iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Zma-135509

UUCD1 version

UUC-ZeM-01008

Ensembl Protein ID

Zm00001d022058_T001

UniProt Accession

B4FCB3; B4FCB3_MAIZE

Genbank Protein ID

ACF79756.1; ONM59437.1

Protein Name

Ribosome biogenesis protein WDR12 homolog

Genbank Nucleotide ID

BT034751; CM007650

Gene Name

ZEAMMB73_Zm00001d022058

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d022058	Zm00001d022058_T001	Zm00001d022058_T001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-36	123.2	358	392
UBD/Beta-Prp	2.90e-44	153.4	200	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           H++++t++++  s+  +lvs+s Dg++++WDlrt 
   Q: 358  HSSWITACKWhpSScFHLVSSSFDGKVMLWDLRTA 392
           ***********744688***************996 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdls...........................tgkcvhtlkghedsvlslsfspsgdklv 110
           l gh+a v++++ +p+g++l +gs D+tik+w ++                            g+ ++tl gh++ v+++++ + ++++ 
   Q: 200  LRGHTASVKSISADPSGDMLCSGSWDGTIKLWAVEgsddddavslkkrrmnsdssgpeesqlEGSATSTLLGHTQGVTAVTWPE-RKTIY 288
           679*****************************888888999999**************************************88.***** PP
   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtl..tgghtdsvyslsfdsng.kel 195
           s+s+d  +r wd++t ++    +    ++ nc+   ++g +l+++G+ D ++r+Wd  k g+l   +  ++ h + ++  ++++++ ++l
   Q: 289  SASWDHSVRQWDVQTVKETW--NMFCGKALNCLDCGGEGsSLIAAGGSDPVLRVWDPrKPGTLAPVFqfSS-HSSWITACKWHPSScFHL 375
           *****************995..7777788***************************965566666665477.*************9**** PP
   S: 196  vsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsi 246
           vs s dg+v lwdl+t   + ++  h+d v++ + + +++ ++sg++D  +
   Q: 376  VSSSFDGKVMLWDLRTAWPLASVDSHEDKVLCADWW-KGDSVISGGADSKL 425
           ************************************.99999999999876 PP

Organism

Zea mays

Functional Description
(View)

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Protein Sequence
(Fasta)

MEDDPSRQVR VRFVTKLPPP LRTPPAAIAV PADLTRMGLS EIVNSLLAAA EPDHQSQPFD 60
FIVQGELVRL PLQEFLLAKG ISAERVLELE YVRAVAPRKQ EEPCPHDDWV SAVDGSNPGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCGTTCGA AATCCCCAAA GGCCAAAACC CTCCTCCGAA CCCTTCCCGC CGCCGCCACC 60
CCCACCCCGA CCGGCACCAC CACCTCCTAG CTCCACCACC GTCCGCCGTC GCCGCGATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08154--NLE
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0009506--C:plasmodesma
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

KEGG

zma:100192696

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000532	Aegilops tauschii	83.41	0.00e+00	756.00
IUUC-Aml-001997	Ailuropoda melanoleuca	34.75	1.00e-55	210.00
IUUC-Atr-002544	Amborella trichopoda	62.73	8.00e-159	552.00
IUUC-Apl-003981	Anas platyrhynchos	34.40	1.00e-55	209.00
IUUC-Aca-004370	Anolis carolinensis	34.44	4.00e-63	234.00
IUUC-Aly-006455	Arabidopsis lyrata	62.73	1.00e-164	572.00
IUUC-Ath-006669	Arabidopsis thaliana	62.04	2.00e-159	554.00
IUUC-Ago-007864	Ashbya gossypii	31.25	2.00e-49	189.00
IUUC-Acl-008177	Aspergillus clavatus	29.79	1.00e-40	160.00
IUUC-Afl-008617	Aspergillus flavus	29.67	3.00e-38	152.00
IUUC-Afu-008752	Aspergillus fumigatus	29.31	6.00e-36	144.00
IUUC-Ani-009136	Aspergillus nidulans	29.56	3.00e-39	155.00
IUUC-Ang-009701	Aspergillus niger	29.19	4.00e-36	145.00
IUUC-Aor-009884	Aspergillus oryzae	29.67	2.00e-38	153.00
IUUC-Ame-011432	Astyanax mexicanus	33.81	8.00e-64	237.00
IUUC-Bgr-012218	Blumeria graminis	30.30	3.00e-39	155.00
IUUC-Bta-012829	Bos taurus	33.57	6.00e-57	214.00
IUUC-Bci-013953	Botrytis cinerea	29.15	2.00e-36	146.00
IUUC-Bdi-014351	Brachypodium distachyon	84.49	0.00e+00	736.00
IUUC-Bol-016514	Brassica oleracea	63.11	2.00e-155	541.00
IUUC-Bra-016988	Brassica rapa	63.11	6.00e-156	543.00
IUUC-Cel-018569	Caenorhabditis elegans	24.94	1.00e-28	120.00
IUUC-Cja-019468	Callithrix jacchus	34.05	2.00e-54	206.00
IUUC-Cfa-020471	Canis familiaris	33.81	4.00e-54	204.00
IUUC-Cpo-022260	Cavia porcellus	35.00	7.00e-57	214.00
IUUC-Cre-022614	Chlamydomonas reinhardtii	39.05	3.00e-63	235.00
IUUC-Csa-023989	Chlorocebus sabaeus	33.81	2.00e-54	206.00
IUUC-Cho-024426	Choloepus hoffmanni	32.80	2.00e-40	159.00
IUUC-Cin-025789	Ciona intestinalis	31.20	7.00e-52	197.00
IUUC-Cne-027063	Cryptococcus neoformans	27.74	1.00e-27	117.00
IUUC-Dre-027907	Danio rerio	34.05	7.00e-64	237.00
IUUC-Dno-029225	Dasypus novemcinctus	34.05	7.00e-57	214.00
IUUC-Dor-031082	Dipodomys ordii	30.71	5.00e-26	111.00
IUUC-Dse-031308	Dothistroma septosporum	32.04	7.00e-48	184.00
IUUC-Dme-032189	Drosophila melanogaster	29.98	6.00e-46	177.00
IUUC-Ete-032247	Echinops telfairi	31.84	7.00e-50	191.00
IUUC-Eca-034285	Equus caballus	33.57	9.00e-56	210.00
IUUC-Eeu-035322	Erinaceus europaeus	29.46	2.00e-46	179.00
IUUC-Fca-036114	Felis catus	33.81	4.00e-56	211.00
IUUC-Fal-036891	Ficedula albicollis	33.73	6.00e-49	187.00
IUUC-Fox-037965	Fusarium oxysporum	28.31	4.00e-33	135.00
IUUC-Fso-038244	Fusarium solani	28.28	1.00e-34	140.00
IUUC-Gmo-039040	Gadus morhua	34.05	2.00e-65	242.00
IUUC-Ggr-040093	Gaeumannomyces graminis	24.58	2.00e-25	110.00
IUUC-Gga-040610	Gallus gallus	34.29	1.00e-61	229.00
IUUC-Gac-042117	Gasterosteus aculeatus	34.29	1.00e-64	239.00
IUUC-Gma-043756	Glycine max	63.64	1.00e-164	572.00
IUUC-Ggo-045179	Gorilla gorilla	33.57	3.00e-54	205.00
IUUC-Hsa-046114	Homo sapiens	33.81	2.00e-54	206.00
IUUC-Hvu-047331	Hordeum vulgare	83.17	0.00e+00	665.00
IUUC-Itr-048275	Ictidomys tridecemlineatus	34.29	3.00e-57	215.00
IUUC-Kpa-049304	Komagataella pastoris	29.07	1.00e-44	173.00
IUUC-Lch-050655	Latimeria chalumnae	30.41	2.00e-40	159.00
IUUC-Lpe-051675	Leersia perrieri	83.29	0.00e+00	734.00
IUUC-Loc-052868	Lepisosteus oculatus	33.57	6.00e-63	234.00
IUUC-Lma-053258	Leptosphaeria maculans	30.88	6.00e-41	162.00
IUUC-Laf-053993	Loxodonta africana	33.41	3.00e-56	211.00
IUUC-Mcc-055128	Macaca mulatta	27.32	2.00e-32	132.00
IUUC-Meu-056501	Macropus eugenii	34.12	3.00e-47	181.00
IUUC-Mor-057114	Magnaporthe oryzae	28.40	1.00e-36	146.00
IUUC-Mpo-057463	Magnaporthe poae	33.53	7.00e-18	83.20
IUUC-Mtr-058367	Medicago truncatula	61.31	3.00e-156	544.00
IUUC-Mla-059107	Melampsora laricipopulina	26.82	2.00e-40	159.00
IUUC-Mga-059745	Meleagris gallopavo	34.58	2.00e-59	222.00
IUUC-Mvi-060362	Microbotryum violaceum	24.84	5.00e-30	125.00
IUUC-Mdo-062257	Monodelphis domestica	34.05	5.00e-62	231.00
IUUC-Mmu-063546	Mus musculus	34.05	4.00e-57	214.00
IUUC-Mac-065540	Musa acuminata	69.88	0.00e+00	626.00
IUUC-Mpu-066284	Mustela putorius furo	33.81	1.00e-56	213.00
IUUC-Mlu-067241	Myotis lucifugus	33.81	6.00e-57	214.00
IUUC-Nfi-068260	Neosartorya fischeri	29.19	1.00e-38	154.00
IUUC-Ncr-068719	Neurospora crassa	30.40	1.00e-33	137.00
IUUC-Nle-068981	Nomascus leucogenys	34.05	7.00e-53	200.00
IUUC-Opr-071218	Ochotona princeps	31.85	5.00e-51	194.00
IUUC-Ont-071646	Oreochromis niloticus	34.52	6.00e-60	224.00
IUUC-Oan-073453	Ornithorhynchus anatinus	33.57	4.00e-65	241.00
IUUC-Ocu-074008	Oryctolagus cuniculus	34.29	1.00e-57	216.00
IUUC-Oba-075712	Oryza barthii	71.99	1.00e-175	608.00
IUUC-Obr-076721	Oryza brachyantha	81.71	0.00e+00	731.00
IUUC-Ogl-077229	Oryza glaberrima	83.33	0.00e+00	743.00
IUUC-Ogu-078977	Oryza glumaepatula	72.45	9.00e-177	612.00
IUUC-Oin-079683	Oryza indica	83.56	0.00e+00	744.00
IUUC-Olo-080291	Oryza longistaminata	73.03	7.00e-125	439.00
IUUC-Ome-081834	Oryza meridionalis	83.45	0.00e+00	738.00
IUUC-Oni-082507	Oryza nivara	81.25	0.00e+00	710.00
IUUC-Opu-083396	Oryza punctata	82.64	0.00e+00	736.00
IUUC-Oru-085220	Oryza rufipogon	81.48	0.00e+00	712.00
IUUC-Osa-085767	Oryza sativa	83.56	0.00e+00	744.00
IUUC-Ola-087420	Oryzias latipes	34.84	2.00e-66	245.00
IUUC-Olu-087740	Ostreococcus lucimarinus	33.79	4.00e-63	234.00
IUUC-Oga-088264	Otolemur garnettii	32.86	4.00e-53	201.00
IUUC-Oar-089335	Ovis aries	33.33	5.00e-57	214.00
IUUC-Ptr-091320	Pan troglodytes	33.81	2.00e-54	206.00
IUUC-Pan-092833	Papio anubis	33.57	3.00e-54	205.00
IUUC-Psi-093504	Pelodiscus sinensis	32.54	2.00e-55	209.00
IUUC-Pma-094189	Petromyzon marinus	33.81	5.00e-61	227.00
IUUC-Pno-094929	Phaeosphaeria nodorum	28.42	4.00e-38	151.00
IUUC-Ppa-095429	Physcomitrella patens	50.93	5.00e-126	443.00
IUUC-Pfo-096337	Poecilia formosa	35.24	7.00e-66	244.00
IUUC-Pab-097571	Pongo abelii	33.81	2.00e-54	206.00
IUUC-Pop-099977	Populus trichocarpa	65.59	1.00e-168	585.00
IUUC-Pca-100394	Procavia capensis	31.84	3.00e-44	172.00
IUUC-Ppe-101848	Prunus persica	60.42	2.00e-160	558.00
IUUC-Pva-102921	Pteropus vampyrus	30.97	2.00e-23	102.00
IUUC-Pgr-103637	Puccinia graminis	27.39	5.00e-37	148.00
IUUC-Ptt-103781	Puccinia triticina	26.48	2.00e-35	142.00
IUUC-Pte-104135	Pyrenophora teres	29.61	4.00e-40	160.00
IUUC-Pyt-104609	Pyrenophora triticirepentis	29.09	6.00e-41	161.00
IUUC-Rno-105114	Rattus norvegicus	34.29	4.00e-57	214.00
IUUC-Sce-106401	Saccharomyces cerevisiae	28.31	4.00e-44	172.00
IUUC-Sha-107122	Sarcophilus harrisii	34.04	7.00e-61	227.00
IUUC-Sja-107766	Schizosaccharomyces japonicus	27.90	7.00e-36	144.00
IUUC-Spo-108134	Schizosaccharomyces pombe	26.92	1.00e-35	143.00
IUUC-Ssl-108398	Sclerotinia sclerotiorum	28.31	3.00e-41	162.00
IUUC-Smo-108720	Selaginella moellendorffii	49.41	5.00e-120	423.00
IUUC-Sit-110354	Setaria italica	90.34	0.00e+00	806.00
IUUC-Sly-111023	Solanum lycopersicum	57.08	2.00e-151	528.00
IUUC-Stu-112778	Solanum tuberosum	63.28	2.00e-160	557.00
IUUC-Sar-113596	Sorex araneus	30.83	2.00e-42	166.00
IUUC-Sbi-114193	Sorghum bicolor	94.70	0.00e+00	810.00
IUUC-Sre-115002	Sporisorium reilianum	30.22	1.00e-20	94.00
IUUC-Ssc-116066	Sus scrofa	33.81	1.00e-56	213.00
IUUC-Tgu-117048	Taeniopygia guttata	34.13	6.00e-55	207.00
IUUC-Tni-119820	Tetraodon nigroviridis	35.71	9.00e-64	236.00
IUUC-Tca-121605	Theobroma cacao	66.05	3.00e-172	597.00
IUUC-Tre-121947	Trichoderma reesei	27.38	8.00e-36	144.00
IUUC-Tvi-122481	Trichoderma virens	27.02	2.00e-35	143.00
IUUC-Tae-123504	Triticum aestivum	83.41	0.00e+00	756.00
IUUC-Tur-126586	Triticum urartu	83.42	0.00e+00	694.00
IUUC-Tme-126900	Tuber melanosporum	32.28	3.00e-52	198.00
IUUC-Tbe-127736	Tupaia belangeri	35.71	1.00e-21	97.10
IUUC-Ttr-129041	Tursiops truncatus	29.52	1.00e-38	153.00
IUUC-Uma-129628	Ustilago maydis	24.70	1.00e-12	67.40
IUUC-Vpa-130260	Vicugna pacos	33.81	1.00e-56	213.00
IUUC-Vvi-131009	Vitis vinifera	66.74	3.00e-177	614.00
IUUC-Xtr-132083	Xenopus tropicalis	34.52	5.00e-59	221.00
IUUC-Xma-133094	Xiphophorus maculatus	33.65	2.00e-64	238.00
IUUC-Yli-134531	Yarrowia lipolytica	26.58	8.00e-35	140.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence