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Tag Content
UUCD2 ID IUUC-Aml-001400
UUCD1 version UUC-AiM-01077
Ensembl Protein ID ENSAMEP00000003144.1
UniProt Accession G1L8C8; G1L8C8_AILME
Genbank Protein ID ENSAMEP00000003144
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01131088
Gene Name USP37
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000002927.1 ENSAMET00000003274.1 ENSAMEP00000003144.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.40e-86 290.8 343 952
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +G++NlgNtCYmN++LQ+L+++++++++ll+   + ++++  k p ++l++ +++l+ +    +s++k+   +++++a++++ae+fsgy
   Q: 343  QGFSNLGNTCYMNAILQSLFSLQSFANDLLK---QGIPWK--KIPLNALIRRFAHLLVKKDicNSETKKDLLKKVKNAISATAERFSGY 426
           69*****************************...*****9..679999999999999776567************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +q+Da+Efl+++ldql+e+++k  nk++++e    ++++sd+   + ++ +++++ ++++++++++i+c++c+++  ++e+f+dls+++
   Q: 427  MQNDAHEFLSQCLDQLKEDMEK-LNKTWKTEPVPGEENSSDI---SATRVYTCPVITNLEFEVQHSIICKACGEIIPKREQFNDLSIDL 511
           ********************55.8888888888887777777...7999**************************************** PP
   S: 177  pgkeetkke.slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           p++++  ++ s+qd+L+ f+++eele    y+cekc +k+ a  ++k+++lP++LilhLkR+sf+ + + ++ki ++v +p+ L+ls++
   Q: 512  PRRKKPLPPrSIQDSLDLFFRAEELE----YSCEKCGGKC-ALVRHKFNRLPRILILHLKRYSFNVTLSLNNKIGQQVIIPRYLTLSSH 595
           *999886545***************9....*********9.89999******************************************* PP
   S: 265  cts...................................................................................... 267
           ct+                                                                                      
   Q: 596  CTEntkppftlgwsahmaisrplkasqmvnscitspstpsknftfksksslalcldsdsedelkrsvalsqrlcemsgceqqqedlekd 684
           ***9*******************999999999999999999999999999999999999999999999999999999999999888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 685  skscriepdkselensgfdgmseeellaavlemskressptlshedddkptsspdtgfaeddiqempenqepvetekpktvtepdsasf 773
           88888888888888888888888888888888888888888888877777777777777777777777777777776666666666666 PP
   S: 268  ...............peekqke................................................................... 274
                          p     e                                                                   
   Q: 774  teitkdcdenkenktP-----Egsqgevdwlqqydmerereeqelqqalaqslqeqeaweqkedddlkratelslqefnnsfldslgsd 857
           6666666655555550.....05555555555555555555666666666666666777777777777777777888888888888888 PP
   S: 275  ..............................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaY 331
                                         +++Y+Li+vv+H G ++ssGHY+++v++ k++ W++++D +V++++e++v++++++++Y
   Q: 858  edsgnedvldmeyteaeaeelkrnaetgnlPHSYRLISVVSHIGsTSSSGHYISDVYDIKKQaWFTYNDLEVSKIQEASVQSDRDRSGY 946
           888888888888888888889999999999****************************99999************************** PP
   S: 332  vlfYkr 337
           ++fY++
   Q: 947  IFFYMH 952
           ****98 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MSPLKIHGPI RIRSMQTGIT KWKEGSFEIV EKENKVSLVV HYNTGGIPRI FQLSHNIKNV 60
VLRPSGAKQS RLMLTLQDNS FLSIDKVPSK DAEEMRLFLD AVHQNRLHAA MKPSQGSGSF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001400|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCTCCTC TGAAGATACA CGGTCCTATC AGAATTCGAA GTATGCAGAC TGGAATTACA 60
AAATGGAAAG AAGGGTCCTT TGAAATTGTG GAAAAAGAGA ATAAAGTCAG CCTAGTAGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001400|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0006275--P:regulation of DNA replication
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-004033 Anas platyrhynchos 77.60 0.00e+00 1442.00
IUUC-Aca-005370 Anolis carolinensis 70.48 0.00e+00 1336.00
IUUC-Ame-011884 Astyanax mexicanus 57.74 0.00e+00 989.00
IUUC-Bta-012725 Bos taurus 95.92 0.00e+00 1731.00
IUUC-Cja-019939 Callithrix jacchus 95.32 0.00e+00 1682.00
IUUC-Cfa-020835 Canis familiaris 98.98 0.00e+00 1858.00
IUUC-Cpo-022067 Cavia porcellus 94.00 0.00e+00 1570.00
IUUC-Cre-022867 Chlamydomonas reinhardtii 29.22 5.00e-24 106.00
IUUC-Csa-023085 Chlorocebus sabaeus 95.62 0.00e+00 1754.00
IUUC-Cho-024390 Choloepus hoffmanni 87.99 2.00e-167 582.00
IUUC-Cin-025496 Ciona intestinalis 37.65 1.00e-43 171.00
IUUC-Csv-025812 Ciona savignyi 36.61 8.00e-42 165.00
IUUC-Dre-028255 Danio rerio 57.59 0.00e+00 945.00
IUUC-Dno-028986 Dasypus novemcinctus 95.32 0.00e+00 1720.00
IUUC-Dor-031062 Dipodomys ordii 79.51 0.00e+00 874.00
IUUC-Ete-032359 Echinops telfairi 83.40 0.00e+00 821.00
IUUC-Eca-033964 Equus caballus 95.92 0.00e+00 1759.00
IUUC-Eeu-034492 Erinaceus europaeus 86.75 0.00e+00 838.00
IUUC-Fca-036359 Felis catus 97.35 0.00e+00 1784.00
IUUC-Fal-037640 Ficedula albicollis 77.58 0.00e+00 1412.00
IUUC-Gmo-039600 Gadus morhua 54.25 0.00e+00 927.00
IUUC-Gga-040126 Gallus gallus 76.87 0.00e+00 1377.00
IUUC-Gac-041557 Gasterosteus aculeatus 53.90 0.00e+00 910.00
IUUC-Ggo-045571 Gorilla gorilla 90.22 0.00e+00 1516.00
IUUC-Hsa-046043 Homo sapiens 94.60 0.00e+00 1707.00
IUUC-Itr-048207 Ictidomys tridecemlineatus 93.98 0.00e+00 1704.00
IUUC-Lch-050357 Latimeria chalumnae 64.81 0.00e+00 1040.00
IUUC-Loc-052849 Lepisosteus oculatus 61.03 0.00e+00 999.00
IUUC-Laf-054570 Loxodonta africana 94.50 0.00e+00 1686.00
IUUC-Mcc-054989 Macaca mulatta 95.30 0.00e+00 1617.00
IUUC-Meu-056273 Macropus eugenii 79.48 7.00e-98 352.00
IUUC-Mga-059814 Meleagris gallopavo 75.58 0.00e+00 1377.00
IUUC-Mmr-061726 Microcebus murinus 94.50 0.00e+00 1734.00
IUUC-Mdo-062974 Monodelphis domestica 85.14 0.00e+00 1573.00
IUUC-Mmu-064069 Mus musculus 90.20 0.00e+00 1620.00
IUUC-Mpu-066008 Mustela putorius furo 98.78 0.00e+00 1782.00
IUUC-Nle-069259 Nomascus leucogenys 95.62 0.00e+00 1710.00
IUUC-Opr-070882 Ochotona princeps 96.73 2.00e-117 416.00
IUUC-Ont-072441 Oreochromis niloticus 54.90 0.00e+00 924.00
IUUC-Oan-073151 Ornithorhynchus anatinus 76.98 1.00e-120 425.00
IUUC-Ocu-074879 Oryctolagus cuniculus 93.78 0.00e+00 1700.00
IUUC-Ola-087007 Oryzias latipes 53.39 0.00e+00 886.00
IUUC-Oga-088385 Otolemur garnettii 93.41 0.00e+00 1719.00
IUUC-Oar-090305 Ovis aries 95.92 0.00e+00 1760.00
IUUC-Ptr-091299 Pan troglodytes 95.31 0.00e+00 1712.00
IUUC-Pan-091996 Papio anubis 95.49 0.00e+00 1706.00
IUUC-Psi-093176 Pelodiscus sinensis 78.33 0.00e+00 1447.00
IUUC-Pma-094331 Petromyzon marinus 48.42 0.00e+00 752.00
IUUC-Ppa-095732 Physcomitrella patens 30.25 3.00e-24 106.00
IUUC-Pfo-096503 Poecilia formosa 56.19 0.00e+00 928.00
IUUC-Pab-098543 Pongo abelii 93.66 0.00e+00 909.00
IUUC-Pca-101099 Procavia capensis 88.17 0.00e+00 1309.00
IUUC-Pva-103163 Pteropus vampyrus 90.01 0.00e+00 1637.00
IUUC-Rno-105766 Rattus norvegicus 91.33 0.00e+00 1637.00
IUUC-Sha-106610 Sarcophilus harrisii 81.79 0.00e+00 1479.00
IUUC-Sar-113256 Sorex araneus 91.38 5.00e-113 402.00
IUUC-Ssc-116353 Sus scrofa 95.73 0.00e+00 1709.00
IUUC-Tgu-116971 Taeniopygia guttata 77.07 0.00e+00 1384.00
IUUC-Tru-117932 Takifugu rubripes 44.41 0.00e+00 639.00
IUUC-Tsy-119185 Tarsius syrichta 90.34 0.00e+00 1132.00
IUUC-Tni-119842 Tetraodon nigroviridis 59.81 2.00e-110 392.00
IUUC-Tbe-127281 Tupaia belangeri 84.19 0.00e+00 659.00
IUUC-Ttr-128177 Tursiops truncatus 96.68 0.00e+00 1364.00
IUUC-Vpa-130031 Vicugna pacos 96.23 0.00e+00 1794.00
IUUC-Xtr-132949 Xenopus tropicalis 65.49 0.00e+00 1164.00
Created Date 25-Jun-2017

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