iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000005455.1	ENSONIT00000006857.1	ENSONIP00000006852.1
ENSONIG00000005455.1	ENSONIT00000006858.1	ENSONIP00000006853.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-31	107.0	363	395
UBD/Beta-Prp	6.60e-54	183.5	281	550

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           Htd+v +++f  s+ ++vsGs+Dgt ++W l++
   Q: 363  HTDKVDSIQFchSGERFVSGSRDGTARIWKLHQ 395
           ***********6669***************975 PP

UBD/Beta-Prp

   S: 21   dksllatgsrdgtikvwdvttgkl.....lrslsgheae..........vtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkg 92
           +k++++++++d+t+  w+++  +               +          + + +fsp g +l+tgs+D++i+++ l   +++ ++ l++
   Q: 281  SKRYMLSTGTDATVCFWQWDANNInfsdrP-------HKfterprpgvqTVCSSFSPGGMFLATGSTDDVIRIYYLGsgSPEKISELHE 362
           799******************999545443.......44445555566666778********************665448899****** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqclee.................tlsghdgvvncvvvhpdgnllvsGslDrtvrlW 164
           h+d+v s++f+ sg+++vsGs+d t+r+w+l+++q  +                   +s  +  v++v+++  +n ++++ ++  +++W
   Q: 363  HTDKVDSIQFCHSGERFVSGSRDGTARIWKLHQRQQWRCillnmsatipgvepmseEESYFKPKVTMVAWDRHDNTVITAVNNHLLKVW 451
           ***********************************998899***********988877777889************************* PP
   S: 165  dlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgec......vrtlnghtdnvksvrfspnderlvsgssDg 244
           ++ tg+ll+ l+g h+  v  l+   fd+  + ++s+++dg v +wdl +g+       + + +gh   v + +f+p+++r++++ s+g
   Q: 452  NSYTGQLLHILKG-HEAEVFVLEphpFDP--RIILSAGHDGNVFIWDLLRGTNtqhyfnMIEGQGH-GAVFDCKFTPDGQRFACTDSHG 536
           ************9.*********999999..99****************77763333333333344.667778999************* PP
   S: 245  siriWdlrsgdllk 258
            + i+   s+++  
   Q: 537  HLLIFGFGSSKPYE 550
           **999877777655 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAKNRNISLL ESELYYLISR FLTTGPCRRA AEVLASELEE YQLLPGRLDW LGNEHPRTYE 60
DVVAANRHIA PDHLLQICKQ IGPLLDKEVP SCVPGVHSLL GSGRQSMLRT AKDCDSVRFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTGTTGA GCGAGTGCTC CTCCCCACCC CCTTTTTCCT GTGTTACTCC GCTTTGGCGG 60
AAGTAAGCCG TATCGCTGAG GCCTCATCCT TCCAATGGCG ACTGCAAACA GGCTGAATAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004083	Anas platyrhynchos	57.07	0.00e+00	1595.00
IUUC-Aca-004348	Anolis carolinensis	61.69	0.00e+00	1623.00
IUUC-Ame-010718	Astyanax mexicanus	79.21	0.00e+00	1395.00
IUUC-Cja-019966	Callithrix jacchus	62.37	0.00e+00	1825.00
IUUC-Cpo-021934	Cavia porcellus	63.33	0.00e+00	1828.00
IUUC-Cho-024690	Choloepus hoffmanni	75.07	8.00e-173	602.00
IUUC-Csv-025813	Ciona savignyi	42.17	6.00e-180	624.00
IUUC-Dre-028205	Danio rerio	82.09	0.00e+00	1413.00
IUUC-Dor-030195	Dipodomys ordii	58.75	0.00e+00	875.00
IUUC-Fal-037307	Ficedula albicollis	71.18	0.00e+00	1166.00
IUUC-Gga-040865	Gallus gallus	62.54	0.00e+00	1870.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	58.45	0.00e+00	709.00
IUUC-Lch-049662	Latimeria chalumnae	63.07	0.00e+00	1863.00
IUUC-Lpe-051619	Leersia perrieri	31.88	2.00e-66	249.00
IUUC-Loc-052853	Lepisosteus oculatus	71.73	0.00e+00	2014.00
IUUC-Meu-056739	Macropus eugenii	60.83	0.00e+00	872.00
IUUC-Mga-060165	Meleagris gallopavo	62.82	0.00e+00	1860.00
IUUC-Mmr-061227	Microcebus murinus	63.32	0.00e+00	1830.00
IUUC-Mmu-064075	Mus musculus	63.32	0.00e+00	1831.00
IUUC-Ocu-074456	Oryctolagus cuniculus	62.29	0.00e+00	1818.00
IUUC-Oba-075709	Oryza barthii	30.14	8.00e-61	229.00
IUUC-Obr-076619	Oryza brachyantha	32.13	4.00e-69	257.00
IUUC-Ogl-077493	Oryza glaberrima	26.61	8.00e-30	127.00
IUUC-Opu-083233	Oryza punctata	30.91	2.00e-62	235.00
IUUC-Oru-085195	Oryza rufipogon	30.14	8.00e-61	229.00
IUUC-Psi-093271	Pelodiscus sinensis	61.17	0.00e+00	1652.00
IUUC-Pfo-097318	Poecilia formosa	86.66	0.00e+00	2476.00
IUUC-Pab-097573	Pongo abelii	60.86	0.00e+00	1759.00
IUUC-Rno-105687	Rattus norvegicus	62.86	0.00e+00	1795.00
IUUC-Tgu-116513	Taeniopygia guttata	70.96	0.00e+00	1167.00
IUUC-Tni-120656	Tetraodon nigroviridis	76.36	0.00e+00	2187.00
IUUC-Xtr-132278	Xenopus tropicalis	52.70	0.00e+00	1455.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence