iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041353

Ensembl Protein ID

ENSGACP00000024019.1

UniProt Accession

G3Q2C0; G3Q2C0_GASAC

Protein Name

Uncharacterized protein

Gene Name

vav2; VAV2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000018179.1	ENSGACT00000024066.1	ENSGACP00000024019.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-19	68.7	679	731

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            ++ y++ a +  eL+l++Gd+v++ +k   d+gW+kg  e++g+ G fP+ +v 
   Q: 679  AIARYNFAARDMRELSLREGDIVKIYSKIGGDQGWWKG--EANGRIGWFPSTYVD 731
           5688**********************************..9************97 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

FPQVISAVSR ISHHSIAQIK GISLSPSSHT ALNEDDVYRS LEELADEHDL GEDDIYDCVP 60
CEDDGDDIYE DIIKVEVRQP MKMGMTEDDK RNCCLVEIQE TEAKYYKTLE DIEKSYMIPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCCTCAGG TAATCTCGGC TGTGTCACGG ATCTCCCACC ACAGCATCGC ACAAATCAAA 60
GGCATCAGGT ATGTGTCCCC TTCGTTACTC TCTCATTTAT CACCTGGACA GCCGACGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	76.09	0.00e+00	1124.00
IUUC-Apl-003262	Anas platyrhynchos	77.60	0.00e+00	1147.00
IUUC-Aca-004628	Anolis carolinensis	62.35	0.00e+00	835.00
IUUC-Ame-011608	Astyanax mexicanus	88.00	0.00e+00	1326.00
IUUC-Bta-013147	Bos taurus	75.93	0.00e+00	1082.00
IUUC-Bra-017317	Brassica rapa	35.09	7.60e-02	32.30
IUUC-Cja-018877	Callithrix jacchus	73.42	0.00e+00	1078.00
IUUC-Cfa-020315	Canis familiaris	80.42	0.00e+00	1069.00
IUUC-Cpo-021543	Cavia porcellus	75.34	0.00e+00	1078.00
IUUC-Csa-024204	Chlorocebus sabaeus	73.37	0.00e+00	1108.00
IUUC-Dre-028308	Danio rerio	85.24	0.00e+00	1298.00
IUUC-Dno-029584	Dasypus novemcinctus	77.83	0.00e+00	1005.00
IUUC-Dor-031014	Dipodomys ordii	67.90	0.00e+00	939.00
IUUC-Eca-033448	Equus caballus	72.49	0.00e+00	1079.00
IUUC-Eeu-035182	Erinaceus europaeus	71.58	8.00e-151	527.00
IUUC-Fca-035460	Felis catus	77.36	0.00e+00	1117.00
IUUC-Fal-036684	Ficedula albicollis	75.00	0.00e+00	1124.00
IUUC-Gmo-038816	Gadus morhua	90.00	0.00e+00	1283.00
IUUC-Gga-040999	Gallus gallus	80.51	0.00e+00	1163.00
IUUC-Ggo-044558	Gorilla gorilla	75.19	0.00e+00	1119.00
IUUC-Hsa-046208	Homo sapiens	75.06	0.00e+00	1117.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	74.93	0.00e+00	1015.00
IUUC-Loc-052827	Lepisosteus oculatus	83.29	0.00e+00	1272.00
IUUC-Laf-054009	Loxodonta africana	72.53	0.00e+00	1066.00
IUUC-Mcc-055054	Macaca mulatta	75.06	0.00e+00	1117.00
IUUC-Meu-056269	Macropus eugenii	67.93	3.00e-175	608.00
IUUC-Mga-060106	Meleagris gallopavo	77.21	0.00e+00	1140.00
IUUC-Mmr-061118	Microcebus murinus	75.07	0.00e+00	1117.00
IUUC-Mdo-062380	Monodelphis domestica	79.59	0.00e+00	1120.00
IUUC-Mmu-063135	Mus musculus	76.56	0.00e+00	1145.00
IUUC-Mpu-066135	Mustela putorius furo	79.70	0.00e+00	1163.00
IUUC-Nle-069465	Nomascus leucogenys	69.34	0.00e+00	1014.00
IUUC-Ont-071945	Oreochromis niloticus	86.42	0.00e+00	1291.00
IUUC-Oan-073384	Ornithorhynchus anatinus	75.58	0.00e+00	1040.00
IUUC-Ola-087499	Oryzias latipes	91.33	0.00e+00	1262.00
IUUC-Oga-088444	Otolemur garnettii	79.27	0.00e+00	1116.00
IUUC-Oar-089576	Ovis aries	73.87	0.00e+00	1023.00
IUUC-Ptr-090507	Pan troglodytes	76.04	0.00e+00	1123.00
IUUC-Pan-092325	Papio anubis	79.70	0.00e+00	1143.00
IUUC-Psi-094021	Pelodiscus sinensis	79.54	0.00e+00	1143.00
IUUC-Pma-094372	Petromyzon marinus	51.30	0.00e+00	679.00
IUUC-Pfo-096732	Poecilia formosa	86.89	0.00e+00	1312.00
IUUC-Pab-098426	Pongo abelii	67.38	0.00e+00	922.00
IUUC-Pca-100295	Procavia capensis	75.45	0.00e+00	1133.00
IUUC-Rno-105332	Rattus norvegicus	75.78	0.00e+00	1115.00
IUUC-Sha-106529	Sarcophilus harrisii	76.14	0.00e+00	1051.00
IUUC-Ssc-116176	Sus scrofa	74.87	0.00e+00	1118.00
IUUC-Tgu-116917	Taeniopygia guttata	77.18	0.00e+00	1142.00
IUUC-Tru-118398	Takifugu rubripes	87.60	0.00e+00	1100.00
IUUC-Tni-120819	Tetraodon nigroviridis	87.76	0.00e+00	1328.00
IUUC-Xtr-132747	Xenopus tropicalis	74.29	0.00e+00	1101.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence