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Tag Content
iUUCD ID IUUC-Dre-028180
Ensembl Protein ID ENSDARP00000095298.3
UniProt Accession F1QL52; F1QL52_DANRE
Genbank Protein ID ENSDARP00000095298
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID CR847979
Gene Name kmt2a; mll
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000004537.10 ENSDART00000148840.1 ENSDARP00000123761.1
ENSDARG00000004537.10 ENSDART00000104525.4 ENSDARP00000095298.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.10e-20 74.5 1675 1727
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           +C+vCg++++++k+l+eC+kCr+ +Hp+Cl+++  +++p+++k  w C+kC ++
   Q: 1675 FCHVCGRKYQKTKQLLECDKCRNSYHPECLGPN-HPTRPTKKKrvWVCTKCVRC 1727
           8********************************.*******999*******876 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MAHSCRWRFP ARPGGSSSSG TGRKAGRIRV NASLLISAGT NPNANGLGPG FDAALQVSAA 60
IGSNLQKFRD VLGESSGSSS GEEEFGGFTT VSDNRRLHSP GRTSIGSITP DKKPRGRPPR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028180|E3,PHD|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCGAAACAT GGATAATCCA TTTTGACCGC TAGACGCGAG CTGCCGTGTG CTGAGATCGC 60
TCGTTCGGGG CTACACCCAC ACTGAGCTCC TGATCCTAGG GCAGGCAGGC AGAGTGTAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028180|E3,PHD|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR002219--PE/DAG-bd
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50014--BROMODOMAIN_2
PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50081--ZF_DAG_PE_2
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
SMART

SM00297--BROMO
SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0021782--P:glial cell development
GO:0030097--P:hemopoiesis
GO:0035556--P:intracellular signal transduction
GO:0022008--P:neurogenesis
GO:0048823--P:nucleate erythrocyte development
GO:0048339--P:paraxial mesoderm development
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002274 Ailuropoda melanoleuca 68.31 0.00e+00 1154.00
IUUC-Apl-003478 Anas platyrhynchos 48.93 0.00e+00 1040.00
IUUC-Aca-005086 Anolis carolinensis 67.31 0.00e+00 1182.00
IUUC-Aly-006448 Arabidopsis lyrata 47.83 3.00e-39 157.00
IUUC-Ath-006690 Arabidopsis thaliana 47.74 7.00e-37 149.00
IUUC-Ame-011195 Astyanax mexicanus 63.85 0.00e+00 2850.00
IUUC-Bta-012974 Bos taurus 68.72 0.00e+00 1150.00
IUUC-Bol-016540 Brassica oleracea 40.28 8.00e-37 149.00
IUUC-Cja-019226 Callithrix jacchus 68.27 0.00e+00 1146.00
IUUC-Cfa-021049 Canis familiaris 67.95 0.00e+00 1150.00
IUUC-Cpo-021459 Cavia porcellus 68.23 0.00e+00 1131.00
IUUC-Csa-023434 Chlorocebus sabaeus 68.71 0.00e+00 1147.00
IUUC-Cho-024652 Choloepus hoffmanni 66.99 0.00e+00 937.00
IUUC-Csv-026268 Ciona savignyi 35.36 1.00e-124 442.00
IUUC-Dor-030550 Dipodomys ordii 61.07 0.00e+00 931.00
IUUC-Ete-032834 Echinops telfairi 44.92 0.00e+00 867.00
IUUC-Eca-033615 Equus caballus 68.36 0.00e+00 1137.00
IUUC-Eeu-035136 Erinaceus europaeus 58.82 0.00e+00 747.00
IUUC-Fal-037256 Ficedula albicollis 65.10 0.00e+00 1183.00
IUUC-Fox-037866 Fusarium oxysporum 25.64 1.30e-02 35.80
IUUC-Gmo-038641 Gadus morhua 68.89 0.00e+00 1130.00
IUUC-Gga-040828 Gallus gallus 67.99 0.00e+00 1163.00
IUUC-Gac-041452 Gasterosteus aculeatus 51.34 0.00e+00 1298.00
IUUC-Gma-043554 Glycine max 48.70 2.00e-38 155.00
IUUC-Ggo-045124 Gorilla gorilla 48.43 0.00e+00 986.00
IUUC-Hsa-046143 Homo sapiens 68.35 0.00e+00 1149.00
IUUC-Itr-049024 Ictidomys tridecemlineatus 65.66 0.00e+00 1082.00
IUUC-Lch-049704 Latimeria chalumnae 65.88 0.00e+00 1115.00
IUUC-Loc-052181 Lepisosteus oculatus 59.40 0.00e+00 2783.00
IUUC-Laf-053946 Loxodonta africana 68.04 0.00e+00 1139.00
IUUC-Mcc-055508 Macaca mulatta 67.83 0.00e+00 1143.00
IUUC-Mtr-058327 Medicago truncatula 39.56 6.00e-38 153.00
IUUC-Mga-059943 Meleagris gallopavo 69.34 0.00e+00 1172.00
IUUC-Mmr-061178 Microcebus murinus 68.19 0.00e+00 1152.00
IUUC-Mdo-063031 Monodelphis domestica 68.71 0.00e+00 1160.00
IUUC-Mmu-063650 Mus musculus 67.88 0.00e+00 1129.00
IUUC-Mpu-066495 Mustela putorius furo 68.59 0.00e+00 1143.00
IUUC-Mlu-068045 Myotis lucifugus 64.64 0.00e+00 1140.00
IUUC-Nle-069064 Nomascus leucogenys 68.03 0.00e+00 1145.00
IUUC-Opr-071043 Ochotona princeps 66.11 0.00e+00 1048.00
IUUC-Ont-072556 Oreochromis niloticus 56.79 0.00e+00 2482.00
IUUC-Oan-073324 Ornithorhynchus anatinus 67.13 0.00e+00 1022.00
IUUC-Ocu-074190 Oryctolagus cuniculus 69.26 0.00e+00 1141.00
IUUC-Oba-075647 Oryza barthii 48.08 2.00e-37 151.00
IUUC-Olo-080577 Oryza longistaminata 46.79 1.00e-35 145.00
IUUC-Ome-081214 Oryza meridionalis 48.08 2.00e-37 151.00
IUUC-Oni-083000 Oryza nivara 48.08 2.00e-37 151.00
IUUC-Opu-083842 Oryza punctata 48.08 2.00e-37 151.00
IUUC-Oru-084361 Oryza rufipogon 48.08 2.00e-37 151.00
IUUC-Ola-087176 Oryzias latipes 67.66 0.00e+00 1198.00
IUUC-Olu-087718 Ostreococcus lucimarinus 43.87 6.00e-37 150.00
IUUC-Oga-088208 Otolemur garnettii 68.32 0.00e+00 1137.00
IUUC-Oar-090152 Ovis aries 68.60 0.00e+00 1147.00
IUUC-Ptr-091127 Pan troglodytes 68.35 0.00e+00 1148.00
IUUC-Pan-092679 Papio anubis 68.07 0.00e+00 1140.00
IUUC-Psi-094059 Pelodiscus sinensis 49.35 0.00e+00 1071.00
IUUC-Pma-094258 Petromyzon marinus 51.35 1.00e-163 570.00
IUUC-Pfo-096536 Poecilia formosa 51.91 0.00e+00 1281.00
IUUC-Pab-098262 Pongo abelii 68.35 0.00e+00 1150.00
IUUC-Pca-100358 Procavia capensis 63.84 0.00e+00 986.00
IUUC-Pva-102522 Pteropus vampyrus 60.00 0.00e+00 929.00
IUUC-Rno-105200 Rattus norvegicus 68.06 0.00e+00 1115.00
IUUC-Sha-107174 Sarcophilus harrisii 68.93 0.00e+00 1175.00
IUUC-Smo-109164 Selaginella moellendorffii 47.40 7.00e-39 156.00
IUUC-Sly-111176 Solanum lycopersicum 46.95 3.00e-37 150.00
IUUC-Tgu-117047 Taeniopygia guttata 65.43 0.00e+00 1195.00
IUUC-Tru-118328 Takifugu rubripes 50.89 0.00e+00 1283.00
IUUC-Tsy-118953 Tarsius syrichta 45.94 0.00e+00 826.00
IUUC-Tni-120837 Tetraodon nigroviridis 67.79 0.00e+00 1176.00
IUUC-Tbe-127950 Tupaia belangeri 66.34 0.00e+00 852.00
IUUC-Ttr-128643 Tursiops truncatus 63.23 0.00e+00 1054.00
IUUC-Vpa-130660 Vicugna pacos 69.32 0.00e+00 957.00
IUUC-Xtr-132869 Xenopus tropicalis 62.50 0.00e+00 1083.00
Created Date 25-Jun-2017

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