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Tag Content
iUUCD ID IUUC-Ssc-116193
Ensembl Protein ID ENSSSCP00000014933.2
UniProt Accession F1S3C1; F1S3C1_PIG
Genbank Protein ID ENSSSCP00000014933
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID CU915382
Gene Name NSD1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000014044.2 ENSSSCT00000015341.2 ENSSSCP00000014933.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.30e-14 54.4 1406 1446
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC egg+    l++C+ C  +fH +Cl++      p+ + w+C++C+
   Q: 1406 WCFVCSEGGS----LLCCDSCPAAFHRECLNID----IPEGN-WYCNDCK 1446
           8*********....*******************....99996.******8 PP
   
Organism Sus scrofa
Protein Sequence
(Fasta)
CQPKKKATPL KYEVGDLIWA KFKRRPWWPC RICSDPLINT HSKMKVSNRR PYRQYYVEAF 60
GDPSERAWVA GKAIVMFEGR HQFEELPVLR RRGKQKEKGY RHKVPQKILS KWEASVGLAE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-116193|E3,PHD|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTAATTTTT ATTGATGCCC ATGTTTTGTC TGTCTAAAGT GTCAACCCAA GAAAAAGGCT 60
ACGCCATTGA AGTATGAAGT TGGAGATCTC ATCTGGGCAA AATTCAAGAG ACGTCCATGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-116193|E3,PHD|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0046975--F:histone methyltransferase activity (H3-K36 specific)
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0008270--F:zinc ion binding
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0000414--P:regulation of histone H3-K36 methylation
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:1903025--P:regulation of RNA polymerase II regulatory region sequence-specific DNA binding
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001795 Ailuropoda melanoleuca 93.19 0.00e+00 4293.00
IUUC-Apl-003953 Anas platyrhynchos 57.56 0.00e+00 2245.00
IUUC-Aca-005339 Anolis carolinensis 58.87 0.00e+00 1496.00
IUUC-Bta-012966 Bos taurus 93.61 0.00e+00 4378.00
IUUC-Bdi-014781 Brachypodium distachyon 30.58 1.00e-13 72.00
IUUC-Bol-016001 Brassica oleracea 29.51 2.00e-16 81.30
IUUC-Bra-017864 Brassica rapa 28.96 4.00e-15 77.80
IUUC-Cja-018780 Callithrix jacchus 89.47 0.00e+00 3861.00
IUUC-Cfa-020975 Canis familiaris 92.44 0.00e+00 4254.00
IUUC-Cpo-021331 Cavia porcellus 87.56 0.00e+00 2667.00
IUUC-Csa-024226 Chlorocebus sabaeus 90.44 0.00e+00 4138.00
IUUC-Cho-024464 Choloepus hoffmanni 75.08 0.00e+00 1363.00
IUUC-Csv-026298 Ciona savignyi 38.54 6.00e-57 214.00
IUUC-Dre-028152 Danio rerio 62.73 0.00e+00 1249.00
IUUC-Dno-029230 Dasypus novemcinctus 87.21 0.00e+00 3968.00
IUUC-Dor-031016 Dipodomys ordii 81.76 0.00e+00 1320.00
IUUC-Dme-032193 Drosophila melanogaster 36.09 2.00e-122 434.00
IUUC-Eca-033591 Equus caballus 92.44 0.00e+00 4301.00
IUUC-Fca-035791 Felis catus 93.11 0.00e+00 4405.00
IUUC-Fal-037378 Ficedula albicollis 57.77 0.00e+00 2051.00
IUUC-Gmo-038919 Gadus morhua 71.36 0.00e+00 936.00
IUUC-Gga-040881 Gallus gallus 58.02 0.00e+00 2154.00
IUUC-Gac-041378 Gasterosteus aculeatus 77.71 0.00e+00 1068.00
IUUC-Hsa-046436 Homo sapiens 90.94 0.00e+00 4172.00
IUUC-Hvu-047760 Hordeum vulgare 40.98 2.00e-09 58.90
IUUC-Itr-048194 Ictidomys tridecemlineatus 88.54 0.00e+00 4155.00
IUUC-Lch-049684 Latimeria chalumnae 50.98 0.00e+00 1588.00
IUUC-Laf-054046 Loxodonta africana 89.76 0.00e+00 4108.00
IUUC-Mcc-055593 Macaca mulatta 90.32 0.00e+00 4140.00
IUUC-Mga-059756 Meleagris gallopavo 57.11 0.00e+00 2222.00
IUUC-Mmr-061182 Microcebus murinus 88.81 0.00e+00 4127.00
IUUC-Mdo-061984 Monodelphis domestica 68.59 0.00e+00 2982.00
IUUC-Mmu-063605 Mus musculus 82.15 0.00e+00 3779.00
IUUC-Mpu-066446 Mustela putorius furo 92.65 0.00e+00 4354.00
IUUC-Mlu-067261 Myotis lucifugus 90.48 0.00e+00 4183.00
IUUC-Nle-069818 Nomascus leucogenys 90.65 0.00e+00 4160.00
IUUC-Opr-070842 Ochotona princeps 83.81 0.00e+00 2320.00
IUUC-Ont-072448 Oreochromis niloticus 75.82 0.00e+00 1149.00
IUUC-Oan-073496 Ornithorhynchus anatinus 76.01 0.00e+00 1628.00
IUUC-Ocu-074918 Oryctolagus cuniculus 89.44 0.00e+00 4226.00
IUUC-Obr-076753 Oryza brachyantha 54.84 9.00e-08 53.10
IUUC-Ogu-078898 Oryza glumaepatula 29.48 3.00e-10 59.30
IUUC-Ola-087518 Oryzias latipes 76.86 0.00e+00 1056.00
IUUC-Oga-088743 Otolemur garnettii 87.73 0.00e+00 3999.00
IUUC-Oar-090265 Ovis aries 93.19 0.00e+00 4355.00
IUUC-Ptr-090521 Pan troglodytes 90.94 0.00e+00 4178.00
IUUC-Psi-093245 Pelodiscus sinensis 59.50 0.00e+00 2023.00
IUUC-Ppa-095277 Physcomitrella patens 28.98 5.00e-11 62.40
IUUC-Pfo-096066 Poecilia formosa 76.03 0.00e+00 1204.00
IUUC-Pab-098644 Pongo abelii 90.44 0.00e+00 4117.00
IUUC-Pva-103094 Pteropus vampyrus 88.88 0.00e+00 2167.00
IUUC-Rno-105803 Rattus norvegicus 82.36 0.00e+00 3765.00
IUUC-Sha-107278 Sarcophilus harrisii 69.25 0.00e+00 3033.00
IUUC-Sar-113402 Sorex araneus 78.73 0.00e+00 2550.00
IUUC-Sbi-114400 Sorghum bicolor 36.54 4.00e-13 66.20
IUUC-Tgu-116532 Taeniopygia guttata 90.00 0.00e+00 1252.00
IUUC-Tru-117988 Takifugu rubripes 77.71 0.00e+00 1199.00
IUUC-Tsy-118830 Tarsius syrichta 88.96 0.00e+00 3605.00
IUUC-Xma-133606 Xiphophorus maculatus 76.95 0.00e+00 1140.00
Created Date 25-Jun-2017

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