iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000019995.1	ENSONIT00000025200.1	ENSONIP00000025179.1
ENSONIG00000019995.1	ENSONIT00000025201.1	ENSONIP00000025180.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.50e-36	121.2	1512	1542
UBD/Beta-Prp	4.30e-80	269.5	1376	1683

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+ +v+++af  d  +++++s Dg+++vW+
   Q: 1512 GHKTKVNDVAFsFDeSHFATCSEDGSVRVWS 1542
           8999********5559**************8 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls................t 83
           +t++++   +++l+tg  +g +  wdv+t+ +l + + +e+e+  + +  +   l+tgs+ r +++w+++                +
   Q: 1376 LTALCY-HMDDFLFTGTNRGHVCTWDVRTQRCLMTWEADEGEIGVLLCRGN--RLLTGSNTRWLRLWEVEavqslkaeekgrgvedS 1459
           566666.55677888888999999999999999999999999999988888..6999999999999977755555544444444422 PP
   S: 84   gkcvhtlk...ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlk 167
             + ++l+     +   +s sf+ + d  ++G+   t+   +++ ++ ++ + sgh+  vn v+++ d++ ++++s D+ vr+W+  
   Q: 1460 -GTAVVLEqeiMLDGATVSASFDNTMDMGIVGTTAGTLWYINWSDNSNIR-LVSGHKTKVNDVAFSFDESHFATCSEDGSVRVWSTL 1544
           .2222222122234444445555555666666666666655666666666.88********************************** PP
   S: 168  tgkllrtl..tgghtdsvysls.fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           + +l+ ++    +  d v +    + ++++++ g  dgtv+++ l ++e+ ++l+ h   ++ ++ s n++ ++s+++ g + +   
   Q: 1545 SYELVVQFqvLNQACDCVCWSPfSSADSTYVAGGYSDGTVRIFRLASTEMEMKLHPHHVAISAIQYSANGHVILSAGKNGLVAVSSP 1631
           ********54333445555555334466*********************************************************** PP
   S: 252  rsgdllktlqlhn.ssvisvav.......lsfgdnvlvlgse.dskvniwkl 294
            +g ++++++ h+   ++ +++       +++++n l l+++ d +v +w  
   Q: 1632 VNGATIRVIKDHKgAMITTIQCvneqcknFGLEGNDLWLATSaDRRVSVWTA 1683
           *************866777777677778888889999998888*******85 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAYKDWQHPY VNIFKYVRVE EWKRSAKEGN VSAYTDKTLK CPVFRIRGPV PANSYILLPK 60
NSSQSLGLTG RFFYLLFRPT PGKYFVVHLD VAAGEGQVVR ISFSNMFKEF KSTATWLQFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCCGTCGT GCTGTCGTTG GCAACGGCGG AGGCTGGAGC GGGAAGCAAA TAACAGCTAT 60
GTACGGTGGA ACGAGCTGCT GTTTACACGG TACCGGGAAA ACTGGAAAGC CCCGCATCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	48.69	0.00e+00	956.00
IUUC-Apl-003387	Anas platyrhynchos	52.86	0.00e+00	1751.00
IUUC-Aca-005235	Anolis carolinensis	54.22	0.00e+00	1746.00
IUUC-Ame-011595	Astyanax mexicanus	61.33	0.00e+00	2254.00
IUUC-Bta-012328	Bos taurus	47.60	0.00e+00	1602.00
IUUC-Cja-019058	Callithrix jacchus	48.30	0.00e+00	848.00
IUUC-Cfa-020934	Canis familiaris	47.09	0.00e+00	1563.00
IUUC-Cpo-022025	Cavia porcellus	46.87	0.00e+00	1569.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	29.46	2.00e-74	275.00
IUUC-Csa-023022	Chlorocebus sabaeus	48.80	0.00e+00	962.00
IUUC-Cin-025133	Ciona intestinalis	38.48	0.00e+00	1345.00
IUUC-Csv-025816	Ciona savignyi	36.32	0.00e+00	1139.00
IUUC-Dre-028823	Danio rerio	59.21	0.00e+00	2159.00
IUUC-Dno-029211	Dasypus novemcinctus	51.48	0.00e+00	662.00
IUUC-Dor-030211	Dipodomys ordii	48.51	0.00e+00	952.00
IUUC-Ete-032363	Echinops telfairi	42.91	0.00e+00	649.00
IUUC-Eca-034296	Equus caballus	48.08	0.00e+00	899.00
IUUC-Eeu-035226	Erinaceus europaeus	42.74	1.00e-178	620.00
IUUC-Fca-035384	Felis catus	48.49	0.00e+00	945.00
IUUC-Fal-037660	Ficedula albicollis	52.59	0.00e+00	1765.00
IUUC-Gga-040666	Gallus gallus	52.44	0.00e+00	1279.00
IUUC-Gac-041358	Gasterosteus aculeatus	74.26	0.00e+00	2624.00
IUUC-Ggo-045121	Gorilla gorilla	46.64	0.00e+00	1634.00
IUUC-Hsa-046289	Homo sapiens	46.85	0.00e+00	1600.00
IUUC-Itr-048485	Ictidomys tridecemlineatus	47.94	0.00e+00	1554.00
IUUC-Lch-050009	Latimeria chalumnae	56.54	0.00e+00	2034.00
IUUC-Loc-052629	Lepisosteus oculatus	61.79	0.00e+00	1245.00
IUUC-Mcc-055834	Macaca mulatta	45.25	0.00e+00	865.00
IUUC-Meu-056162	Macropus eugenii	48.77	0.00e+00	654.00
IUUC-Mga-060167	Meleagris gallopavo	50.86	0.00e+00	1648.00
IUUC-Mmr-060761	Microcebus murinus	52.48	6.00e-94	337.00
IUUC-Mdo-061886	Monodelphis domestica	53.89	0.00e+00	1959.00
IUUC-Mmu-063652	Mus musculus	47.12	0.00e+00	1661.00
IUUC-Mlu-068141	Myotis lucifugus	47.39	0.00e+00	1667.00
IUUC-Nle-069133	Nomascus leucogenys	44.34	0.00e+00	1030.00
IUUC-Oan-072833	Ornithorhynchus anatinus	49.20	0.00e+00	914.00
IUUC-Ola-086564	Oryzias latipes	70.24	0.00e+00	2536.00
IUUC-Oga-088919	Otolemur garnettii	47.49	0.00e+00	1379.00
IUUC-Oar-089946	Ovis aries	51.74	0.00e+00	689.00
IUUC-Ptr-090755	Pan troglodytes	47.10	0.00e+00	1337.00
IUUC-Pan-092054	Papio anubis	46.01	0.00e+00	1578.00
IUUC-Psi-093467	Pelodiscus sinensis	56.46	0.00e+00	2033.00
IUUC-Pma-094573	Petromyzon marinus	45.50	0.00e+00	1573.00
IUUC-Pfo-096849	Poecilia formosa	68.52	0.00e+00	2390.00
IUUC-Pab-098320	Pongo abelii	46.09	0.00e+00	1443.00
IUUC-Pca-100172	Procavia capensis	45.22	0.00e+00	867.00
IUUC-Pva-102772	Pteropus vampyrus	49.81	0.00e+00	961.00
IUUC-Rno-105046	Rattus norvegicus	47.78	0.00e+00	1690.00
IUUC-Sha-107094	Sarcophilus harrisii	53.61	0.00e+00	1994.00
IUUC-Ssc-116257	Sus scrofa	46.60	0.00e+00	1575.00
IUUC-Tgu-117323	Taeniopygia guttata	50.14	0.00e+00	1432.00
IUUC-Tru-118717	Takifugu rubripes	68.28	0.00e+00	2463.00
IUUC-Tni-120108	Tetraodon nigroviridis	65.84	0.00e+00	2317.00
IUUC-Ttr-128378	Tursiops truncatus	52.84	0.00e+00	687.00
IUUC-Xtr-131760	Xenopus tropicalis	53.22	0.00e+00	1892.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence