• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Ago-007917
Ensembl Protein ID AAS51907
UniProt Accession Q75AD1; URM1_ASHGO
Genbank Protein ID AAS51907.1
Protein Name Ubiquitin-related modifier 1
Genbank Nucleotide ID AE016817
Gene Name URM1; ADL014W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AGOS_ADL014W AAS51907 AAS51907
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 71.00 1.00e-37 148.00 IUUC-Sce-106366
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Ashbya gossypii
Functional Description
(View)

Functional Description


     Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
 Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Protein Sequence
(Fasta)
MVQVQVEFLG GLDVIFSKQR KHQVSVEGAN GSVTVGDLID YIVSNMIQKQ KDVSVFLEDN 60
TIRPGILTLI NDTDWELEGE KEYVLEDGDI VSFTSTLHGG
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ago-007917|ULD,UBQ_Other|Ashbya gossypii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGTGCAGG TGCAAGTAGA ATTCCTTGGT GGCCTCGATG TCATATTTTC TAAGCAACGG 60
AAACATCAGG TTTCTGTAGA GGGAGCGAAC GGCTCAGTCA CGGTAGGTGA TCTCATAGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ago-007917|ULD,UBQ_Other|Ashbya gossypii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1185--Reference proteome
KW-0819--tRNA processing
KW-0833--Ubl conjugation pathway
Interpro

IPR012675--Beta-grasp_dom
IPR016155--Mopterin_synth/thiamin_S_b
IPR015221--Urm1
Pfam

PF09138--Urm1
Gene Ontology

GO:0005829--C:cytosol
GO:0031386--F:protein tag
GO:0016783--F:sulfurtransferase activity
GO:0007114--P:cell budding
GO:0034599--P:cellular response to oxidative stress
GO:0001403--P:invasive growth in response to glucose limitation
GO:0032447--P:protein urmylation
GO:0002143--P:tRNA wobble position uridine thiolation
KEGG ago:AGOS_ADL014W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002254 Ailuropoda melanoleuca 42.42 2.00e-20 88.20
IUUC-Atr-003089 Amborella trichopoda 40.59 2.00e-19 85.10
IUUC-Apl-003382 Anas platyrhynchos 41.94 3.00e-19 83.60
IUUC-Aca-004981 Anolis carolinensis 43.43 5.00e-20 86.70
IUUC-Aly-005517 Arabidopsis lyrata 39.78 2.00e-18 80.90
IUUC-Ath-006718 Arabidopsis thaliana 41.98 1.00e-16 75.90
IUUC-Acl-008054 Aspergillus clavatus 57.69 2.00e-14 67.80
IUUC-Afl-008704 Aspergillus flavus 45.56 6.00e-20 86.30
IUUC-Aor-009890 Aspergillus oryzae 47.06 9.00e-24 99.80
IUUC-Bta-012448 Bos taurus 42.42 3.00e-20 87.80
IUUC-Bci-013865 Botrytis cinerea 47.06 7.00e-23 96.30
IUUC-Bdi-014980 Brachypodium distachyon 43.04 5.00e-15 70.10
IUUC-Bol-016055 Brassica oleracea 41.67 2.00e-17 78.20
IUUC-Bra-016845 Brassica rapa 41.67 2.00e-17 78.20
IUUC-Cel-018485 Caenorhabditis elegans 32.35 4.00e-11 57.00
IUUC-Cja-019587 Callithrix jacchus 43.43 1.00e-20 89.00
IUUC-Cfa-020653 Canis familiaris 41.41 4.00e-20 87.40
IUUC-Cpo-021622 Cavia porcellus 43.43 1.00e-20 89.00
IUUC-Cre-023015 Chlamydomonas reinhardtii 46.53 5.00e-23 96.70
IUUC-Csa-023756 Chlorocebus sabaeus 35.42 7.00e-14 67.40
IUUC-Cho-025084 Choloepus hoffmanni 33.33 2.60e-01 26.90
IUUC-Cgl-026518 Colletotrichum gloeosporioides 44.12 4.00e-22 94.40
IUUC-Cne-026953 Cryptococcus neoformans 40.95 2.00e-17 79.30
IUUC-Cme-027314 Cyanidioschyzon merolae 44.00 3.00e-19 84.00
IUUC-Dre-027884 Danio rerio 41.24 4.00e-19 84.00
IUUC-Dno-029262 Dasypus novemcinctus 32.58 8.00e-12 60.80
IUUC-Dor-030601 Dipodomys ordii 45.45 3.00e-08 47.80
IUUC-Dme-031893 Drosophila melanogaster 38.38 4.00e-18 80.50
IUUC-Ete-032773 Echinops telfairi 44.21 7.00e-20 86.30
IUUC-Eca-034187 Equus caballus 42.42 2.00e-20 88.60
IUUC-Eeu-034808 Erinaceus europaeus 43.43 3.00e-21 90.90
IUUC-Fca-036107 Felis catus 41.41 4.00e-20 87.00
IUUC-Fal-036607 Ficedula albicollis 40.86 2.00e-18 81.60
IUUC-Fox-037698 Fusarium oxysporum 44.12 2.00e-22 95.10
IUUC-Gmo-039492 Gadus morhua 36.36 1.00e-16 75.90
IUUC-Ggr-039965 Gaeumannomyces graminis 46.94 2.00e-22 95.50
IUUC-Gga-041268 Gallus gallus 43.43 8.00e-21 89.40
IUUC-Gac-042111 Gasterosteus aculeatus 40.40 5.00e-19 83.60
IUUC-Gma-043240 Glycine max 41.67 1.00e-16 75.90
IUUC-Ggo-045176 Gorilla gorilla 36.84 3.00e-09 52.00
IUUC-Hsa-046077 Homo sapiens 42.42 3.00e-16 74.70
IUUC-Itr-048111 Ictidomys tridecemlineatus 43.96 3.00e-15 70.50
IUUC-Kpa-049157 Komagataella pastoris 56.44 4.00e-28 113.00
IUUC-Lch-049889 Latimeria chalumnae 42.42 5.00e-20 86.70
IUUC-Lpe-050783 Leersia perrieri 41.46 2.00e-14 68.20
IUUC-Loc-052400 Lepisosteus oculatus 38.38 3.00e-18 80.90
IUUC-Lma-053259 Leptosphaeria maculans 38.24 4.00e-19 84.00
IUUC-Laf-053596 Loxodonta africana 42.57 8.00e-20 86.30
IUUC-Mcc-054845 Macaca mulatta 42.22 5.00e-18 80.10
IUUC-Meu-055968 Macropus eugenii 43.43 5.00e-21 90.10
IUUC-Mor-057126 Magnaporthe oryzae 44.66 1.00e-19 86.70
IUUC-Mpo-057311 Magnaporthe poae 44.12 3.00e-22 95.10
IUUC-Mtr-058266 Medicago truncatula 38.37 6.00e-15 70.10
IUUC-Mla-058847 Melampsora laricipopulina 34.62 7.00e-11 57.00
IUUC-Mga-059468 Meleagris gallopavo 41.94 5.00e-19 83.20
IUUC-Mvi-060235 Microbotryum violaceum 52.38 9.00e-14 67.00
IUUC-Mdo-061948 Monodelphis domestica 44.44 2.00e-21 91.70
IUUC-Mmu-063946 Mus musculus 43.30 2.00e-20 88.60
IUUC-Mac-064812 Musa acuminata 43.21 2.00e-14 68.20
IUUC-Mpu-066763 Mustela putorius furo 43.43 3.00e-21 90.90
IUUC-Mlu-066970 Myotis lucifugus 38.16 1.00e-13 65.10
IUUC-Ncr-068824 Neurospora crassa 43.69 2.00e-21 91.70
IUUC-Nle-069849 Nomascus leucogenys 36.84 5.00e-13 64.70
IUUC-Opr-070227 Ochotona princeps 43.43 1.00e-20 89.00
IUUC-Ont-072530 Oreochromis niloticus 39.39 8.00e-19 82.80
IUUC-Oan-073191 Ornithorhynchus anatinus 40.66 3.00e-17 77.40
IUUC-Ocu-074460 Oryctolagus cuniculus 41.41 4.00e-20 87.00
IUUC-Oba-075499 Oryza barthii 41.98 2.00e-14 69.30
IUUC-Obr-076896 Oryza brachyantha 44.44 4.00e-15 72.40
IUUC-Ogl-077834 Oryza glaberrima 41.98 2.00e-14 68.60
IUUC-Ogu-078622 Oryza glumaepatula 41.98 2.00e-14 68.60
IUUC-Oin-079358 Oryza indica 41.98 4.00e-14 68.90
IUUC-Olo-081035 Oryza longistaminata 41.41 5.00e-17 78.20
IUUC-Oni-082425 Oryza nivara 41.98 2.00e-14 68.60
IUUC-Opu-083461 Oryza punctata 42.50 7.00e-14 67.40
IUUC-Oru-084875 Oryza rufipogon 45.59 1.00e-12 61.60
IUUC-Oga-089128 Otolemur garnettii 42.42 1.00e-20 89.00
IUUC-Oar-089896 Ovis aries 42.42 3.00e-20 87.80
IUUC-Ptr-091618 Pan troglodytes 36.84 3.00e-09 52.00
IUUC-Pan-092238 Papio anubis 38.16 2.00e-13 66.20
IUUC-Psi-093879 Pelodiscus sinensis 43.16 1.00e-19 85.10
IUUC-Pma-094484 Petromyzon marinus 43.21 4.00e-15 70.50
IUUC-Ppa-095801 Physcomitrella patens 45.24 9.00e-17 75.90
IUUC-Pfo-097192 Poecilia formosa 40.40 3.00e-18 80.90
IUUC-Pab-098203 Pongo abelii 42.42 5.00e-16 73.60
IUUC-Pop-099614 Populus trichocarpa 41.98 7.00e-16 73.20
IUUC-Pca-100507 Procavia capensis 36.84 2.00e-13 64.70
IUUC-Ppe-101174 Prunus persica 41.58 1.00e-20 88.60
IUUC-Pva-102735 Pteropus vampyrus 43.43 2.00e-17 77.80
IUUC-Pgr-103510 Puccinia graminis 36.19 1.00e-13 66.20
IUUC-Ptt-103918 Puccinia triticina 40.00 1.00e-14 69.70
IUUC-Pte-104173 Pyrenophora teres 42.16 2.00e-20 88.60
IUUC-Pyt-104806 Pyrenophora triticirepentis 42.16 2.00e-20 88.20
IUUC-Rno-105820 Rattus norvegicus 43.30 1.00e-20 89.00
IUUC-Sce-106366 Saccharomyces cerevisiae 71.00 1.00e-38 148.00
IUUC-Sja-107727 Schizosaccharomyces japonicus 44.33 3.00e-20 88.20
IUUC-Spo-108074 Schizosaccharomyces pombe 47.47 1.00e-16 75.50
IUUC-Smo-108944 Selaginella moellendorffii 40.66 2.00e-16 74.70
IUUC-Sit-110277 Setaria italica 39.29 1.00e-14 68.60
IUUC-Sly-111505 Solanum lycopersicum 40.96 4.00e-16 73.90
IUUC-Stu-112076 Solanum tuberosum 40.96 4.00e-16 73.90
IUUC-Sar-113350 Sorex araneus 38.24 1.10e+00 26.60
IUUC-Sbi-114274 Sorghum bicolor 42.65 4.00e-13 63.90
IUUC-Sre-114953 Sporisorium reilianum 45.19 6.00e-21 90.10
IUUC-Ssc-115418 Sus scrofa 43.43 8.00e-21 89.40
IUUC-Tgu-117311 Taeniopygia guttata 41.94 9.00e-19 82.40
IUUC-Tru-118598 Takifugu rubripes 41.76 1.00e-17 79.00
IUUC-Tni-120109 Tetraodon nigroviridis 42.00 5.00e-18 80.10
IUUC-Tca-120942 Theobroma cacao 37.04 4.00e-14 67.00
IUUC-Tre-122099 Trichoderma reesei 43.62 3.00e-13 63.90
IUUC-Tvi-122285 Trichoderma virens 44.12 1.00e-15 72.80
IUUC-Tae-125193 Triticum aestivum 43.21 6.00e-16 73.20
IUUC-Tur-126677 Triticum urartu 38.71 2.00e-13 65.10
IUUC-Tme-127120 Tuber melanosporum 47.57 3.00e-24 101.00
IUUC-Tbe-128050 Tupaia belangeri 39.39 2.00e-13 65.50
IUUC-Ttr-129019 Tursiops truncatus 42.42 5.00e-19 83.60
IUUC-Uma-129483 Ustilago maydis 43.27 2.00e-19 85.10
IUUC-Vda-129690 Verticillium dahliae 36.61 8.00e-16 73.20
IUUC-Vvi-131174 Vitis vinifera 39.51 1.00e-15 72.00
IUUC-Xma-133862 Xiphophorus maculatus 40.40 3.00e-18 80.90
IUUC-Yli-134398 Yarrowia lipolytica 43.14 9.00e-21 89.40
IUUC-Zma-134964 Zea mays 42.68 2.00e-14 68.60
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved