iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004874

Ensembl Protein ID

ENSACAP00000006030.2

UniProt Accession

G1KF27; G1KF27_ANOCA

Protein Name

Inhibitor of growth protein

Gene Name

ing1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006183.2	ENSACAT00000006164.2	ENSACAP00000006030.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.00e-09	36.5	212	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 212  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 259
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MLNPANGGEQ LHLANYVEDY MDSIESLPFD LQRNVSLMRE IDAKYQEILK ELDDYYEKFK 60
RETDAVQKRR VLHCIQRSLI RSQELGDEKI QIVSQMVELV ENRTRQLDSH GELFETCQET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAACC CTGCAAACGG TGGGGAGCAG CTCCATTTGG CCAACTATGT GGAAGATTAC 60
ATGGACTCCA TCGAATCCCT GCCCTTCGAT CTGCAGAGAA ACGTCTCCCT GATGAGGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	92.86	2.00e-127	447.00
IUUC-Apl-003910	Anas platyrhynchos	95.34	1.00e-130	458.00
IUUC-Ame-011262	Astyanax mexicanus	66.67	5.00e-96	343.00
IUUC-Bta-013507	Bos taurus	88.03	9.00e-92	328.00
IUUC-Cja-018925	Callithrix jacchus	88.57	2.00e-120	424.00
IUUC-Cfa-020947	Canis familiaris	92.86	7.00e-127	446.00
IUUC-Cpo-022286	Cavia porcellus	90.68	7.00e-99	353.00
IUUC-Csa-023825	Chlorocebus sabaeus	88.21	8.00e-120	422.00
IUUC-Cho-024577	Choloepus hoffmanni	93.56	1.00e-100	358.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	3.00e-16	79.00
IUUC-Dno-029834	Dasypus novemcinctus	93.57	5.00e-128	449.00
IUUC-Dor-030315	Dipodomys ordii	89.74	3.00e-109	388.00
IUUC-Ete-032408	Echinops telfairi	90.64	6.00e-96	343.00
IUUC-Eca-034244	Equus caballus	93.16	3.00e-102	363.00
IUUC-Fca-035391	Felis catus	87.64	2.00e-108	384.00
IUUC-Fal-036838	Ficedula albicollis	94.64	3.00e-130	457.00
IUUC-Gga-040619	Gallus gallus	94.64	5.00e-130	456.00
IUUC-Gac-041996	Gasterosteus aculeatus	62.90	6.00e-96	343.00
IUUC-Ggo-045481	Gorilla gorilla	86.44	3.00e-95	341.00
IUUC-Hsa-046170	Homo sapiens	86.44	2.00e-95	342.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	95.73	4.00e-104	370.00
IUUC-Lch-050397	Latimeria chalumnae	89.29	1.00e-124	438.00
IUUC-Loc-052038	Lepisosteus oculatus	79.46	3.00e-99	354.00
IUUC-Laf-054126	Loxodonta africana	93.93	1.00e-128	451.00
IUUC-Mcc-055031	Macaca mulatta	86.81	6.00e-95	340.00
IUUC-Meu-056248	Macropus eugenii	94.54	7.00e-106	376.00
IUUC-Mga-059217	Meleagris gallopavo	95.28	3.00e-104	370.00
IUUC-Mmr-061581	Microcebus murinus	93.83	2.00e-107	380.00
IUUC-Mdo-062452	Monodelphis domestica	95.36	3.00e-131	460.00
IUUC-Mmu-063412	Mus musculus	91.43	1.00e-124	438.00
IUUC-Mpu-066479	Mustela putorius furo	93.59	2.00e-102	365.00
IUUC-Mlu-067586	Myotis lucifugus	78.72	1.00e-115	408.00
IUUC-Nle-069122	Nomascus leucogenys	87.86	3.00e-119	420.00
IUUC-Opr-070835	Ochotona princeps	83.26	3.00e-83	300.00
IUUC-Oan-073023	Ornithorhynchus anatinus	92.14	1.00e-123	435.00
IUUC-Ocu-073779	Oryctolagus cuniculus	87.50	1.00e-93	335.00
IUUC-Ola-086891	Oryzias latipes	64.64	2.00e-96	345.00
IUUC-Oga-087954	Otolemur garnettii	91.07	2.00e-124	438.00
IUUC-Oar-090006	Ovis aries	88.21	2.00e-120	424.00
IUUC-Ptr-090589	Pan troglodytes	88.21	6.00e-120	422.00
IUUC-Pan-091896	Papio anubis	86.81	5.00e-95	341.00
IUUC-Psi-093266	Pelodiscus sinensis	95.71	9.00e-132	462.00
IUUC-Pma-094265	Petromyzon marinus	75.34	9.00e-34	135.00
IUUC-Pab-098253	Pongo abelii	88.21	9.00e-120	422.00
IUUC-Pva-102753	Pteropus vampyrus	83.01	1.00e-91	329.00
IUUC-Rno-105964	Rattus norvegicus	91.45	8.00e-91	325.00
IUUC-Sha-107270	Sarcophilus harrisii	94.29	2.00e-129	454.00
IUUC-Tgu-116822	Taeniopygia guttata	94.64	3.00e-130	457.00
IUUC-Tni-119980	Tetraodon nigroviridis	59.61	4.00e-84	304.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	90.50
IUUC-Tvi-122341	Trichoderma virens	62.50	4.00e-16	77.00
IUUC-Ttr-128672	Tursiops truncatus	90.64	3.00e-99	353.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence