iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034085

Ensembl Protein ID

ENSECAP00000000924.1

UniProt Accession

F7D6U2; F7D6U2_HORSE

Protein Name

Uncharacterized protein

Gene Name

ISG15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000001324.1	ENSECAT00000001183.1	ENSECAP00000000924.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	3.00e-28	97.7	5	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiyk..GkiLeddktLadyglkdgstihllekks 74
           +vk l g    +  ++ s+ V+eLK++i +k+g+pp qqrL     G +L+d ++L + gl +gst++l++++ 
   Q: 5    KVKMLGGEfLVP--LKDSMLVSELKQQIAQKTGVPPFQQRLATHpaGMVLQDRVPLVSQGLGPGSTVVLVVQNC 76
           667777744444..45899***********************8888************************9975 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

GGELKVKMLG GEFLVPLKDS MLVSELKQQI AQKTGVPPFQ QRLATHPAGM VLQDRVPLVS 60
QGLGPGSTVV LVVQNCDTPL SILVRNGKGR SSAYEVRLTQ TVAELKQQVC LRESVQADQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGGGGAGC TGAAGGTGAA GATGCTGGGG GGTGAATTCC TGGTGCCCCT GAAGGACTCC 60
ATGCTGGTGT CGGAGCTGAA GCAGCAGATC GCCCAGAAGA CAGGAGTGCC CCCCTTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF00240--ubiquitin

SMART

SM00213--UBQ

Gene Ontology

GO:0005576--C:extracellular region
GO:0031386--F:protein tag
GO:0042742--P:defense response to bacterium
GO:0051607--P:defense response to virus
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process
GO:0031397--P:negative regulation of protein ubiquitination
GO:0045071--P:negative regulation of viral genome replication
GO:0030501--P:positive regulation of bone mineralization
GO:0045648--P:positive regulation of erythrocyte differentiation
GO:0032649--P:regulation of interferon-gamma production
GO:0034340--P:response to type I interferon

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001878	Ailuropoda melanoleuca	79.74	1.00e-64	238.00
IUUC-Aca-004519	Anolis carolinensis	35.71	2.00e-20	91.70
IUUC-Bta-013171	Bos taurus	72.44	2.00e-56	210.00
IUUC-Cja-019835	Callithrix jacchus	73.72	8.00e-61	225.00
IUUC-Cfa-020065	Canis familiaris	77.92	4.00e-64	236.00
IUUC-Cpo-021861	Cavia porcellus	59.74	3.00e-47	180.00
IUUC-Csa-023867	Chlorocebus sabaeus	72.73	8.00e-54	202.00
IUUC-Dno-029882	Dasypus novemcinctus	75.00	3.00e-63	233.00
IUUC-Dor-030951	Dipodomys ordii	69.13	5.00e-53	199.00
IUUC-Fca-035436	Felis catus	80.13	1.00e-67	248.00
IUUC-Ggo-045637	Gorilla gorilla	71.79	4.00e-57	213.00
IUUC-Hsa-046999	Homo sapiens	73.08	5.00e-54	202.00
IUUC-Itr-048270	Ictidomys tridecemlineatus	67.31	1.00e-53	201.00
IUUC-Laf-053813	Loxodonta africana	67.95	3.00e-53	200.00
IUUC-Mcc-055557	Macaca mulatta	72.73	3.00e-58	216.00
IUUC-Mmr-060685	Microcebus murinus	70.78	5.00e-57	213.00
IUUC-Mdo-062517	Monodelphis domestica	44.44	7.00e-24	102.00
IUUC-Mmu-064385	Mus musculus	65.58	7.00e-44	169.00
IUUC-Mpu-066848	Mustela putorius furo	79.35	4.00e-65	240.00
IUUC-Ocu-074687	Oryctolagus cuniculus	67.31	2.00e-54	204.00
IUUC-Oga-089098	Otolemur garnettii	74.00	5.00e-61	226.00
IUUC-Oar-089908	Ovis aries	73.72	1.00e-60	224.00
IUUC-Ptr-090653	Pan troglodytes	71.79	6.00e-57	213.00
IUUC-Pan-092485	Papio anubis	72.73	4.00e-58	216.00
IUUC-Pab-098308	Pongo abelii	72.44	3.00e-58	216.00
IUUC-Rno-106108	Rattus norvegicus	65.36	1.00e-51	194.00
IUUC-Sha-107193	Sarcophilus harrisii	42.18	4.00e-25	107.00
IUUC-Ssc-115784	Sus scrofa	76.92	2.00e-62	230.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence