iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-060087

Ensembl Protein ID

ENSMGAP00000014526.2

UniProt Accession

G1NLV8; G1NLV8_MELGA

Protein Name

Uncharacterized protein

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000013743.2	ENSMGAT00000015462.2	ENSMGAP00000014526.2
ENSMGAG00000013743.2	ENSMGAT00000018522.1	ENSMGAP00000017770.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.00e-17	60.5	429	485

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q++deL++k+Gd ++ + ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 429  RVRALYDYEGQEQDELSFKAGDELTKM-ENEDEQGWCKG-RLDNGQVGLYPANYVEPIQ 485
           799***********************9.9999*******.59*************9985 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MSGSYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCND LMNCIHERAR IEKVYAQQLT 60
EWAKRWKQLV EKGPQYGTVE RAWCAFMSEA EKVSELHLEV KGSLMNEDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAACAGTC CATATAGAAA TCAGTCTGAA AATCTGGAGA GAGAATTTGG GGAATGGTTG 60
TGTCGTTCCA ACGGCTACTG ACTTGACTAA TATACAGTAA GTGTGTGAAT AAAGTATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	83.37	0.00e+00	744.00
IUUC-Apl-003574	Anas platyrhynchos	91.75	0.00e+00	794.00
IUUC-Aca-004251	Anolis carolinensis	82.16	0.00e+00	714.00
IUUC-Ame-011756	Astyanax mexicanus	63.69	0.00e+00	626.00
IUUC-Bta-013193	Bos taurus	80.90	0.00e+00	694.00
IUUC-Cja-018756	Callithrix jacchus	83.37	0.00e+00	733.00
IUUC-Cfa-020545	Canis familiaris	83.78	0.00e+00	775.00
IUUC-Cpo-022000	Cavia porcellus	78.85	0.00e+00	783.00
IUUC-Csa-024030	Chlorocebus sabaeus	80.72	0.00e+00	642.00
IUUC-Dre-028104	Danio rerio	59.04	1.00e-151	528.00
IUUC-Dno-029429	Dasypus novemcinctus	80.44	0.00e+00	692.00
IUUC-Dor-030122	Dipodomys ordii	76.34	0.00e+00	663.00
IUUC-Eca-033367	Equus caballus	81.65	0.00e+00	723.00
IUUC-Eeu-034821	Erinaceus europaeus	72.48	0.00e+00	642.00
IUUC-Fca-036079	Felis catus	82.94	0.00e+00	737.00
IUUC-Fal-036682	Ficedula albicollis	92.09	0.00e+00	793.00
IUUC-Gga-040717	Gallus gallus	92.95	0.00e+00	800.00
IUUC-Gac-042262	Gasterosteus aculeatus	61.68	9.00e-159	552.00
IUUC-Gma-044347	Glycine max	28.21	2.40e-01	29.30
IUUC-Ggo-044841	Gorilla gorilla	82.75	0.00e+00	702.00
IUUC-Hsa-046411	Homo sapiens	82.34	0.00e+00	698.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	82.55	0.00e+00	705.00
IUUC-Loc-051975	Lepisosteus oculatus	67.02	0.00e+00	634.00
IUUC-Laf-053839	Loxodonta africana	78.96	0.00e+00	727.00
IUUC-Mcc-055783	Macaca mulatta	82.14	0.00e+00	698.00
IUUC-Mvi-060548	Microbotryum violaceum	41.51	2.00e-07	51.60
IUUC-Mmr-060827	Microcebus murinus	83.78	0.00e+00	741.00
IUUC-Mmu-064109	Mus musculus	82.55	0.00e+00	732.00
IUUC-Mpu-066591	Mustela putorius furo	83.78	0.00e+00	746.00
IUUC-Mlu-067826	Myotis lucifugus	83.16	0.00e+00	739.00
IUUC-Nle-069797	Nomascus leucogenys	82.55	0.00e+00	700.00
IUUC-Oan-073076	Ornithorhynchus anatinus	75.58	2.00e-135	474.00
IUUC-Ocu-074425	Oryctolagus cuniculus	82.47	0.00e+00	706.00
IUUC-Ola-087556	Oryzias latipes	62.43	5.00e-151	526.00
IUUC-Oga-089009	Otolemur garnettii	76.85	0.00e+00	681.00
IUUC-Oar-089806	Ovis aries	81.31	0.00e+00	697.00
IUUC-Ptr-091111	Pan troglodytes	82.34	0.00e+00	696.00
IUUC-Pan-091749	Papio anubis	79.55	0.00e+00	687.00
IUUC-Psi-093704	Pelodiscus sinensis	85.04	0.00e+00	757.00
IUUC-Pfo-096680	Poecilia formosa	61.09	1.00e-156	545.00
IUUC-Pva-102649	Pteropus vampyrus	82.75	0.00e+00	709.00
IUUC-Ptt-103815	Puccinia triticina	43.64	4.00e-10	58.20
IUUC-Rno-105431	Rattus norvegicus	81.80	0.00e+00	758.00
IUUC-Sha-106641	Sarcophilus harrisii	84.58	0.00e+00	743.00
IUUC-Sar-113461	Sorex araneus	72.48	8.00e-180	622.00
IUUC-Ssc-115349	Sus scrofa	82.72	0.00e+00	704.00
IUUC-Tgu-116876	Taeniopygia guttata	92.74	0.00e+00	797.00
IUUC-Tru-118306	Takifugu rubripes	63.97	8.00e-164	569.00
IUUC-Tsy-118901	Tarsius syrichta	72.02	2.00e-123	435.00
IUUC-Tni-120120	Tetraodon nigroviridis	65.03	2.00e-168	584.00
IUUC-Xtr-132925	Xenopus tropicalis	77.00	0.00e+00	700.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence