iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005102

UUCD1 version

UUC-AnC-00245

Ensembl Protein ID

ENSACAP00000008120.3

UniProt Accession

H9GDQ3; H9GDQ3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008296.3	ENSACAT00000008292.3	ENSACAP00000008120.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-52	172.2	2085	2116
UBD/Beta-Prp	4.40e-81	272.3	1905	2164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtg 33
           H+d+++++ +s+++l+sGs+Dgt+ +WD++t 
   Q: 2085 HQDWISSCTWSGDMLLSGSNDGTVCLWDPKTS 2116
           **********779***************9875 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls..tgkcvhtlkghedsvl 98
           c + s d+++la+g+ ++ + ++++     +     + ++v+ +++   ++ +lv g +D+ ++vw+     ++c   l++he++v+
   Q: 1905 CAAPSLDGNQLAVGYHSDDVWIYRYPWDVSIGPTHCQASGVAICSLAWLDSvFLVGGRNDGSLCVWNTTevLPSCPCPLRAHEKTVT 1991
           4555779999999999999999998888887777777777776666654444**************98877899************* PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqclee...........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.....ktg 169
            l++++    ++s+s+d t+++w  e  +   +           +l+gh++ v+c +++ dg++l++G++Dr++ +Wd+     k  
   Q: 1992 GLAVFK--MLVASTSEDFTVQLWLSEGLKPT-SgttdtsvsplaVLRGHTAGVTCCAFSRDGCYLATGGKDRALFVWDVkdasqKKP 2075
           ******..***************55555555.45999******************************************99999666 PP
   S: 170  kllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
           ++   l   h+d + s +++ ++  l+sgs+dgtv lwd +t++ ++++ gh+++v+ v     +++++s+  Dg +  Wdl+  + 
   Q: 2076 TVCCSLPFCHQDWISSCTWSGDM--LLSGSNDGTVCLWDPKTSQRLQEFLGHQSPVSGVTSE--KDHVISVDRDGLLVAWDLQGVEK 2158
           666666668************75..********************************88777..999***************99888 PP
   S: 257  lktlql 262
           ++ l++
   Q: 2159 TRFLAH 2164
           888776 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MEMTASGPVS SILQDLEESR SRLLCPITPT ASWTITMQTP SSWNKMKPGP AQIAPCAGAK 60
KPLPYSPFSE SNPRWLENPF LKQPISTPLV LQGLEESRAR LLRPIAVSAP KLASVEPSEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAGATGCA CTCACTGACT GTCTTTACCT CCCCATCACA AATAAAAGAG CTGCAGTCCT 60
ATTGCAAGGG GTTAACCAGC CTTTCCTCGT GGACGTGGGA TTGGGAGGGG TTAAATAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0071011--C:precatalytic spliceosome
GO:0005697--C:telomerase holoenzyme complex
GO:0005682--C:U5 snRNP
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0008380--P:RNA splicing
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	42.55	0.00e+00	1606.00
IUUC-Ame-011165	Astyanax mexicanus	35.39	0.00e+00	872.00
IUUC-Bta-012323	Bos taurus	42.66	0.00e+00	1640.00
IUUC-Cja-019005	Callithrix jacchus	42.40	0.00e+00	1701.00
IUUC-Cfa-020803	Canis familiaris	41.65	0.00e+00	1527.00
IUUC-Cpo-022312	Cavia porcellus	41.92	0.00e+00	1583.00
IUUC-Csa-023287	Chlorocebus sabaeus	42.66	0.00e+00	1677.00
IUUC-Dre-028825	Danio rerio	38.16	0.00e+00	1257.00
IUUC-Dno-029455	Dasypus novemcinctus	41.12	0.00e+00	1496.00
IUUC-Dor-030328	Dipodomys ordii	38.97	0.00e+00	1090.00
IUUC-Ete-032385	Echinops telfairi	43.38	0.00e+00	921.00
IUUC-Eca-033726	Equus caballus	43.00	0.00e+00	1680.00
IUUC-Eeu-034665	Erinaceus europaeus	40.06	1.00e-109	392.00
IUUC-Fca-035365	Felis catus	42.49	0.00e+00	1643.00
IUUC-Gmo-039584	Gadus morhua	34.65	2.00e-95	345.00
IUUC-Gac-042307	Gasterosteus aculeatus	37.75	0.00e+00	1092.00
IUUC-Ggo-045432	Gorilla gorilla	40.56	0.00e+00	1541.00
IUUC-Hsa-046182	Homo sapiens	41.75	0.00e+00	1634.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	42.06	0.00e+00	1628.00
IUUC-Lch-050186	Latimeria chalumnae	39.25	5.00e-80	291.00
IUUC-Laf-054524	Loxodonta africana	42.21	0.00e+00	1638.00
IUUC-Mcc-055628	Macaca mulatta	42.76	0.00e+00	1658.00
IUUC-Meu-056338	Macropus eugenii	44.10	0.00e+00	832.00
IUUC-Mmr-060854	Microcebus murinus	42.86	0.00e+00	1670.00
IUUC-Mdo-062247	Monodelphis domestica	42.42	0.00e+00	1623.00
IUUC-Mmu-064406	Mus musculus	41.83	0.00e+00	1553.00
IUUC-Mpu-065806	Mustela putorius furo	43.23	0.00e+00	1657.00
IUUC-Mlu-068116	Myotis lucifugus	42.58	0.00e+00	1564.00
IUUC-Nle-069628	Nomascus leucogenys	43.45	0.00e+00	1553.00
IUUC-Opr-070242	Ochotona princeps	40.52	0.00e+00	1191.00
IUUC-Oan-073598	Ornithorhynchus anatinus	39.58	0.00e+00	1241.00
IUUC-Ocu-073933	Oryctolagus cuniculus	42.34	0.00e+00	1623.00
IUUC-Ola-086886	Oryzias latipes	36.89	0.00e+00	1119.00
IUUC-Oga-088609	Otolemur garnettii	41.99	0.00e+00	1623.00
IUUC-Oar-089957	Ovis aries	42.42	0.00e+00	1578.00
IUUC-Ptr-090577	Pan troglodytes	41.25	0.00e+00	1627.00
IUUC-Pan-092397	Papio anubis	42.38	0.00e+00	1645.00
IUUC-Pma-094373	Petromyzon marinus	33.64	5.00e-34	139.00
IUUC-Pfo-096497	Poecilia formosa	37.45	0.00e+00	1118.00
IUUC-Pab-098028	Pongo abelii	41.69	0.00e+00	1620.00
IUUC-Pca-101002	Procavia capensis	46.55	0.00e+00	959.00
IUUC-Pva-102144	Pteropus vampyrus	41.78	0.00e+00	714.00
IUUC-Rno-105828	Rattus norvegicus	41.85	0.00e+00	1590.00
IUUC-Sha-106469	Sarcophilus harrisii	42.51	0.00e+00	1692.00
IUUC-Sar-113035	Sorex araneus	46.26	0.00e+00	742.00
IUUC-Ssc-116122	Sus scrofa	41.68	0.00e+00	1251.00
IUUC-Tru-118412	Takifugu rubripes	34.70	0.00e+00	1220.00
IUUC-Tsy-119257	Tarsius syrichta	40.88	2.00e-160	561.00
IUUC-Tni-120032	Tetraodon nigroviridis	33.93	3.00e-36	145.00
IUUC-Tbe-127312	Tupaia belangeri	44.06	2.00e-97	352.00
IUUC-Ttr-128335	Tursiops truncatus	40.53	0.00e+00	1581.00
IUUC-Xtr-132524	Xenopus tropicalis	41.82	0.00e+00	1451.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence