iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006948

UUCD1 version

UUC-ArT-00520

Ensembl Protein ID

AT5G50230.1

UniProt Accession

Q6NNP0; Q9FGS2; ATG16_ARATH

Genbank Protein ID

BAB09394.1; AED95914.1; AAR92280.1; AAV85684.1

Protein Name

Autophagy-related protein 16

Genbank Nucleotide ID

AB024031; CP002688; BT011244; BT020329

Gene Name

ATG16; At5g50230; K6A12.9

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G50230	AT5G50230.1	AT5G50230.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-27	94.3	307	344
UBD/Beta-Prp	2.00e-49	169.3	223	435

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvl 35
           gHtd+v++++    s++++vs+++D tik+WDl++g +
   Q: 307  GHTDKVCAVDVskfSSRHVVSAAYDRTIKLWDLHKGYC 344
           8*******98888766*****************99876 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp. 104
           +h++ + ++ f  ++  l+tg++d+ +k wd+ +g+l++sl+g  + + ++   +d k  + + + +++ vwd+s+g   htl+gh+d+v+++++s+ 
   Q: 223  AHEGGCGSIVFEYNSGTLFTGGQDRAVKMWDTNSGTLIKSLYGSLGNILDMAVTHDNKSVIAATSSNNLFVWDVSSGRVRHTLTGHTDKVCAVDVSKf 320
           5677778888988889999**************************************99999999999*****************************8 PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldg 202
           s+ ++vs+  drti++wdl++g+c +++l   +    c+++++    ++sG+ D+ +rlWd++tgkll +  g h ++v+s+s+++ng+++++ ++d+
   Q: 321  SSRHVVSAAYDRTIKLWDLHKGYCTNTVLFTSNCNAICLSIDG--LTVFSGHMDGNLRLWDIQTGKLLSEVAG-HSSAVTSVSLSRNGNRILTSGRDN 415
           88************************99999997777777777..999***********************99.************************ PP
   S: 203  tvklwdlqtgecvrtlnght 222
             +++d +t e+  tl++  
   Q: 416  VHNVFDTRTLEICGTLRASG 435
           ********999999998865 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

May play a role in autophagy.

Protein Sequence
(Fasta)

MVQEEKAMEA INDALRALRK RHLLEEGAHA PAISALSKPL ISQGSEWKEK TEKLETELQQ 60
CYKAQSRLSE QLVIEVAESR TSKAILQEKE LLINDLQKEL TQRREDCTRL QEELEEKTKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAAACTGA TTATAATCAA TTTTCAATAA ACTAAATTTG TGGGGGAAAA TCCCCAATTC 60
ACTTGCAGCT TTTGTAATTT CTCTAATTTG GGTCGTAACT CGTAAGCGGC GGTGGAATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0000045--P:autophagosome assembly
GO:0015031--P:protein transport

KEGG

ath:AT5G50230

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	50.40	7.00e-140	489.00
IUUC-Aml-001470	Ailuropoda melanoleuca	30.77	5.00e-40	158.00
IUUC-Atr-003073	Amborella trichopoda	60.41	1.00e-151	529.00
IUUC-Apl-003384	Anas platyrhynchos	26.40	1.00e-46	180.00
IUUC-Aca-004962	Anolis carolinensis	34.33	2.00e-45	176.00
IUUC-Aly-005435	Arabidopsis lyrata	96.86	0.00e+00	975.00
IUUC-Ame-010915	Astyanax mexicanus	34.97	1.00e-39	156.00
IUUC-Bta-012388	Bos taurus	33.00	6.00e-46	178.00
IUUC-Bdi-014231	Brachypodium distachyon	51.65	4.00e-146	510.00
IUUC-Bol-016174	Brassica oleracea	90.96	0.00e+00	913.00
IUUC-Bra-017165	Brassica rapa	89.94	0.00e+00	919.00
IUUC-Cel-018131	Caenorhabditis elegans	29.13	2.00e-32	133.00
IUUC-Cja-020002	Callithrix jacchus	30.79	7.00e-36	144.00
IUUC-Cfa-020484	Canis familiaris	27.36	4.00e-46	178.00
IUUC-Cpo-022156	Cavia porcellus	27.50	8.00e-45	174.00
IUUC-Csa-024019	Chlorocebus sabaeus	28.96	8.00e-51	194.00
IUUC-Cho-024311	Choloepus hoffmanni	36.06	4.00e-34	139.00
IUUC-Cin-025260	Ciona intestinalis	24.56	5.00e-36	145.00
IUUC-Dre-027702	Danio rerio	35.67	6.00e-46	178.00
IUUC-Dno-029728	Dasypus novemcinctus	34.65	3.00e-46	179.00
IUUC-Dor-030897	Dipodomys ordii	30.69	3.00e-40	159.00
IUUC-Dme-031595	Drosophila melanogaster	30.82	2.00e-35	143.00
IUUC-Ete-032969	Echinops telfairi	34.14	8.00e-44	171.00
IUUC-Eca-034214	Equus caballus	35.16	1.00e-43	169.00
IUUC-Eeu-034537	Erinaceus europaeus	31.68	5.00e-37	148.00
IUUC-Fca-036005	Felis catus	34.65	6.00e-46	177.00
IUUC-Fal-037593	Ficedula albicollis	34.32	2.00e-46	179.00
IUUC-Gmo-039042	Gadus morhua	31.72	8.00e-34	137.00
IUUC-Gga-040986	Gallus gallus	34.98	9.00e-48	184.00
IUUC-Gac-041351	Gasterosteus aculeatus	35.53	5.00e-48	185.00
IUUC-Gma-043265	Glycine max	73.37	0.00e+00	805.00
IUUC-Ggo-045427	Gorilla gorilla	35.10	2.00e-46	179.00
IUUC-Hsa-046632	Homo sapiens	35.10	2.00e-46	179.00
IUUC-Hvu-047655	Hordeum vulgare	51.85	8.00e-117	412.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	29.24	5.00e-51	194.00
IUUC-Lpe-051254	Leersia perrieri	52.83	1.00e-145	509.00
IUUC-Loc-052610	Lepisosteus oculatus	35.20	2.00e-47	183.00
IUUC-Laf-053936	Loxodonta africana	33.67	3.00e-45	176.00
IUUC-Mcc-055504	Macaca mulatta	34.77	3.00e-46	179.00
IUUC-Meu-056516	Macropus eugenii	33.33	2.00e-45	176.00
IUUC-Mtr-058062	Medicago truncatula	70.81	0.00e+00	756.00
IUUC-Mla-059081	Melampsora laricipopulina	31.15	4.00e-28	119.00
IUUC-Mga-059777	Meleagris gallopavo	26.49	1.00e-45	177.00
IUUC-Mmr-061298	Microcebus murinus	35.10	7.00e-47	181.00
IUUC-Mdo-062969	Monodelphis domestica	33.99	7.00e-46	177.00
IUUC-Mmu-064076	Mus musculus	34.78	1.00e-46	180.00
IUUC-Mac-065161	Musa acuminata	62.16	6.00e-177	612.00
IUUC-Mpu-066196	Mustela putorius furo	34.32	6.00e-46	178.00
IUUC-Mlu-067651	Myotis lucifugus	28.08	2.00e-46	179.00
IUUC-Nle-069853	Nomascus leucogenys	33.44	1.00e-43	170.00
IUUC-Opr-071039	Ochotona princeps	31.02	1.00e-40	160.00
IUUC-Ont-072489	Oreochromis niloticus	34.98	1.00e-47	183.00
IUUC-Oan-072703	Ornithorhynchus anatinus	34.75	3.00e-46	179.00
IUUC-Ocu-074205	Oryctolagus cuniculus	34.77	9.00e-46	177.00
IUUC-Oba-075619	Oryza barthii	53.41	2.00e-152	531.00
IUUC-Obr-076632	Oryza brachyantha	52.24	4.00e-141	494.00
IUUC-Ogl-077671	Oryza glaberrima	53.41	2.00e-152	531.00
IUUC-Ogu-078052	Oryza glumaepatula	53.61	7.00e-153	533.00
IUUC-Oin-079611	Oryza indica	53.61	3.00e-151	527.00
IUUC-Olo-080408	Oryza longistaminata	53.80	1.00e-140	492.00
IUUC-Ome-081560	Oryza meridionalis	53.61	6.00e-153	533.00
IUUC-Oni-082145	Oryza nivara	53.41	2.00e-152	531.00
IUUC-Opu-083918	Oryza punctata	53.41	5.00e-140	490.00
IUUC-Oru-084858	Oryza rufipogon	53.61	1.00e-150	525.00
IUUC-Osa-086277	Oryza sativa	53.61	3.00e-151	527.00
IUUC-Ola-086964	Oryzias latipes	36.18	9.00e-43	166.00
IUUC-Olu-087622	Ostreococcus lucimarinus	33.06	7.00e-65	240.00
IUUC-Oga-088765	Otolemur garnettii	29.00	5.00e-52	198.00
IUUC-Oar-090196	Ovis aries	33.57	2.00e-43	169.00
IUUC-Ptr-091676	Pan troglodytes	35.10	2.00e-46	179.00
IUUC-Pan-092068	Papio anubis	34.77	3.00e-46	179.00
IUUC-Psi-093367	Pelodiscus sinensis	34.98	7.00e-49	187.00
IUUC-Ppa-095699	Physcomitrella patens	49.31	1.00e-138	486.00
IUUC-Pfo-096067	Poecilia formosa	28.46	4.00e-48	185.00
IUUC-Pab-098111	Pongo abelii	35.10	4.00e-46	178.00
IUUC-Pop-099116	Populus trichocarpa	73.48	0.00e+00	800.00
IUUC-Pca-100680	Procavia capensis	34.70	8.00e-35	140.00
IUUC-Ppe-101790	Prunus persica	72.92	0.00e+00	799.00
IUUC-Pva-102871	Pteropus vampyrus	34.32	3.00e-47	182.00
IUUC-Pgr-103597	Puccinia graminis	30.83	8.00e-28	119.00
IUUC-Rno-106088	Rattus norvegicus	34.78	9.00e-47	181.00
IUUC-Sha-106984	Sarcophilus harrisii	26.40	5.00e-48	184.00
IUUC-Smo-108983	Selaginella moellendorffii	47.95	2.00e-135	475.00
IUUC-Sit-110828	Setaria italica	54.10	4.00e-152	530.00
IUUC-Sly-111009	Solanum lycopersicum	70.23	0.00e+00	721.00
IUUC-Stu-112370	Solanum tuberosum	70.14	0.00e+00	778.00
IUUC-Sar-113109	Sorex araneus	34.93	1.00e-26	114.00
IUUC-Sbi-114819	Sorghum bicolor	53.28	3.00e-149	520.00
IUUC-Ssc-116241	Sus scrofa	35.47	3.00e-43	169.00
IUUC-Tgu-116576	Taeniopygia guttata	34.44	4.00e-46	178.00
IUUC-Tru-118336	Takifugu rubripes	31.68	8.00e-35	141.00
IUUC-Tsy-119006	Tarsius syrichta	34.77	3.00e-46	179.00
IUUC-Tni-120300	Tetraodon nigroviridis	34.87	5.00e-46	178.00
IUUC-Tca-121002	Theobroma cacao	71.51	0.00e+00	776.00
IUUC-Tae-124868	Triticum aestivum	50.81	1.00e-140	492.00
IUUC-Tur-126463	Triticum urartu	50.00	1.00e-139	489.00
IUUC-Tbe-127631	Tupaia belangeri	35.43	2.00e-46	179.00
IUUC-Ttr-129005	Tursiops truncatus	34.54	5.00e-38	152.00
IUUC-Vvi-130878	Vitis vinifera	69.16	0.00e+00	754.00
IUUC-Xtr-132798	Xenopus tropicalis	27.34	3.00e-37	149.00
IUUC-Xma-133264	Xiphophorus maculatus	29.48	3.00e-48	185.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence