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Tag Content
iUUCD ID IUUC-Apl-003193
Ensembl Protein ID ENSAPLP00000010914.1
UniProt Accession U3IUJ1; U3IUJ1_ANAPL
Genbank Protein ID ENSAPLP00000010914
Protein Name Uncharacterized protein
Genbank Nucleotide ID ADON01119486
Gene Name MDM2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAPLG00000011164.1 ENSAPLT00000011633.1 ENSAPLP00000010914.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 65.59 7.00e-158 555.00 IUUC-Hsa-046376
E3 activity/RING/RING 59.44 2.00e-131 466.00 IUUC-Mmu-063207
E3 activity/RING/RING 61.18 3.00e-138 488.00 IUUC-Rno-105641
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Anas platyrhynchos
Protein Sequence
(Fasta)
SLRCRQMCNT KMSALTDGAA VTASEQEALV KPKPLLLKLL KLAGAEKDTF TMKEVIFYLG 60
QYIMSKQLYD EKEQHIVHCA NDLLGDLFGV TSFSVKEHRR VYSMICRNLV AINQQDCTLA 120
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Protein Fasta Sequence



>IUUC-Apl-003193|E3,RING|Anas platyrhynchos
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Nucleotide Sequence
(Fasta)
TCCCTTCGCT GCAGGCAGAT GTGCAACACC AAGATGTCCG CCCTCACGGA TGGCGCCGCT 60
GTCACCGCCT CGGAGCAGGA GGCCCTGGTC AGTACCCGGG GGGGCTGGGG CTTTCTGTCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Apl-003193|E3,RING|Anas platyrhynchos
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005730--C:nucleolus
GO:0043234--C:protein complex
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0003283--P:atrial septum development
GO:0003181--P:atrioventricular valve morphogenesis
GO:0001568--P:blood vessel development
GO:0001974--P:blood vessel remodeling
GO:0060411--P:cardiac septum morphogenesis
GO:0071456--P:cellular response to hypoxia
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0003203--P:endocardial cushion morphogenesis
GO:0045184--P:establishment of protein localization
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0018205--P:peptidyl-lysine modification
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0006461--P:protein complex assembly
GO:0031648--P:protein destabilization
GO:0034504--P:protein localization to nucleus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0002027--P:regulation of heart rate
GO:0046677--P:response to antibiotic
GO:0007089--P:traversing start control point of mitotic cell cycle
GO:0003281--P:ventricular septum development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002039 Ailuropoda melanoleuca 66.73 2.00e-166 578.00
IUUC-Aca-004305 Anolis carolinensis 62.64 2.00e-124 439.00
IUUC-Ame-010675 Astyanax mexicanus 45.73 8.00e-86 310.00
IUUC-Bta-013270 Bos taurus 65.78 6.00e-158 550.00
IUUC-Cja-019744 Callithrix jacchus 66.40 8.00e-165 572.00
IUUC-Cfa-020807 Canis familiaris 64.98 2.00e-144 505.00
IUUC-Cpo-022182 Cavia porcellus 64.91 1.00e-148 519.00
IUUC-Cre-022828 Chlamydomonas reinhardtii 38.00 3.00e-06 42.40
IUUC-Csa-023541 Chlorocebus sabaeus 66.67 2.00e-161 561.00
IUUC-Cho-024831 Choloepus hoffmanni 55.56 3.00e-59 221.00
IUUC-Cin-025448 Ciona intestinalis 28.25 5.00e-21 94.00
IUUC-Dre-028419 Danio rerio 44.24 6.00e-79 287.00
IUUC-Dno-028950 Dasypus novemcinctus 65.92 2.00e-161 561.00
IUUC-Dor-031048 Dipodomys ordii 52.61 4.00e-119 421.00
IUUC-Ete-032264 Echinops telfairi 52.32 5.00e-125 440.00
IUUC-Eca-033301 Equus caballus 60.98 1.00e-151 529.00
IUUC-Eeu-035005 Erinaceus europaeus 61.55 5.00e-130 457.00
IUUC-Fca-035454 Felis catus 65.85 8.00e-155 540.00
IUUC-Fal-036720 Ficedula albicollis 90.20 5.00e-108 383.00
IUUC-Gmo-039296 Gadus morhua 40.40 5.00e-45 174.00
IUUC-Gga-040251 Gallus gallus 90.70 0.00e+00 770.00
IUUC-Gac-041528 Gasterosteus aculeatus 41.06 5.00e-39 155.00
IUUC-Ggo-044948 Gorilla gorilla 62.32 1.00e-150 525.00
IUUC-Hsa-046376 Homo sapiens 66.80 7.00e-165 573.00
IUUC-Itr-048328 Ictidomys tridecemlineatus 65.52 3.00e-155 541.00
IUUC-Lch-050037 Latimeria chalumnae 58.49 2.00e-118 419.00
IUUC-Loc-051837 Lepisosteus oculatus 50.70 5.00e-118 417.00
IUUC-Laf-053483 Loxodonta africana 63.77 9.00e-158 549.00
IUUC-Mcc-055294 Macaca mulatta 66.60 7.00e-164 570.00
IUUC-Mga-060007 Meleagris gallopavo 84.58 0.00e+00 659.00
IUUC-Mmr-060673 Microcebus murinus 65.71 3.00e-163 567.00
IUUC-Mdo-063057 Monodelphis domestica 69.53 2.00e-171 594.00
IUUC-Mmu-063207 Mus musculus 61.45 4.00e-128 451.00
IUUC-Mpu-065836 Mustela putorius furo 66.80 1.00e-164 572.00
IUUC-Mlu-068193 Myotis lucifugus 64.19 2.00e-148 518.00
IUUC-Nle-069927 Nomascus leucogenys 66.40 1.00e-163 568.00
IUUC-Opr-070590 Ochotona princeps 63.05 1.00e-144 505.00
IUUC-Ont-071984 Oreochromis niloticus 43.38 9.00e-81 293.00
IUUC-Oan-072744 Ornithorhynchus anatinus 71.14 1.00e-156 545.00
IUUC-Ocu-074071 Oryctolagus cuniculus 64.52 4.00e-155 541.00
IUUC-Ola-087329 Oryzias latipes 40.20 8.00e-77 280.00
IUUC-Oga-088135 Otolemur garnettii 61.21 9.00e-150 523.00
IUUC-Oar-089726 Ovis aries 65.38 9.00e-164 569.00
IUUC-Ptr-091399 Pan troglodytes 66.40 6.00e-164 570.00
IUUC-Pan-092720 Papio anubis 66.60 7.00e-164 570.00
IUUC-Psi-093591 Pelodiscus sinensis 71.65 7.00e-152 530.00
IUUC-Pma-094500 Petromyzon marinus 35.35 9.00e-28 115.00
IUUC-Pfo-096316 Poecilia formosa 42.33 3.00e-78 285.00
IUUC-Pab-097696 Pongo abelii 66.60 1.00e-162 565.00
IUUC-Pca-100974 Procavia capensis 61.90 4.00e-163 567.00
IUUC-Pva-102488 Pteropus vampyrus 63.86 4.00e-143 501.00
IUUC-Rno-105641 Rattus norvegicus 63.01 4.00e-135 474.00
IUUC-Sha-107314 Sarcophilus harrisii 70.33 3.00e-178 617.00
IUUC-Sar-112938 Sorex araneus 62.60 6.00e-156 543.00
IUUC-Ssc-115495 Sus scrofa 65.65 2.00e-155 542.00
IUUC-Tgu-116623 Taeniopygia guttata 88.14 0.00e+00 688.00
IUUC-Tru-117820 Takifugu rubripes 42.66 8.00e-79 287.00
IUUC-Tsy-119162 Tarsius syrichta 44.26 1.00e-40 159.00
IUUC-Tni-119793 Tetraodon nigroviridis 45.98 7.00e-44 171.00
IUUC-Tbe-127816 Tupaia belangeri 67.54 1.00e-84 306.00
IUUC-Ttr-129194 Tursiops truncatus 57.74 5.00e-132 464.00
IUUC-Vpa-130326 Vicugna pacos 63.45 5.00e-143 500.00
IUUC-Xtr-132216 Xenopus tropicalis 57.17 2.00e-128 452.00
Created Date 25-Jun-2017

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