iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065967

Ensembl Protein ID

ENSMPUP00000016511.1

UniProt Accession

M3YYV1; M3YYV1_MUSPF

Genbank Protein ID

ENSMPUP00000016511

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01018321

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016614.1	ENSMPUT00000016757.1	ENSMPUP00000016511.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.00e-17	61.8	539	586

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 539  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 586
           5788999********************888...***************997 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MKSVQQTFPE GDGSGGSARP GEAVDAASRP PRRRAERFAA SGGAWCGQRV TMKKISLKTF 60
RKSFNLSKSK DETDFMVVPQ PALAGDFGKD EPLFGGCYGK ELAGCDLSGD GEQGGKGRSK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNCGCGCCG GGGGCCCCCC 60
GCGTGTGCCG CGCGTGACGG TGCTGCTGGA TGGGATTTAC TCGCACGGAG GTGGGGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	92.34	0.00e+00	922.00
IUUC-Atr-002940	Amborella trichopoda	29.09	1.20e-02	33.90
IUUC-Apl-004035	Anas platyrhynchos	86.17	0.00e+00	834.00
IUUC-Aca-004782	Anolis carolinensis	83.96	0.00e+00	817.00
IUUC-Ame-011790	Astyanax mexicanus	69.83	0.00e+00	630.00
IUUC-Bta-012579	Bos taurus	95.65	3.00e-108	385.00
IUUC-Bol-015843	Brassica oleracea	28.77	3.30e-02	33.10
IUUC-Cel-018643	Caenorhabditis elegans	33.59	2.00e-12	65.50
IUUC-Cja-019528	Callithrix jacchus	88.97	0.00e+00	922.00
IUUC-Cfa-020678	Canis familiaris	91.59	0.00e+00	921.00
IUUC-Cpo-021947	Cavia porcellus	89.72	0.00e+00	930.00
IUUC-Csa-023935	Chlorocebus sabaeus	89.72	0.00e+00	903.00
IUUC-Cho-024477	Choloepus hoffmanni	86.36	0.00e+00	881.00
IUUC-Cin-025413	Ciona intestinalis	68.24	4.00e-66	244.00
IUUC-Csv-026247	Ciona savignyi	67.47	8.00e-65	240.00
IUUC-Dre-027636	Danio rerio	69.59	2.00e-180	625.00
IUUC-Dno-029048	Dasypus novemcinctus	88.97	0.00e+00	890.00
IUUC-Dor-030401	Dipodomys ordii	87.69	0.00e+00	878.00
IUUC-Ete-033116	Echinops telfairi	49.82	6.00e-60	224.00
IUUC-Eca-033825	Equus caballus	90.84	0.00e+00	887.00
IUUC-Fca-036253	Felis catus	91.59	0.00e+00	853.00
IUUC-Fal-037614	Ficedula albicollis	85.98	0.00e+00	832.00
IUUC-Fox-037898	Fusarium oxysporum	23.29	1.00e-01	30.40
IUUC-Gmo-038928	Gadus morhua	69.00	0.00e+00	645.00
IUUC-Gga-040177	Gallus gallus	85.61	0.00e+00	827.00
IUUC-Gac-042263	Gasterosteus aculeatus	69.00	0.00e+00	666.00
IUUC-Ggo-045288	Gorilla gorilla	89.35	0.00e+00	904.00
IUUC-Hsa-046409	Homo sapiens	89.72	0.00e+00	905.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	90.47	0.00e+00	904.00
IUUC-Lch-050354	Latimeria chalumnae	80.22	0.00e+00	822.00
IUUC-Loc-052319	Lepisosteus oculatus	80.60	0.00e+00	783.00
IUUC-Laf-054070	Loxodonta africana	87.66	0.00e+00	846.00
IUUC-Mcc-055045	Macaca mulatta	89.35	0.00e+00	899.00
IUUC-Meu-055917	Macropus eugenii	86.17	0.00e+00	897.00
IUUC-Mga-059273	Meleagris gallopavo	85.79	0.00e+00	825.00
IUUC-Mmr-061597	Microcebus murinus	90.09	0.00e+00	909.00
IUUC-Mdo-062492	Monodelphis domestica	60.35	7.00e-105	373.00
IUUC-Mmu-063374	Mus musculus	82.16	0.00e+00	810.00
IUUC-Mlu-067532	Myotis lucifugus	89.72	0.00e+00	902.00
IUUC-Nle-069373	Nomascus leucogenys	89.91	0.00e+00	905.00
IUUC-Opr-070873	Ochotona princeps	88.22	0.00e+00	924.00
IUUC-Ont-072498	Oreochromis niloticus	70.53	0.00e+00	699.00
IUUC-Oan-072943	Ornithorhynchus anatinus	70.11	2.00e-91	328.00
IUUC-Ocu-073870	Oryctolagus cuniculus	90.28	0.00e+00	899.00
IUUC-Ola-086866	Oryzias latipes	89.25	1.00e-103	368.00
IUUC-Oga-089057	Otolemur garnettii	88.60	0.00e+00	882.00
IUUC-Oar-089841	Ovis aries	60.63	1.00e-158	553.00
IUUC-Ptr-091054	Pan troglodytes	89.72	0.00e+00	904.00
IUUC-Pma-094253	Petromyzon marinus	82.11	9.00e-92	330.00
IUUC-Pfo-097179	Poecilia formosa	65.43	1.00e-170	592.00
IUUC-Pab-097702	Pongo abelii	89.91	0.00e+00	905.00
IUUC-Pca-100671	Procavia capensis	80.14	1.00e-112	400.00
IUUC-Rno-106044	Rattus norvegicus	79.53	0.00e+00	801.00
IUUC-Sha-107139	Sarcophilus harrisii	84.94	0.00e+00	815.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.30e-02	32.00
IUUC-Sly-111748	Solanum lycopersicum	46.15	2.40e-01	30.00
IUUC-Ssc-115343	Sus scrofa	90.09	0.00e+00	922.00
IUUC-Tgu-117061	Taeniopygia guttata	85.98	0.00e+00	833.00
IUUC-Tni-119829	Tetraodon nigroviridis	67.90	0.00e+00	634.00
IUUC-Tae-123723	Triticum aestivum	27.50	3.70e-02	33.90
IUUC-Ttr-129148	Tursiops truncatus	89.91	0.00e+00	878.00
IUUC-Vpa-130780	Vicugna pacos	88.97	0.00e+00	854.00
IUUC-Vvi-130966	Vitis vinifera	32.69	6.30e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	79.07	0.00e+00	822.00
IUUC-Xma-133904	Xiphophorus maculatus	68.82	0.00e+00	649.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence