iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062504

Ensembl Protein ID

ENSMODP00000036832.2

UniProt Accession

F6V8G1; F6V8G1_MONDO

Protein Name

Uncharacterized protein

Gene Name

GRAP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008992.3	ENSMODT00000038427.2	ENSMODP00000036832.2
ENSMODG00000008992.3	ENSMODT00000011429.3	ENSMODP00000011212.3
ENSMODG00000008992.3	ENSMODT00000011433.3	ENSMODP00000011216.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.40e-28	98.0	336	387

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++lyd+ea+++deL +  G+vv+v+  ++ +  W+ g   l+ + GlfP+n+v+ l
   Q: 336  RALYDFEAEEEDELGFCTGEVVEVL--DSSNPSWWTG--RLHSRLGLFPANYVTPL 387
           79***********************..999*******..8*************976 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MQENVFLTRN SPLPTLEFQE QSDGTLYGLV QAPQSPAAGQ MPLSRQKGLI AALSLFPQRR 60
MEAVAKFDFN ASGEDELSFH TGDVLKILSS QDEWFKAELG SQEGYVPKNF IDIQFPSWFH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCAGCCT TTGGGGGAAC CCCTGGAATG CAGGAAAATG TCTTCCTGAC CAGAAACAGT 60
CCCCTTCCCA CTCTGGAGTT CCAGGAACAG TCAGATGGCA CTCTCTATGG ACTGGTCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005768--C:endosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001994	Ailuropoda melanoleuca	70.78	1.00e-128	452.00
IUUC-Apl-003684	Anas platyrhynchos	59.94	3.00e-104	371.00
IUUC-Aca-005371	Anolis carolinensis	53.01	2.00e-91	328.00
IUUC-Ame-011392	Astyanax mexicanus	44.38	2.00e-69	255.00
IUUC-Bta-013508	Bos taurus	69.28	3.00e-126	444.00
IUUC-Bci-013708	Botrytis cinerea	44.44	2.00e-09	58.50
IUUC-Cja-019613	Callithrix jacchus	57.80	2.00e-45	174.00
IUUC-Cfa-020290	Canis familiaris	70.48	2.00e-128	451.00
IUUC-Cpo-022534	Cavia porcellus	69.58	1.00e-126	446.00
IUUC-Csa-023438	Chlorocebus sabaeus	72.89	4.00e-128	451.00
IUUC-Cho-024466	Choloepus hoffmanni	51.65	8.00e-64	236.00
IUUC-Dre-027927	Danio rerio	46.77	1.00e-75	276.00
IUUC-Dno-029894	Dasypus novemcinctus	68.67	3.00e-126	444.00
IUUC-Dor-030493	Dipodomys ordii	85.62	3.00e-74	271.00
IUUC-Ete-032335	Echinops telfairi	63.55	4.00e-103	367.00
IUUC-Eca-033750	Equus caballus	70.78	4.00e-130	457.00
IUUC-Eeu-034884	Erinaceus europaeus	57.53	2.00e-85	309.00
IUUC-Fca-036001	Felis catus	70.48	9.00e-128	449.00
IUUC-Fal-036692	Ficedula albicollis	59.52	2.00e-104	372.00
IUUC-Gmo-039524	Gadus morhua	66.89	1.00e-55	209.00
IUUC-Gac-041301	Gasterosteus aculeatus	59.76	2.00e-58	219.00
IUUC-Ggo-045424	Gorilla gorilla	72.29	3.00e-127	447.00
IUUC-Hsa-045808	Homo sapiens	72.89	2.00e-128	451.00
IUUC-Itr-048000	Ictidomys tridecemlineatus	71.82	2.00e-126	445.00
IUUC-Lch-049610	Latimeria chalumnae	64.94	6.00e-53	201.00
IUUC-Loc-052925	Lepisosteus oculatus	46.71	6.00e-78	283.00
IUUC-Laf-054004	Loxodonta africana	71.69	6.00e-130	456.00
IUUC-Mcc-055020	Macaca mulatta	72.89	2.00e-128	451.00
IUUC-Meu-056169	Macropus eugenii	81.44	9.00e-151	526.00
IUUC-Mga-059483	Meleagris gallopavo	61.13	8.00e-109	386.00
IUUC-Mmr-061755	Microcebus murinus	72.59	2.00e-129	455.00
IUUC-Mmu-063557	Mus musculus	69.70	8.00e-127	446.00
IUUC-Mpu-066852	Mustela putorius furo	70.18	2.00e-127	448.00
IUUC-Mlu-067510	Myotis lucifugus	70.36	4.00e-128	450.00
IUUC-Nle-069691	Nomascus leucogenys	73.19	9.00e-130	456.00
IUUC-Opr-070271	Ochotona princeps	67.77	2.00e-122	431.00
IUUC-Ont-072651	Oreochromis niloticus	41.28	2.00e-66	245.00
IUUC-Oan-073183	Ornithorhynchus anatinus	69.07	6.00e-121	426.00
IUUC-Ocu-074899	Oryctolagus cuniculus	61.08	3.00e-107	381.00
IUUC-Ola-086462	Oryzias latipes	45.51	5.00e-76	277.00
IUUC-Oga-088553	Otolemur garnettii	71.64	5.00e-131	460.00
IUUC-Oar-089572	Ovis aries	70.78	4.00e-131	460.00
IUUC-Ptr-090582	Pan troglodytes	72.89	3.00e-128	451.00
IUUC-Pan-092063	Papio anubis	72.89	2.00e-128	451.00
IUUC-Psi-094056	Pelodiscus sinensis	63.36	9.00e-109	386.00
IUUC-Pfo-096115	Poecilia formosa	44.98	3.00e-73	268.00
IUUC-Pab-098217	Pongo abelii	72.89	4.00e-128	450.00
IUUC-Pca-100838	Procavia capensis	71.08	5.00e-126	443.00
IUUC-Pva-102559	Pteropus vampyrus	68.12	1.00e-97	349.00
IUUC-Rno-105926	Rattus norvegicus	59.58	9.00e-104	369.00
IUUC-Sha-106948	Sarcophilus harrisii	77.95	3.00e-145	507.00
IUUC-Ssc-115605	Sus scrofa	70.78	3.00e-128	451.00
IUUC-Tgu-117211	Taeniopygia guttata	57.74	4.00e-102	364.00
IUUC-Tru-118347	Takifugu rubripes	56.35	2.00e-60	224.00
IUUC-Tsy-119441	Tarsius syrichta	71.08	2.00e-127	448.00
IUUC-Tni-119732	Tetraodon nigroviridis	68.46	5.00e-59	221.00
IUUC-Tbe-127289	Tupaia belangeri	64.62	2.00e-101	362.00
IUUC-Ttr-128961	Tursiops truncatus	63.86	6.00e-116	410.00
IUUC-Vpa-130320	Vicugna pacos	65.96	3.00e-66	244.00
IUUC-Xtr-131814	Xenopus tropicalis	67.32	7.00e-61	227.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence