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Tag Content
UUCD2 ID IUUC-Dre-028255
UUCD1 version UUC-DaR-01472
Ensembl Protein ID ENSDARP00000108006.1
UniProt Accession H9KUW6; H9KUW6_DANRE
Genbank Protein ID ENSDARP00000108006
Protein Name Ubiquitin carboxyl-terminal hydrolase 37
Genbank Nucleotide ID CT583711
Gene Name usp37
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000040990.7 ENSDART00000082300.5 ENSDARP00000076736.4
ENSDARG00000040990.7 ENSDART00000130720.2 ENSDARP00000108006.1
ENSDARG00000040990.7 ENSDART00000129632.2 ENSDARP00000110966.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.40e-82 277.3 322 911
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +G++NlgNtCYmN++LQ+L+++p++ ++ll+   + ++++    p ++ll+ +++l+++      + k+   r++++a++++ae+fsgy
   Q: 322  QGFSNLGNTCYMNAILQSLFSLPSFSNDLLK---QGIPWK--RVPINALLRRFAHLLAKKDisPPEVKKDLLRRVKNAISSTAERFSGY 405
           69*****************************...*****9..5688999999999998886667788899999**************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           +q+Da+Efl+++ldql+e+++k  nk++++e ++ ++ +s     e ++ + ++++++ +++++++++i+c++c++v  ++e+f+dls+
   Q: 406  MQNDAHEFLSQCLDQLKEDVEK-INKSWKNEPSAWDEPQSTRlaDEVDTSRIYTCPVTVNMEFEVQHTITCKSCGEVVLKREQFNDLSI 493
           ********************76.5555555554443333333335567788899*********************************** PP
   S: 175  pvpgkeetkke.slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           ++p++++t +  s+qd+L+ f++ ee+e    y+cekc +k  a+ ++k+++lP+vLilhLkR+s++ + + ++k+ ++v +p+ L+l 
   Q: 494  DLPRRRKTLPMrSIQDSLDLFFRMEEIE----YSCEKCSGKA-ATVSHKFSRLPRVLILHLKRYSYNTQLSLNSKLGQQVLIPKYLTLL 577
           ***998876544***************9....*******999.9********************************************* PP
   S: 263  pfcts.................................................................................... 267
           ++ct+                                                                                    
   Q: 578  SHCTDatrsplslgwsaqnalsrtlkisqsvnsstlrrasqrpessgsvlcdsdsdeelvrkvarkhhpdddradephhqhhphaaveq 666
           *****999999999999999999999999999999999999999999999999999888888888888888888888888888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 667  sefngindeemlaavlemsrhdtslcagpdeepssspdtgfgdadahdltqhlelldaekqptdalesldltmdenkenqtpdglqgel 755
           88888888888888888888888888888887777777777777777777777777777777777777777776666666666666666 PP
   S: 268  ............peekqke...................................................................... 274
                       +     e                                                                      
   Q: 756  dwvqqysleqerE-----Eqelqqalaqslqeqearemredddlkratelslqefnnslpellcsdedsgnedgldmeyseaeaeelkk 839
           6666655555550.....05555566666666666666677777777777777777777777777777777788888888888888888 PP
   S: 275  .......kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
                  +++++Li+vv+H G s+ssGHY+++v++ k++ Wl+++D  V+ ++e++v++++++++Y++fY++
   Q: 840  naetgelPNSFRLISVVSHIGsSSSSGHYISDVYDMKKQsWLTYNDLDVSRTQESTVQRDRDRSGYIFFYMH 911
           8999999****************************88888******************************98 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MAAAVPRLTS GGAVRIRIRC GELGTTKWRE GVIEIQERDN KINLLVKFNS GGAPRVFQLS 60
HNVKSVSWFQ THGPNRMTLT LKDSCIVMMD KLNMLVAKKM KEYLETVKLG KPAVFKTNQG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028255|DUB,USP|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CACATCATCT CACCTCCCAT TTCCGCTCTA AATTTTCACA TTCCCGCCAT CATCGGAAGC 60
TCGTGGGACT CGAGCGCAGA ATCTCCATCA TCACAGCCGG CAAAACTCAC CCGCAAACAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028255|DUB,USP|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001400 Ailuropoda melanoleuca 57.19 0.00e+00 951.00
IUUC-Apl-004033 Anas platyrhynchos 57.29 0.00e+00 964.00
IUUC-Aca-005370 Anolis carolinensis 56.28 0.00e+00 933.00
IUUC-Ame-011884 Astyanax mexicanus 79.47 0.00e+00 1433.00
IUUC-Bta-012725 Bos taurus 57.06 0.00e+00 937.00
IUUC-Cja-019939 Callithrix jacchus 56.63 0.00e+00 932.00
IUUC-Cfa-020835 Canis familiaris 57.55 0.00e+00 963.00
IUUC-Cpo-022067 Cavia porcellus 55.61 0.00e+00 847.00
IUUC-Cre-022867 Chlamydomonas reinhardtii 32.00 6.00e-29 122.00
IUUC-Csa-023085 Chlorocebus sabaeus 57.06 0.00e+00 952.00
IUUC-Cho-024390 Choloepus hoffmanni 42.17 2.00e-64 241.00
IUUC-Cin-025496 Ciona intestinalis 34.37 5.00e-48 186.00
IUUC-Csv-025812 Ciona savignyi 36.29 2.00e-41 164.00
IUUC-Dno-028986 Dasypus novemcinctus 56.82 0.00e+00 940.00
IUUC-Dor-031062 Dipodomys ordii 45.09 1.00e-130 460.00
IUUC-Ete-032359 Echinops telfairi 59.69 6.00e-124 439.00
IUUC-Eca-033964 Equus caballus 57.16 0.00e+00 954.00
IUUC-Eeu-034492 Erinaceus europaeus 54.87 1.00e-127 451.00
IUUC-Fca-036359 Felis catus 56.59 0.00e+00 954.00
IUUC-Fal-037640 Ficedula albicollis 57.10 0.00e+00 934.00
IUUC-Gmo-039600 Gadus morhua 70.49 0.00e+00 1211.00
IUUC-Gga-040126 Gallus gallus 56.57 0.00e+00 917.00
IUUC-Gac-041557 Gasterosteus aculeatus 69.57 0.00e+00 1210.00
IUUC-Ggo-045571 Gorilla gorilla 53.85 0.00e+00 824.00
IUUC-Hsa-046043 Homo sapiens 56.75 0.00e+00 946.00
IUUC-Itr-048207 Ictidomys tridecemlineatus 56.41 0.00e+00 933.00
IUUC-Lch-050357 Latimeria chalumnae 54.85 9.00e-174 604.00
IUUC-Loc-052849 Lepisosteus oculatus 69.78 0.00e+00 1188.00
IUUC-Laf-054570 Loxodonta africana 55.72 0.00e+00 932.00
IUUC-Mcc-054989 Macaca mulatta 55.83 0.00e+00 864.00
IUUC-Meu-056273 Macropus eugenii 38.37 3.00e-85 310.00
IUUC-Mga-059814 Meleagris gallopavo 55.25 0.00e+00 901.00
IUUC-Mmr-061726 Microcebus murinus 56.79 0.00e+00 948.00
IUUC-Mdo-062974 Monodelphis domestica 56.81 0.00e+00 967.00
IUUC-Mmu-064069 Mus musculus 56.18 0.00e+00 916.00
IUUC-Mpu-066008 Mustela putorius furo 57.45 0.00e+00 952.00
IUUC-Mlu-068224 Myotis lucifugus 33.62 2.00e-103 370.00
IUUC-Nle-069259 Nomascus leucogenys 56.44 0.00e+00 941.00
IUUC-Opr-070882 Ochotona princeps 74.89 2.00e-92 334.00
IUUC-Ont-072441 Oreochromis niloticus 70.91 0.00e+00 1236.00
IUUC-Oan-073151 Ornithorhynchus anatinus 61.87 2.00e-95 342.00
IUUC-Ocu-074879 Oryctolagus cuniculus 56.33 0.00e+00 931.00
IUUC-Ola-087007 Oryzias latipes 67.19 0.00e+00 1098.00
IUUC-Oga-088385 Otolemur garnettii 56.15 0.00e+00 947.00
IUUC-Oar-090305 Ovis aries 56.85 0.00e+00 950.00
IUUC-Ptr-091299 Pan troglodytes 56.76 0.00e+00 945.00
IUUC-Pan-091996 Papio anubis 57.56 0.00e+00 932.00
IUUC-Psi-093176 Pelodiscus sinensis 56.78 0.00e+00 947.00
IUUC-Pma-094331 Petromyzon marinus 45.52 0.00e+00 662.00
IUUC-Ppa-095685 Physcomitrella patens 29.88 6.00e-24 106.00
IUUC-Pfo-096503 Poecilia formosa 70.72 0.00e+00 1183.00
IUUC-Pab-098543 Pongo abelii 60.14 6.00e-154 538.00
IUUC-Pca-101099 Procavia capensis 55.94 0.00e+00 751.00
IUUC-Pva-103163 Pteropus vampyrus 55.68 0.00e+00 652.00
IUUC-Rno-105766 Rattus norvegicus 56.17 0.00e+00 912.00
IUUC-Sha-106610 Sarcophilus harrisii 53.82 0.00e+00 869.00
IUUC-Sar-113624 Sorex araneus 45.45 1.00e-55 211.00
IUUC-Ssc-116353 Sus scrofa 55.57 0.00e+00 920.00
IUUC-Tgu-116971 Taeniopygia guttata 57.39 0.00e+00 919.00
IUUC-Tru-117932 Takifugu rubripes 52.44 2.00e-166 580.00
IUUC-Tsy-119185 Tarsius syrichta 54.63 0.00e+00 651.00
IUUC-Tni-119842 Tetraodon nigroviridis 70.31 6.00e-132 464.00
IUUC-Tbe-127281 Tupaia belangeri 45.15 2.00e-86 314.00
IUUC-Ttr-128177 Tursiops truncatus 60.95 0.00e+00 793.00
IUUC-Vpa-130031 Vicugna pacos 56.66 0.00e+00 940.00
IUUC-Xtr-132949 Xenopus tropicalis 56.13 0.00e+00 906.00
Created Date 25-Jun-2017

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