iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-104936

Ensembl Protein ID

ENSRNOP00000061354.3

UniProt Accession

D4A0M9; D4A0M9_RAT

Genbank Protein ID

ENSRNOP00000061354

Protein Name

WD repeat domain 64

Genbank Nucleotide ID

AABR07021822

Gene Name

Wdr64

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000038083.5	ENSRNOT00000065706.4	ENSRNOP00000061354.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-22	78.6	514	543
UBD/Beta-Prp	3.90e-40	138.3	129	450

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 7    tclafsd..tllvsGsdDgtikvWDlrtgv 34
           tc   +d   l+++G+++gt+k+WD+ +g 
   Q: 514  TCATIDDsgFLFATGAYNGTVKLWDFGSGQ 543
           455553333568*************87765 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvhtlkg 92
            + +vi+c+   p+ +ll+t+s+ g i+v++ ++     +   +++ +t +++  +   ++ + + rti vwd++    + +   ++k 
   Q: 129  RRRDVIKCIVKVPQLDLLITASQKGLITVFNSQMRVQTNTSVTDTSWITGCDYLGQL-KRIVATTERTIIVWDYKaqgsSQEHYFVIKP 216
           567899999999**********************9999999999999*******998.68999999********998887788888899 PP
   S: 93   hedsvlslsfsp.....sgdklvsGshdrtirvwdletgqclee.....................tlsghdgvvncvvvhpdgnllvsG 155
            ++ +l++ + p      +d ++ G++   +  + ++++    +                       + h+++v+ +++ p  n++ s+
   Q: 217  MDHCLLCVCVVPladqlCRDDILLGDDGGFVTRFTVNSDDFGLKqaktkkklqtqvldsknfksiKRKLHNDWVMKIRFVPALNCFGSC 305
           99*****99999987655699**********99777666655555666677999**********77788************99****** PP
   S: 156  slDrtvrlWdl.....ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlv 238
           slD++  l        + +  +r++  +  +  +s  +  + + +v+g++d+ ++lw    +++ v +l gh   ++ +   +++++++
   Q: 306  SLDSVHSLVLEslkriEDNLPVREF--AMPRGANSFCYCLKANVIVTGGDDKVLRLWHPNiSTKPVGKLVGHMFSITEIVNNEKEQHVI 392
           ***9877653344444555555555..35666666666666678*************99988899************************ PP
   S: 239  sgssDgsiriWdlrsgdllktlqlhn....ssvisvavlsfgdnvlvlgsedskvniwkl 294
           s ss ++ r+Wd+++  +l+++  ++    +  i+  v++ ++ +l++gs+   + ++ l
   Q: 393  SLSSAKVFRVWDIQTLSVLQVFHDSQggpgDMQIYAMVYDTNHGMLITGSS--VIDMYPL 450
           **************************9998777777778889999999987..5666666 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDARDEKRFN LALQINNFKA SLVDFNKLVE QTTAQKKEER AGLFIPKEDA IDYDKFYASV 60
QQIFGPEVKN QDVKCFYRKL CNNPDAAFDW CEIFGYFSTD EDPLASQMDE ENMVFLVSRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTATGAAATG CAGCAGGCCT CAGCTTTCCT CCTGCTAACC CTCCTAGGAA CAGCTCTTAC 60
TCCTTGTTCC TATCAGACGG GGATAAAAAA AAACCAGAGG AATGAGACCT AGGGCAAACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

KEGG

rno:689524

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001243	Ailuropoda melanoleuca	76.67	0.00e+00	1731.00
IUUC-Apl-003630	Anas platyrhynchos	50.00	3.00e-94	339.00
IUUC-Aca-005117	Anolis carolinensis	54.51	6.00e-93	334.00
IUUC-Bta-013033	Bos taurus	79.67	0.00e+00	1792.00
IUUC-Cja-019126	Callithrix jacchus	76.90	0.00e+00	1724.00
IUUC-Cfa-020151	Canis familiaris	81.61	0.00e+00	1082.00
IUUC-Csa-023945	Chlorocebus sabaeus	79.21	0.00e+00	1771.00
IUUC-Dno-029342	Dasypus novemcinctus	74.45	0.00e+00	1688.00
IUUC-Dor-030882	Dipodomys ordii	70.25	0.00e+00	917.00
IUUC-Ete-032995	Echinops telfairi	64.46	0.00e+00	639.00
IUUC-Eca-033883	Equus caballus	80.42	0.00e+00	1836.00
IUUC-Eeu-035145	Erinaceus europaeus	60.95	0.00e+00	845.00
IUUC-Fca-036002	Felis catus	81.07	0.00e+00	1379.00
IUUC-Fal-037351	Ficedula albicollis	47.46	0.00e+00	883.00
IUUC-Gga-041212	Gallus gallus	47.25	0.00e+00	900.00
IUUC-Ggo-045447	Gorilla gorilla	74.47	0.00e+00	663.00
IUUC-Hsa-046175	Homo sapiens	79.30	0.00e+00	1775.00
IUUC-Itr-049002	Ictidomys tridecemlineatus	66.16	0.00e+00	1362.00
IUUC-Lch-050538	Latimeria chalumnae	42.16	0.00e+00	635.00
IUUC-Laf-053922	Loxodonta africana	78.36	0.00e+00	1749.00
IUUC-Mcc-055613	Macaca mulatta	79.58	0.00e+00	1777.00
IUUC-Meu-056669	Macropus eugenii	54.96	0.00e+00	825.00
IUUC-Mga-060077	Meleagris gallopavo	44.22	0.00e+00	803.00
IUUC-Mmr-060964	Microcebus murinus	78.30	0.00e+00	1728.00
IUUC-Mdo-062706	Monodelphis domestica	66.18	0.00e+00	1527.00
IUUC-Mmu-063879	Mus musculus	89.42	0.00e+00	1988.00
IUUC-Mpu-066204	Mustela putorius furo	79.56	0.00e+00	1737.00
IUUC-Mlu-067032	Myotis lucifugus	77.27	0.00e+00	1713.00
IUUC-Nle-069892	Nomascus leucogenys	78.75	0.00e+00	1761.00
IUUC-Opr-070895	Ochotona princeps	71.22	0.00e+00	1305.00
IUUC-Oan-072990	Ornithorhynchus anatinus	70.93	0.00e+00	1009.00
IUUC-Ocu-074260	Oryctolagus cuniculus	75.19	0.00e+00	1636.00
IUUC-Oga-087946	Otolemur garnettii	78.06	0.00e+00	1756.00
IUUC-Oar-090249	Ovis aries	80.04	0.00e+00	1807.00
IUUC-Ptr-090673	Pan troglodytes	79.01	0.00e+00	1762.00
IUUC-Pan-091772	Papio anubis	79.51	0.00e+00	1759.00
IUUC-Psi-094037	Pelodiscus sinensis	56.36	0.00e+00	1198.00
IUUC-Pab-097565	Pongo abelii	70.03	0.00e+00	1455.00
IUUC-Pca-100863	Procavia capensis	64.98	0.00e+00	811.00
IUUC-Pva-103108	Pteropus vampyrus	83.53	0.00e+00	1003.00
IUUC-Sha-106796	Sarcophilus harrisii	66.80	0.00e+00	1062.00
IUUC-Sar-113154	Sorex araneus	58.57	3.00e-171	595.00
IUUC-Ssc-116065	Sus scrofa	87.81	5.00e-139	486.00
IUUC-Tsy-118831	Tarsius syrichta	74.98	0.00e+00	1605.00
IUUC-Tbe-127575	Tupaia belangeri	83.33	2.00e-140	493.00
IUUC-Ttr-128737	Tursiops truncatus	72.87	0.00e+00	1591.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence