iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022444

Ensembl Protein ID

ENSCPOP00000001639.2

UniProt Accession

H0UX39; H0UX39_CAVPO

Genbank Protein ID

ENSCPOP00000001639

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02017958

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000001811.3	ENSCPOT00000001832.2	ENSCPOP00000001639.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-31	105.4	1542	1576
UBD/Beta-Prp	1.80e-41	142.2	1409	1612

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g+ikvW+++ ++
   Q: 1542 HKDWVCALAFvPGrPMLLSACRAGVIKVWNVDNFT 1576
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee... 131
            e +++++ +sp+g +++ ++  +++++w+l+ ++++ +l+gh   v++l++ +  ++ d +v+Gs+d +++++  + g+c+     
   Q: 1409 GEHQINQIALSPSG-TMLYVAAGNAVRIWELNRFQPIGKLTGHIGPVMCLTVTQtaNQhDLVVTGSKDHYVKMF--QLGECVTGtig 1492
           56789********9.9999**********************************999555***************..66778866789 PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
               ++ +h + + c+++++  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++ + + 
   Q: 1493 pthnFEPPHYDGIECLAIQG--DILFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGVIKVWNVDNFTP 1577
           9999999************9..9*************************999************************************ PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           + + +gh+++++ + +   ++++ ++ssD  +++W++
   Q: 1578 IGEIKGHDSPINAICTN--SKHIFTASSDCRVKLWNY 1612
           ************77777..****************96 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

QGSSCLGRIR PQLSKEKIEG CHICTSVTPG EPQVLLGKDK AFTYDFVFDL DTWQEQIYTT 60
CVNKLIEGCF EGYNATVLAY GQTGAGKTYT MGTGFDMTTS EEEQGIIPRA IAHLFGGIAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGTTCTT CCTGTCTTGG CAGGATCCGG CCCCAACTGT CAAAGGAGAA GATTGAGGGC 60
TGTCACATCT GTACCTCTGT CACCCCAGGG GAGCCTCAGG TCCTGCTGGG GAAGGACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	93.30	0.00e+00	2775.00
IUUC-Apl-003204	Anas platyrhynchos	74.76	0.00e+00	1558.00
IUUC-Aca-004506	Anolis carolinensis	82.56	0.00e+00	1635.00
IUUC-Bta-013185	Bos taurus	72.78	0.00e+00	2092.00
IUUC-Cja-018844	Callithrix jacchus	91.79	0.00e+00	2781.00
IUUC-Cfa-021187	Canis familiaris	93.71	0.00e+00	2826.00
IUUC-Csa-023852	Chlorocebus sabaeus	94.02	0.00e+00	2846.00
IUUC-Dre-027839	Danio rerio	71.69	0.00e+00	2244.00
IUUC-Dno-030058	Dasypus novemcinctus	90.90	0.00e+00	2758.00
IUUC-Dor-030673	Dipodomys ordii	89.73	0.00e+00	2635.00
IUUC-Ete-032705	Echinops telfairi	82.46	0.00e+00	880.00
IUUC-Eca-033885	Equus caballus	92.98	0.00e+00	2773.00
IUUC-Eeu-035338	Erinaceus europaeus	79.38	0.00e+00	2160.00
IUUC-Fca-035388	Felis catus	93.98	0.00e+00	2663.00
IUUC-Fal-037044	Ficedula albicollis	85.71	0.00e+00	2683.00
IUUC-Gmo-039034	Gadus morhua	68.46	0.00e+00	1264.00
IUUC-Gac-041328	Gasterosteus aculeatus	72.11	0.00e+00	2267.00
IUUC-Ggo-045392	Gorilla gorilla	93.56	0.00e+00	2828.00
IUUC-Hsa-046713	Homo sapiens	94.08	0.00e+00	2847.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	97.87	0.00e+00	1697.00
IUUC-Loc-052703	Lepisosteus oculatus	78.92	0.00e+00	2460.00
IUUC-Laf-054193	Loxodonta africana	84.57	0.00e+00	2492.00
IUUC-Mcc-055484	Macaca mulatta	92.86	0.00e+00	2825.00
IUUC-Meu-056278	Macropus eugenii	85.89	0.00e+00	1201.00
IUUC-Mga-059816	Meleagris gallopavo	83.52	0.00e+00	2553.00
IUUC-Mmr-061071	Microcebus murinus	91.05	0.00e+00	2754.00
IUUC-Mdo-062845	Monodelphis domestica	92.13	0.00e+00	1749.00
IUUC-Mmu-063967	Mus musculus	93.23	0.00e+00	2780.00
IUUC-Mpu-066448	Mustela putorius furo	92.31	0.00e+00	2815.00
IUUC-Nle-070037	Nomascus leucogenys	96.34	0.00e+00	1853.00
IUUC-Opr-070325	Ochotona princeps	89.77	0.00e+00	2625.00
IUUC-Ont-071851	Oreochromis niloticus	72.06	0.00e+00	2277.00
IUUC-Oan-073615	Ornithorhynchus anatinus	88.57	0.00e+00	2530.00
IUUC-Ocu-073855	Oryctolagus cuniculus	93.11	0.00e+00	2783.00
IUUC-Oga-088171	Otolemur garnettii	92.59	0.00e+00	2779.00
IUUC-Oar-089693	Ovis aries	77.77	0.00e+00	1228.00
IUUC-Ptr-090535	Pan troglodytes	95.54	0.00e+00	1813.00
IUUC-Pan-091917	Papio anubis	93.70	0.00e+00	2613.00
IUUC-Psi-093752	Pelodiscus sinensis	77.82	0.00e+00	1399.00
IUUC-Pab-098441	Pongo abelii	94.63	0.00e+00	2858.00
IUUC-Pca-100781	Procavia capensis	95.16	0.00e+00	901.00
IUUC-Pva-103099	Pteropus vampyrus	90.75	0.00e+00	1348.00
IUUC-Rno-105872	Rattus norvegicus	94.27	0.00e+00	2829.00
IUUC-Sha-107097	Sarcophilus harrisii	89.84	0.00e+00	2645.00
IUUC-Ssc-115638	Sus scrofa	92.29	0.00e+00	2444.00
IUUC-Tgu-116504	Taeniopygia guttata	84.27	0.00e+00	1685.00
IUUC-Tru-118242	Takifugu rubripes	72.22	0.00e+00	2286.00
IUUC-Ttr-128824	Tursiops truncatus	89.58	0.00e+00	2245.00
IUUC-Xtr-131798	Xenopus tropicalis	65.73	0.00e+00	1182.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence