iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000009599.4	ENSXETT00000062691.1	ENSXETP00000060531.1
ENSXETG00000009599.4	ENSXETT00000021164.4	ENSXETP00000021164.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	8.10e-07	29.2	101	138

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l++lv+ G+d+e a++aL ++ + ++eaA+ey+ 
   Q: 101  NRQMLQELVNVGCDQEMAVRALKQTgSRSIEAALEYIS 138
           669*********************************86 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KPPTQGLLVG PAQETLLDPK VLQSKDGARQ 60
QQQQLRQPAK FAPYQKALRE IRYSLLPFAN ESGNAAAVEV NRQMLQELVN VGCDQEMAVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCGCTACA TTCTATCGGC GGCGGCGGCG GCGGCGGCGG CGGCGGGGAC GGGCGGAGAG 60
CGGAACCGTC TGTTGGCTTG CACCGAGCGG AACTCCGGTA AACTGACTAG AGCTGCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0060027--P:convergent extension involved in gastrulation
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0046620--P:regulation of organ growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	70.95	0.00e+00	1553.00
IUUC-Apl-003521	Anas platyrhynchos	74.27	0.00e+00	1317.00
IUUC-Aca-004995	Anolis carolinensis	72.96	0.00e+00	1569.00
IUUC-Ame-011481	Astyanax mexicanus	61.89	0.00e+00	1263.00
IUUC-Bta-012618	Bos taurus	71.56	0.00e+00	935.00
IUUC-Cel-018517	Caenorhabditis elegans	48.72	2.00e-123	436.00
IUUC-Cja-019430	Callithrix jacchus	70.38	0.00e+00	1476.00
IUUC-Cfa-020687	Canis familiaris	71.04	0.00e+00	1529.00
IUUC-Cpo-021985	Cavia porcellus	77.29	0.00e+00	976.00
IUUC-Csa-023534	Chlorocebus sabaeus	86.34	0.00e+00	884.00
IUUC-Cin-025264	Ciona intestinalis	62.06	5.00e-134	470.00
IUUC-Dre-027538	Danio rerio	61.49	0.00e+00	1263.00
IUUC-Dno-029126	Dasypus novemcinctus	71.37	0.00e+00	1556.00
IUUC-Dor-030172	Dipodomys ordii	68.12	0.00e+00	1279.00
IUUC-Dme-031656	Drosophila melanogaster	69.89	5.00e-178	618.00
IUUC-Ete-032813	Echinops telfairi	65.88	0.00e+00	832.00
IUUC-Eca-033868	Equus caballus	71.43	0.00e+00	1518.00
IUUC-Eeu-034881	Erinaceus europaeus	63.34	0.00e+00	1076.00
IUUC-Fca-036203	Felis catus	67.72	0.00e+00	1401.00
IUUC-Fal-036668	Ficedula albicollis	75.80	0.00e+00	1672.00
IUUC-Gmo-039195	Gadus morhua	83.14	0.00e+00	764.00
IUUC-Gac-041789	Gasterosteus aculeatus	61.35	0.00e+00	1181.00
IUUC-Ggo-044904	Gorilla gorilla	68.85	0.00e+00	1431.00
IUUC-Hsa-046254	Homo sapiens	70.82	0.00e+00	1464.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	69.40	0.00e+00	1268.00
IUUC-Lch-050079	Latimeria chalumnae	68.61	0.00e+00	1516.00
IUUC-Loc-052265	Lepisosteus oculatus	66.81	0.00e+00	926.00
IUUC-Laf-053806	Loxodonta africana	70.89	0.00e+00	1536.00
IUUC-Mcc-055253	Macaca mulatta	70.95	0.00e+00	1461.00
IUUC-Meu-056509	Macropus eugenii	79.56	0.00e+00	754.00
IUUC-Mga-059600	Meleagris gallopavo	76.52	0.00e+00	1706.00
IUUC-Mmr-061586	Microcebus murinus	70.16	0.00e+00	1427.00
IUUC-Mdo-062126	Monodelphis domestica	72.13	0.00e+00	1516.00
IUUC-Mmu-063164	Mus musculus	68.18	0.00e+00	1367.00
IUUC-Mpu-065992	Mustela putorius furo	70.86	0.00e+00	1553.00
IUUC-Mlu-067728	Myotis lucifugus	66.01	0.00e+00	1354.00
IUUC-Nle-069546	Nomascus leucogenys	70.99	0.00e+00	1445.00
IUUC-Opr-070872	Ochotona princeps	69.47	0.00e+00	1395.00
IUUC-Ont-072296	Oreochromis niloticus	84.96	0.00e+00	900.00
IUUC-Ocu-074068	Oryctolagus cuniculus	68.22	0.00e+00	1416.00
IUUC-Ola-086756	Oryzias latipes	59.25	0.00e+00	1200.00
IUUC-Oga-089066	Otolemur garnettii	70.97	0.00e+00	1497.00
IUUC-Oar-090416	Ovis aries	75.21	0.00e+00	922.00
IUUC-Ptr-091247	Pan troglodytes	70.91	0.00e+00	1468.00
IUUC-Pan-092438	Papio anubis	70.95	0.00e+00	1461.00
IUUC-Psi-093920	Pelodiscus sinensis	74.87	0.00e+00	1664.00
IUUC-Pfo-096334	Poecilia formosa	83.98	0.00e+00	874.00
IUUC-Pab-098452	Pongo abelii	69.68	0.00e+00	1449.00
IUUC-Pca-101081	Procavia capensis	66.07	0.00e+00	1421.00
IUUC-Ptt-103762	Puccinia triticina	37.04	4.00e-89	322.00
IUUC-Rno-105102	Rattus norvegicus	67.58	0.00e+00	1348.00
IUUC-Sha-106917	Sarcophilus harrisii	72.59	0.00e+00	1548.00
IUUC-Sar-113711	Sorex araneus	66.54	0.00e+00	1264.00
IUUC-Tgu-116553	Taeniopygia guttata	77.29	0.00e+00	1676.00
IUUC-Tru-118069	Takifugu rubripes	84.46	0.00e+00	886.00
IUUC-Tni-120617	Tetraodon nigroviridis	79.38	0.00e+00	866.00
IUUC-Ttr-129256	Tursiops truncatus	72.88	0.00e+00	972.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence