iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000006974.5	ENSPTRT00000074545.1	ENSPTRP00000060595.1
ENSPTRG00000006974.5	ENSPTRT00000012865.5	ENSPTRP00000011910.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-19	68.8	1366	1406
UBD/Beta-Prp	5.80e-44	150.4	1466	1600

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtl...lvsGsdDgtikvWDlrtgvll 36
           gHt++v+cl     s+     l +Gs D+ti+++++++  ++
   Q: 1366 GHTSKVNCLLVtqtSG-KnaaLYTGSSDHTIRCYNVKSRECV 1406
           8*******95587533.24579**************988876 PP

UBD/Beta-Prp

   S: 21   dksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
            ++ll++gs+d ti v d+++g llr+l+gh++++ ++k  +d  +  +gs+D+ ++  ++ tg+ v+++kgh++ v+ +++    +
   Q: 1466 ARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVND--LVFSGSSDQSVHAHNIHTGELVRIYKGHNHAVTVVNILG--K 1548
           5689***************************************..9*************************************9..* PP
   S: 108  klvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvr 162
           ++v++  d+ +rv++l++   l+ +  gh+++++c+++h+  +++ +G++D+ ++
   Q: 1549 VMVTACLDKFVRVYELQSHDRLQ-VYGGHKDMIMCMTIHK--SMIYTGCYDGSIQ 1600
           ***********************.****************..**********997 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MPVGRIECPS SPSFPRDISH ECRVCGVTEV GLSAYAKHIS GQLHKDNVDA QEREDDGKGE 60
EEEEDYFDKE LVQLIKQRKE QSRSPDRYQE NDNTVTYRSS DFTDNFSEGL DFNFEQLESQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGGCGGG GAGCGGGTCC GGAGCAGGCT CCCGGACCCA AAACTGAAGG GGGCGTCTGA 60
GGCGTCAGGG AGCTCCCTCG CCTGGCCCTC GGCGGCCTGA TGGAGTAAGA GGGGTTGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013087--Znf_C2H2_type

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00028--ZINC_FINGER_C2H2_1

Pfam

PF00400--WD40

SMART

SM00320--WD40
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0046872--F:metal ion binding
GO:0003723--F:RNA binding
GO:0017124--F:SH3 domain binding
GO:0008286--P:insulin receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001928	Ailuropoda melanoleuca	85.91	0.00e+00	2639.00
IUUC-Apl-003674	Anas platyrhynchos	58.17	0.00e+00	1503.00
IUUC-Aca-005018	Anolis carolinensis	55.21	0.00e+00	1431.00
IUUC-Ame-011431	Astyanax mexicanus	68.95	0.00e+00	686.00
IUUC-Bta-013436	Bos taurus	86.58	0.00e+00	2626.00
IUUC-Cfa-020278	Canis familiaris	84.20	0.00e+00	2100.00
IUUC-Cpo-022278	Cavia porcellus	80.79	0.00e+00	2317.00
IUUC-Csa-023115	Chlorocebus sabaeus	93.31	0.00e+00	1557.00
IUUC-Cho-024829	Choloepus hoffmanni	79.54	0.00e+00	1699.00
IUUC-Dre-028112	Danio rerio	65.18	0.00e+00	668.00
IUUC-Dno-029127	Dasypus novemcinctus	83.25	0.00e+00	2544.00
IUUC-Dor-030367	Dipodomys ordii	81.30	0.00e+00	1216.00
IUUC-Ete-032500	Echinops telfairi	78.93	0.00e+00	1160.00
IUUC-Eca-034319	Equus caballus	87.55	0.00e+00	2617.00
IUUC-Eeu-034754	Erinaceus europaeus	75.34	0.00e+00	1967.00
IUUC-Fca-036181	Felis catus	86.71	0.00e+00	2547.00
IUUC-Fal-036865	Ficedula albicollis	57.47	0.00e+00	1386.00
IUUC-Gmo-039227	Gadus morhua	64.30	3.00e-176	611.00
IUUC-Gga-041178	Gallus gallus	58.13	0.00e+00	1515.00
IUUC-Gac-042209	Gasterosteus aculeatus	58.07	2.00e-169	589.00
IUUC-Ggo-044636	Gorilla gorilla	97.58	0.00e+00	2967.00
IUUC-Hsa-045949	Homo sapiens	98.01	0.00e+00	2987.00
IUUC-Itr-048628	Ictidomys tridecemlineatus	87.77	0.00e+00	2663.00
IUUC-Lch-049753	Latimeria chalumnae	52.81	0.00e+00	1290.00
IUUC-Loc-052333	Lepisosteus oculatus	69.14	0.00e+00	730.00
IUUC-Laf-053530	Loxodonta africana	83.08	0.00e+00	2515.00
IUUC-Mcc-054664	Macaca mulatta	95.83	0.00e+00	2881.00
IUUC-Meu-056609	Macropus eugenii	67.13	0.00e+00	1236.00
IUUC-Mga-059632	Meleagris gallopavo	58.24	0.00e+00	1485.00
IUUC-Mmr-060742	Microcebus murinus	87.26	0.00e+00	2659.00
IUUC-Mdo-061831	Monodelphis domestica	82.33	0.00e+00	1338.00
IUUC-Mmu-064055	Mus musculus	74.28	0.00e+00	2165.00
IUUC-Mpu-066458	Mustela putorius furo	92.37	0.00e+00	1589.00
IUUC-Mlu-067767	Myotis lucifugus	83.21	0.00e+00	2516.00
IUUC-Nle-069728	Nomascus leucogenys	96.46	0.00e+00	2957.00
IUUC-Opr-070914	Ochotona princeps	79.33	0.00e+00	2344.00
IUUC-Ont-072462	Oreochromis niloticus	56.96	4.00e-164	571.00
IUUC-Ocu-073827	Oryctolagus cuniculus	86.46	0.00e+00	2555.00
IUUC-Ola-087573	Oryzias latipes	68.23	3.00e-163	568.00
IUUC-Oga-088664	Otolemur garnettii	89.74	0.00e+00	1877.00
IUUC-Oar-090256	Ovis aries	82.72	0.00e+00	1939.00
IUUC-Pan-091779	Papio anubis	93.42	0.00e+00	1559.00
IUUC-Psi-093267	Pelodiscus sinensis	93.09	4.00e-166	576.00
IUUC-Pma-094414	Petromyzon marinus	43.84	5.00e-60	226.00
IUUC-Pfo-097009	Poecilia formosa	63.99	5.00e-160	559.00
IUUC-Pca-100820	Procavia capensis	76.98	0.00e+00	1719.00
IUUC-Pva-103044	Pteropus vampyrus	98.66	0.00e+00	806.00
IUUC-Rno-105960	Rattus norvegicus	69.30	0.00e+00	1941.00
IUUC-Sar-113018	Sorex araneus	86.28	0.00e+00	996.00
IUUC-Ssc-115278	Sus scrofa	86.58	0.00e+00	2640.00
IUUC-Tgu-117231	Taeniopygia guttata	56.96	0.00e+00	1457.00
IUUC-Tru-118472	Takifugu rubripes	55.73	2.00e-165	577.00
IUUC-Tsy-118877	Tarsius syrichta	85.74	0.00e+00	2107.00
IUUC-Tni-119881	Tetraodon nigroviridis	56.81	1.00e-177	617.00
IUUC-Tbe-127499	Tupaia belangeri	78.56	0.00e+00	1359.00
IUUC-Ttr-128962	Tursiops truncatus	87.08	0.00e+00	2618.00
IUUC-Vpa-130089	Vicugna pacos	82.53	0.00e+00	1360.00
IUUC-Xtr-132940	Xenopus tropicalis	59.42	0.00e+00	889.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence