iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065782

Ensembl Protein ID

ENSMPUP00000011627.1

UniProt Accession

M3YJX0; M3YJX0_MUSPF

Genbank Protein ID

ENSMPUP00000011627

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01041245

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000011721.1	ENSMPUT00000011819.1	ENSMPUP00000011627.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.08	0.00e+00	813.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MTSLSTSAQC STSDSACRIS PEQTNQVRPK QPLLKILQAA GAQGEMFTVK EVMHYLGQYI 60
MVKKLYDQRE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLITLA SATTDAAQTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTATCAGC AGACGGCAAT TTCTTCACTG CCAAAATGAC CTCACTTTCC ACCTCTGCCC 60
AGTGTTCAAC TTCTGACAGT GCTTGCAGGA TCTCTCCAGA ACAGACCAAT CAGGTAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	94.93	0.00e+00	839.00
IUUC-Apl-003800	Anas platyrhynchos	61.34	2.00e-155	542.00
IUUC-Aca-004608	Anolis carolinensis	57.78	3.00e-142	498.00
IUUC-Ame-010869	Astyanax mexicanus	46.98	4.00e-110	391.00
IUUC-Bta-013287	Bos taurus	88.64	0.00e+00	856.00
IUUC-Cja-019305	Callithrix jacchus	88.24	0.00e+00	798.00
IUUC-Cfa-020393	Canis familiaris	94.93	0.00e+00	864.00
IUUC-Cpo-022166	Cavia porcellus	87.18	0.00e+00	744.00
IUUC-Csa-023654	Chlorocebus sabaeus	91.08	0.00e+00	796.00
IUUC-Cho-024403	Choloepus hoffmanni	86.62	3.00e-123	434.00
IUUC-Dre-027754	Danio rerio	47.53	1.00e-117	416.00
IUUC-Dno-029630	Dasypus novemcinctus	86.84	0.00e+00	832.00
IUUC-Dor-031064	Dipodomys ordii	67.95	0.00e+00	648.00
IUUC-Ete-032901	Echinops telfairi	78.34	0.00e+00	753.00
IUUC-Eca-034234	Equus caballus	93.10	0.00e+00	931.00
IUUC-Eeu-035015	Erinaceus europaeus	64.37	2.00e-160	558.00
IUUC-Fca-036587	Felis catus	93.91	0.00e+00	861.00
IUUC-Fal-036906	Ficedula albicollis	52.74	1.00e-136	479.00
IUUC-Gmo-038646	Gadus morhua	45.67	2.00e-99	355.00
IUUC-Gga-040124	Gallus gallus	58.60	5.00e-113	400.00
IUUC-Gac-042397	Gasterosteus aculeatus	46.68	8.00e-110	390.00
IUUC-Ggo-045505	Gorilla gorilla	91.08	0.00e+00	816.00
IUUC-Hsa-046950	Homo sapiens	91.08	0.00e+00	816.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	88.84	0.00e+00	820.00
IUUC-Lch-050141	Latimeria chalumnae	53.57	3.00e-122	431.00
IUUC-Loc-051921	Lepisosteus oculatus	49.70	6.00e-119	421.00
IUUC-Laf-054281	Loxodonta africana	84.99	0.00e+00	774.00
IUUC-Mcc-055462	Macaca mulatta	87.45	0.00e+00	746.00
IUUC-Meu-056294	Macropus eugenii	71.01	3.00e-146	511.00
IUUC-Mga-059924	Meleagris gallopavo	60.40	8.00e-167	580.00
IUUC-Mmr-061428	Microcebus murinus	89.25	0.00e+00	851.00
IUUC-Mdo-062643	Monodelphis domestica	74.55	0.00e+00	717.00
IUUC-Mmu-063229	Mus musculus	81.95	0.00e+00	772.00
IUUC-Mlu-068105	Myotis lucifugus	81.17	0.00e+00	777.00
IUUC-Nle-069549	Nomascus leucogenys	91.48	0.00e+00	820.00
IUUC-Opr-070568	Ochotona princeps	87.15	0.00e+00	761.00
IUUC-Ont-072276	Oreochromis niloticus	46.12	7.00e-118	417.00
IUUC-Oan-072787	Ornithorhynchus anatinus	72.77	0.00e+00	656.00
IUUC-Ocu-074912	Oryctolagus cuniculus	87.63	0.00e+00	806.00
IUUC-Ola-087037	Oryzias latipes	44.84	6.00e-98	351.00
IUUC-Oga-088953	Otolemur garnettii	86.52	0.00e+00	797.00
IUUC-Oar-089202	Ovis aries	88.84	0.00e+00	862.00
IUUC-Ptr-090964	Pan troglodytes	91.48	0.00e+00	820.00
IUUC-Pan-091975	Papio anubis	90.87	0.00e+00	813.00
IUUC-Psi-093558	Pelodiscus sinensis	62.27	4.00e-162	564.00
IUUC-Pfo-096454	Poecilia formosa	48.69	3.00e-114	405.00
IUUC-Pab-098123	Pongo abelii	91.28	0.00e+00	820.00
IUUC-Pca-101112	Procavia capensis	78.95	0.00e+00	726.00
IUUC-Ppe-101490	Prunus persica	42.11	1.00e-08	54.70
IUUC-Pva-103098	Pteropus vampyrus	81.74	0.00e+00	771.00
IUUC-Rno-105930	Rattus norvegicus	82.59	0.00e+00	750.00
IUUC-Sha-107512	Sarcophilus harrisii	72.47	0.00e+00	636.00
IUUC-Sar-113584	Sorex araneus	81.34	0.00e+00	715.00
IUUC-Tgu-116766	Taeniopygia guttata	56.04	7.00e-100	356.00
IUUC-Tru-117829	Takifugu rubripes	47.67	6.00e-116	410.00
IUUC-Tsy-119268	Tarsius syrichta	76.27	0.00e+00	671.00
IUUC-Tni-120204	Tetraodon nigroviridis	46.54	1.00e-110	392.00
IUUC-Tbe-127840	Tupaia belangeri	82.96	1.00e-124	439.00
IUUC-Ttr-128863	Tursiops truncatus	89.05	0.00e+00	833.00
IUUC-Vpa-130718	Vicugna pacos	90.79	0.00e+00	806.00
IUUC-Xtr-132320	Xenopus tropicalis	44.90	7.00e-93	333.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence