iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-002821

Ensembl Protein ID

ERN00443

UniProt Accession

W1NXR4; W1NXR4_AMBTC

Genbank Protein ID

ERN00443.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

KI394904

Gene Name

AMTR_s00100p00119160

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00100p00119160	ERN00443	ERN00443

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.60e-100	336.1	1459	1870

Active Site

Position(s)	Description	Evidence
1838	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysen.dketlqpnpdsglknp.................................. 65
           +s++k++leve+ gE g++l G+t+ef++lls++lq+  l++++ s++ +k+ ++++ +  + ++                                  
   Q: 1459 YSSQKAVLEVEYFGEVGTGL-GPTLEFYTLLSHDLQKICLEMWRSSSSpEKSVMEIDGQDQTVENmddvtatkklvldpvggelvqaplglfprpwppn 1556
           578999**************.**********************999998888888887666544579******************************** PP
   S: 66   ..........ehlklFeflGrllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaes.......................d 131
                     ++ ++F+++Gr+++kalqdgrlldlpls++f+kl+lg +l+l+d+ ++d+++ k l+e++ ++++                        
   Q: 1557 adtsegskfsKVVEYFRLVGRVMAKALQDGRLLDLPLSPAFFKLVLGYELDLHDILSFDADFGKILQEMQVLVHKkeylesmpgdhrelisdlrfrgaP 1655
           **********************************************************************99944455666777555444444444334 PP
   S: 132  ieelgldltfsvseei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eei 224
           ie+            +     l+ ++++ Lk+g e+++V + N++eY+ lvv++++++gi +q+eafr+Gfn+v+++++l++Ft+ el++l+cG+ e +
   Q: 1656 IED------------LcldftLPGYSDYILKEGAESTMVDIHNLDEYITLVVDATVRTGIMRQMEAFRAGFNQVFDITSLQIFTPTELDYLLCGRrELW 1742
           444............344444899***********************************************************************999* PP
   S: 225  dvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk................dasddrlPssnTCfny 307
           + e+l++++k+++gyt++spai +++e++ ef+ e+++af+qFvTg +rlP+gG+a l+p+l+++rk                +++d++lPs++TC+ny
   Q: 1743 EPETLADHIKFDHGYTAKSPAITNLLEIMGEFTPEQQRAFCQFVTGAPRLPPGGLAVLNPKLTIVRKhsssstnissngtgvtESADEDLPSVMTCANY 1841
           **********************************************************************************99999************ PP
   S: 308  LkLPeYsskeilkekLlyAieet.kgFel 335
           LkLP+Ys+kei+ +kLlyA++e+  +F+l
   Q: 1842 LKLPPYSTKEIMLKKLLYAVSEGqGSFDL 1870
           ***********************889987 PP

Organism

Amborella trichopoda

Protein Sequence
(Fasta)

METRSRKRAE ASSSALSHST RSSKKPRLSS SCTTTPSPRT RPLNSRTTPL NSRTTPPTTD 60
KMDDSSSAST SRKLRNSQKQ EKDSSDKGKE KEPETNRHHT SNLSTDGVAG DDDHESSEGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAACGC GGAGCCGCAA GCGGGCGGAG GCCTCCTCAT CAGCCCTTTC TCACTCCACT 60
CGTTCCTCTA AGAAACCCCG CCTCTCATCC TCCTGCACAA CCACCCCTTC TCCACGCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0005886--C:plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0042023--P:DNA endoreduplication
GO:0010091--P:trichome branching

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	64.36	0.00e+00	2001.00
IUUC-Aml-001502	Ailuropoda melanoleuca	37.48	7.00e-116	411.00
IUUC-Apl-003531	Anas platyrhynchos	41.65	5.00e-104	372.00
IUUC-Aca-004521	Anolis carolinensis	33.77	2.00e-67	251.00
IUUC-Aly-005962	Arabidopsis lyrata	67.97	0.00e+00	1998.00
IUUC-Ath-006636	Arabidopsis thaliana	66.63	0.00e+00	1993.00
IUUC-Ago-007875	Ashbya gossypii	35.24	3.00e-84	306.00
IUUC-Acl-008242	Aspergillus clavatus	39.82	4.00e-105	375.00
IUUC-Afl-008736	Aspergillus flavus	40.47	8.00e-106	378.00
IUUC-Afu-008812	Aspergillus fumigatus	40.53	2.00e-106	380.00
IUUC-Ani-009407	Aspergillus nidulans	39.24	2.00e-101	363.00
IUUC-Ang-009763	Aspergillus niger	39.82	2.00e-99	357.00
IUUC-Aor-009941	Aspergillus oryzae	40.47	3.00e-105	376.00
IUUC-Ate-010459	Aspergillus terreus	40.55	4.00e-92	332.00
IUUC-Ame-011761	Astyanax mexicanus	43.42	2.00e-115	410.00
IUUC-Bgr-012265	Blumeria graminis	39.43	2.00e-100	360.00
IUUC-Bta-013070	Bos taurus	43.23	8.00e-115	408.00
IUUC-Bci-013890	Botrytis cinerea	39.44	6.00e-102	365.00
IUUC-Bdi-014046	Brachypodium distachyon	65.92	0.00e+00	1987.00
IUUC-Bol-015942	Brassica oleracea	66.57	0.00e+00	1988.00
IUUC-Bra-016849	Brassica rapa	66.57	0.00e+00	1989.00
IUUC-Cel-018153	Caenorhabditis elegans	35.74	1.00e-88	321.00
IUUC-Cja-019046	Callithrix jacchus	43.23	1.00e-114	407.00
IUUC-Cfa-020521	Canis familiaris	37.34	4.00e-115	409.00
IUUC-Cpo-021639	Cavia porcellus	43.23	4.00e-114	405.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	50.00	1.00e-138	485.00
IUUC-Csa-023231	Chlorocebus sabaeus	43.23	7.00e-115	408.00
IUUC-Cho-024380	Choloepus hoffmanni	42.66	2.00e-89	323.00
IUUC-Cin-025482	Ciona intestinalis	36.75	2.00e-97	348.00
IUUC-Csv-026121	Ciona savignyi	36.79	5.00e-95	342.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	39.44	2.00e-107	383.00
IUUC-Cne-026857	Cryptococcus neoformans	38.14	4.00e-90	326.00
IUUC-Cme-027226	Cyanidioschyzon merolae	35.78	8.00e-78	285.00
IUUC-Dre-028174	Danio rerio	37.05	1.00e-116	414.00
IUUC-Dno-029954	Dasypus novemcinctus	32.04	3.00e-65	244.00
IUUC-Dor-030939	Dipodomys ordii	38.35	7.00e-92	332.00
IUUC-Dse-031444	Dothistroma septosporum	39.10	1.00e-102	367.00
IUUC-Dme-031739	Drosophila melanogaster	35.32	4.00e-88	320.00
IUUC-Ete-032345	Echinops telfairi	36.09	4.00e-83	302.00
IUUC-Eca-033229	Equus caballus	43.23	1.00e-114	407.00
IUUC-Eeu-035205	Erinaceus europaeus	43.37	1.00e-112	401.00
IUUC-Fca-036444	Felis catus	43.23	1.00e-114	407.00
IUUC-Fal-037131	Ficedula albicollis	43.61	1.00e-115	411.00
IUUC-Fox-038035	Fusarium oxysporum	41.76	4.00e-109	387.00
IUUC-Fso-038320	Fusarium solani	40.52	3.00e-108	386.00
IUUC-Gmo-039497	Gadus morhua	37.68	5.00e-117	415.00
IUUC-Ggr-040057	Gaeumannomyces graminis	39.10	3.00e-104	373.00
IUUC-Gga-041021	Gallus gallus	43.61	5.00e-116	412.00
IUUC-Gac-042474	Gasterosteus aculeatus	37.87	2.00e-117	417.00
IUUC-Gma-043715	Glycine max	69.71	0.00e+00	2148.00
IUUC-Ggo-044855	Gorilla gorilla	43.23	7.00e-115	408.00
IUUC-Hsa-046147	Homo sapiens	43.23	1.00e-114	407.00
IUUC-Hvu-047775	Hordeum vulgare	66.02	0.00e+00	2023.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	43.05	2.00e-113	404.00
IUUC-Kpa-049098	Komagataella pastoris	37.74	6.00e-87	315.00
IUUC-Lch-049818	Latimeria chalumnae	36.93	6.00e-109	388.00
IUUC-Lpe-051017	Leersia perrieri	63.48	0.00e+00	1828.00
IUUC-Loc-051777	Lepisosteus oculatus	43.80	1.00e-117	417.00
IUUC-Lma-052990	Leptosphaeria maculans	40.45	2.00e-106	380.00
IUUC-Laf-053727	Loxodonta africana	43.23	1.00e-114	407.00
IUUC-Mcc-055799	Macaca mulatta	43.23	1.00e-114	407.00
IUUC-Meu-056065	Macropus eugenii	34.83	5.00e-93	335.00
IUUC-Mor-057054	Magnaporthe oryzae	39.66	4.00e-102	365.00
IUUC-Mpo-057417	Magnaporthe poae	39.85	3.00e-104	373.00
IUUC-Mtr-057849	Medicago truncatula	69.13	0.00e+00	2094.00
IUUC-Mla-058870	Melampsora laricipopulina	39.85	9.00e-92	331.00
IUUC-Mga-059580	Meleagris gallopavo	33.01	5.00e-70	259.00
IUUC-Mvi-060507	Microbotryum violaceum	39.70	5.00e-105	375.00
IUUC-Mmr-060816	Microcebus murinus	42.86	5.00e-113	402.00
IUUC-Mdo-062866	Monodelphis domestica	35.09	3.00e-94	339.00
IUUC-Mmu-063906	Mus musculus	37.34	3.00e-114	406.00
IUUC-Mac-065153	Musa acuminata	68.38	0.00e+00	1030.00
IUUC-Mpu-066199	Mustela putorius furo	37.48	1.00e-115	410.00
IUUC-Mlu-067110	Myotis lucifugus	42.67	4.00e-112	399.00
IUUC-Nfi-068482	Neosartorya fischeri	40.53	4.00e-106	379.00
IUUC-Ncr-068906	Neurospora crassa	40.38	6.00e-107	382.00
IUUC-Nle-069410	Nomascus leucogenys	43.23	9.00e-115	407.00
IUUC-Opr-070401	Ochotona princeps	40.34	8.00e-50	192.00
IUUC-Ont-072100	Oreochromis niloticus	38.01	2.00e-117	417.00
IUUC-Oan-073121	Ornithorhynchus anatinus	37.34	2.00e-115	410.00
IUUC-Ocu-074623	Oryctolagus cuniculus	43.23	1.00e-114	407.00
IUUC-Oba-074990	Oryza barthii	63.30	0.00e+00	1750.00
IUUC-Obr-076915	Oryza brachyantha	64.88	0.00e+00	1905.00
IUUC-Ogl-077055	Oryza glaberrima	62.44	0.00e+00	1781.00
IUUC-Ogu-078685	Oryza glumaepatula	63.19	0.00e+00	1755.00
IUUC-Oin-079256	Oryza indica	64.63	0.00e+00	1843.00
IUUC-Olo-080343	Oryza longistaminata	64.69	0.00e+00	1843.00
IUUC-Ome-081422	Oryza meridionalis	64.56	0.00e+00	1873.00
IUUC-Oni-082469	Oryza nivara	63.62	0.00e+00	1816.00
IUUC-Opu-083792	Oryza punctata	63.07	0.00e+00	1787.00
IUUC-Oru-084607	Oryza rufipogon	63.13	0.00e+00	1756.00
IUUC-Osa-085972	Oryza sativa	71.24	0.00e+00	965.00
IUUC-Ola-087173	Oryzias latipes	37.82	1.00e-116	414.00
IUUC-Olu-087871	Ostreococcus lucimarinus	46.93	2.00e-130	457.00
IUUC-Oga-087908	Otolemur garnettii	43.05	7.00e-114	405.00
IUUC-Oar-090277	Ovis aries	43.23	1.00e-114	407.00
IUUC-Ptr-091543	Pan troglodytes	43.23	1.00e-114	407.00
IUUC-Pan-092243	Papio anubis	43.23	9.00e-115	408.00
IUUC-Psi-093150	Pelodiscus sinensis	43.05	2.00e-114	406.00
IUUC-Pno-094891	Phaeosphaeria nodorum	40.00	9.00e-108	384.00
IUUC-Ppa-095181	Physcomitrella patens	55.92	0.00e+00	747.00
IUUC-Pfo-096267	Poecilia formosa	43.23	5.00e-116	412.00
IUUC-Pab-098072	Pongo abelii	43.23	7.00e-115	408.00
IUUC-Pop-099190	Populus trichocarpa	72.57	0.00e+00	2156.00
IUUC-Pca-100311	Procavia capensis	43.23	2.00e-114	407.00
IUUC-Ppe-101284	Prunus persica	73.14	0.00e+00	2246.00
IUUC-Pva-102215	Pteropus vampyrus	39.47	1.00e-97	351.00
IUUC-Pgr-103694	Puccinia graminis	39.66	1.00e-94	341.00
IUUC-Ptt-103916	Puccinia triticina	38.52	6.00e-88	318.00
IUUC-Pte-104346	Pyrenophora teres	38.84	4.00e-103	369.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	38.84	6.00e-103	368.00
IUUC-Rno-105315	Rattus norvegicus	37.48	4.00e-115	409.00
IUUC-Sha-106835	Sarcophilus harrisii	37.34	2.00e-114	406.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	36.21	2.00e-89	323.00
IUUC-Spo-108081	Schizosaccharomyces pombe	36.90	7.00e-86	311.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	40.37	1.00e-104	374.00
IUUC-Smo-108776	Selaginella moellendorffii	61.73	0.00e+00	810.00
IUUC-Sit-109757	Setaria italica	64.04	0.00e+00	1988.00
IUUC-Sly-111469	Solanum lycopersicum	68.20	0.00e+00	2199.00
IUUC-Stu-112896	Solanum tuberosum	68.57	0.00e+00	991.00
IUUC-Sar-113224	Sorex araneus	43.21	5.00e-83	302.00
IUUC-Sbi-114313	Sorghum bicolor	66.26	0.00e+00	2056.00
IUUC-Sre-114993	Sporisorium reilianum	37.59	2.00e-92	333.00
IUUC-Ssc-115535	Sus scrofa	39.74	6.00e-96	345.00
IUUC-Tgu-117167	Taeniopygia guttata	33.55	1.00e-65	244.00
IUUC-Tru-118669	Takifugu rubripes	37.73	2.00e-116	414.00
IUUC-Tsy-119373	Tarsius syrichta	36.92	8.00e-77	281.00
IUUC-Tni-120049	Tetraodon nigroviridis	37.87	3.00e-89	321.00
IUUC-Tca-121779	Theobroma cacao	73.74	0.00e+00	2261.00
IUUC-Tre-122195	Trichoderma reesei	39.96	5.00e-107	382.00
IUUC-Tvi-122650	Trichoderma virens	40.07	1.00e-106	380.00
IUUC-Tae-123120	Triticum aestivum	63.85	0.00e+00	1900.00
IUUC-Tur-126295	Triticum urartu	64.60	0.00e+00	1965.00
IUUC-Tme-126964	Tuber melanosporum	40.63	2.00e-106	380.00
IUUC-Tbe-128149	Tupaia belangeri	39.30	3.00e-69	256.00
IUUC-Ttr-128165	Tursiops truncatus	43.23	1.00e-114	407.00
IUUC-Vda-129725	Verticillium dahliae	40.15	1.00e-109	391.00
IUUC-Vpa-130678	Vicugna pacos	43.23	7.00e-115	408.00
IUUC-Vvi-131147	Vitis vinifera	73.03	0.00e+00	2293.00
IUUC-Xtr-132636	Xenopus tropicalis	42.13	1.00e-110	394.00
IUUC-Xma-133458	Xiphophorus maculatus	37.45	9.00e-117	414.00
IUUC-Yli-134481	Yarrowia lipolytica	38.10	4.00e-95	342.00
IUUC-Zma-135782	Zea mays	63.33	0.00e+00	2035.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence