iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-131993

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01002118

Gene Name

cdc20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000025623.2	ENSXETT00000008405.3	ENSXETP00000008405.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	3.80e-140	466.6	180	491
E3 adaptor/Cullin RING/DCX/DWD	4.30e-26	90.1	319	353

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p++vldap++r+d+ylnL+dWss+n lavaL+ svylw+ +tgd++ l ++ + +++++svswi+eg++lavGt+++ev+++Dv+++k+
   Q: 180  PDRVLDAPDIRNDYYLNLIDWSSQNFLAVALNDSVYLWNYATGDIILLLQMeHSEEYISSVSWIKEGNYLAVGTSNSEVQLWDVQQQKR 268
           689************************************************77899********************************* PP
   S: 89   vrtltghsarvgaLsWnaevls....sGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse... 170
           +r++t+hs+rvgaLsWn+++ls    sGsr g+i+h+dvrv+++++stl++h+qevCGlkw+ d+++LasG nDn v+vw   + +   
   Q: 269  LRNMTSHSSRVGALSWNNHILSspalSGSRTGHIHHHDVRVAQHHVSTLTGHTQEVCGLKWSPDGRYLASGANDNLVNVWPCVQGDsge 357
           *********************844446*****************************************************998887788 PP
   S: 171  ..PlkkfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypsl 257
             P+++f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++g++l+++dt+sqvcs+lws ++kel+s+hGfa+n+++lwkyp++
   Q: 358  fsPVQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGTCLNSVDTHSQVCSILWSTNYKELISGHGFAQNQLVLWKYPTM 446
           99*************************************************************************************** PP
   S: 258  skvaelkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           ++v+elkgh+aRvl+la+spdg ++++aa+Detlr+wk+f+ +++
   Q: 447  TRVTELKGHTARVLNLAISPDGCTVASAAADETLRLWKCFEVDPV 491
           ****************************************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gHt +v++l++ +d ++l+sG++D+ + vW   +g
   Q: 319  GHTQEVCGLKWsPDgRYLASGANDNLVNVWPCVQG 353
           8***********999***************87776 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MAQFAFETDI NSILKLDTPI TNAPLARWQR KAKEGNCSSL NTSANTSTMS PMKTSNRSHS 60
SSKTPSKTPG KSGPKMQGTP SRAGGDRFIP NRSAMQMDVA SFLLCKENEP ADTSPTKKEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAACTGGTAA GCTATTCTTT AGCTGGCTAA GGGTTACAGA AGCATACAGA CGCCGGGCTT 60
TGCGGTGAGT GTAGTTTAAT ACAACAGAGC AGCGGGATTG ACGTCTTTTG TGGGGGGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	48.24	1.00e-111	396.00
IUUC-Aml-001545	Ailuropoda melanoleuca	71.93	0.00e+00	757.00
IUUC-Atr-003103	Amborella trichopoda	46.01	1.00e-107	383.00
IUUC-Apl-003255	Anas platyrhynchos	82.62	0.00e+00	778.00
IUUC-Aca-004920	Anolis carolinensis	75.54	0.00e+00	778.00
IUUC-Aly-006253	Arabidopsis lyrata	48.83	3.00e-112	398.00
IUUC-Ath-006795	Arabidopsis thaliana	49.18	2.00e-113	402.00
IUUC-Ate-010479	Aspergillus terreus	40.93	4.00e-91	328.00
IUUC-Ame-010850	Astyanax mexicanus	64.95	2.00e-97	348.00
IUUC-Bgr-012059	Blumeria graminis	49.22	3.00e-94	338.00
IUUC-Bta-012625	Bos taurus	72.71	0.00e+00	764.00
IUUC-Bci-013607	Botrytis cinerea	47.67	4.00e-95	342.00
IUUC-Bdi-014344	Brachypodium distachyon	48.93	3.00e-111	395.00
IUUC-Bol-015368	Brassica oleracea	49.18	3.00e-112	399.00
IUUC-Bra-016738	Brassica rapa	48.09	9.00e-110	390.00
IUUC-Cja-019132	Callithrix jacchus	72.51	0.00e+00	767.00
IUUC-Cfa-020780	Canis familiaris	71.54	0.00e+00	753.00
IUUC-Cpo-022223	Cavia porcellus	72.32	0.00e+00	721.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	47.98	5.00e-113	400.00
IUUC-Csa-023666	Chlorocebus sabaeus	72.51	0.00e+00	765.00
IUUC-Cho-024920	Choloepus hoffmanni	71.13	6.00e-123	434.00
IUUC-Cin-025675	Ciona intestinalis	50.89	1.00e-135	476.00
IUUC-Csv-026019	Ciona savignyi	52.59	6.00e-132	464.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	41.28	2.00e-95	342.00
IUUC-Cne-026872	Cryptococcus neoformans	45.82	7.00e-87	314.00
IUUC-Cme-027234	Cyanidioschyzon merolae	50.86	5.00e-101	361.00
IUUC-Dre-028026	Danio rerio	63.09	0.00e+00	658.00
IUUC-Dno-028865	Dasypus novemcinctus	71.54	0.00e+00	758.00
IUUC-Dor-030958	Dipodomys ordii	73.24	0.00e+00	767.00
IUUC-Dse-031391	Dothistroma septosporum	47.98	6.00e-97	348.00
IUUC-Dme-031905	Drosophila melanogaster	49.16	1.00e-140	492.00
IUUC-Ete-032387	Echinops telfairi	69.20	0.00e+00	726.00
IUUC-Eca-033522	Equus caballus	66.15	0.00e+00	678.00
IUUC-Eeu-035059	Erinaceus europaeus	66.93	0.00e+00	662.00
IUUC-Fca-036346	Felis catus	73.85	0.00e+00	692.00
IUUC-Fal-037558	Ficedula albicollis	78.52	0.00e+00	799.00
IUUC-Fox-037850	Fusarium oxysporum	47.09	6.00e-93	334.00
IUUC-Fso-038375	Fusarium solani	40.52	2.00e-94	339.00
IUUC-Gmo-039284	Gadus morhua	64.13	0.00e+00	662.00
IUUC-Ggr-039864	Gaeumannomyces graminis	49.06	2.00e-93	336.00
IUUC-Gga-040790	Gallus gallus	80.61	0.00e+00	832.00
IUUC-Gac-041431	Gasterosteus aculeatus	62.57	0.00e+00	647.00
IUUC-Gma-043489	Glycine max	47.91	1.00e-110	392.00
IUUC-Ggo-045052	Gorilla gorilla	72.71	0.00e+00	764.00
IUUC-Hsa-046305	Homo sapiens	72.71	0.00e+00	764.00
IUUC-Hvu-047476	Hordeum vulgare	46.80	6.00e-111	394.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	72.71	0.00e+00	727.00
IUUC-Lch-050174	Latimeria chalumnae	65.50	0.00e+00	630.00
IUUC-Lpe-050954	Leersia perrieri	49.02	6.00e-103	367.00
IUUC-Loc-052638	Lepisosteus oculatus	64.13	0.00e+00	640.00
IUUC-Lma-052998	Leptosphaeria maculans	42.16	2.00e-99	356.00
IUUC-Laf-053742	Loxodonta africana	72.32	0.00e+00	760.00
IUUC-Mcc-054948	Macaca mulatta	72.51	0.00e+00	765.00
IUUC-Meu-056013	Macropus eugenii	70.10	5.00e-120	424.00
IUUC-Mor-057277	Magnaporthe oryzae	41.87	4.00e-92	332.00
IUUC-Mpo-057624	Magnaporthe poae	48.88	6.00e-92	331.00
IUUC-Mtr-057725	Medicago truncatula	47.71	1.00e-106	379.00
IUUC-Mga-060102	Meleagris gallopavo	80.00	0.00e+00	827.00
IUUC-Mmr-061615	Microcebus murinus	73.79	0.00e+00	763.00
IUUC-Mdo-061982	Monodelphis domestica	72.69	0.00e+00	665.00
IUUC-Mmu-063864	Mus musculus	73.88	0.00e+00	766.00
IUUC-Mac-064861	Musa acuminata	47.07	1.00e-111	396.00
IUUC-Mpu-066502	Mustela putorius furo	72.71	0.00e+00	753.00
IUUC-Mlu-067277	Myotis lucifugus	69.84	0.00e+00	731.00
IUUC-Nle-070149	Nomascus leucogenys	72.32	0.00e+00	758.00
IUUC-Opr-070778	Ochotona princeps	70.51	2.00e-153	535.00
IUUC-Ont-071660	Oreochromis niloticus	64.66	0.00e+00	635.00
IUUC-Oan-073677	Ornithorhynchus anatinus	64.53	0.00e+00	633.00
IUUC-Ocu-073797	Oryctolagus cuniculus	72.21	0.00e+00	756.00
IUUC-Oba-075514	Oryza barthii	46.88	7.00e-104	370.00
IUUC-Obr-076018	Oryza brachyantha	44.56	2.00e-108	385.00
IUUC-Ogl-077254	Oryza glaberrima	46.88	7.00e-104	370.00
IUUC-Ogu-078562	Oryza glumaepatula	46.65	2.00e-103	369.00
IUUC-Oin-080094	Oryza indica	46.88	7.00e-104	370.00
IUUC-Olo-080449	Oryza longistaminata	46.64	1.00e-104	372.00
IUUC-Ome-081186	Oryza meridionalis	48.29	2.00e-107	384.00
IUUC-Oni-082243	Oryza nivara	46.88	7.00e-104	370.00
IUUC-Opu-084007	Oryza punctata	46.43	3.00e-103	368.00
IUUC-Oru-084357	Oryza rufipogon	46.65	3.00e-103	368.00
IUUC-Osa-086094	Oryza sativa	46.88	9.00e-104	370.00
IUUC-Ola-086907	Oryzias latipes	63.90	2.00e-170	592.00
IUUC-Olu-087647	Ostreococcus lucimarinus	50.23	2.00e-119	422.00
IUUC-Oga-088184	Otolemur garnettii	71.79	0.00e+00	751.00
IUUC-Oar-090023	Ovis aries	70.62	0.00e+00	696.00
IUUC-Ptr-090935	Pan troglodytes	72.07	0.00e+00	715.00
IUUC-Pan-091845	Papio anubis	72.51	0.00e+00	765.00
IUUC-Psi-093188	Pelodiscus sinensis	81.20	0.00e+00	875.00
IUUC-Pma-094187	Petromyzon marinus	52.27	2.00e-144	505.00
IUUC-Pno-094809	Phaeosphaeria nodorum	41.59	3.00e-99	355.00
IUUC-Ppa-095687	Physcomitrella patens	49.04	2.00e-120	425.00
IUUC-Pfo-097429	Poecilia formosa	59.45	4.00e-162	564.00
IUUC-Pab-098603	Pongo abelii	72.51	0.00e+00	764.00
IUUC-Pop-098890	Populus trichocarpa	46.80	6.00e-106	377.00
IUUC-Pca-101062	Procavia capensis	71.54	0.00e+00	746.00
IUUC-Ppe-101865	Prunus persica	49.18	2.00e-101	362.00
IUUC-Pva-102925	Pteropus vampyrus	72.71	0.00e+00	776.00
IUUC-Pte-104142	Pyrenophora teres	41.85	8.00e-99	354.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	41.63	3.00e-98	352.00
IUUC-Rno-106005	Rattus norvegicus	73.88	0.00e+00	763.00
IUUC-Sha-107472	Sarcophilus harrisii	72.32	0.00e+00	759.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.08	7.00e-94	337.00
IUUC-Spo-108075	Schizosaccharomyces pombe	42.55	3.00e-93	335.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	47.09	8.00e-94	337.00
IUUC-Smo-108922	Selaginella moellendorffii	48.28	1.00e-119	422.00
IUUC-Sit-110732	Setaria italica	48.78	2.00e-108	385.00
IUUC-Sly-111202	Solanum lycopersicum	48.19	3.00e-112	398.00
IUUC-Stu-112024	Solanum tuberosum	46.25	3.00e-112	398.00
IUUC-Sar-113092	Sorex araneus	69.98	0.00e+00	699.00
IUUC-Sbi-114207	Sorghum bicolor	47.29	2.00e-110	392.00
IUUC-Ssc-115710	Sus scrofa	72.32	0.00e+00	761.00
IUUC-Tgu-117100	Taeniopygia guttata	78.52	0.00e+00	804.00
IUUC-Tru-118184	Takifugu rubripes	57.48	8.00e-140	489.00
IUUC-Tsy-118892	Tarsius syrichta	72.16	2.00e-125	441.00
IUUC-Tni-120474	Tetraodon nigroviridis	61.55	4.00e-170	590.00
IUUC-Tca-120949	Theobroma cacao	48.71	9.00e-111	393.00
IUUC-Tre-122211	Trichoderma reesei	39.87	3.00e-93	335.00
IUUC-Tvi-122531	Trichoderma virens	39.78	3.00e-93	335.00
IUUC-Tae-122784	Triticum aestivum	45.77	9.00e-112	396.00
IUUC-Tur-126193	Triticum urartu	46.80	1.00e-111	396.00
IUUC-Tme-126905	Tuber melanosporum	48.70	1.00e-94	340.00
IUUC-Tbe-127384	Tupaia belangeri	79.80	1.00e-148	519.00
IUUC-Ttr-128511	Tursiops truncatus	71.93	0.00e+00	753.00
IUUC-Vda-129993	Verticillium dahliae	40.47	2.00e-95	343.00
IUUC-Vvi-131245	Vitis vinifera	48.86	1.00e-99	356.00
IUUC-Xma-133332	Xiphophorus maculatus	63.69	4.00e-180	624.00
IUUC-Yli-134501	Yarrowia lipolytica	50.00	3.00e-100	358.00
IUUC-Zma-135456	Zea mays	45.84	1.00e-107	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence