iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054273

UUCD1 version

UUC-LoA-01075

Ensembl Protein ID

ENSLAFP00000006454.4

UniProt Accession

G3T0G3; G3T0G3_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000007676.4	ENSLAFT00000007679.4	ENSLAFP00000006454.4
ENSLAFG00000007676.4	ENSLAFT00000027536.1	ENSLAFP00000023194.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.40e-107	357.4	735	1568

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 735  TGLSNLGNTCFMNSSIQCVSNTQPLTRYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNG 821
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gql+sq+kc++c+++s+r++p
   Q: 822  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDP 906
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 907  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlsdlcglksdqillaevhssniknfpqdnqkirlsvsgfl 993
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 994  cafeipipgspisasspiqtdfssspstngmftlttngdlprpifipngmpntvvpcgteknftngmvnghmpslpdnpftgyiiav 1080
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1081 hrkmmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1167
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1168 cawcpwyrfcrgckidcgddrafignayiavdwdptalhlryqtsqervldehesveqsrraqaepiNLDSCLRAFTSEEELGENEM 1254
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++                         
   Q: 1255 YYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREsFDPSAFLVPrdpalchrkaltpqgdnlceprlp 1339
           ********************************99775..5569******************99999999999999999999999999 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1340 teevkkadaqnsageedvlltkspsslsaniisspkgspsssrksgtscpssknsspnssprtlgrskgrlrlpqigsknklssske 1426
           999999988888888888888888888888888888888888777777777777776666666666666666666666666665555 PP
   S: 268  ......peekqke.........................................................................k 275
                 +     +                                                                         k
   Q: 1427 nldaskE-----NgagqvceltdalsrghmlggsqpelvtpqdhevtlangflyeheacgngysngqpenhseedstddqredirvK 1508
           5555550.....05555555555555555555555555555555556666666666666666666666666666777778888888* PP
   S: 276  kkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
            +Y+L+a+ +HsG l++GHYv+y+kn + kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1509 PIYNLYAISCHSGILGGGHYVTYAKNPNSKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1568
           *************************************************...********985 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGAKESRIGF LSYEEALRRV TDVELKRLKD AFKRTCGLSY YMGQHCFIRE VLGDGVPPKV 60
AEVIYCSFGG TAKGLHFNNL IVGLVLLTRG RDEEKAKYIF SLFSSESGSY VVREEMERML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCGCCA AGGAGTCACG GATCGGATTT CTCAGCTACG AGGAGGCGCT GAGGAGAGGT 60
GAGGGGGAGG GGTCTGGGCG AGCTGCCGGG GAGGCCGGCG ACAGGCAGTC CAGAGGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	96.06	0.00e+00	2615.00
IUUC-Apl-003272	Anas platyrhynchos	83.76	0.00e+00	2669.00
IUUC-Aca-005057	Anolis carolinensis	83.70	0.00e+00	2299.00
IUUC-Ame-010781	Astyanax mexicanus	74.42	0.00e+00	2409.00
IUUC-Bta-013502	Bos taurus	92.22	0.00e+00	2815.00
IUUC-Cja-018754	Callithrix jacchus	95.76	0.00e+00	3064.00
IUUC-Cfa-020526	Canis familiaris	96.47	0.00e+00	3058.00
IUUC-Cpo-021568	Cavia porcellus	90.12	0.00e+00	2728.00
IUUC-Csa-023143	Chlorocebus sabaeus	95.76	0.00e+00	3028.00
IUUC-Cho-024603	Choloepus hoffmanni	62.60	0.00e+00	695.00
IUUC-Cin-025583	Ciona intestinalis	54.87	0.00e+00	868.00
IUUC-Csv-026344	Ciona savignyi	50.19	0.00e+00	760.00
IUUC-Dre-028121	Danio rerio	76.13	0.00e+00	2363.00
IUUC-Dno-029911	Dasypus novemcinctus	95.09	0.00e+00	2994.00
IUUC-Dor-030608	Dipodomys ordii	66.99	0.00e+00	679.00
IUUC-Dme-032094	Drosophila melanogaster	44.83	2.00e-123	437.00
IUUC-Ete-032639	Echinops telfairi	94.18	0.00e+00	1587.00
IUUC-Eca-034253	Equus caballus	96.42	0.00e+00	2996.00
IUUC-Eeu-035084	Erinaceus europaeus	79.94	0.00e+00	1583.00
IUUC-Fca-035474	Felis catus	95.74	0.00e+00	2478.00
IUUC-Fal-036985	Ficedula albicollis	84.63	0.00e+00	2629.00
IUUC-Gmo-039568	Gadus morhua	79.58	0.00e+00	2124.00
IUUC-Gga-040509	Gallus gallus	83.47	0.00e+00	2744.00
IUUC-Gac-041757	Gasterosteus aculeatus	79.88	0.00e+00	2167.00
IUUC-Ggo-044956	Gorilla gorilla	87.14	0.00e+00	1820.00
IUUC-Hsa-046107	Homo sapiens	95.95	0.00e+00	3055.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	94.27	0.00e+00	1198.00
IUUC-Lch-050681	Latimeria chalumnae	77.80	0.00e+00	2392.00
IUUC-Loc-052474	Lepisosteus oculatus	77.38	0.00e+00	2478.00
IUUC-Mcc-054718	Macaca mulatta	95.95	0.00e+00	3061.00
IUUC-Meu-056558	Macropus eugenii	71.96	0.00e+00	1388.00
IUUC-Mga-059892	Meleagris gallopavo	84.63	0.00e+00	2654.00
IUUC-Mmr-060866	Microcebus murinus	94.87	0.00e+00	3078.00
IUUC-Mdo-062607	Monodelphis domestica	91.66	0.00e+00	2952.00
IUUC-Mmu-063797	Mus musculus	94.02	0.00e+00	3075.00
IUUC-Mpu-066121	Mustela putorius furo	96.76	0.00e+00	3123.00
IUUC-Mlu-067581	Myotis lucifugus	94.72	0.00e+00	3053.00
IUUC-Nle-069916	Nomascus leucogenys	93.38	0.00e+00	2916.00
IUUC-Opr-071073	Ochotona princeps	84.30	0.00e+00	1194.00
IUUC-Ont-071310	Oreochromis niloticus	80.66	0.00e+00	2150.00
IUUC-Oan-073356	Ornithorhynchus anatinus	89.35	0.00e+00	2888.00
IUUC-Ocu-074216	Oryctolagus cuniculus	95.51	0.00e+00	3063.00
IUUC-Ola-087434	Oryzias latipes	74.56	0.00e+00	2266.00
IUUC-Oga-089034	Otolemur garnettii	94.51	0.00e+00	2933.00
IUUC-Oar-090369	Ovis aries	96.16	0.00e+00	3063.00
IUUC-Ptr-090605	Pan troglodytes	96.01	0.00e+00	3059.00
IUUC-Pan-092381	Papio anubis	95.72	0.00e+00	2969.00
IUUC-Psi-093819	Pelodiscus sinensis	86.51	0.00e+00	2742.00
IUUC-Pma-094480	Petromyzon marinus	64.03	0.00e+00	1475.00
IUUC-Pfo-096561	Poecilia formosa	79.76	0.00e+00	2118.00
IUUC-Pab-097643	Pongo abelii	93.02	0.00e+00	2936.00
IUUC-Pca-100944	Procavia capensis	77.54	0.00e+00	1047.00
IUUC-Pva-102732	Pteropus vampyrus	85.86	0.00e+00	2667.00
IUUC-Rno-105113	Rattus norvegicus	94.26	0.00e+00	3020.00
IUUC-Sha-107608	Sarcophilus harrisii	84.40	3.00e-175	607.00
IUUC-Sar-113201	Sorex araneus	83.99	0.00e+00	1694.00
IUUC-Ssc-115469	Sus scrofa	93.83	0.00e+00	670.00
IUUC-Tgu-117322	Taeniopygia guttata	86.01	0.00e+00	2777.00
IUUC-Tru-118705	Takifugu rubripes	68.60	0.00e+00	676.00
IUUC-Tsy-119433	Tarsius syrichta	81.49	0.00e+00	1452.00
IUUC-Tni-120631	Tetraodon nigroviridis	80.05	0.00e+00	2083.00
IUUC-Tbe-127553	Tupaia belangeri	89.06	0.00e+00	694.00
IUUC-Ttr-128260	Tursiops truncatus	94.95	0.00e+00	3051.00
IUUC-Vpa-130479	Vicugna pacos	91.17	0.00e+00	2858.00
IUUC-Xtr-132686	Xenopus tropicalis	82.48	0.00e+00	2597.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence