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Tag Content
UUCD2 ID IUUC-Mlu-068223
UUCD1 version UUC-MyL-00788
Ensembl Protein ID ENSMLUP00000016049.2
UniProt Accession G1PX87; G1PX87_MYOLU
Genbank Protein ID ENSMLUP00000016049
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAPE02064470
Gene Name PRPF19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000017597.2 ENSMLUT00000017603.2 ENSMLUP00000016049.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.70e-32 110.1 405 438
E3 activity/RING/U-box 3.20e-15 56.0 3 64
UBD/Beta-Prp 7.90e-54 182.9 247 476
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH++++t++af  ++ +l++++dD ++k+WDlr+
   Q: 405  GHSGPITSIAFseNGYYLATAADDSSVKLWDLRK 438
           8**********976699**************986 PP
   

   E3 activity/RING/U-box
   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqa 67
           ++C+Is+e++++P+v+p s++ y+r+ Iek++a++g+ +P+++qpl+ee+lv+ ++ + +  +
   Q: 3    LICSISNEVPEHPCVSPvSNHIYERRLIEKYIAENGT-DPINNQPLSEEQLVDIKVAHPIRPK 64
           79**********************************9.***************9998877665 PP
   

   UBD/Beta-Prp
   S: 20   pdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
            d++ ++tg++d+ + v+d ++++ l++l+gh ++vt+v f+p++++  ++s D+ti++w++ + +cv+++++he+sv+ ls++++gd+
   Q: 247  ADTNKILTGGADKNVVVFDKSSEQILATLKGHAKKVTSVVFHPSQELVFSASPDATIRIWSVPSASCVQVVRAHESSVTGLSLHATGDY 335
           58899************************************************************************************ PP
   S: 109  lvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelv 196
           l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G+ D+++++Wdlk  + +  + g h ++++s++f++ng +l+
   Q: 336  LLSSSDDQYWAFSDIQTGRVLTKvTDETSGCALTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYLA 423
           *********************997777777799************************************9.****************** PP
   S: 197  sgsldgtvklwdlqtgecvrtlnghtd.nvksvrfspnderlvsgssDgsiri 248
           ++++d++vklwdl++ +  +tl+  ++  vks+ f++ +++l+ g+ D +i+i
   Q: 424  TAADDSSVKLWDLRKLKNFKTLQLDNNfEVKSLIFDQSGTYLALGGTDVQIYI 476
           **************999999999866527*******************99987 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
MSLICSISNE VPEHPCVSPV SNHIYERRLI EKYIAENGTD PINNQPLSEE QLVDIKVAHP 60
IRPKPPSATS IPAILKALQD EWGCAHSSLP LTRGCPQDAV MLHSFTLRQQ LQTTRQELSH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-068223|E3,WD_repeat;E3,U-box;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCCTTGA TCTGCTCCAG TGAGTACCTG CTGCGGCCGA TCGAGGGTCG CAGGAGGCCG 60
GGGAGCTGAG CGGGAGGGGC TGCGGCCGCT GGGGCGCCGG GGCCGGGCGG AGGTGACCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-068223|E3,WD_repeat;E3,U-box;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50231--RICIN_B_LECTIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00504--Ubox
SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0005662--C:DNA replication factor A complex
GO:0005811--C:lipid particle
GO:0016020--C:membrane
GO:0016607--C:nuclear speck
GO:0000974--C:Prp19 complex
GO:0035861--C:site of double-strand break
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0034613--P:cellular protein localization
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0001833--P:inner cell mass cell proliferation
GO:0008610--P:lipid biosynthetic process
GO:0045665--P:negative regulation of neuron differentiation
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0048026--P:positive regulation of mRNA splicing, via spliceosome
GO:0010498--P:proteasomal protein catabolic process
GO:0070534--P:protein K63-linked ubiquitination
GO:0072422--P:signal transduction involved in DNA damage checkpoint
GO:0000245--P:spliceosomal complex assembly
GO:0000244--P:spliceosomal tri-snRNP complex assembly
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000488 Aegilops tauschii 38.75 2.00e-95 344.00
IUUC-Aml-001230 Ailuropoda melanoleuca 92.23 0.00e+00 939.00
IUUC-Atr-002594 Amborella trichopoda 43.20 2.00e-116 412.00
IUUC-Apl-003686 Anas platyrhynchos 88.32 0.00e+00 736.00
IUUC-Aca-005272 Anolis carolinensis 93.45 0.00e+00 981.00
IUUC-Aly-005586 Arabidopsis lyrata 42.48 4.00e-115 408.00
IUUC-Ath-007696 Arabidopsis thaliana 42.78 2.00e-111 395.00
IUUC-Acl-008335 Aspergillus clavatus 34.11 4.00e-65 242.00
IUUC-Afl-008527 Aspergillus flavus 35.99 2.00e-69 256.00
IUUC-Afu-008957 Aspergillus fumigatus 36.35 2.00e-76 280.00
IUUC-Ani-009280 Aspergillus nidulans 35.98 5.00e-64 238.00
IUUC-Ang-009746 Aspergillus niger 34.15 2.00e-63 236.00
IUUC-Aor-009905 Aspergillus oryzae 35.79 5.00e-73 268.00
IUUC-Ate-010412 Aspergillus terreus 35.99 8.00e-62 231.00
IUUC-Ame-011561 Astyanax mexicanus 79.22 9.00e-108 382.00
IUUC-Bgr-012283 Blumeria graminis 31.25 1.00e-52 200.00
IUUC-Bta-013242 Bos taurus 95.18 0.00e+00 992.00
IUUC-Bci-013901 Botrytis cinerea 32.43 3.00e-62 232.00
IUUC-Bdi-014277 Brachypodium distachyon 42.72 3.00e-121 428.00
IUUC-Bol-016207 Brassica oleracea 43.88 3.00e-114 405.00
IUUC-Bra-017902 Brassica rapa 42.29 1.00e-113 403.00
IUUC-Cel-018271 Caenorhabditis elegans 50.48 4.00e-149 521.00
IUUC-Cja-019879 Callithrix jacchus 94.62 0.00e+00 985.00
IUUC-Cfa-020175 Canis familiaris 95.18 0.00e+00 991.00
IUUC-Cpo-022379 Cavia porcellus 94.80 0.00e+00 989.00
IUUC-Cre-022993 Chlamydomonas reinhardtii 38.62 3.00e-95 342.00
IUUC-Csa-023500 Chlorocebus sabaeus 94.99 0.00e+00 991.00
IUUC-Cho-025065 Choloepus hoffmanni 81.60 4.00e-143 500.00
IUUC-Cin-025699 Ciona intestinalis 64.75 2.00e-170 592.00
IUUC-Csv-026128 Ciona savignyi 62.43 0.00e+00 668.00
IUUC-Cgl-026507 Colletotrichum gloeosporioides 31.68 7.00e-62 231.00
IUUC-Cne-026860 Cryptococcus neoformans 36.69 2.00e-91 329.00
IUUC-Dre-028187 Danio rerio 81.92 0.00e+00 850.00
IUUC-Dno-029453 Dasypus novemcinctus 94.80 0.00e+00 989.00
IUUC-Dor-030150 Dipodomys ordii 97.06 5.00e-126 444.00
IUUC-Dse-031220 Dothistroma septosporum 31.10 2.00e-55 209.00
IUUC-Dme-031906 Drosophila melanogaster 63.08 0.00e+00 654.00
IUUC-Ete-033035 Echinops telfairi 83.04 0.00e+00 840.00
IUUC-Eca-033478 Equus caballus 94.99 0.00e+00 989.00
IUUC-Eeu-034974 Erinaceus europaeus 97.87 0.00e+00 671.00
IUUC-Fca-036194 Felis catus 94.39 0.00e+00 981.00
IUUC-Fal-037417 Ficedula albicollis 93.45 0.00e+00 980.00
IUUC-Fox-037922 Fusarium oxysporum 33.33 6.00e-62 231.00
IUUC-Fso-038256 Fusarium solani 33.07 6.00e-63 234.00
IUUC-Gmo-038713 Gadus morhua 82.88 0.00e+00 864.00
IUUC-Ggr-039854 Gaeumannomyces graminis 31.34 2.00e-51 196.00
IUUC-Gga-041143 Gallus gallus 93.64 0.00e+00 981.00
IUUC-Gac-042129 Gasterosteus aculeatus 82.69 0.00e+00 883.00
IUUC-Gma-044273 Glycine max 44.11 1.00e-118 419.00
IUUC-Ggo-045262 Gorilla gorilla 94.99 0.00e+00 991.00
IUUC-Hsa-046036 Homo sapiens 94.99 0.00e+00 991.00
IUUC-Hvu-047442 Hordeum vulgare 41.19 2.00e-65 242.00
IUUC-Itr-048169 Ictidomys tridecemlineatus 94.41 0.00e+00 946.00
IUUC-Lch-050105 Latimeria chalumnae 87.09 0.00e+00 928.00
IUUC-Lpe-050976 Leersia perrieri 43.42 5.00e-117 414.00
IUUC-Loc-052042 Lepisosteus oculatus 72.31 0.00e+00 657.00
IUUC-Lma-053143 Leptosphaeria maculans 32.72 2.00e-60 227.00
IUUC-Laf-053451 Loxodonta africana 95.01 0.00e+00 992.00
IUUC-Mcc-055786 Macaca mulatta 94.99 0.00e+00 991.00
IUUC-Meu-056161 Macropus eugenii 97.51 4.00e-139 488.00
IUUC-Mor-057215 Magnaporthe oryzae 32.31 8.00e-54 204.00
IUUC-Mpo-057419 Magnaporthe poae 30.80 1.00e-47 184.00
IUUC-Mtr-057756 Medicago truncatula 42.83 3.00e-113 401.00
IUUC-Mla-059085 Melampsora laricipopulina 36.75 4.00e-83 301.00
IUUC-Mga-060158 Meleagris gallopavo 89.46 0.00e+00 882.00
IUUC-Mvi-060441 Microbotryum violaceum 36.57 2.00e-75 276.00
IUUC-Mmr-061085 Microcebus murinus 94.99 0.00e+00 991.00
IUUC-Mdo-061804 Monodelphis domestica 95.38 0.00e+00 994.00
IUUC-Mmu-063608 Mus musculus 95.22 0.00e+00 998.00
IUUC-Mac-064972 Musa acuminata 43.74 7.00e-116 410.00
IUUC-Mpu-065700 Mustela putorius furo 95.18 0.00e+00 993.00
IUUC-Nfi-068504 Neosartorya fischeri 35.95 6.00e-76 278.00
IUUC-Ncr-068729 Neurospora crassa 35.16 4.00e-60 225.00
IUUC-Nle-069754 Nomascus leucogenys 94.99 0.00e+00 991.00
IUUC-Opr-070621 Ochotona princeps 91.02 0.00e+00 928.00
IUUC-Ont-071377 Oreochromis niloticus 82.31 0.00e+00 860.00
IUUC-Oan-073498 Ornithorhynchus anatinus 68.55 2.00e-119 421.00
IUUC-Ocu-074182 Oryctolagus cuniculus 94.10 0.00e+00 991.00
IUUC-Oba-075509 Oryza barthii 42.72 3.00e-119 421.00
IUUC-Obr-076480 Oryza brachyantha 43.10 3.00e-120 425.00
IUUC-Ogl-077052 Oryza glaberrima 42.72 3.00e-119 421.00
IUUC-Ogu-078919 Oryza glumaepatula 42.72 3.00e-119 421.00
IUUC-Oin-079357 Oryza indica 42.21 6.00e-113 400.00
IUUC-Olo-080376 Oryza longistaminata 42.43 4.00e-107 381.00
IUUC-Ome-081973 Oryza meridionalis 41.95 5.00e-107 381.00
IUUC-Oni-082849 Oryza nivara 42.91 6.00e-120 424.00
IUUC-Opu-083243 Oryza punctata 42.54 2.00e-118 419.00
IUUC-Oru-084613 Oryza rufipogon 42.99 3.00e-119 421.00
IUUC-Osa-085407 Oryza sativa 42.70 1.00e-118 420.00
IUUC-Ola-086566 Oryzias latipes 81.52 0.00e+00 851.00
IUUC-Olu-087757 Ostreococcus lucimarinus 37.79 4.00e-91 328.00
IUUC-Oga-089010 Otolemur garnettii 90.61 0.00e+00 938.00
IUUC-Oar-089638 Ovis aries 95.18 0.00e+00 992.00
IUUC-Ptr-091141 Pan troglodytes 94.99 0.00e+00 991.00
IUUC-Pan-092662 Papio anubis 94.99 0.00e+00 991.00
IUUC-Psi-093777 Pelodiscus sinensis 97.14 0.00e+00 820.00
IUUC-Pno-095115 Phaeosphaeria nodorum 33.40 2.00e-61 229.00
IUUC-Ppa-095841 Physcomitrella patens 43.15 5.00e-117 414.00
IUUC-Pfo-096390 Poecilia formosa 81.92 0.00e+00 863.00
IUUC-Pab-098250 Pongo abelii 94.50 0.00e+00 926.00
IUUC-Pop-099854 Populus trichocarpa 43.82 5.00e-117 414.00
IUUC-Pca-100553 Procavia capensis 94.41 0.00e+00 981.00
IUUC-Ppe-101383 Prunus persica 42.78 6.00e-111 394.00
IUUC-Pva-102189 Pteropus vampyrus 95.38 0.00e+00 994.00
IUUC-Pgr-103304 Puccinia graminis 35.96 4.00e-81 295.00
IUUC-Ptt-103984 Puccinia triticina 36.46 5.00e-86 311.00
IUUC-Pte-104385 Pyrenophora teres 31.49 1.00e-65 243.00
IUUC-Pyt-104697 Pyrenophora triticirepentis 31.70 1.00e-66 247.00
IUUC-Rno-105581 Rattus norvegicus 94.80 0.00e+00 990.00
IUUC-Sha-107071 Sarcophilus harrisii 94.15 0.00e+00 997.00
IUUC-Sja-107697 Schizosaccharomyces japonicus 29.84 8.00e-32 131.00
IUUC-Spo-108315 Schizosaccharomyces pombe 32.21 2.00e-44 173.00
IUUC-Ssl-108628 Sclerotinia sclerotiorum 33.62 4.00e-61 228.00
IUUC-Smo-109648 Selaginella moellendorffii 43.88 2.00e-119 422.00
IUUC-Sit-109873 Setaria italica 42.96 7.00e-117 414.00
IUUC-Sly-111673 Solanum lycopersicum 43.82 3.00e-110 392.00
IUUC-Stu-112125 Solanum tuberosum 43.69 3.00e-109 388.00
IUUC-Sbi-114696 Sorghum bicolor 41.79 7.00e-107 380.00
IUUC-Sre-115134 Sporisorium reilianum 30.12 2.00e-68 253.00
IUUC-Ssc-116260 Sus scrofa 94.99 0.00e+00 991.00
IUUC-Tgu-116533 Taeniopygia guttata 93.45 0.00e+00 980.00
IUUC-Tru-117800 Takifugu rubripes 81.35 0.00e+00 883.00
IUUC-Tsy-118980 Tarsius syrichta 89.50 0.00e+00 898.00
IUUC-Tni-120334 Tetraodon nigroviridis 79.59 9.00e-173 599.00
IUUC-Tca-121807 Theobroma cacao 42.70 4.00e-117 415.00
IUUC-Tre-121920 Trichoderma reesei 31.76 1.00e-59 224.00
IUUC-Tvi-122294 Trichoderma virens 31.43 9.00e-52 197.00
IUUC-Tae-125713 Triticum aestivum 43.10 6.00e-122 431.00
IUUC-Tur-126664 Triticum urartu 38.87 1.00e-111 397.00
IUUC-Tme-127026 Tuber melanosporum 33.46 7.00e-66 244.00
IUUC-Tbe-127582 Tupaia belangeri 97.57 0.00e+00 668.00
IUUC-Ttr-128313 Tursiops truncatus 94.80 0.00e+00 982.00
IUUC-Uma-129626 Ustilago maydis 32.43 2.00e-71 263.00
IUUC-Vda-129699 Verticillium dahliae 34.08 2.00e-64 239.00
IUUC-Vpa-130593 Vicugna pacos 94.24 0.00e+00 882.00
IUUC-Vvi-131668 Vitis vinifera 42.96 2.00e-116 412.00
IUUC-Xtr-132186 Xenopus tropicalis 83.04 0.00e+00 760.00
IUUC-Xma-133212 Xiphophorus maculatus 81.73 0.00e+00 858.00
IUUC-Yli-134607 Yarrowia lipolytica 52.38 1.00e-38 151.00
IUUC-Zma-135662 Zea mays 44.17 2.00e-119 422.00
Created Date 25-Jun-2017

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