iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011927

Ensembl Protein ID

ENSAMXP00000010393.1

UniProt Accession

W5KS31; W5KS31_ASTMX

Genbank Protein ID

ENSAMXP00000010393

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

APWO01008999

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000010097.1	ENSAMXT00000010393.1	ENSAMXP00000010393.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.00e-16	58.4	1155	1215

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek...slveCekCrewfHpaClkls.....veeelpnsek.wiCpkCrs 53
           ++C vC +++++ +   ++++C  C +w+Hp+C +l+     + + l++++  ++C  C++
   Q: 1155 NFCTVCLKCYQEHEfdsKMMQCASCAHWVHPKCEGLTddlyeILSRLRGKSVvFCCAACSK 1215
           79*******99997778*************************99999999989******75 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MAAAVGGLPA SAVVAGANPW AAARWRFPGR PWSSRSQVKR EKRLRVGRLG AEDAAALSGG 60
PRPVNVGAAL REDPCLLCML GLADKLERQN EAGFCSSDSD EERVFTGFQA DRRWSLRAGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCAG CTGTAGGCGG ATTACCAGCC TCGGCTGTCG TTGCAGGCGC GAACCCGTGG 60
GCCGCGGCGC GCTGGCGTTT CCCGGGCCGG CCATGGTCGT CTCGGAGTCA GGTGAAAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013578	Bos taurus	44.59	0.00e+00	845.00
IUUC-Cja-019138	Callithrix jacchus	44.33	0.00e+00	845.00
IUUC-Cfa-020020	Canis familiaris	44.11	0.00e+00	838.00
IUUC-Csa-024216	Chlorocebus sabaeus	44.71	0.00e+00	841.00
IUUC-Dre-027700	Danio rerio	52.71	0.00e+00	2565.00
IUUC-Eca-034026	Equus caballus	44.40	0.00e+00	773.00
IUUC-Ggo-044791	Gorilla gorilla	45.01	0.00e+00	807.00
IUUC-Hsa-046988	Homo sapiens	43.63	0.00e+00	829.00
IUUC-Mcc-054782	Macaca mulatta	44.02	0.00e+00	832.00
IUUC-Mtr-058327	Medicago truncatula	38.24	5.00e-37	149.00
IUUC-Nle-070085	Nomascus leucogenys	44.24	0.00e+00	825.00
IUUC-Opr-071148	Ochotona princeps	43.33	0.00e+00	837.00
IUUC-Oan-073324	Ornithorhynchus anatinus	41.67	0.00e+00	783.00
IUUC-Olo-080577	Oryza longistaminata	47.06	3.00e-34	140.00
IUUC-Ptr-090902	Pan troglodytes	43.91	0.00e+00	831.00
IUUC-Pan-091930	Papio anubis	44.61	0.00e+00	839.00
IUUC-Pfo-096360	Poecilia formosa	48.41	0.00e+00	1584.00
IUUC-Smo-109164	Selaginella moellendorffii	49.08	1.00e-38	155.00
IUUC-Sly-111158	Solanum lycopersicum	38.32	1.00e-34	142.00
IUUC-Stu-112529	Solanum tuberosum	46.41	5.00e-36	145.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence