iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067085

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AAPE02055399

Gene Name

USP22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006705.2	ENSMLUT00000006709.2	ENSMLUP00000006125.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.70e-30	104.7	121	251

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ ++++++ +   +p+ +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 121  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHRCEMQ---SPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQ 205
           9*****************************.99999875...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlks 152
           Da+Efl   ld l++++k                  ++ ++ +++++ +++i+++F g l+s
   Q: 206  DAHEFLIAALDVLHRHCKG----------------DDNGKKASNPNHCNCIIDQIFTGGLQS 251
           *****************32................22335677899999********99987 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

QAKSCVCHVC GVHLSRLHSC LHCVFFGCFT KKHIHEHAKS KRHNLAIELM YGGIYCFLCQ 60
DYIYDKDMET IAKEEQRKAW KLQGVGEKFS TWEPSKRELE LLKHNPKRRK ITSNCTIGLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCCAAGT CCTGCGTCTG CCACGTCTGT GGAGTCCACC TGAGCAGGCT GCACTCCTGC 60
CTCCACTGTG TCTTCTTTGG CTGTTTCACA AAGAAGCACA TTCACGAACA TGCGAAGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024938	Choloepus hoffmanni	93.97	1.00e-63	237.00
IUUC-Dor-030481	Dipodomys ordii	95.95	3.00e-98	352.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence