iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091957

Ensembl Protein ID

ENSPANP00000004245.1

UniProt Accession

A0A096MWI9; A0A096MWI9_PAPAN

Genbank Protein ID

ENSPANP00000004245

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01029789

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000025375.1	ENSPANT00000000126.1	ENSPANP00000004245.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-69	235.3	942	1287

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 942  VGLTNLGATCYLASTIQQLYMIPEARQAVFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1021
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1022 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 1080
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 1081 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 1162
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                + +k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 1163 MTPYTEDflmgkserkegfkevnDHSKDSESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 1249
           *******99999999999999986666667***************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 1250 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 1287
           7779********************************96 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MMKLFFDNLV YYIQTVREGR QKHALYSHSA EVQVRLQFLT CVFSTLGSPD HFRLSLEQVD 60
ILWHCLVEDS ECYDDALHWF LNQVRSKDQH AMGMETYKHL FLEKMPQLKP ETISMTGLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGAAGC TTTTCTTTGA TAATTTGGTA TACTACATTC AAACTGTGAG AGAAGGAAGA 60
CAAAAACATG CACTGTAAGT ACCTCTCAAC TGAGTTAAAT ACATTTGTGT GGATTGTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	98.92	0.00e+00	5133.00
IUUC-Apl-003284	Anas platyrhynchos	95.77	0.00e+00	4991.00
IUUC-Aca-004415	Anolis carolinensis	94.27	0.00e+00	4893.00
IUUC-Acl-008140	Aspergillus clavatus	28.45	1.00e-63	239.00
IUUC-Afl-008381	Aspergillus flavus	27.09	2.00e-63	239.00
IUUC-Afu-008857	Aspergillus fumigatus	26.70	3.00e-63	238.00
IUUC-Ani-009257	Aspergillus nidulans	28.49	9.00e-56	213.00
IUUC-Ang-009759	Aspergillus niger	27.57	2.00e-63	238.00
IUUC-Aor-009931	Aspergillus oryzae	28.64	2.00e-63	239.00
IUUC-Ate-010246	Aspergillus terreus	29.03	2.00e-52	202.00
IUUC-Ame-011219	Astyanax mexicanus	64.77	0.00e+00	2477.00
IUUC-Bgr-012195	Blumeria graminis	27.80	2.00e-64	242.00
IUUC-Bta-012989	Bos taurus	98.73	0.00e+00	5079.00
IUUC-Bci-013798	Botrytis cinerea	32.44	6.00e-58	220.00
IUUC-Cja-018974	Callithrix jacchus	97.88	0.00e+00	831.00
IUUC-Cfa-021214	Canis familiaris	99.00	0.00e+00	5140.00
IUUC-Cpo-021912	Cavia porcellus	99.02	0.00e+00	3053.00
IUUC-Csa-023658	Chlorocebus sabaeus	99.85	0.00e+00	5174.00
IUUC-Cho-024971	Choloepus hoffmanni	83.80	0.00e+00	3204.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	27.68	3.00e-63	238.00
IUUC-Dre-027428	Danio rerio	84.29	0.00e+00	4288.00
IUUC-Dno-029690	Dasypus novemcinctus	98.04	0.00e+00	5059.00
IUUC-Dor-030817	Dipodomys ordii	88.85	0.00e+00	2156.00
IUUC-Dse-031423	Dothistroma septosporum	25.23	2.00e-35	146.00
IUUC-Dme-032102	Drosophila melanogaster	54.00	0.00e+00	847.00
IUUC-Ete-032552	Echinops telfairi	93.93	0.00e+00	3002.00
IUUC-Eca-033457	Equus caballus	98.61	0.00e+00	5104.00
IUUC-Eeu-035118	Erinaceus europaeus	94.14	0.00e+00	3074.00
IUUC-Fca-036213	Felis catus	96.23	0.00e+00	4989.00
IUUC-Fal-037643	Ficedula albicollis	93.05	0.00e+00	4861.00
IUUC-Fox-037971	Fusarium oxysporum	26.95	9.00e-63	236.00
IUUC-Fso-038108	Fusarium solani	26.78	2.00e-59	225.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.39	2.00e-62	235.00
IUUC-Gga-040511	Gallus gallus	93.20	0.00e+00	4906.00
IUUC-Gac-042024	Gasterosteus aculeatus	91.61	0.00e+00	3903.00
IUUC-Ggo-044924	Gorilla gorilla	94.58	0.00e+00	4928.00
IUUC-Hsa-046913	Homo sapiens	99.58	0.00e+00	5163.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	99.11	0.00e+00	5141.00
IUUC-Lch-049675	Latimeria chalumnae	86.77	0.00e+00	3406.00
IUUC-Loc-052832	Lepisosteus oculatus	89.06	0.00e+00	4589.00
IUUC-Lma-053130	Leptosphaeria maculans	27.32	6.00e-61	230.00
IUUC-Laf-054169	Loxodonta africana	97.49	0.00e+00	5092.00
IUUC-Mcc-055847	Macaca mulatta	98.65	0.00e+00	5087.00
IUUC-Meu-056327	Macropus eugenii	85.38	0.00e+00	1564.00
IUUC-Mor-057152	Magnaporthe oryzae	35.14	1.00e-61	233.00
IUUC-Mpo-057310	Magnaporthe poae	26.73	3.00e-60	228.00
IUUC-Mmr-060780	Microcebus murinus	98.96	0.00e+00	5135.00
IUUC-Mdo-062308	Monodelphis domestica	95.07	0.00e+00	4977.00
IUUC-Mmu-063457	Mus musculus	98.07	0.00e+00	5073.00
IUUC-Mpu-066917	Mustela putorius furo	95.73	0.00e+00	4909.00
IUUC-Mlu-067696	Myotis lucifugus	98.50	0.00e+00	5103.00
IUUC-Nfi-068259	Neosartorya fischeri	27.05	8.00e-64	240.00
IUUC-Ncr-068911	Neurospora crassa	26.19	3.00e-59	225.00
IUUC-Nle-069586	Nomascus leucogenys	99.46	0.00e+00	5156.00
IUUC-Opr-070447	Ochotona princeps	93.93	0.00e+00	2888.00
IUUC-Ont-072396	Oreochromis niloticus	88.60	0.00e+00	4296.00
IUUC-Oan-073147	Ornithorhynchus anatinus	95.65	0.00e+00	4999.00
IUUC-Ocu-074324	Oryctolagus cuniculus	98.54	0.00e+00	5108.00
IUUC-Ola-086312	Oryzias latipes	87.04	0.00e+00	4328.00
IUUC-Oga-088878	Otolemur garnettii	98.84	0.00e+00	5143.00
IUUC-Oar-089919	Ovis aries	98.73	0.00e+00	5075.00
IUUC-Ptr-090713	Pan troglodytes	99.31	0.00e+00	4582.00
IUUC-Psi-093240	Pelodiscus sinensis	95.00	0.00e+00	4963.00
IUUC-Pma-094469	Petromyzon marinus	73.24	0.00e+00	3811.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.57	2.00e-57	218.00
IUUC-Pfo-097159	Poecilia formosa	87.15	0.00e+00	4326.00
IUUC-Pab-098003	Pongo abelii	99.34	0.00e+00	5147.00
IUUC-Pca-100799	Procavia capensis	90.99	0.00e+00	1941.00
IUUC-Pva-103226	Pteropus vampyrus	93.53	0.00e+00	4797.00
IUUC-Pte-104235	Pyrenophora teres	26.71	6.00e-59	224.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.20	8.00e-61	229.00
IUUC-Rno-105389	Rattus norvegicus	96.99	0.00e+00	5033.00
IUUC-Sha-106979	Sarcophilus harrisii	95.73	0.00e+00	4975.00
IUUC-Sar-113444	Sorex araneus	89.71	0.00e+00	4543.00
IUUC-Ssc-115815	Sus scrofa	98.52	0.00e+00	3953.00
IUUC-Tgu-117470	Taeniopygia guttata	95.39	0.00e+00	4958.00
IUUC-Tru-118543	Takifugu rubripes	83.49	0.00e+00	4288.00
IUUC-Tsy-119081	Tarsius syrichta	89.55	0.00e+00	4566.00
IUUC-Tre-122057	Trichoderma reesei	29.56	2.00e-62	235.00
IUUC-Tvi-122570	Trichoderma virens	35.89	1.00e-59	226.00
IUUC-Tme-127154	Tuber melanosporum	27.52	4.00e-60	226.00
IUUC-Tbe-127801	Tupaia belangeri	86.81	0.00e+00	3321.00
IUUC-Ttr-129262	Tursiops truncatus	93.91	0.00e+00	4827.00
IUUC-Vda-129686	Verticillium dahliae	28.06	1.00e-62	236.00
IUUC-Vpa-130484	Vicugna pacos	95.76	0.00e+00	4923.00
IUUC-Xtr-131769	Xenopus tropicalis	87.68	0.00e+00	4603.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence