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Tag Content
UUCD2 ID IUUC-Mlu-067450
UUCD1 version UUC-MyL-00128
Ensembl Protein ID ENSMLUP00000002331.2
UniProt Accession G1NY57; G1NY57_MYOLU
Genbank Protein ID ENSMLUP00000002331
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAPE02044172
Gene Name CUL4A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000002556.2 ENSMLUT00000002564.2 ENSMLUP00000002331.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 3.90e-200 666.7 67 665
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 1    klreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkif 87
           kl+eavk+i+ ++s+++++eely+av+nlc++kv+  lYk+l++v+e+++ +q+ +   +s d+  +Lk++n++W+++++q+ ++r+if
   Q: 67   KLHEAVKAIQGSTSIRYNLEELYQAVENLCSHKVSPTLYKQLRQVCEDHVqAQILQVCTDSLDSVlFLKKINTCWQDHCRQMIMIRSIF 155
           5899**********************************************99************************************* PP
   S: 88   ayldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfle 174
           ++ldrtyv +++++ ++++++l+l+r++i++d  +++++++ +l lie+eR+geavdr+ll+++ ++l++L     ++yk+sFE kfle
   Q: 156  LFLDRTYVLQNSMLPSIWDMGLELFRNHIISDkmVQSKTIDGILLLIEQERNGEAVDRSLLRSLLSMLSDL-----QVYKDSFELKFLE 239
           *******************************************************************9998.....9************ PP
   S: 175  atqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLl 262
           +t+ +y+ae ++++qe+ev eYl++v +rl+ee +r+ +yl++st+++L+++vek+l+ +hl+++l ++l++ll++++  dl++my+L+
   Q: 240  ETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILqKGLDHLLDENRVPDLTQMYQLF 328
           ****************************************************************9989********************* PP
   S: 263  srvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvse..aFnndakFlkaldkafetfvnknsvlkaaksp 349
           srv+ g + ll++++++ik+ g+++++++ek+kd   +V+ l+   + +++l+++  ++++d +F++  +  f   + k       +  
   Q: 329  SRVKGGQQILLQHWSEYIKTFGTTIVINPEKDKD---MVKLLMLGEEFVSHLIRNevCLHKDDTFINLQKLKFFFYLEKI-----EHIT 409
           **********************************...***9999999999*9986559*********9887776666666.....3433 PP
   S: 350  .EllA.ryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLer 436
             +++ +++D++Lr+++k++t+eele++ldk++++f++i++kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecga+ftskLe+
   Q: 410  nDYFStKHVDSKLRAGNKEATDEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEG 498
           3666549********************************************************************************** PP
   S: 437  MfqdlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkae 525
           Mf+d+++S+d++++Fk+ ++n+++  s++l+v++L++g+Wpt++ +e v+L++e+ k++e f++fYl khsgRkLqWq+tlg+a lkae
   Q: 499  MFKDMELSKDIMIHFKQYMQNQSDPGSIDLTVNILTMGYWPTYTPME-VHLTPEMIKLQEVFKTFYLGKHSGRKLQWQTTLGHAVLKAE 586
           *******************************************9999.***************************************** PP
   S: 526  lkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           +k+gk+e+qVs fQ++vLL+fn+ + +s+e++k+at+++++eLrrtlqsL+++k++vl k+p++ke+e++d+f++N +f
   Q: 587  FKEGKKEFQVSLFQTLVLLMFNEGDGFSFEDIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGDF 665
           ****************************************************************************998 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
MADETPRKGN FSALVGHTNG LTKPASLAAA AVSSKPGGGG GSKKLVIKNF RDRPKLPDNY 60
TQDTWQKLHE AVKAIQGSTS IRYNLEELYQ AVENLCSHKV SPTLYKQLRQ VCEDHVQAQI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067450|E3,Cullin|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCCGACG AGACCCCCAG GAAGGGCAAC TTCTCGGCGC TCGTGGGGCA CACCAATGGC 60
CTCACCAAGC CAGCGTCCCT GGCCGCGGCC GCCGTCTCCT CCAAGCCAGG GGGCGGCGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067450|E3,Cullin|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0030097--P:hemopoiesis
GO:0001701--P:in utero embryonic development
GO:0030853--P:negative regulation of granulocyte differentiation
GO:0008284--P:positive regulation of cell proliferation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:2000001--P:regulation of DNA damage checkpoint
GO:2000819--P:regulation of nucleotide-excision repair
GO:0051246--P:regulation of protein metabolic process
GO:0035019--P:somatic stem cell population maintenance
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001592 Ailuropoda melanoleuca 91.12 0.00e+00 1315.00
IUUC-Bta-012355 Bos taurus 89.63 0.00e+00 1302.00
IUUC-Cja-019861 Callithrix jacchus 90.13 0.00e+00 1299.00
IUUC-Cfa-021009 Canis familiaris 92.41 0.00e+00 1363.00
IUUC-Cpo-021867 Cavia porcellus 89.01 0.00e+00 1346.00
IUUC-Csa-024139 Chlorocebus sabaeus 89.53 0.00e+00 1324.00
IUUC-Cho-024899 Choloepus hoffmanni 91.91 0.00e+00 944.00
IUUC-Dno-028879 Dasypus novemcinctus 85.25 0.00e+00 1261.00
IUUC-Dor-030698 Dipodomys ordii 88.87 0.00e+00 1307.00
IUUC-Ete-033101 Echinops telfairi 86.99 0.00e+00 1209.00
IUUC-Eca-033696 Equus caballus 90.77 0.00e+00 1305.00
IUUC-Fca-036333 Felis catus 91.46 0.00e+00 1313.00
IUUC-Gga-040358 Gallus gallus 86.40 0.00e+00 1310.00
IUUC-Hsa-045679 Homo sapiens 89.79 0.00e+00 1327.00
IUUC-Itr-048182 Ictidomys tridecemlineatus 88.77 0.00e+00 1204.00
IUUC-Laf-054100 Loxodonta africana 90.87 0.00e+00 1300.00
IUUC-Mcc-055168 Macaca mulatta 90.62 0.00e+00 1189.00
IUUC-Mga-059866 Meleagris gallopavo 89.51 0.00e+00 1275.00
IUUC-Mmr-061551 Microcebus murinus 89.14 0.00e+00 1326.00
IUUC-Mdo-062215 Monodelphis domestica 90.89 0.00e+00 1363.00
IUUC-Mmu-063402 Mus musculus 89.27 0.00e+00 1324.00
IUUC-Mpu-066383 Mustela putorius furo 91.34 0.00e+00 1312.00
IUUC-Nle-069606 Nomascus leucogenys 89.66 0.00e+00 1326.00
IUUC-Opr-070671 Ochotona princeps 85.21 8.00e-117 414.00
IUUC-Oan-073299 Ornithorhynchus anatinus 85.47 0.00e+00 1291.00
IUUC-Ocu-074731 Oryctolagus cuniculus 89.79 0.00e+00 1347.00
IUUC-Oar-089346 Ovis aries 89.46 0.00e+00 1295.00
IUUC-Ptr-091177 Pan troglodytes 89.79 0.00e+00 1327.00
IUUC-Pan-092191 Papio anubis 89.57 0.00e+00 1328.00
IUUC-Pab-097622 Pongo abelii 89.40 0.00e+00 1324.00
IUUC-Pca-100391 Procavia capensis 80.59 0.00e+00 932.00
IUUC-Rno-105829 Rattus norvegicus 88.61 0.00e+00 1334.00
IUUC-Sha-106762 Sarcophilus harrisii 91.14 0.00e+00 1262.00
IUUC-Ssc-116133 Sus scrofa 90.58 0.00e+00 1333.00
Created Date 25-Jun-2017

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