iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020232

UUCD1 version

UUC-CaF-01021

Ensembl Protein ID

ENSCAFP00000012550.3

UniProt Accession

E2R2N1; H9GWG8; E2R2N1_CANLF

Genbank Protein ID

ENSCAFP00000012550

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03010567

Gene Name

LOC100855682

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000030450.1	ENSCAFT00000013563.3	ENSCAFP00000012550.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-75	254.2	81	375

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl+N+gNtCY+N++LQcL+ +++l++++l++++ ++ +     ++ ++l++lq+ +  +         p ++l+ l  +   f+  +q+
   Q: 81   GLQNMGNTCYVNATLQCLTYTEPLASYMLSQQHGTTCR----RQTSCMLCTLQTHLMRV------LCHPGRVLRPLPLLLAAFHRHKQE 159
           9*****************************33333222....34567777777777666......356666666666667779999*** PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+E+l+f+ld++++++                   +d+ ++ +  + ++li++lF+g ++sqi+cl+c+ +ss+ ep ld+sl++ + 
   Q: 160  DAHEYLMFILDAMQQAC-----------------LPEDKLSDPECPQDSTLIQQLFGGYWRSQIQCLHCQGISSTLEPYLDISLDIGDA 231
           *****************.................22333567789999***************************************** PP
   S: 180  eetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctsp 268
           +     s++++Le+ +k+e legen+y+c+kc +k+ a+k l+l++ P+vLil L Rf    +    +k++k+v++p++Ld++++++++
   Q: 232  H-----SVSQALEQLVKPELLEGENAYHCSKCLEKVPASKVLTLHTSPKVLILVLRRF----SDLTGNKMTKEVQYPERLDMQHYLSEQ 311
           *.....9***************************************************....346778********************6 PP
   S: 269  eekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
             +   +  Y L+av+vH G s++sGHY+++vk  +g+W+++dD kV++++ +  l+   + aYvlfY++
   Q: 312  RAG---PLVYVLYAVLVHAGrSCHSGHYFCFVKAGNGQWYKMDDAKVSACDVTCALR---QPAYVLFYMQ 375
           655...9********************************************999999...9*******98 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MEAAHLHPSE EPQFSASPKP QSYWSRRGGA EVHGGPSVPE RTSPASKTLS SPTDPLAPAS 60
AGLPPTKTPL SWKSLSQVGA GLQNMGNTCY VNATLQCLTY TEPLASYMLS QQHGTTCRRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCTG CCCACCTCCA CCCCTCAGAG GAGCCTCAGT TCAGCGCCTC TCCCAAACCC 60
CAGTCATACT GGTCAAGGAG AGGCGGTGCT GAAGTCCACG GAGGACCCTC TGTGCCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006861--HABP4_PAIRBP1-bd
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF04774--HABP4_PAI-RBP1
PF00443--UCH

SMART

SM01233--HABP4_PAI-RBP1

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Eca-034337	Equus caballus	62.53	5.00e-164	570.00
IUUC-Mcc-055436	Macaca mulatta	53.46	1.00e-143	503.00
IUUC-Nle-069473	Nomascus leucogenys	54.16	4.00e-146	511.00
IUUC-Ocu-074058	Oryctolagus cuniculus	52.38	1.00e-133	469.00
IUUC-Pan-092796	Papio anubis	53.70	7.00e-139	487.00
IUUC-Ssc-115538	Sus scrofa	54.59	5.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence