iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Cel-018623

Ensembl Protein ID

F38A6.2a

UniProt Accession

O45487; EMAL_CAEEL

Genbank Protein ID

CAB07379.1

Protein Name

Echinoderm microtubule-associated protein-like elp-1

Genbank Nucleotide ID

Z92833

Gene Name

elp-1; F38A6.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
WBGene00001248	F38A6.2a	F38A6.2a
WBGene00001248	F38A6.2b	F38A6.2b

Annotation

mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-13	50.9	504	536

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           v +++f  + + +v+G  +gti +WD+rt++ +k
   Q: 504  VLSMCFgeN-DQVVTGDSNGTISIWDPRTCKTTK 536
           789999754.899****************99876 PP

Organism

Caenorhabditis elegans

Functional Description
(View)

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

Protein Sequence
(Fasta)

MSISNGWSSS SIISDVLPEE EFEEVEEDEL ILNENDRLKF RVDELEKIVV AQRNEILLLQ 60
SSTVEILRRL QNLEIQDQSR SPTCSGYSSL PRRISGSKSS YTMSPSHAPP RSSHANSKSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAAAATTT GCAAAAATTC TTCAAAAAAA TGTCAATAAG CAATGGTTGG TCGTCGTCGT 60
CAATTATATC CGACGTGCTG CCAGAAGAAG AGTTTGAAGA AGTTGAAGAA GGTAAAAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0005874--C:microtubule
GO:0015630--C:microtubule cytoskeleton
GO:0031594--C:neuromuscular junction
GO:0043025--C:neuronal cell body
GO:0008017--F:microtubule binding

KEGG

cel:CELE_F38A6.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001465	Ailuropoda melanoleuca	29.40	7.00e-83	300.00
IUUC-Apl-004179	Anas platyrhynchos	29.32	3.00e-82	298.00
IUUC-Aca-005316	Anolis carolinensis	29.09	7.00e-75	274.00
IUUC-Ame-011647	Astyanax mexicanus	30.55	2.00e-87	315.00
IUUC-Bta-013457	Bos taurus	29.25	4.00e-83	301.00
IUUC-Cja-018976	Callithrix jacchus	28.87	5.00e-83	301.00
IUUC-Cfa-020344	Canis familiaris	29.55	2.00e-83	302.00
IUUC-Cpo-022426	Cavia porcellus	28.66	1.00e-79	290.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	22.21	6.00e-27	117.00
IUUC-Csa-023355	Chlorocebus sabaeus	29.02	5.00e-83	301.00
IUUC-Cho-024398	Choloepus hoffmanni	36.45	2.00e-54	206.00
IUUC-Cin-025784	Ciona intestinalis	29.51	1.00e-80	293.00
IUUC-Csv-026305	Ciona savignyi	31.12	2.00e-79	289.00
IUUC-Dre-028734	Danio rerio	31.09	4.00e-90	324.00
IUUC-Dno-029055	Dasypus novemcinctus	29.13	1.00e-82	299.00
IUUC-Dor-030628	Dipodomys ordii	29.07	2.00e-82	299.00
IUUC-Dme-032093	Drosophila melanogaster	26.81	7.00e-57	214.00
IUUC-Ete-032548	Echinops telfairi	26.08	1.00e-58	220.00
IUUC-Eca-033255	Equus caballus	29.91	5.00e-84	304.00
IUUC-Eeu-034661	Erinaceus europaeus	34.58	4.00e-31	128.00
IUUC-Fca-035446	Felis catus	28.96	3.00e-84	305.00
IUUC-Fal-036734	Ficedula albicollis	29.28	1.00e-80	293.00
IUUC-Gmo-038689	Gadus morhua	29.84	3.00e-85	308.00
IUUC-Gga-041202	Gallus gallus	29.10	7.00e-81	294.00
IUUC-Gac-042643	Gasterosteus aculeatus	30.24	6.00e-85	307.00
IUUC-Ggo-044828	Gorilla gorilla	29.02	6.00e-83	300.00
IUUC-Hsa-045664	Homo sapiens	29.02	3.00e-83	301.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	28.68	2.00e-75	275.00
IUUC-Lch-050508	Latimeria chalumnae	28.65	1.00e-80	293.00
IUUC-Loc-052823	Lepisosteus oculatus	29.88	8.00e-87	313.00
IUUC-Laf-054189	Loxodonta africana	28.76	8.00e-81	293.00
IUUC-Mcc-055810	Macaca mulatta	28.94	2.00e-82	299.00
IUUC-Meu-056664	Macropus eugenii	30.54	2.00e-82	298.00
IUUC-Mga-059405	Meleagris gallopavo	29.25	1.00e-80	293.00
IUUC-Mmr-061144	Microcebus murinus	28.94	2.00e-82	299.00
IUUC-Mdo-062834	Monodelphis domestica	29.48	1.00e-83	303.00
IUUC-Mmu-063955	Mus musculus	29.02	3.00e-82	298.00
IUUC-Mpu-066240	Mustela putorius furo	28.96	9.00e-84	303.00
IUUC-Mlu-068068	Myotis lucifugus	29.36	9.00e-83	300.00
IUUC-Nle-069783	Nomascus leucogenys	28.72	3.00e-81	295.00
IUUC-Opr-070409	Ochotona princeps	30.58	4.00e-80	291.00
IUUC-Ont-071258	Oreochromis niloticus	30.70	3.00e-87	315.00
IUUC-Oan-073315	Ornithorhynchus anatinus	29.62	1.00e-81	296.00
IUUC-Ocu-074399	Oryctolagus cuniculus	29.25	2.00e-82	299.00
IUUC-Ola-086734	Oryzias latipes	29.17	1.00e-84	306.00
IUUC-Olu-087860	Ostreococcus lucimarinus	24.52	1.00e-37	150.00
IUUC-Oga-089105	Otolemur garnettii	29.17	4.00e-83	301.00
IUUC-Oar-090057	Ovis aries	29.32	1.00e-84	306.00
IUUC-Ptr-091138	Pan troglodytes	28.87	2.00e-82	299.00
IUUC-Pan-091831	Papio anubis	28.96	5.00e-82	298.00
IUUC-Psi-093094	Pelodiscus sinensis	27.62	1.00e-84	306.00
IUUC-Pma-094555	Petromyzon marinus	27.44	6.00e-74	270.00
IUUC-Pfo-096717	Poecilia formosa	30.94	2.00e-88	318.00
IUUC-Pab-097787	Pongo abelii	28.94	9.00e-83	300.00
IUUC-Pca-100221	Procavia capensis	28.40	9.00e-70	257.00
IUUC-Pva-102676	Pteropus vampyrus	28.79	2.00e-78	285.00
IUUC-Rno-105412	Rattus norvegicus	29.10	2.00e-81	295.00
IUUC-Sha-106692	Sarcophilus harrisii	30.39	3.00e-84	305.00
IUUC-Sar-113748	Sorex araneus	24.60	3.00e-49	189.00
IUUC-Ssc-115740	Sus scrofa	28.66	7.00e-80	291.00
IUUC-Tgu-116696	Taeniopygia guttata	28.88	2.00e-81	296.00
IUUC-Tru-117809	Takifugu rubripes	32.59	2.00e-89	322.00
IUUC-Tsy-119142	Tarsius syrichta	32.02	6.00e-71	261.00
IUUC-Tni-120815	Tetraodon nigroviridis	31.50	2.00e-88	318.00
IUUC-Tbe-127916	Tupaia belangeri	24.22	4.00e-48	185.00
IUUC-Ttr-129042	Tursiops truncatus	29.17	4.00e-84	304.00
IUUC-Vpa-130697	Vicugna pacos	27.76	1.00e-70	260.00
IUUC-Xtr-132731	Xenopus tropicalis	27.66	8.00e-86	310.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence