iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020065

Ensembl Protein ID

ENSCAFP00000028581.3

UniProt Accession

E2R7R1; E2R7R1_CANLF

Genbank Protein ID

ENSCAFP00000028581

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03003836

Gene Name

ISG15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000019348.3	ENSCAFT00000030747.3	ENSCAFP00000028581.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	4.70e-26	90.8	89	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekksg 75
           ++ v++ +g++  ++v+ + tVaeLK+++ ++++++++   L+++Gk++ed + L++ygl++ +t+++ ++ +g
   Q: 89   SILVRNNKGRSIAYEVWLTQTVAELKQQVCQQEHVQADLFWLTFEGKPMEDKHQLGEYGLTPQCTVFMNLRLRG 162
           689*****************************************************************999876 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MLEPTAMAGN LTVKMLGGEE FLVPLRDSML ASELKQQIAL KTGVPAFQQR LATHPAGTVL 60
QDGISLIRQG LCPGSTVLLV VKNCNDPLSI LVRNNKGRSI AYEVWLTQTV AELKQQVCQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCATGGTC TGGGCGTTAT TAATATCTTT CTCCAAAATC TGAGTGTTGA CACCTTTCCA 60
GATCCGGGAA GTCATATCTC TCCACCTTGG GAAGCGGTGA AATTTCTCCC AACCCCTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF00240--ubiquitin

SMART

SM00213--UBQ

Gene Ontology

GO:0005576--C:extracellular region
GO:0031386--F:protein tag
GO:0042742--P:defense response to bacterium
GO:0051607--P:defense response to virus
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process
GO:0031397--P:negative regulation of protein ubiquitination
GO:0045071--P:negative regulation of viral genome replication
GO:0030501--P:positive regulation of bone mineralization
GO:0045648--P:positive regulation of erythrocyte differentiation
GO:0032649--P:regulation of interferon-gamma production
GO:0034340--P:response to type I interferon

KEGG

cfa:100855667

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001878	Ailuropoda melanoleuca	85.62	4.00e-75	273.00
IUUC-Aca-004519	Anolis carolinensis	38.46	1.00e-24	105.00
IUUC-Bta-013171	Bos taurus	70.97	5.00e-57	213.00
IUUC-Cja-019835	Callithrix jacchus	70.32	9.00e-59	218.00
IUUC-Cpo-021861	Cavia porcellus	64.90	9.00e-52	195.00
IUUC-Csa-023867	Chlorocebus sabaeus	69.68	4.00e-53	200.00
IUUC-Dno-029882	Dasypus novemcinctus	73.83	5.00e-61	226.00
IUUC-Dor-030951	Dipodomys ordii	72.19	2.00e-55	207.00
IUUC-Eca-034085	Equus caballus	77.92	3.00e-64	236.00
IUUC-Fca-035436	Felis catus	84.52	1.00e-75	275.00
IUUC-Ggo-045637	Gorilla gorilla	70.32	3.00e-57	213.00
IUUC-Hsa-046999	Homo sapiens	70.32	1.00e-52	198.00
IUUC-Itr-048270	Ictidomys tridecemlineatus	69.08	4.00e-56	209.00
IUUC-Laf-053813	Loxodonta africana	68.42	6.00e-56	209.00
IUUC-Mcc-055557	Macaca mulatta	69.68	7.00e-57	212.00
IUUC-Mmr-060685	Microcebus murinus	67.74	7.00e-55	206.00
IUUC-Mdo-062517	Monodelphis domestica	45.03	4.00e-24	103.00
IUUC-Mmu-064385	Mus musculus	65.16	5.00e-47	179.00
IUUC-Mpu-066848	Mustela putorius furo	83.87	3.00e-74	270.00
IUUC-Ocu-074687	Oryctolagus cuniculus	64.47	2.00e-53	201.00
IUUC-Oga-089098	Otolemur garnettii	68.92	2.00e-56	211.00
IUUC-Oar-089908	Ovis aries	72.33	1.00e-62	231.00
IUUC-Ptr-090653	Pan troglodytes	70.32	6.00e-57	213.00
IUUC-Pan-092485	Papio anubis	70.32	2.00e-57	214.00
IUUC-Pab-098308	Pongo abelii	69.03	5.00e-56	209.00
IUUC-Rno-106108	Rattus norvegicus	67.74	3.00e-57	213.00
IUUC-Sha-107193	Sarcophilus harrisii	45.03	2.00e-30	124.00
IUUC-Ssc-115784	Sus scrofa	80.13	2.00e-66	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence