iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005169

Ensembl Protein ID

ENSACAP00000003852.3

UniProt Accession

H9G8A7; H9G8A7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

ARHGEF15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003870.3	ENSACAT00000003944.3	ENSACAP00000003852.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.10e-11	42.6	584	634

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 11   dyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            y+a++ deL+l+  d+v v+   +++egW +gv+ + gk+G fP+ +v+++ 
   Q: 584  AYTATQADELSLEPTDIVNVL--RKTNEGWYEGVRLADGKKGWFPSRYVQEIT 634
           7********************..99************************9985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

PAVSCGGEQN GVELPPSCSS GCPCICHQHR PGMVLAWVPA PTLPAETRHS PRSKKPLDLP 60
PSANGHPEGG VVLTSYRSTA EPLPPRCPPL MPKPPRRSKG GSAVSFDGDP PPPLPQGLPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGCTGTTT CCTGTGGAGG GGAGCAGAAC GGTGTAGAAT TGCCTCCTTC CTGCTCCTCT 60
GGCTGCCCCT GCATCTGCCA CCAACACCGG CCCGGCATGG TTTTGGCCTG GGTCCCGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011993--PH_dom-like
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50002--SH3

Pfam

PF00621--RhoGEF
PF00018--SH3_1

SMART

SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0030425--C:dendrite
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:2000297--P:negative regulation of synapse maturation
GO:0035023--P:regulation of Rho protein signal transduction
GO:0061299--P:retina vasculature morphogenesis in camera-type eye

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013108	Bos taurus	45.43	9.00e-98	350.00
IUUC-Cin-025559	Ciona intestinalis	39.83	6.00e-22	96.30
IUUC-Eca-033839	Equus caballus	45.01	3.00e-98	352.00
IUUC-Lch-049409	Latimeria chalumnae	64.88	3.00e-170	591.00
IUUC-Mac-065506	Musa acuminata	23.23	1.90e-01	31.60
IUUC-Mlu-067642	Myotis lucifugus	45.12	3.00e-98	352.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence