iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004204

Ensembl Protein ID

ENSAPLP00000002025.1

UniProt Accession

U3I454; U3I454_ANAPL

Genbank Protein ID

ENSAPLP00000002025

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01093199

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000002578.1	ENSAPLT00000002606.1	ENSAPLP00000002025.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-84	283.0	26	736

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg...........ellkslqklfeel.......w.... 61
           +Gl+NlgNtCY+NS+LQ+L+++p ++  +++      kkke+l+ee +++ ++           el++sl++l+ ++       +    
   Q: 26   VGLNNLGNTCYLNSILQVLYFCPGFKTGVKHlyniisKKKESLKEEGEQKADKgnckedplasyELICSLHSLILSIeqlqasfLlnpe 114
           6******************************8888887777777776555444889999999998888888888888554444425555 PP
   S: 62   .kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk....eknkpkeeeeeedkselsde................ 129
            ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++     e nk   ee  ++ +e   +                
   Q: 115  kYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkkeELNKLPLEEPAAKLEE---Kldenvesngignsaee 200
           588888*****************************************5544443333333333333222...13336777788999999 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 201  edsepsgpvgevaedkllkgngkrksdaeggnakkkskvskeqiaaeenqrqtrskrkatgeklenqtdaiakcstesesakptqkksr 289
           99*************************************************************************************** PP
   S: 130  ...............................................................................aeekkkkknk 139
                                                                                          ++e      +
   Q: 290  lrlnwlkssckqpsilskfyslgklttnlgskdpakeyddceleessvksengnnikeeghepafaveshnekgtekepKKEG-----T 373
           ********************************************************************998877544333333.....1 PP
   S: 140  .....slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyyce 209
                +l+++lFqgql  +++clec+  ++r+e+f+d+s+pv+++e +k+e              +l++++++f++ e++ ge+ky+ce
   Q: 374  elavfELVEKLFQGQLVLRTRCLECECFTERREDFQDISVPVQEDELSKTEesseispepktemkTLKWAISQFASVERIVGEDKYFCE 462
           46666*****************************************998889************************************* PP
   S: 210  kckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slss 292
           +c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ss
   Q: 463  NCHHYTEAERSLLFDKMPEVITIHLKCFaasgiEFDCYGGL-SKINTPLLTPLKLSLEEWSTKPT-----NDTYGLFAVVMHSGiTISS 545
           *************************************9555.6********************98.....789**************** PP
   S: 293  GHYvayvkn................................................................................ 301
           GHY+a vk                                                                                 
   Q: 546  GHYTASVKItdlnsleidkgnfitdqmyemikpeplneeeartvaedyddgevsfrvngnaqpgkvlnkknmeavgllggqksksdcdl 634
           ***************************************************************************************** PP
   S: 302  ............................................................ekgkWllfdDskVtevkeeevleetg... 327
                                                                        +gkWllfdDs+V++++e+++l++ +   
   Q: 635  ynnkpanaekflnivtenrnpessntngsvecstehsdqngvafsglenkalyvlqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpts 723
           ************************9999999999999999999999988888888877766999*******************888*** PP
   S: 328  ...staYvlfYkr 337
              st+Y+lfYk+
   Q: 724  sstSTPYLLFYKK 736
           ***********97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

SDQVVPAAQP PSLVSCERKD NMLPFVGLNN LGNTCYLNSI LQVLYFCPGF KTGVKHLYNI 60
ISKKKESLKE EGEQKADKGN CKEDPLASYE LICSLHSLIL SIEQLQASFL LNPEKYTDEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGACCAGG TTGTTCCTGC AGCACAGCCT CCCTCACTTG TCAGCTGCGA GAGGAAAGAC 60
AACATGTTGC CTTTCGTGGG CCTGAATAAT CTCGGTAACA CTTGTTACCT GAACAGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	74.26	0.00e+00	1009.00
IUUC-Aca-004637	Anolis carolinensis	73.04	0.00e+00	967.00
IUUC-Ame-011718	Astyanax mexicanus	50.00	3.00e-165	575.00
IUUC-Bta-012552	Bos taurus	71.91	0.00e+00	992.00
IUUC-Cja-019588	Callithrix jacchus	73.14	0.00e+00	1006.00
IUUC-Cfa-020211	Canis familiaris	74.63	0.00e+00	1023.00
IUUC-Cpo-021551	Cavia porcellus	67.97	0.00e+00	937.00
IUUC-Csa-024186	Chlorocebus sabaeus	74.36	0.00e+00	1018.00
IUUC-Cho-024739	Choloepus hoffmanni	65.09	8.00e-129	454.00
IUUC-Dre-028184	Danio rerio	48.89	5.00e-174	604.00
IUUC-Dno-029669	Dasypus novemcinctus	72.14	0.00e+00	1000.00
IUUC-Dor-030168	Dipodomys ordii	68.73	0.00e+00	878.00
IUUC-Dme-031732	Drosophila melanogaster	29.38	1.00e-18	88.60
IUUC-Ete-032825	Echinops telfairi	69.08	0.00e+00	713.00
IUUC-Eca-033595	Equus caballus	73.01	0.00e+00	1001.00
IUUC-Eeu-034877	Erinaceus europaeus	70.62	2.00e-121	429.00
IUUC-Fca-035381	Felis catus	72.38	0.00e+00	669.00
IUUC-Fal-037592	Ficedula albicollis	84.80	0.00e+00	1141.00
IUUC-Gmo-039680	Gadus morhua	46.40	3.00e-157	548.00
IUUC-Gga-041196	Gallus gallus	92.02	0.00e+00	1255.00
IUUC-Gac-042292	Gasterosteus aculeatus	47.05	1.00e-134	473.00
IUUC-Ggo-044671	Gorilla gorilla	73.82	0.00e+00	1008.00
IUUC-Hsa-047020	Homo sapiens	73.82	0.00e+00	1012.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	67.03	0.00e+00	863.00
IUUC-Lch-050543	Latimeria chalumnae	60.19	0.00e+00	739.00
IUUC-Loc-052338	Lepisosteus oculatus	53.16	0.00e+00	682.00
IUUC-Laf-053707	Loxodonta africana	72.58	0.00e+00	995.00
IUUC-Mcc-055885	Macaca mulatta	74.09	0.00e+00	1018.00
IUUC-Meu-056573	Macropus eugenii	68.95	0.00e+00	876.00
IUUC-Mga-059346	Meleagris gallopavo	93.08	0.00e+00	1311.00
IUUC-Mmr-061612	Microcebus murinus	72.97	0.00e+00	983.00
IUUC-Mdo-062887	Monodelphis domestica	71.12	0.00e+00	951.00
IUUC-Mmu-064044	Mus musculus	72.20	0.00e+00	990.00
IUUC-Mpu-066847	Mustela putorius furo	74.36	0.00e+00	1021.00
IUUC-Mlu-067684	Myotis lucifugus	74.26	0.00e+00	1011.00
IUUC-Nle-070057	Nomascus leucogenys	73.95	0.00e+00	1013.00
IUUC-Opr-070463	Ochotona princeps	66.67	0.00e+00	857.00
IUUC-Ont-071975	Oreochromis niloticus	45.60	3.00e-154	538.00
IUUC-Ocu-074840	Oryctolagus cuniculus	72.20	0.00e+00	990.00
IUUC-Ola-087088	Oryzias latipes	47.25	2.00e-162	565.00
IUUC-Oga-088472	Otolemur garnettii	72.43	0.00e+00	977.00
IUUC-Oar-089498	Ovis aries	72.20	0.00e+00	995.00
IUUC-Ptr-091395	Pan troglodytes	73.82	0.00e+00	1011.00
IUUC-Pan-092462	Papio anubis	74.22	0.00e+00	1019.00
IUUC-Psi-093583	Pelodiscus sinensis	83.18	0.00e+00	1071.00
IUUC-Pma-094644	Petromyzon marinus	46.00	1.00e-25	109.00
IUUC-Pfo-096314	Poecilia formosa	46.98	4.00e-153	535.00
IUUC-Pab-098568	Pongo abelii	73.82	0.00e+00	1011.00
IUUC-Pca-100948	Procavia capensis	79.42	4.00e-132	465.00
IUUC-Pva-102853	Pteropus vampyrus	73.76	0.00e+00	1005.00
IUUC-Rno-105573	Rattus norvegicus	73.41	0.00e+00	999.00
IUUC-Sha-107495	Sarcophilus harrisii	68.42	0.00e+00	844.00
IUUC-Sar-113545	Sorex araneus	62.05	0.00e+00	781.00
IUUC-Ssc-115962	Sus scrofa	73.18	0.00e+00	995.00
IUUC-Tgu-116731	Taeniopygia guttata	84.78	0.00e+00	1143.00
IUUC-Tru-117893	Takifugu rubripes	46.57	5.00e-141	494.00
IUUC-Tsy-119644	Tarsius syrichta	80.13	3.00e-135	475.00
IUUC-Tni-119819	Tetraodon nigroviridis	45.79	4.00e-156	544.00
IUUC-Tbe-127272	Tupaia belangeri	69.22	0.00e+00	917.00
IUUC-Ttr-128404	Tursiops truncatus	73.28	0.00e+00	995.00
IUUC-Vpa-130205	Vicugna pacos	72.07	0.00e+00	994.00
IUUC-Xtr-132613	Xenopus tropicalis	56.30	0.00e+00	731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence