iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cin-025597

Ensembl Protein ID

ENSCINP00000007786.3

UniProt Accession

F6TIU3; F6TIU3_CIOIN

Genbank Protein ID

ENSCINP00000007786

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

EAAA01002543

Gene Name

LOC100177148

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000003743.3	ENSCINT00000007786.3	ENSCINP00000007786.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.40e-20	70.3	50	86

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvl 35
           gH + v+++  ++ d t +++G+ D ++k+WD  tg++
   Q: 50   GHRGTVWSVdvNW-DsTKVLTGAADLSCKLWDCETGKV 86
           8*******63377.55*****************99986 PP

Organism

Ciona intestinalis

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPLMLQGHE RAITQIRYNR EGDLLFTVAK DATPNVWYTI NGERLGTYDG HRGTVWSVDV 60
NWDSTKVLTG AADLSCKLWD CETGKVINTW DTKSSVRSSN FSYCGNMINF TTDRQMKHEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTTAAAAA TAAATTTAAG TGGAGATCGG AAATGGCGAC CGTCACAACC TTGTTTGCAA 60
ATACTTTTGG TTTGTCACGG TTGACTGATA TTTAGTTATT TCATCGTTGG GGAATTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	56.64	8.00e-34	136.00
IUUC-Aml-001321	Ailuropoda melanoleuca	59.57	3.00e-117	413.00
IUUC-Atr-002468	Amborella trichopoda	52.87	1.00e-51	194.00
IUUC-Apl-003841	Anas platyrhynchos	60.19	3.00e-119	419.00
IUUC-Aca-005123	Anolis carolinensis	59.57	5.00e-119	419.00
IUUC-Aly-006532	Arabidopsis lyrata	46.34	1.00e-82	298.00
IUUC-Ath-007094	Arabidopsis thaliana	45.73	8.00e-84	302.00
IUUC-Ago-008000	Ashbya gossypii	43.98	4.00e-88	316.00
IUUC-Acl-008098	Aspergillus clavatus	47.18	6.00e-93	332.00
IUUC-Afl-008494	Aspergillus flavus	48.49	5.00e-96	342.00
IUUC-Afu-009080	Aspergillus fumigatus	46.88	1.00e-92	331.00
IUUC-Ani-009230	Aspergillus nidulans	47.45	2.00e-92	331.00
IUUC-Aor-010114	Aspergillus oryzae	48.49	5.00e-96	342.00
IUUC-Ate-010285	Aspergillus terreus	47.59	4.00e-94	336.00
IUUC-Ame-011534	Astyanax mexicanus	57.58	9.00e-116	408.00
IUUC-Bgr-012121	Blumeria graminis	46.50	2.00e-89	320.00
IUUC-Bta-013143	Bos taurus	59.69	7.00e-118	415.00
IUUC-Bci-013950	Botrytis cinerea	49.85	3.00e-97	346.00
IUUC-Bdi-015019	Brachypodium distachyon	47.85	6.00e-88	316.00
IUUC-Bol-015709	Brassica oleracea	45.45	1.00e-81	296.00
IUUC-Bra-017760	Brassica rapa	45.45	4.00e-82	297.00
IUUC-Cel-018226	Caenorhabditis elegans	45.57	2.00e-89	320.00
IUUC-Cja-019741	Callithrix jacchus	59.76	4.00e-118	416.00
IUUC-Cfa-021204	Canis familiaris	59.63	3.00e-117	413.00
IUUC-Cpo-021661	Cavia porcellus	59.88	1.00e-117	414.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	46.30	2.00e-88	317.00
IUUC-Csa-024038	Chlorocebus sabaeus	59.76	4.00e-118	416.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	47.89	2.00e-91	327.00
IUUC-Cne-026838	Cryptococcus neoformans	48.93	7.00e-92	328.00
IUUC-Cme-027304	Cyanidioschyzon merolae	44.00	2.00e-77	280.00
IUUC-Dre-028567	Danio rerio	58.77	3.00e-118	416.00
IUUC-Dno-029171	Dasypus novemcinctus	59.57	2.00e-117	414.00
IUUC-Dor-030257	Dipodomys ordii	42.46	5.00e-39	153.00
IUUC-Dse-031191	Dothistroma septosporum	47.27	2.00e-94	337.00
IUUC-Dme-031879	Drosophila melanogaster	61.09	3.00e-121	426.00
IUUC-Ete-032336	Echinops telfairi	51.87	9.00e-63	231.00
IUUC-Eca-033259	Equus caballus	59.63	3.00e-117	413.00
IUUC-Eeu-035153	Erinaceus europaeus	50.68	2.00e-37	147.00
IUUC-Fca-036489	Felis catus	59.63	3.00e-117	413.00
IUUC-Fal-037485	Ficedula albicollis	60.49	1.00e-119	421.00
IUUC-Fox-037860	Fusarium oxysporum	48.65	5.00e-93	332.00
IUUC-Fso-038188	Fusarium solani	47.45	7.00e-89	318.00
IUUC-Gmo-039311	Gadus morhua	58.33	2.00e-117	413.00
IUUC-Ggr-040045	Gaeumannomyces graminis	49.70	1.00e-96	345.00
IUUC-Gga-040645	Gallus gallus	58.86	9.00e-118	414.00
IUUC-Gac-042086	Gasterosteus aculeatus	58.23	7.00e-116	408.00
IUUC-Gma-043930	Glycine max	44.79	1.00e-84	304.00
IUUC-Ggo-045578	Gorilla gorilla	59.76	4.00e-118	416.00
IUUC-Hsa-046734	Homo sapiens	59.76	4.00e-118	416.00
IUUC-Hvu-047553	Hordeum vulgare	47.24	1.00e-86	311.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	59.33	5.00e-117	412.00
IUUC-Kpa-049325	Komagataella pastoris	43.77	9.00e-91	325.00
IUUC-Lch-049620	Latimeria chalumnae	59.73	1.00e-107	381.00
IUUC-Lpe-051338	Leersia perrieri	46.62	3.00e-83	300.00
IUUC-Loc-052094	Lepisosteus oculatus	55.86	2.00e-106	377.00
IUUC-Lma-053047	Leptosphaeria maculans	48.95	1.00e-95	341.00
IUUC-Laf-053801	Loxodonta africana	59.75	2.00e-114	404.00
IUUC-Mcc-055498	Macaca mulatta	52.74	3.00e-93	333.00
IUUC-Meu-056729	Macropus eugenii	54.10	3.00e-104	370.00
IUUC-Mor-057025	Magnaporthe oryzae	49.40	2.00e-96	343.00
IUUC-Mpo-057511	Magnaporthe poae	50.30	7.00e-97	345.00
IUUC-Mtr-058051	Medicago truncatula	46.18	1.00e-84	305.00
IUUC-Mla-059061	Melampsora laricipopulina	46.30	4.00e-89	319.00
IUUC-Mga-059229	Meleagris gallopavo	59.51	8.00e-117	411.00
IUUC-Mvi-060399	Microbotryum violaceum	44.14	5.00e-82	296.00
IUUC-Mmr-060764	Microcebus murinus	59.69	3.00e-118	416.00
IUUC-Mdo-062088	Monodelphis domestica	59.33	8.00e-118	415.00
IUUC-Mmu-064304	Mus musculus	59.69	6.00e-118	415.00
IUUC-Mac-065520	Musa acuminata	46.42	3.00e-84	303.00
IUUC-Mpu-066340	Mustela putorius furo	59.63	3.00e-117	413.00
IUUC-Mlu-067111	Myotis lucifugus	59.57	9.00e-118	414.00
IUUC-Nfi-068478	Neosartorya fischeri	46.88	1.00e-92	331.00
IUUC-Ncr-068820	Neurospora crassa	48.49	5.00e-94	336.00
IUUC-Nle-069903	Nomascus leucogenys	59.63	1.00e-117	414.00
IUUC-Opr-070221	Ochotona princeps	58.46	7.00e-115	405.00
IUUC-Ont-071765	Oreochromis niloticus	58.46	1.00e-117	414.00
IUUC-Oan-073660	Ornithorhynchus anatinus	57.19	3.00e-101	359.00
IUUC-Ocu-074039	Oryctolagus cuniculus	59.63	2.00e-117	414.00
IUUC-Oba-075395	Oryza barthii	42.94	9.00e-75	271.00
IUUC-Obr-076334	Oryza brachyantha	45.09	2.00e-82	297.00
IUUC-Ogl-077751	Oryza glaberrima	48.16	6.00e-91	325.00
IUUC-Ogu-078207	Oryza glumaepatula	47.69	9.00e-90	322.00
IUUC-Oin-079878	Oryza indica	47.55	2.00e-89	320.00
IUUC-Olo-080677	Oryza longistaminata	41.32	6.00e-82	296.00
IUUC-Ome-081228	Oryza meridionalis	34.68	6.00e-41	159.00
IUUC-Oni-082411	Oryza nivara	42.81	5.00e-73	266.00
IUUC-Opu-083136	Oryza punctata	48.16	8.00e-91	325.00
IUUC-Oru-084916	Oryza rufipogon	45.97	2.00e-87	314.00
IUUC-Osa-085776	Oryza sativa	48.16	6.00e-91	325.00
IUUC-Ola-087053	Oryzias latipes	59.15	4.00e-119	419.00
IUUC-Olu-087602	Ostreococcus lucimarinus	48.15	5.00e-89	319.00
IUUC-Oga-088154	Otolemur garnettii	59.63	1.00e-117	414.00
IUUC-Oar-089915	Ovis aries	59.57	3.00e-117	412.00
IUUC-Ptr-091124	Pan troglodytes	48.29	2.00e-85	307.00
IUUC-Pan-092035	Papio anubis	59.76	4.00e-118	416.00
IUUC-Psi-094096	Pelodiscus sinensis	55.76	1.00e-71	260.00
IUUC-Pno-094988	Phaeosphaeria nodorum	43.94	2.00e-83	301.00
IUUC-Ppa-095536	Physcomitrella patens	49.70	2.00e-91	327.00
IUUC-Pfo-096101	Poecilia formosa	58.77	4.00e-118	416.00
IUUC-Pab-097726	Pongo abelii	59.76	4.00e-118	416.00
IUUC-Pop-099617	Populus trichocarpa	45.40	9.00e-83	298.00
IUUC-Pca-101014	Procavia capensis	59.69	4.00e-118	416.00
IUUC-Ppe-101320	Prunus persica	45.09	1.00e-82	298.00
IUUC-Pva-102789	Pteropus vampyrus	56.13	8.00e-108	381.00
IUUC-Pgr-103479	Puccinia graminis	44.24	3.00e-87	313.00
IUUC-Ptt-103981	Puccinia triticina	44.24	3.00e-87	313.00
IUUC-Pte-104278	Pyrenophora teres	49.25	3.00e-93	333.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	49.25	3.00e-93	333.00
IUUC-Rno-105867	Rattus norvegicus	53.78	1.00e-99	355.00
IUUC-Sce-106251	Saccharomyces cerevisiae	45.48	4.00e-92	329.00
IUUC-Sha-107039	Sarcophilus harrisii	59.02	1.00e-117	414.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	47.27	2.00e-92	330.00
IUUC-Spo-108314	Schizosaccharomyces pombe	47.58	7.00e-92	328.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	49.55	1.00e-96	344.00
IUUC-Smo-108728	Selaginella moellendorffii	46.93	1.00e-86	311.00
IUUC-Sit-110801	Setaria italica	47.85	4.00e-89	320.00
IUUC-Sly-111326	Solanum lycopersicum	45.71	3.00e-84	303.00
IUUC-Stu-112458	Solanum tuberosum	45.71	3.00e-84	303.00
IUUC-Sbi-114063	Sorghum bicolor	47.24	2.00e-87	314.00
IUUC-Sre-115096	Sporisorium reilianum	43.28	3.00e-79	286.00
IUUC-Ssc-116080	Sus scrofa	59.69	6.00e-118	415.00
IUUC-Tgu-116988	Taeniopygia guttata	60.49	1.00e-119	421.00
IUUC-Tru-118766	Takifugu rubripes	57.93	5.00e-117	412.00
IUUC-Tni-120197	Tetraodon nigroviridis	57.93	2.00e-117	413.00
IUUC-Tca-121316	Theobroma cacao	45.71	1.00e-85	308.00
IUUC-Tre-122097	Trichoderma reesei	48.05	2.00e-90	324.00
IUUC-Tvi-122442	Trichoderma virens	48.05	1.00e-90	324.00
IUUC-Tae-125800	Triticum aestivum	46.93	7.00e-86	309.00
IUUC-Tur-126334	Triticum urartu	40.00	8.00e-66	242.00
IUUC-Tme-127038	Tuber melanosporum	48.80	5.00e-97	346.00
IUUC-Ttr-128659	Tursiops truncatus	56.10	1.00e-98	351.00
IUUC-Uma-129464	Ustilago maydis	43.58	1.00e-78	285.00
IUUC-Vda-129841	Verticillium dahliae	49.40	4.00e-94	336.00
IUUC-Vvi-131076	Vitis vinifera	46.18	1.00e-84	305.00
IUUC-Xtr-132395	Xenopus tropicalis	60.00	8.00e-120	421.00
IUUC-Xma-133383	Xiphophorus maculatus	58.77	7.00e-118	415.00
IUUC-Yli-134586	Yarrowia lipolytica	46.83	2.00e-82	297.00
IUUC-Zma-135904	Zea mays	47.85	2.00e-88	317.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence