iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071975

Ensembl Protein ID

ENSONIP00000011109.1

UniProt Accession

I3JQG5; I3JQG5_ORENI

Genbank Protein ID

ENSONIP00000011109

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01028157

Gene Name

usp1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000008834.1	ENSONIT00000011118.1	ENSONIP00000011109.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-82	278.3	91	813

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg.......................ellkslqklfeelw..... 61
           +Gl+NlgNtCY+NS+LQ+L+ +p +re +++ +  ++++e+pke+++                       +l++++++l ++++     
   Q: 91   VGLNNLGNTCYLNSILQVLYYCPGFREGIKKLHDLSIQKEKPKEETEkseesdgvsealpahiellgsfnTLITAVEQLQSSFLlnpds 179
           6******************************8888888887744444555666677777777755555557777777777777655555 PP
   S: 62   .kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.................... 129
            ++ + a+ pr++l++l++++++++gy q+DaqE+l+++l  ++e+++  +++ k e+eeed se + e                    
   Q: 180  fTDGELATPPRKILHTLRQLNPMYEGYLQHDAQEVLQCILGYIQEACDTIRKELKVESEEEDVSEVKLEngldlgsggsgaepkastee 268
           566666*****************************************776666666666666555555589****************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 269  dgqvagkrksdtevgnakkkskslkskksdsaeenlsrnrpltrskrkssseinmdssqnkggeedageeetkkpnkrkkraklnwlrp 357
           ***************************************************************************************** PP
   S: 130  ..................................................................aeekkkkknkslisdlFqgqlks 152
                                                                                +  + + sl+++lFqg+l  
   Q: 358  sgkqpsifskfrsvgkiscttvknqkkteqengvthdqseknlqepssqnasehskapkhqgaytnCGFSVRSAGLSLMEHLFQGRLVL 446
           **********************************************999988877766666666665556666666************* PP
   S: 153  qikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqeaekklklkklP 227
           +++clec++ ++r+e+f+d+s+pv +++ +++               +l++++++f++ e++ ge+ky+ce+c++++eae++l ++k P
   Q: 447  RTRCLECESFTERREDFQDISVPVLDDQPSSPGdlsevspdpkpelkTLKWAISQFASVERIFGEDKYFCETCHHYTEAERSLLFDKTP 535
           ****************************765559******************************************************* PP
   S: 228  evLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn......... 301
           ev+++hLkRf     + + +    +k+n+ +++pl+L+l+++ct++++++   ++Y+L+avv+HsG ++ssGHY+ay++          
   Q: 536  EVITIHLKRFsanglELDPY-AGLSKVNTPLQTPLTLSLEEWCTQSSSTK--GQNYQLFAVVMHSGvTISSGHYTAYIRMsdltdvkiw 621
           **********6666666666.4557********************88776..9************************************ PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 622  lqdtkteekkeeedevkedkegalvkekvldyddgevsfslntrgqrrkslassksgskklseggvgllggqrslssydlgnsssskht 710
           ***************************************************************************************** PP
   S: 302  ............................................................ekgkWllfdDskVtevkeeevleetg... 327
                                                                        +gkWllfdDs+V+  +ee++l+ ++   
   Q: 711  ekaassgstegcnrrktinilsqnteaglkkepeaveeasqascgstetkeqqalnslleYEGKWLLFDDSEVRLFEEEDFLRACSpet 799
           *************************999999999999999999999988888777777766999*******************999*** PP
   S: 328  ...staYvlfYkrr 338
              st+Y+lfY+r+
   Q: 800  ccsSTPYLLFYRRM 813
           ************96 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MPGLQGESVV VAAPGSPVKK SKLSLKFFQK KETKRALDFS EPQTEEPKTC EPEEPEPISS 60
CDQVVPGPSQ CPSSPSLLLS CEKRENLVPF VGLNNLGNTC YLNSILQVLY YCPGFREGIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAGGTC TGCAGGGTGA AAGTGTGGTA GTAGCGGCTC CGGGGAGCCC AGTGAAGAAG 60
AGCAAACTCT CTCTGAAGTT CTTCCAGAAG AAGGAAACCA AGCGGGCTCT GGATTTCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	48.00	3.00e-174	605.00
IUUC-Apl-004204	Anas platyrhynchos	47.52	1.00e-157	550.00
IUUC-Aca-004637	Anolis carolinensis	48.31	2.00e-173	602.00
IUUC-Ame-011718	Astyanax mexicanus	54.98	0.00e+00	719.00
IUUC-Bta-012552	Bos taurus	47.41	5.00e-175	608.00
IUUC-Cja-019588	Callithrix jacchus	47.70	3.00e-174	605.00
IUUC-Cfa-020211	Canis familiaris	47.76	3.00e-174	605.00
IUUC-Cpo-021551	Cavia porcellus	48.22	1.00e-168	586.00
IUUC-Csa-024186	Chlorocebus sabaeus	47.19	1.00e-174	606.00
IUUC-Cho-024739	Choloepus hoffmanni	41.58	1.00e-73	270.00
IUUC-Dre-028184	Danio rerio	56.18	0.00e+00	733.00
IUUC-Dno-029669	Dasypus novemcinctus	47.48	5.00e-171	595.00
IUUC-Dor-030168	Dipodomys ordii	45.47	2.00e-151	530.00
IUUC-Dme-031732	Drosophila melanogaster	33.16	2.00e-22	102.00
IUUC-Ete-032825	Echinops telfairi	45.97	2.00e-105	377.00
IUUC-Eca-033595	Equus caballus	47.18	9.00e-160	557.00
IUUC-Eeu-034877	Erinaceus europaeus	47.81	2.00e-65	243.00
IUUC-Fca-035381	Felis catus	50.35	8.00e-135	474.00
IUUC-Fal-037592	Ficedula albicollis	48.21	3.00e-163	569.00
IUUC-Gmo-039680	Gadus morhua	57.66	0.00e+00	735.00
IUUC-Gga-041196	Gallus gallus	47.54	6.00e-173	601.00
IUUC-Gac-042292	Gasterosteus aculeatus	63.01	0.00e+00	801.00
IUUC-Ggo-044671	Gorilla gorilla	47.58	3.00e-173	602.00
IUUC-Hsa-047020	Homo sapiens	47.34	5.00e-173	601.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	43.58	5.00e-144	504.00
IUUC-Lch-050543	Latimeria chalumnae	45.70	1.00e-152	533.00
IUUC-Loc-052338	Lepisosteus oculatus	53.60	0.00e+00	713.00
IUUC-Laf-053707	Loxodonta africana	47.39	3.00e-170	592.00
IUUC-Mcc-055885	Macaca mulatta	46.95	3.00e-174	605.00
IUUC-Meu-056573	Macropus eugenii	46.67	2.00e-141	496.00
IUUC-Mga-059346	Meleagris gallopavo	47.41	6.00e-163	568.00
IUUC-Mmr-061612	Microcebus murinus	46.85	5.00e-169	588.00
IUUC-Mdo-062887	Monodelphis domestica	49.04	1.00e-166	580.00
IUUC-Mmu-064044	Mus musculus	47.69	6.00e-172	597.00
IUUC-Mpu-066847	Mustela putorius furo	48.00	3.00e-175	608.00
IUUC-Mlu-067684	Myotis lucifugus	47.47	8.00e-172	597.00
IUUC-Nle-070057	Nomascus leucogenys	47.64	3.00e-174	605.00
IUUC-Opr-070463	Ochotona princeps	46.10	6.00e-112	398.00
IUUC-Ocu-074840	Oryctolagus cuniculus	47.52	4.00e-174	605.00
IUUC-Ola-087088	Oryzias latipes	62.98	0.00e+00	872.00
IUUC-Oga-088472	Otolemur garnettii	46.90	1.00e-168	587.00
IUUC-Oar-089498	Ovis aries	46.89	3.00e-175	608.00
IUUC-Ptr-091395	Pan troglodytes	47.46	4.00e-173	602.00
IUUC-Pan-092462	Papio anubis	46.95	3.00e-174	605.00
IUUC-Psi-093583	Pelodiscus sinensis	49.57	4.00e-144	505.00
IUUC-Pma-094644	Petromyzon marinus	36.68	2.00e-29	122.00
IUUC-Pfo-096314	Poecilia formosa	66.19	0.00e+00	923.00
IUUC-Pab-098568	Pongo abelii	47.39	4.00e-174	605.00
IUUC-Pca-100948	Procavia capensis	46.46	6.00e-76	278.00
IUUC-Pva-102853	Pteropus vampyrus	47.65	6.00e-173	601.00
IUUC-Rno-105573	Rattus norvegicus	47.06	1.00e-170	593.00
IUUC-Sha-107495	Sarcophilus harrisii	47.32	7.00e-135	474.00
IUUC-Sar-113545	Sorex araneus	42.06	7.00e-127	448.00
IUUC-Ssc-115962	Sus scrofa	48.60	3.00e-173	602.00
IUUC-Tgu-116731	Taeniopygia guttata	47.47	2.00e-164	572.00
IUUC-Tru-117893	Takifugu rubripes	66.75	0.00e+00	872.00
IUUC-Tsy-119644	Tarsius syrichta	47.88	3.00e-76	280.00
IUUC-Tni-119819	Tetraodon nigroviridis	63.38	0.00e+00	835.00
IUUC-Tbe-127272	Tupaia belangeri	44.91	2.00e-140	493.00
IUUC-Ttr-128404	Tursiops truncatus	48.34	2.00e-178	619.00
IUUC-Vpa-130205	Vicugna pacos	47.34	5.00e-169	588.00
IUUC-Xtr-132613	Xenopus tropicalis	45.62	4.00e-163	568.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence