnndkfpisngPKSYSVNEEEQEEPGEGSEDeweqvgprN---- 585
           *9999999999966599********************445667888877887666544444444444444444444455555541.... PP
   S: 135  kkknk...........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck 212
               k           ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k k
   Q: 586  ----KtsvtrqadfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKTK 662
           ....444445555666***********9.688999999*******************99...****************8....99999* PP
   S: 213  kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYva 297
           +++e +++++l+klP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY++
   Q: 663  QEVEISRRVTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYPVDLEISKELLSPGVKNKNfkcHRTYRLFAVVYHHGsSATGGHYTT 750
           ***************************9998886.****************999988777777879*********************** PP
   S: 298  yvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
           +v +   + Wl++dD+ V+++++ +v++  + +taY+l+Y+r
   Q: 751  DVFQIGLNgWLRIDDQMVKVINQYQVVKPAAdRTAYLLYYRR 792
           ****87777*******************7779********98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

LKVHNFQYIF GDFSPDEFNQ FFVTPRSSVE LPPYNGSVLC GTQAADELPD GQEYQRIEFG 60
VNEVIESNDT LQRTPNYSIS STLNPQAPEF ILSCTTSKKT PDDIDKEANY SSIDCQYPGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGAAAGTAC ATAATTTGTA TAGTTTATGT GATCAATGAC TCTCTCTCTC TCTCTCTCTC 60
TCTCTCTCTC TTTCTTTCTC TCTTTTCCTT CAGTATATTT TTGGAGATTT TAGCCCTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.06	2.00e-44	174.00
IUUC-Aml-001584	Ailuropoda melanoleuca	88.40	0.00e+00	1319.00
IUUC-Atr-002927	Amborella trichopoda	35.22	5.00e-58	219.00
IUUC-Apl-003988	Anas platyrhynchos	78.89	0.00e+00	1151.00
IUUC-Aca-004461	Anolis carolinensis	88.32	3.00e-163	567.00
IUUC-Aly-006038	Arabidopsis lyrata	34.87	2.00e-54	206.00
IUUC-Ath-007328	Arabidopsis thaliana	34.62	3.00e-53	202.00
IUUC-Ago-007717	Ashbya gossypii	30.56	3.00e-43	170.00
IUUC-Acl-008188	Aspergillus clavatus	33.12	8.00e-62	232.00
IUUC-Afl-008456	Aspergillus flavus	37.42	9.00e-48	184.00
IUUC-Afu-009067	Aspergillus fumigatus	36.02	3.00e-64	239.00
IUUC-Ani-009483	Aspergillus nidulans	32.71	2.00e-61	230.00
IUUC-Ang-009639	Aspergillus niger	34.35	7.00e-60	225.00
IUUC-Aor-010040	Aspergillus oryzae	33.73	2.00e-59	224.00
IUUC-Ate-010310	Aspergillus terreus	30.99	3.00e-61	230.00
IUUC-Ame-011012	Astyanax mexicanus	73.71	2.00e-160	559.00
IUUC-Bgr-012311	Blumeria graminis	33.95	2.00e-43	170.00
IUUC-Bta-013299	Bos taurus	88.04	0.00e+00	1277.00
IUUC-Bci-013783	Botrytis cinerea	36.25	6.00e-58	219.00
IUUC-Bdi-015039	Brachypodium distachyon	31.78	8.00e-49	188.00
IUUC-Bol-015806	Brassica oleracea	36.92	2.00e-61	230.00
IUUC-Bra-017076	Brassica rapa	36.92	9.00e-62	231.00
IUUC-Cja-018715	Callithrix jacchus	85.98	0.00e+00	1301.00
IUUC-Cfa-020194	Canis familiaris	89.91	0.00e+00	1356.00
IUUC-Cpo-022272	Cavia porcellus	71.86	0.00e+00	997.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	33.11	1.00e-33	138.00
IUUC-Csa-023310	Chlorocebus sabaeus	87.63	0.00e+00	1328.00
IUUC-Cho-024966	Choloepus hoffmanni	77.14	0.00e+00	927.00
IUUC-Cin-025616	Ciona intestinalis	48.09	4.00e-105	375.00
IUUC-Csv-026043	Ciona savignyi	46.57	3.00e-98	351.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	33.60	1.00e-46	181.00
IUUC-Cne-026962	Cryptococcus neoformans	35.25	5.00e-49	190.00
IUUC-Cme-027113	Cyanidioschyzon merolae	30.44	3.00e-37	149.00
IUUC-Dre-028072	Danio rerio	77.68	0.00e+00	707.00
IUUC-Dno-029489	Dasypus novemcinctus	87.64	0.00e+00	1352.00
IUUC-Dor-031068	Dipodomys ordii	72.85	4.00e-133	468.00
IUUC-Dse-031553	Dothistroma septosporum	36.69	1.00e-56	214.00
IUUC-Dme-031759	Drosophila melanogaster	42.07	3.00e-82	301.00
IUUC-Ete-032549	Echinops telfairi	75.59	0.00e+00	837.00
IUUC-Eca-033380	Equus caballus	89.79	0.00e+00	1368.00
IUUC-Eeu-034818	Erinaceus europaeus	85.12	0.00e+00	1251.00
IUUC-Fca-035535	Felis catus	87.30	0.00e+00	1202.00
IUUC-Fal-036627	Ficedula albicollis	76.57	0.00e+00	1103.00
IUUC-Fox-037904	Fusarium oxysporum	36.87	3.00e-52	200.00
IUUC-Fso-038170	Fusarium solani	32.95	4.00e-51	196.00
IUUC-Gmo-039499	Gadus morhua	69.32	0.00e+00	655.00
IUUC-Ggr-040042	Gaeumannomyces graminis	35.36	2.00e-61	231.00
IUUC-Gga-040571	Gallus gallus	78.78	0.00e+00	1140.00
IUUC-Gac-041345	Gasterosteus aculeatus	78.80	0.00e+00	654.00
IUUC-Gma-043436	Glycine max	35.13	3.00e-59	222.00
IUUC-Ggo-044652	Gorilla gorilla	86.47	0.00e+00	1335.00
IUUC-Hsa-045864	Homo sapiens	86.59	0.00e+00	1338.00
IUUC-Hvu-047071	Hordeum vulgare	33.25	9.00e-53	201.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	88.51	0.00e+00	991.00
IUUC-Kpa-049132	Komagataella pastoris	30.94	1.00e-44	174.00
IUUC-Lch-050040	Latimeria chalumnae	69.86	0.00e+00	921.00
IUUC-Loc-052449	Lepisosteus oculatus	73.74	0.00e+00	699.00
IUUC-Lma-053248	Leptosphaeria maculans	35.73	1.00e-57	218.00
IUUC-Laf-054121	Loxodonta africana	86.27	0.00e+00	1298.00
IUUC-Mcc-055514	Macaca mulatta	87.25	0.00e+00	1322.00
IUUC-Meu-056873	Macropus eugenii	72.33	0.00e+00	818.00
IUUC-Mor-057243	Magnaporthe oryzae	33.42	6.00e-58	219.00
IUUC-Mpo-057439	Magnaporthe poae	35.62	4.00e-61	229.00
IUUC-Mtr-058457	Medicago truncatula	34.62	2.00e-57	216.00
IUUC-Mla-058929	Melampsora laricipopulina	31.40	1.00e-55	211.00
IUUC-Mga-060157	Meleagris gallopavo	77.56	0.00e+00	1139.00
IUUC-Mvi-060442	Microbotryum violaceum	34.07	2.00e-52	201.00
IUUC-Mmr-061062	Microcebus murinus	86.35	0.00e+00	1333.00
IUUC-Mdo-062798	Monodelphis domestica	80.30	0.00e+00	1201.00
IUUC-Mmu-064050	Mus musculus	80.60	0.00e+00	1225.00
IUUC-Mac-065202	Musa acuminata	33.67	7.00e-51	194.00
IUUC-Mpu-066554	Mustela putorius furo	87.28	0.00e+00	1298.00
IUUC-Nfi-068612	Neosartorya fischeri	34.62	4.00e-63	236.00
IUUC-Ncr-068878	Neurospora crassa	35.14	1.00e-52	201.00
IUUC-Nle-069661	Nomascus leucogenys	86.97	0.00e+00	1330.00
IUUC-Opr-070944	Ochotona princeps	76.27	2.00e-166	579.00
IUUC-Ont-071266	Oreochromis niloticus	57.73	0.00e+00	797.00
IUUC-Oan-073442	Ornithorhynchus anatinus	78.80	0.00e+00	1123.00
IUUC-Ocu-073788	Oryctolagus cuniculus	78.23	0.00e+00	1079.00
IUUC-Oba-075085	Oryza barthii	33.81	9.00e-37	147.00
IUUC-Obr-076663	Oryza brachyantha	32.40	4.00e-45	176.00
IUUC-Ogl-076937	Oryza glaberrima	30.02	1.00e-47	184.00
IUUC-Ogu-078909	Oryza glumaepatula	30.14	6.00e-46	179.00
IUUC-Oin-079617	Oryza indica	31.44	1.00e-47	184.00
IUUC-Olo-081043	Oryza longistaminata	26.02	1.00e-23	105.00
IUUC-Ome-081646	Oryza meridionalis	25.00	2.00e-22	101.00
IUUC-Oni-082914	Oryza nivara	30.14	4.00e-46	179.00
IUUC-Oru-084878	Oryza rufipogon	30.14	4.00e-46	179.00
IUUC-Osa-085822	Oryza sativa	30.77	8.00e-50	191.00
IUUC-Ola-086931	Oryzias latipes	57.32	0.00e+00	781.00
IUUC-Oga-088443	Otolemur garnettii	85.88	0.00e+00	1318.00
IUUC-Oar-089325	Ovis aries	85.23	0.00e+00	1179.00
IUUC-Ptr-091584	Pan troglodytes	83.33	0.00e+00	1242.00
IUUC-Pan-092551	Papio anubis	84.84	0.00e+00	1286.00
IUUC-Psi-093366	Pelodiscus sinensis	74.67	0.00e+00	679.00
IUUC-Pno-095136	Phaeosphaeria nodorum	35.23	8.00e-51	195.00
IUUC-Ppa-095574	Physcomitrella patens	35.87	5.00e-58	218.00
IUUC-Pfo-097462	Poecilia formosa	77.04	0.00e+00	687.00
IUUC-Pab-098547	Pongo abelii	86.97	0.00e+00	1326.00
IUUC-Pop-099529	Populus trichocarpa	37.18	3.00e-61	229.00
IUUC-Pca-101066	Procavia capensis	76.47	0.00e+00	1133.00
IUUC-Ppe-102110	Prunus persica	35.37	6.00e-59	221.00
IUUC-Pva-103015	Pteropus vampyrus	84.99	0.00e+00	1269.00
IUUC-Ptt-103998	Puccinia triticina	32.42	2.00e-52	200.00
IUUC-Pte-104417	Pyrenophora teres	33.58	4.00e-54	206.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.77	1.00e-53	205.00
IUUC-Rno-105533	Rattus norvegicus	82.00	0.00e+00	1233.00
IUUC-Sce-106160	Saccharomyces cerevisiae	27.84	7.00e-37	149.00
IUUC-Sha-106590	Sarcophilus harrisii	80.93	0.00e+00	1192.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	36.10	2.00e-57	216.00
IUUC-Spo-108353	Schizosaccharomyces pombe	36.99	7.00e-65	241.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	35.97	2.00e-58	220.00
IUUC-Smo-108842	Selaginella moellendorffii	36.92	6.00e-38	150.00
IUUC-Sit-110781	Setaria italica	31.75	7.00e-55	208.00
IUUC-Sly-111797	Solanum lycopersicum	33.76	4.00e-55	209.00
IUUC-Stu-112188	Solanum tuberosum	35.03	9.00e-56	211.00
IUUC-Sbi-114862	Sorghum bicolor	32.78	8.00e-45	174.00
IUUC-Sre-115162	Sporisorium reilianum	35.01	4.00e-66	246.00
IUUC-Ssc-115505	Sus scrofa	95.47	7.00e-165	572.00
IUUC-Tgu-116535	Taeniopygia guttata	76.67	0.00e+00	1114.00
IUUC-Tru-117542	Takifugu rubripes	55.94	0.00e+00	800.00
IUUC-Tni-120200	Tetraodon nigroviridis	58.04	0.00e+00	791.00
IUUC-Tca-121548	Theobroma cacao	35.24	3.00e-44	173.00
IUUC-Tre-122124	Trichoderma reesei	36.34	2.00e-60	227.00
IUUC-Tvi-122457	Trichoderma virens	34.63	7.00e-55	209.00
IUUC-Tae-125646	Triticum aestivum	34.43	6.00e-55	209.00
IUUC-Tme-127180	Tuber melanosporum	38.99	1.00e-69	257.00
IUUC-Tbe-127530	Tupaia belangeri	72.52	0.00e+00	999.00
IUUC-Ttr-128549	Tursiops truncatus	81.08	0.00e+00	1205.00
IUUC-Uma-129381	Ustilago maydis	33.20	3.00e-65	243.00
IUUC-Vda-129889	Verticillium dahliae	32.11	1.00e-51	198.00
IUUC-Vpa-130100	Vicugna pacos	82.12	0.00e+00	1223.00
IUUC-Vvi-131366	Vitis vinifera	36.39	2.00e-63	236.00
IUUC-Xtr-132048	Xenopus tropicalis	63.50	0.00e+00	907.00
IUUC-Xma-133593	Xiphophorus maculatus	77.52	0.00e+00	684.00
IUUC-Yli-134338	Yarrowia lipolytica	31.67	1.00e-33	138.00
IUUC-Zma-135586	Zea mays	31.66	1.00e-48	187.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence