iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036508

Ensembl Protein ID

ENSFCAP00000020786.1

UniProt Accession

M3X2D9; M3X2D9_FELCA

Genbank Protein ID

ENSFCAP00000020786

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02178525

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000029937.1	ENSFCAT00000022443.1	ENSFCAP00000020786.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.00e-117	393.9	5	379

Active Site

Position(s)	Description	Evidence
131	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 48   vDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVvlaldnrearrkvnrlclnarvp 136
           +D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n+ a+++si++++++++Ff++f +V++aldnr+ar++vnr+cl+a+vp
   Q: 5    IDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIIAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVP 93
           8**************************************************************************************** PP
   S: 137  liesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.vlfnklleeeageeevlekldseekeegkdkvks 224
           liesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+wa +lfn+l++ee++++ev++  d++++e+++++ ++
   Q: 94   LIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAkYLFNQLFGEEDADQEVSP--DRADPEASWEPMEA 180
           *************************************************************************..799*********** PP
   S: 225  elksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv..................sfcsnaealqvpekvekdee 294
           e+++++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++                  +  + ++++++p+ ++kd++
   Q: 181  EARARASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWrkrkppvpldwaevqsqgEETNASDQQNEPQLGLKDQQ 269
           ********************************************************************999999*************** PP
   S: 295  vvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgG 378
           v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aanlr++ +++++  ++++ik++agniipaiattnav++G
   Q: 270  VLDVKSYarlfsKSIETLRVNLAEKGDGA---ELIWDKDDPSAMDFVTSAANLRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAG 354
           ***********99***************9...68****************************.************************** PP
   S: 379  laaqEviKvvsgkfeplknfflfda 403
           l+++E +K++sgk ++++++fl+++
   Q: 355  LIVLEGLKILSGKIDQCRTIFLNKQ 379
           *********************9965 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MHLQIDLDTI DVSNLNRQFL FQKKHVGRSK AQVAKESVLQ FYPKANIIAY HDSIMNPDYN 60
VEFFRQFILV MNALDNRAAR NHVNRMCLAA DVPLIESGTA GYLGQVTTIK KGVTECYECH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTGGAGTT TATGCACTTG CAGATTGATC TGGATACTAT CGACGTCAGC AACCTCAACA 60
GGCAGTTTTT GTTTCAAAAG AAACATGTTG GAAGATCAAA GGCCCAGGTA ACTTTGCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	37.48	5.00e-97	348.00
IUUC-Aml-001662	Ailuropoda melanoleuca	99.16	0.00e+00	1214.00
IUUC-Atr-002636	Amborella trichopoda	38.92	2.00e-98	353.00
IUUC-Apl-003369	Anas platyrhynchos	89.39	0.00e+00	1030.00
IUUC-Aca-004490	Anolis carolinensis	83.39	0.00e+00	905.00
IUUC-Aly-006359	Arabidopsis lyrata	40.55	6.00e-91	328.00
IUUC-Ath-007667	Arabidopsis thaliana	40.74	2.00e-94	340.00
IUUC-Ago-007844	Ashbya gossypii	35.20	1.00e-72	267.00
IUUC-Acl-008270	Aspergillus clavatus	42.29	2.00e-92	333.00
IUUC-Afl-008674	Aspergillus flavus	42.37	7.00e-98	351.00
IUUC-Afu-008883	Aspergillus fumigatus	40.32	1.00e-92	334.00
IUUC-Ani-009500	Aspergillus nidulans	43.66	8.00e-102	364.00
IUUC-Ang-009535	Aspergillus niger	42.21	2.00e-96	346.00
IUUC-Aor-010223	Aspergillus oryzae	42.50	9.00e-100	357.00
IUUC-Ate-010282	Aspergillus terreus	42.63	8.00e-77	281.00
IUUC-Ame-011736	Astyanax mexicanus	78.38	0.00e+00	931.00
IUUC-Bgr-012166	Blumeria graminis	40.79	8.00e-85	308.00
IUUC-Bta-012589	Bos taurus	98.15	0.00e+00	1211.00
IUUC-Bci-013802	Botrytis cinerea	42.30	4.00e-86	312.00
IUUC-Bdi-014697	Brachypodium distachyon	40.08	7.00e-100	357.00
IUUC-Bol-016315	Brassica oleracea	38.31	3.00e-97	349.00
IUUC-Bra-017009	Brassica rapa	39.61	6.00e-98	351.00
IUUC-Cel-018708	Caenorhabditis elegans	45.82	4.00e-119	421.00
IUUC-Cja-019120	Callithrix jacchus	98.15	0.00e+00	1167.00
IUUC-Cfa-021061	Canis familiaris	99.16	0.00e+00	1219.00
IUUC-Cpo-021842	Cavia porcellus	97.14	0.00e+00	1158.00
IUUC-Csa-024104	Chlorocebus sabaeus	98.15	0.00e+00	1132.00
IUUC-Cho-024332	Choloepus hoffmanni	87.91	0.00e+00	837.00
IUUC-Cin-025363	Ciona intestinalis	56.05	0.00e+00	635.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	41.29	7.00e-85	308.00
IUUC-Cne-026888	Cryptococcus neoformans	41.34	2.00e-58	219.00
IUUC-Cme-027315	Cyanidioschyzon merolae	32.87	4.00e-50	192.00
IUUC-Dre-028420	Danio rerio	76.35	0.00e+00	858.00
IUUC-Dno-030041	Dasypus novemcinctus	98.15	0.00e+00	1166.00
IUUC-Dor-031039	Dipodomys ordii	82.03	0.00e+00	649.00
IUUC-Dse-031504	Dothistroma septosporum	44.99	5.00e-85	308.00
IUUC-Dme-031771	Drosophila melanogaster	49.46	1.00e-135	477.00
IUUC-Ete-033037	Echinops telfairi	91.08	0.00e+00	1040.00
IUUC-Eca-033774	Equus caballus	99.33	0.00e+00	1224.00
IUUC-Eeu-035074	Erinaceus europaeus	98.77	0.00e+00	991.00
IUUC-Fal-036813	Ficedula albicollis	86.99	0.00e+00	1023.00
IUUC-Fox-038056	Fusarium oxysporum	42.12	2.00e-90	326.00
IUUC-Fso-038223	Fusarium solani	42.63	8.00e-89	321.00
IUUC-Gmo-038526	Gadus morhua	75.72	0.00e+00	846.00
IUUC-Ggr-039767	Gaeumannomyces graminis	42.23	3.00e-86	313.00
IUUC-Gga-040981	Gallus gallus	89.39	0.00e+00	992.00
IUUC-Gac-041437	Gasterosteus aculeatus	76.82	0.00e+00	868.00
IUUC-Gma-044072	Glycine max	36.58	2.00e-101	363.00
IUUC-Ggo-045358	Gorilla gorilla	94.50	0.00e+00	1076.00
IUUC-Hsa-046068	Homo sapiens	98.32	0.00e+00	1137.00
IUUC-Hvu-047646	Hordeum vulgare	36.83	4.00e-97	348.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	96.97	0.00e+00	1157.00
IUUC-Lch-049565	Latimeria chalumnae	82.41	0.00e+00	979.00
IUUC-Lpe-050884	Leersia perrieri	39.37	7.00e-98	351.00
IUUC-Loc-052493	Lepisosteus oculatus	82.02	0.00e+00	960.00
IUUC-Lma-053117	Leptosphaeria maculans	42.40	7.00e-89	321.00
IUUC-Laf-054518	Loxodonta africana	94.29	0.00e+00	1141.00
IUUC-Mcc-055334	Macaca mulatta	97.98	0.00e+00	1133.00
IUUC-Mor-057137	Magnaporthe oryzae	42.77	4.00e-81	295.00
IUUC-Mpo-057449	Magnaporthe poae	39.63	4.00e-87	315.00
IUUC-Mtr-058045	Medicago truncatula	39.04	2.00e-104	373.00
IUUC-Mla-058864	Melampsora laricipopulina	44.19	1.00e-85	310.00
IUUC-Mga-059422	Meleagris gallopavo	84.64	0.00e+00	927.00
IUUC-Mvi-060536	Microbotryum violaceum	40.37	1.00e-73	270.00
IUUC-Mmr-061161	Microcebus murinus	96.53	0.00e+00	1165.00
IUUC-Mdo-061802	Monodelphis domestica	92.94	0.00e+00	1102.00
IUUC-Mmu-064357	Mus musculus	93.60	0.00e+00	1107.00
IUUC-Mac-065475	Musa acuminata	37.81	2.00e-99	356.00
IUUC-Mpu-066895	Mustela putorius furo	99.66	0.00e+00	1224.00
IUUC-Mlu-067862	Myotis lucifugus	98.49	0.00e+00	1208.00
IUUC-Nfi-068385	Neosartorya fischeri	42.18	9.00e-96	344.00
IUUC-Ncr-068885	Neurospora crassa	39.89	3.00e-91	329.00
IUUC-Nle-069524	Nomascus leucogenys	97.47	0.00e+00	1119.00
IUUC-Opr-071038	Ochotona princeps	97.14	0.00e+00	1159.00
IUUC-Ont-071719	Oreochromis niloticus	77.08	0.00e+00	927.00
IUUC-Oan-072877	Ornithorhynchus anatinus	90.64	0.00e+00	1009.00
IUUC-Ocu-074080	Oryctolagus cuniculus	97.47	0.00e+00	1159.00
IUUC-Oba-075936	Oryza barthii	36.63	6.00e-98	351.00
IUUC-Obr-076841	Oryza brachyantha	36.80	2.00e-99	356.00
IUUC-Ogl-077686	Oryza glaberrima	36.80	3.00e-98	352.00
IUUC-Ogu-078597	Oryza glumaepatula	35.75	1.00e-94	340.00
IUUC-Oin-079791	Oryza indica	36.63	6.00e-98	351.00
IUUC-Olo-081009	Oryza longistaminata	36.47	8.00e-98	350.00
IUUC-Ome-081327	Oryza meridionalis	36.84	4.00e-99	355.00
IUUC-Oni-082334	Oryza nivara	35.92	3.00e-95	342.00
IUUC-Opu-083447	Oryza punctata	36.96	1.00e-99	357.00
IUUC-Oru-084977	Oryza rufipogon	36.59	2.00e-97	349.00
IUUC-Osa-086160	Oryza sativa	41.99	1.00e-84	306.00
IUUC-Ola-087415	Oryzias latipes	76.49	0.00e+00	887.00
IUUC-Olu-087850	Ostreococcus lucimarinus	40.00	1.00e-89	323.00
IUUC-Oga-088434	Otolemur garnettii	97.64	0.00e+00	1165.00
IUUC-Oar-089872	Ovis aries	98.15	0.00e+00	1208.00
IUUC-Ptr-091212	Pan troglodytes	98.32	0.00e+00	1137.00
IUUC-Pan-092708	Papio anubis	98.12	2.00e-117	416.00
IUUC-Psi-093703	Pelodiscus sinensis	90.91	0.00e+00	1058.00
IUUC-Pno-094953	Phaeosphaeria nodorum	44.77	6.00e-93	334.00
IUUC-Ppa-095963	Physcomitrella patens	42.31	4.00e-94	338.00
IUUC-Pfo-097515	Poecilia formosa	76.27	0.00e+00	876.00
IUUC-Pab-097951	Pongo abelii	98.16	0.00e+00	1031.00
IUUC-Pop-099703	Populus trichocarpa	35.19	2.00e-83	303.00
IUUC-Pca-100426	Procavia capensis	94.44	0.00e+00	1165.00
IUUC-Ppe-101152	Prunus persica	37.70	7.00e-99	354.00
IUUC-Pva-102792	Pteropus vampyrus	94.44	0.00e+00	1147.00
IUUC-Pgr-103592	Puccinia graminis	43.11	6.00e-89	322.00
IUUC-Ptt-103805	Puccinia triticina	39.91	3.00e-72	266.00
IUUC-Pte-104215	Pyrenophora teres	43.61	8.00e-99	354.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	44.99	3.00e-97	348.00
IUUC-Rno-106117	Rattus norvegicus	94.44	0.00e+00	1118.00
IUUC-Sce-106177	Saccharomyces cerevisiae	36.66	5.00e-65	242.00
IUUC-Sha-107006	Sarcophilus harrisii	93.29	0.00e+00	1108.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	41.45	9.00e-82	297.00
IUUC-Spo-108020	Schizosaccharomyces pombe	43.95	2.00e-84	306.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	42.15	9.00e-89	321.00
IUUC-Smo-109264	Selaginella moellendorffii	41.67	3.00e-93	335.00
IUUC-Sit-110581	Setaria italica	39.88	9.00e-98	351.00
IUUC-Sly-111870	Solanum lycopersicum	38.29	7.00e-98	351.00
IUUC-Stu-112283	Solanum tuberosum	38.60	1.00e-95	343.00
IUUC-Sar-113432	Sorex araneus	72.44	0.00e+00	782.00
IUUC-Sbi-114075	Sorghum bicolor	37.50	1.00e-97	350.00
IUUC-Sre-114926	Sporisorium reilianum	40.62	3.00e-89	322.00
IUUC-Ssc-116281	Sus scrofa	99.42	2.00e-103	368.00
IUUC-Tgu-117247	Taeniopygia guttata	85.71	0.00e+00	1018.00
IUUC-Tru-118075	Takifugu rubripes	71.77	0.00e+00	838.00
IUUC-Tsy-119398	Tarsius syrichta	80.30	0.00e+00	882.00
IUUC-Tni-120771	Tetraodon nigroviridis	66.28	0.00e+00	753.00
IUUC-Tca-121651	Theobroma cacao	38.18	8.00e-97	347.00
IUUC-Tre-122224	Trichoderma reesei	41.73	2.00e-81	297.00
IUUC-Tvi-122634	Trichoderma virens	41.22	1.00e-81	297.00
IUUC-Tae-125665	Triticum aestivum	39.49	2.00e-94	339.00
IUUC-Tur-126417	Triticum urartu	36.86	2.00e-94	340.00
IUUC-Tme-127016	Tuber melanosporum	42.59	1.00e-84	306.00
IUUC-Tbe-127678	Tupaia belangeri	83.03	0.00e+00	630.00
IUUC-Ttr-128598	Tursiops truncatus	94.44	0.00e+00	1155.00
IUUC-Uma-129612	Ustilago maydis	39.43	7.00e-82	298.00
IUUC-Vda-129811	Verticillium dahliae	41.87	5.00e-90	325.00
IUUC-Vpa-130732	Vicugna pacos	87.63	0.00e+00	1002.00
IUUC-Vvi-130832	Vitis vinifera	39.58	8.00e-96	344.00
IUUC-Xtr-132823	Xenopus tropicalis	76.46	0.00e+00	924.00
IUUC-Xma-133552	Xiphophorus maculatus	76.10	0.00e+00	875.00
IUUC-Yli-134666	Yarrowia lipolytica	36.15	2.00e-61	229.00
IUUC-Zma-135547	Zea mays	36.26	1.00e-96	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence