iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024186

Ensembl Protein ID

ENSCSAP00000016678.1

UniProt Accession

A0A0D9S739; A0A0D9S739_CHLSB

Genbank Protein ID

ENSCSAP00000016678

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01133066

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000001339.1	ENSCSAT00000017194.1	ENSCSAP00000016678.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-86	290.0	81	784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l++e+++++kg          el++slq+l+ ++       +     
   Q: 81   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHlfniisRKKEALKDEANQKDKGnckedslasyELICSLQSLIISVeqlqasfLlnpek 169
           6************************************999999999999999999999*****99999999999995555555144555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde.... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                  e  ++kee+++ ++ e++++    
   Q: 170  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeevknvaelptkveEIPHQKEEMSGINSMEMDSMrhse 258
           88888*****************************************545556677776666666656666666666666666666**** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 259  dckeklpkgngkrksdtefgnmkkkvkvskehqsleenqrqtrskrkatidtleippkiipkcisenesprpsqkksrvkinwlksatk 347
           ***************************************************************************************** PP
   S: 130  .............................................................aeekkkkknk.....slisdlFqgqlks 152
                                                                        +e k+ +k++     +l+++lFqgql  
   Q: 348  qpsilskfcslgkittnqgakgqskeneydpeedlgkyesdntthacgfespgntvtpvnvNEVKPINKGEeqigfELVEKLFQGQLVL 436
           ***********************************************************99555555555556666************* PP
   S: 153  qikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqeaekklklkklP 227
           +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c++++eae++l ++k+P
   Q: 437  RTRCLECESLTERREDFQDISVPVQEDELSKVEesseispepktemkTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMP 525
           ****************************99998******************************************************** PP
   S: 228  evLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn......... 301
           ev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGHY+a vk          
   Q: 526  EVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGHYTASVKVtdlnsleld 609
           *********************************************99.....678********************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 610  kgnfvvdqmceigkpeplneeeargvvenyddeevsirvggntqpskvlnkknveavgllggqkskadyelynkasnpdkvastvfaen 698
           ***************************************************************************************** PP
   S: 302  ............................................ekgkWllfdDskVtevkeeevleetg......staYvlfYkr 337
                                                        +gkWllfdDs+V++++e+++l++ +      st+Y+lfYk+
   Q: 699  rnsetndtngthesdrnkessdqtgvnisgfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpstsptSTPYLLFYKK 784
           ********9999999999999999999999988888888877766999*******************888**************97 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MPGVIPSESN GLSRGSPSKK NRLSLKFFQK KETKRALDFT DSQENEEKAS EYRASEIDQV 60
VPAAQSSPIN CEKRENLLPF VGLNNLGNTC YLNSILQVLY FCPGFKSGVK HLFNIISRKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATAATTGA TTACAACTTT CCTCTATAAA TTAATTATTG ACAACTCCTT GGGATTTGAG 60
AAAAAAATGC CTGGTGTCAT ACCTAGTGAA AGTAATGGAC TTTCAAGAGG TAGCCCATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

csab:103224705

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	93.77	0.00e+00	1425.00
IUUC-Apl-004204	Anas platyrhynchos	73.55	0.00e+00	945.00
IUUC-Aca-004637	Anolis carolinensis	65.83	0.00e+00	931.00
IUUC-Ame-011718	Astyanax mexicanus	48.20	2.00e-172	599.00
IUUC-Bta-012552	Bos taurus	92.36	0.00e+00	1412.00
IUUC-Cja-019588	Callithrix jacchus	97.20	0.00e+00	1516.00
IUUC-Cfa-020211	Canis familiaris	94.52	0.00e+00	1448.00
IUUC-Cpo-021551	Cavia porcellus	84.84	0.00e+00	1276.00
IUUC-Cho-024739	Choloepus hoffmanni	83.19	0.00e+00	754.00
IUUC-Dre-028184	Danio rerio	50.18	4.00e-177	614.00
IUUC-Dno-029669	Dasypus novemcinctus	90.23	0.00e+00	1393.00
IUUC-Dor-030168	Dipodomys ordii	87.82	0.00e+00	1274.00
IUUC-Dme-031732	Drosophila melanogaster	28.77	5.00e-18	87.00
IUUC-Ete-032825	Echinops telfairi	86.46	0.00e+00	960.00
IUUC-Eca-033595	Equus caballus	93.68	0.00e+00	1354.00
IUUC-Eeu-034877	Erinaceus europaeus	80.78	2.00e-162	565.00
IUUC-Fca-035381	Felis catus	93.53	0.00e+00	1006.00
IUUC-Fal-037592	Ficedula albicollis	69.26	0.00e+00	963.00
IUUC-Gmo-039680	Gadus morhua	44.65	9.00e-153	533.00
IUUC-Gga-041196	Gallus gallus	72.60	0.00e+00	1061.00
IUUC-Gac-042292	Gasterosteus aculeatus	48.74	6.00e-145	508.00
IUUC-Ggo-044671	Gorilla gorilla	97.71	0.00e+00	1533.00
IUUC-Hsa-047020	Homo sapiens	97.45	0.00e+00	1527.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	85.50	0.00e+00	1276.00
IUUC-Lch-050543	Latimeria chalumnae	57.35	0.00e+00	711.00
IUUC-Loc-052338	Lepisosteus oculatus	52.30	0.00e+00	699.00
IUUC-Laf-053707	Loxodonta africana	90.49	0.00e+00	1407.00
IUUC-Mcc-055885	Macaca mulatta	99.24	0.00e+00	1565.00
IUUC-Meu-056573	Macropus eugenii	67.21	0.00e+00	949.00
IUUC-Mga-059346	Meleagris gallopavo	73.39	0.00e+00	1012.00
IUUC-Mmr-061612	Microcebus murinus	94.01	0.00e+00	1409.00
IUUC-Mdo-062887	Monodelphis domestica	72.31	0.00e+00	1056.00
IUUC-Mmu-064044	Mus musculus	88.68	0.00e+00	1377.00
IUUC-Mpu-066847	Mustela putorius furo	94.65	0.00e+00	1441.00
IUUC-Mlu-067684	Myotis lucifugus	91.36	0.00e+00	1423.00
IUUC-Nle-070057	Nomascus leucogenys	98.09	0.00e+00	1539.00
IUUC-Opr-070463	Ochotona princeps	84.57	0.00e+00	1265.00
IUUC-Ont-071975	Oreochromis niloticus	45.75	8.00e-152	530.00
IUUC-Oan-073062	Ornithorhynchus anatinus	85.71	8.00e-47	179.00
IUUC-Ocu-074840	Oryctolagus cuniculus	93.63	0.00e+00	1440.00
IUUC-Ola-087088	Oryzias latipes	46.75	2.00e-173	602.00
IUUC-Oga-088472	Otolemur garnettii	93.12	0.00e+00	1434.00
IUUC-Oar-089498	Ovis aries	92.87	0.00e+00	1420.00
IUUC-Ptr-091395	Pan troglodytes	97.83	0.00e+00	1531.00
IUUC-Pan-092462	Papio anubis	99.36	0.00e+00	1566.00
IUUC-Psi-093583	Pelodiscus sinensis	72.51	0.00e+00	912.00
IUUC-Pma-094644	Petromyzon marinus	36.78	9.00e-29	120.00
IUUC-Pfo-096314	Poecilia formosa	47.29	3.00e-168	585.00
IUUC-Pab-098568	Pongo abelii	98.22	0.00e+00	1540.00
IUUC-Pca-100948	Procavia capensis	81.32	0.00e+00	1238.00
IUUC-Pva-102853	Pteropus vampyrus	93.37	0.00e+00	1441.00
IUUC-Rno-105573	Rattus norvegicus	88.66	0.00e+00	1361.00
IUUC-Sha-107495	Sarcophilus harrisii	72.05	0.00e+00	890.00
IUUC-Sar-113545	Sorex araneus	77.42	0.00e+00	1102.00
IUUC-Ssc-115962	Sus scrofa	93.92	0.00e+00	1458.00
IUUC-Tgu-116731	Taeniopygia guttata	69.57	0.00e+00	978.00
IUUC-Tru-117893	Takifugu rubripes	46.96	2.00e-158	552.00
IUUC-Tsy-119644	Tarsius syrichta	84.95	0.00e+00	1258.00
IUUC-Tni-119819	Tetraodon nigroviridis	45.40	3.00e-169	588.00
IUUC-Tbe-127272	Tupaia belangeri	89.03	0.00e+00	1263.00
IUUC-Ttr-128404	Tursiops truncatus	93.88	0.00e+00	1459.00
IUUC-Vpa-130205	Vicugna pacos	93.11	0.00e+00	1442.00
IUUC-Xtr-132613	Xenopus tropicalis	56.30	0.00e+00	745.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence