iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/BCR/BTB_3-box	86.24	0.00e+00	780.00	IUUC-Hsa-046394

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.

Protein Sequence
(Fasta)

MPPGPEVPVQ VWVDGQLFQA EQSLLVEHCG FFRGLFRSGM REARAAEVRL GALSASGFRT 60
ALRVLRGERP ALAAEDELLQ AVECAAFLQA PALARFLEHS VTSDNCSLLC DAAAAFGLRD 120

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Nucleotide Sequence
(Fasta)

ATGCCCCCAG GCCCCGAGGT CCCAGTGCAG GTGTGGGTGG ACGGTCAACT CTTCCAGGCG 60
GAGCAGTCGC TGCTGGTGGA GCACTGCGGC TTCTTCCGCG GGCTTTTCCG CTCTGGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway

Interpro

IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF01344--Kelch_1

SMART

SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0016567--P:protein ubiquitination

KEGG

mmu:74492

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003699	Anas platyrhynchos	62.20	4.00e-146	511.00
IUUC-Aca-004959	Anolis carolinensis	57.30	2.00e-160	558.00
IUUC-Ame-011920	Astyanax mexicanus	53.32	7.00e-138	483.00
IUUC-Bta-012380	Bos taurus	84.93	0.00e+00	771.00
IUUC-Cja-019736	Callithrix jacchus	86.46	0.00e+00	753.00
IUUC-Cpo-022236	Cavia porcellus	87.50	0.00e+00	711.00
IUUC-Csa-023908	Chlorocebus sabaeus	86.68	0.00e+00	788.00
IUUC-Dre-027361	Danio rerio	52.36	8.00e-136	477.00
IUUC-Dno-030079	Dasypus novemcinctus	87.12	0.00e+00	781.00
IUUC-Ete-032377	Echinops telfairi	82.82	0.00e+00	644.00
IUUC-Eca-034407	Equus caballus	88.84	1.00e-131	462.00
IUUC-Fca-035574	Felis catus	81.62	0.00e+00	728.00
IUUC-Fal-036769	Ficedula albicollis	62.79	3.00e-164	571.00
IUUC-Gmo-038753	Gadus morhua	53.95	2.00e-111	395.00
IUUC-Gga-040678	Gallus gallus	62.53	1.00e-150	526.00
IUUC-Gac-041669	Gasterosteus aculeatus	51.90	2.00e-110	392.00
IUUC-Ggo-044613	Gorilla gorilla	87.19	3.00e-124	437.00
IUUC-Hsa-046394	Homo sapiens	86.24	0.00e+00	750.00
IUUC-Itr-048535	Ictidomys tridecemlineatus	87.99	0.00e+00	795.00
IUUC-Lch-049523	Latimeria chalumnae	54.34	2.00e-141	495.00
IUUC-Loc-052394	Lepisosteus oculatus	55.25	7.00e-138	483.00
IUUC-Laf-053945	Loxodonta africana	75.76	0.00e+00	654.00
IUUC-Mcc-055194	Macaca mulatta	87.12	0.00e+00	764.00
IUUC-Mga-059920	Meleagris gallopavo	57.79	3.00e-140	491.00
IUUC-Mdo-062291	Monodelphis domestica	71.99	0.00e+00	671.00
IUUC-Mpu-066900	Mustela putorius furo	86.94	0.00e+00	757.00
IUUC-Mlu-067679	Myotis lucifugus	81.48	2.00e-105	375.00
IUUC-Ont-071874	Oreochromis niloticus	46.87	4.00e-119	421.00
IUUC-Oan-073257	Ornithorhynchus anatinus	73.27	3.00e-40	156.00
IUUC-Ocu-074692	Oryctolagus cuniculus	75.98	5.00e-171	593.00
IUUC-Ola-086638	Oryzias latipes	51.06	9.00e-121	426.00
IUUC-Oga-088679	Otolemur garnettii	86.76	0.00e+00	749.00
IUUC-Oar-089583	Ovis aries	84.23	1.00e-127	449.00
IUUC-Ptr-091441	Pan troglodytes	82.10	0.00e+00	696.00
IUUC-Pan-092522	Papio anubis	86.24	0.00e+00	759.00
IUUC-Psi-093222	Pelodiscus sinensis	59.64	2.00e-162	565.00
IUUC-Pfo-097348	Poecilia formosa	49.55	5.00e-126	444.00
IUUC-Pab-097889	Pongo abelii	87.83	0.00e+00	690.00
IUUC-Tru-117584	Takifugu rubripes	51.39	1.00e-129	456.00
IUUC-Tni-119886	Tetraodon nigroviridis	51.18	2.00e-115	409.00
IUUC-Xtr-131981	Xenopus tropicalis	54.72	1.00e-134	472.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence