iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Smo-109412

Ensembl Protein ID

EFJ14696

UniProt Accession

D8RML3; D8RML3_SELML

Genbank Protein ID

EFJ14696.1; EFJ26358.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

GL377626; GL377584

Gene Name

SINAT5A-1; SINAT5A-2; SELMODRAFT_119614; SELMODRAFT_97849

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_119614	EFJ14696	EFJ14696

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	34.43	5.00e-40	161.00	IUUC-Dme-031755
E3 activity/RING/RING	33.91	1.00e-38	157.00	IUUC-Hsa-046357
E3 activity/RING/RING	34.28	1.00e-38	157.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Selaginella moellendorffii

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAPPNTSYVE VGEAPALLES ETTDVVAEEA GAFVLPPKIP VPAALSSKFG GSPPASVYEL 60
LECPVCTNSM YPPIHQCPNG HTLCSTCKVR VHNRCPTCRY ELGNIRCLAL EKVAESLELP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCTC CAAACACGAG CTATGTCGAA GTGGGAGAGG CGCCGGCGCT GCTGGAGAGC 60
GAGACGACCG ATGTGGTTGC AGAGGAGGCT GGCGCATTCG TCCTGCCGCC AAAGATCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

smo:SELMODRAFT_119614; smo:SELMODRAFT_97849

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	69.23	2.00e-126	444.00
IUUC-Aml-001186	Ailuropoda melanoleuca	34.69	3.00e-39	154.00
IUUC-Atr-003118	Amborella trichopoda	75.56	8.00e-141	491.00
IUUC-Apl-003813	Anas platyrhynchos	34.69	3.00e-39	154.00
IUUC-Aca-005014	Anolis carolinensis	33.68	2.00e-39	155.00
IUUC-Aly-006207	Arabidopsis lyrata	74.68	6.00e-140	489.00
IUUC-Ath-007092	Arabidopsis thaliana	86.77	7.00e-140	489.00
IUUC-Ame-011196	Astyanax mexicanus	35.18	3.00e-39	154.00
IUUC-Bta-012887	Bos taurus	33.56	3.00e-39	154.00
IUUC-Bdi-014729	Brachypodium distachyon	86.54	3.00e-141	493.00
IUUC-Bol-015523	Brassica oleracea	84.09	5.00e-138	482.00
IUUC-Bra-017336	Brassica rapa	85.60	4.00e-137	479.00
IUUC-Cel-018320	Caenorhabditis elegans	30.71	4.00e-35	141.00
IUUC-Cja-019796	Callithrix jacchus	33.91	4.00e-40	157.00
IUUC-Cfa-020642	Canis familiaris	34.69	2.00e-39	155.00
IUUC-Cpo-022348	Cavia porcellus	34.28	5.00e-40	157.00
IUUC-Csa-023974	Chlorocebus sabaeus	33.91	3.00e-40	157.00
IUUC-Cho-024933	Choloepus hoffmanni	33.47	3.00e-35	141.00
IUUC-Cin-025674	Ciona intestinalis	34.15	3.00e-39	154.00
IUUC-Csv-026233	Ciona savignyi	34.55	2.00e-39	154.00
IUUC-Dre-028041	Danio rerio	33.91	5.00e-40	157.00
IUUC-Dno-029764	Dasypus novemcinctus	34.69	3.00e-39	154.00
IUUC-Dor-030489	Dipodomys ordii	30.81	1.00e-18	85.50
IUUC-Dme-031755	Drosophila melanogaster	34.43	3.00e-41	161.00
IUUC-Ete-032423	Echinops telfairi	34.55	1.00e-38	152.00
IUUC-Eca-033536	Equus caballus	34.69	3.00e-39	154.00
IUUC-Eeu-035314	Erinaceus europaeus	34.55	9.00e-39	153.00
IUUC-Fca-035362	Felis catus	34.69	3.00e-39	154.00
IUUC-Fal-037487	Ficedula albicollis	33.91	3.00e-39	154.00
IUUC-Gmo-039091	Gadus morhua	32.85	8.00e-35	139.00
IUUC-Gga-040269	Gallus gallus	34.69	3.00e-39	154.00
IUUC-Gac-042282	Gasterosteus aculeatus	34.28	4.00e-40	157.00
IUUC-Gma-042926	Glycine max	84.44	2.00e-140	490.00
IUUC-Ggo-045444	Gorilla gorilla	33.91	3.00e-40	157.00
IUUC-Hsa-046357	Homo sapiens	33.91	3.00e-40	157.00
IUUC-Hvu-047574	Hordeum vulgare	69.23	1.00e-125	441.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	34.28	5.00e-40	157.00
IUUC-Lch-049504	Latimeria chalumnae	34.69	2.00e-39	154.00
IUUC-Lpe-050879	Leersia perrieri	80.63	4.00e-127	446.00
IUUC-Loc-052191	Lepisosteus oculatus	33.56	3.00e-39	154.00
IUUC-Laf-053668	Loxodonta africana	34.69	3.00e-39	154.00
IUUC-Mcc-054640	Macaca mulatta	33.91	3.00e-40	157.00
IUUC-Meu-055922	Macropus eugenii	33.06	5.00e-34	137.00
IUUC-Mtr-058699	Medicago truncatula	87.69	1.00e-142	498.00
IUUC-Mga-059503	Meleagris gallopavo	33.56	8.00e-40	156.00
IUUC-Mmr-060794	Microcebus murinus	34.28	5.00e-40	157.00
IUUC-Mdo-061971	Monodelphis domestica	33.87	1.00e-35	142.00
IUUC-Mmu-064129	Mus musculus	34.28	3.00e-40	157.00
IUUC-Mac-065670	Musa acuminata	79.33	2.00e-144	504.00
IUUC-Mpu-066331	Mustela putorius furo	35.71	1.00e-39	156.00
IUUC-Mlu-067207	Myotis lucifugus	33.56	2.00e-39	155.00
IUUC-Nle-069706	Nomascus leucogenys	33.91	4.00e-40	157.00
IUUC-Opr-070341	Ochotona princeps	27.11	8.00e-13	66.60
IUUC-Ont-071849	Oreochromis niloticus	34.02	2.00e-40	158.00
IUUC-Oan-073701	Ornithorhynchus anatinus	25.50	1.00e-12	65.90
IUUC-Ocu-074876	Oryctolagus cuniculus	33.91	4.00e-40	157.00
IUUC-Oba-075789	Oryza barthii	80.15	4.00e-134	469.00
IUUC-Obr-076037	Oryza brachyantha	83.27	8.00e-134	469.00
IUUC-Ogl-077148	Oryza glaberrima	80.15	4.00e-134	469.00
IUUC-Ogu-078042	Oryza glumaepatula	80.15	2.00e-134	470.00
IUUC-Oin-079325	Oryza indica	80.15	5.00e-134	469.00
IUUC-Olo-080244	Oryza longistaminata	70.98	1.00e-134	472.00
IUUC-Ome-081318	Oryza meridionalis	81.42	5.00e-127	446.00
IUUC-Oni-082163	Oryza nivara	80.15	4.00e-134	469.00
IUUC-Opu-084065	Oryza punctata	81.03	1.00e-126	444.00
IUUC-Oru-084833	Oryza rufipogon	80.15	5.00e-134	469.00
IUUC-Osa-085316	Oryza sativa	80.15	5.00e-134	469.00
IUUC-Ola-086814	Oryzias latipes	34.28	4.00e-40	157.00
IUUC-Olu-087748	Ostreococcus lucimarinus	36.36	1.20e-02	33.10
IUUC-Oga-088114	Otolemur garnettii	36.03	5.00e-40	157.00
IUUC-Oar-089323	Ovis aries	32.64	3.00e-39	154.00
IUUC-Ptr-090692	Pan troglodytes	33.91	5.00e-40	157.00
IUUC-Pan-092012	Papio anubis	33.91	3.00e-40	157.00
IUUC-Psi-093687	Pelodiscus sinensis	34.69	3.00e-39	154.00
IUUC-Pma-094387	Petromyzon marinus	33.45	1.00e-39	155.00
IUUC-Ppa-095212	Physcomitrella patens	81.35	3.00e-150	523.00
IUUC-Pfo-097134	Poecilia formosa	34.28	4.00e-40	157.00
IUUC-Pab-097555	Pongo abelii	33.91	3.00e-40	157.00
IUUC-Pop-100033	Populus trichocarpa	86.54	9.00e-140	488.00
IUUC-Pca-100328	Procavia capensis	32.67	5.00e-33	134.00
IUUC-Ppe-101960	Prunus persica	85.71	1.00e-143	501.00
IUUC-Pva-103132	Pteropus vampyrus	25.79	3.00e-11	61.20
IUUC-Rno-104866	Rattus norvegicus	34.28	3.00e-40	157.00
IUUC-Sha-106547	Sarcophilus harrisii	33.56	3.00e-39	154.00
IUUC-Sit-110245	Setaria italica	83.66	2.00e-133	468.00
IUUC-Sly-111259	Solanum lycopersicum	86.77	2.00e-138	484.00
IUUC-Stu-112571	Solanum tuberosum	86.77	2.00e-138	484.00
IUUC-Sbi-114035	Sorghum bicolor	84.05	1.00e-134	471.00
IUUC-Ssc-116441	Sus scrofa	33.07	2.00e-35	141.00
IUUC-Tgu-116579	Taeniopygia guttata	34.69	3.00e-39	154.00
IUUC-Tru-118250	Takifugu rubripes	33.94	7.00e-38	149.00
IUUC-Tsy-119548	Tarsius syrichta	29.63	3.00e-07	47.80
IUUC-Tni-120488	Tetraodon nigroviridis	34.67	9.00e-38	149.00
IUUC-Tca-121517	Theobroma cacao	86.92	9.00e-141	491.00
IUUC-Tae-123647	Triticum aestivum	69.23	2.00e-126	444.00
IUUC-Tur-126259	Triticum urartu	79.40	1.00e-131	461.00
IUUC-Ttr-129166	Tursiops truncatus	36.32	8.00e-37	146.00
IUUC-Vpa-130799	Vicugna pacos	30.41	1.00e-16	78.20
IUUC-Vvi-131233	Vitis vinifera	76.45	3.00e-142	496.00
IUUC-Xtr-132553	Xenopus tropicalis	34.53	4.00e-40	157.00
IUUC-Xma-133670	Xiphophorus maculatus	34.28	4.00e-40	157.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence