iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073933

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02024246

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000002312.2	ENSOCUT00000002319.2	ENSOCUP00000002000.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-49	163.6	2059	2093
UBD/Beta-Prp	4.70e-73	246.0	1885	2113

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtgvl 35
           H d++t++a+  d+ll+s+s Dg++ +WD+ +g +
   Q: 2059 HRDWITGCAWtKDNLLISCSSDGSLGLWDPQSGQQ 2093
           9*********877****************999876 PP

UBD/Beta-Prp

   S: 57   avkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvnc 142
           +v +sp g+  + g + + i+++ + +g++    ++ +  v +l++    ++lvsG +d  ++ w l++ +  +  +ls h++ v +
   Q: 1885 SVALSPGGDRVAVGYRADGIRIYKIPSGSQGAQCQALDVAVSALAWLS-PEVLVSGAEDGSLQGWLLRESTLQSLwLLSRHQKPVLG 1970
           677889999999999999999999999999999999999999999987.79999999999999997777665544799999999999 PP
   S: 143  vvvhpdgnllvsGslDrtvrlWdlktgkllrtl.........tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec...vrt 217
           +++++   ll+++s D tvrlW+ +  +l ++          +g h+++v++  f+ +g +l++g++d+t+  wd++t ++   + t
   Q: 1971 LATSQ--ELLAAASEDFTVRLWQRQLLTLPHKSedfpqgtelRG-HEGPVTCCGFSADGGSLATGGRDQTLLCWDVRTPQTpvlICT 2054
           99998..9999999999999999955555555555566666576.999999999999999999999999999999995555555888 PP
   S: 218  lng.htdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvl 280
           + + h+d+++  + + +d++l+s+ssDgs+ +Wd +sg+ l+ + +h+s v+svav+    +  
   Q: 2055 FPAcHRDWITGCAWT-KDNLLISCSSDGSLGLWDPQSGQQLGRFLGHQSAVSSVAVV----KST 2113
           876699999999888.99999999999999999999999999999999999999993....333 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MERLHGHMSA NPDILSLENR CLATLPDLKT MEKPHGHMSA YRDILSLENR CLATISNVKS 60
TVSGSPLLQC LQIPHMMQAD LCSLNTRNCL VSEPPTWKSR CLSEGLDPRT CPKALKTIST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAGAC TCCATGGGCA CATGTCTGCC AACCCAGACA TCCTCTCCTT GGAGAACAGG 60
TGTCTGGCCA CACTTCCTGA CCTGAAGACC ATGGAGAAAC CACACGGGCA TATGTCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	76.50	0.00e+00	3691.00
IUUC-Aca-005102	Anolis carolinensis	42.52	0.00e+00	1645.00
IUUC-Ame-011165	Astyanax mexicanus	33.02	0.00e+00	815.00
IUUC-Bta-012323	Bos taurus	77.38	0.00e+00	3763.00
IUUC-Cja-019005	Callithrix jacchus	79.64	0.00e+00	3999.00
IUUC-Cfa-020803	Canis familiaris	70.79	0.00e+00	3341.00
IUUC-Cpo-022312	Cavia porcellus	72.89	0.00e+00	3431.00
IUUC-Csa-023287	Chlorocebus sabaeus	80.54	0.00e+00	3975.00
IUUC-Cin-025646	Ciona intestinalis	23.72	2.00e-15	78.20
IUUC-Dre-028825	Danio rerio	35.56	0.00e+00	1165.00
IUUC-Dno-029455	Dasypus novemcinctus	76.55	0.00e+00	3637.00
IUUC-Dor-030328	Dipodomys ordii	71.44	0.00e+00	2492.00
IUUC-Ete-032385	Echinops telfairi	72.85	0.00e+00	1948.00
IUUC-Eca-033726	Equus caballus	80.68	0.00e+00	3995.00
IUUC-Eeu-034665	Erinaceus europaeus	64.50	0.00e+00	919.00
IUUC-Fca-035365	Felis catus	77.72	0.00e+00	3783.00
IUUC-Gmo-039584	Gadus morhua	32.00	4.00e-125	443.00
IUUC-Gac-042307	Gasterosteus aculeatus	36.23	0.00e+00	1031.00
IUUC-Ggo-045432	Gorilla gorilla	77.89	0.00e+00	3825.00
IUUC-Hsa-046182	Homo sapiens	80.26	0.00e+00	3994.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	78.54	0.00e+00	3850.00
IUUC-Lch-050186	Latimeria chalumnae	39.28	2.00e-83	302.00
IUUC-Laf-054524	Loxodonta africana	76.75	0.00e+00	3830.00
IUUC-Mcc-055628	Macaca mulatta	80.61	0.00e+00	4000.00
IUUC-Meu-056338	Macropus eugenii	63.95	0.00e+00	1310.00
IUUC-Mmr-060854	Microcebus murinus	79.59	0.00e+00	3925.00
IUUC-Mdo-062247	Monodelphis domestica	60.85	0.00e+00	2824.00
IUUC-Mmu-064406	Mus musculus	71.89	0.00e+00	3492.00
IUUC-Mpu-065806	Mustela putorius furo	76.32	0.00e+00	3754.00
IUUC-Mlu-068116	Myotis lucifugus	79.05	0.00e+00	3776.00
IUUC-Nle-069628	Nomascus leucogenys	80.59	0.00e+00	3573.00
IUUC-Opr-070242	Ochotona princeps	82.03	0.00e+00	2980.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.74	0.00e+00	1953.00
IUUC-Ola-086886	Oryzias latipes	34.31	0.00e+00	1107.00
IUUC-Oga-088609	Otolemur garnettii	76.85	0.00e+00	3767.00
IUUC-Oar-089957	Ovis aries	76.90	0.00e+00	3662.00
IUUC-Ptr-090577	Pan troglodytes	78.90	0.00e+00	3921.00
IUUC-Pan-092397	Papio anubis	80.15	0.00e+00	3971.00
IUUC-Pma-094373	Petromyzon marinus	33.59	6.00e-68	251.00
IUUC-Pfo-096497	Poecilia formosa	36.59	0.00e+00	1090.00
IUUC-Pab-098028	Pongo abelii	80.09	0.00e+00	3941.00
IUUC-Pca-101002	Procavia capensis	82.22	0.00e+00	1873.00
IUUC-Pva-102144	Pteropus vampyrus	71.46	0.00e+00	1585.00
IUUC-Rno-105828	Rattus norvegicus	71.60	0.00e+00	3523.00
IUUC-Sha-106469	Sarcophilus harrisii	60.44	0.00e+00	2847.00
IUUC-Sar-113035	Sorex araneus	78.01	0.00e+00	1457.00
IUUC-Ssc-116122	Sus scrofa	79.90	0.00e+00	2885.00
IUUC-Tru-118412	Takifugu rubripes	33.51	0.00e+00	1191.00
IUUC-Tsy-119257	Tarsius syrichta	72.93	0.00e+00	1519.00
IUUC-Tni-120032	Tetraodon nigroviridis	34.21	3.00e-44	171.00
IUUC-Tbe-127312	Tupaia belangeri	64.74	0.00e+00	965.00
IUUC-Ttr-128335	Tursiops truncatus	75.34	0.00e+00	3698.00
IUUC-Xtr-132524	Xenopus tropicalis	39.68	0.00e+00	1381.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence