iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121316

Ensembl Protein ID

EOY34328

UniProt Accession

A0A061GY31; A0A061GY31_THECC

Genbank Protein ID

EOY34327.1; EOY34328.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

CM001887; CM001887

Gene Name

TCM_042036

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_042036	EOY34328	EOY34328

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-26	91.7	50	87
UBD/Beta-Prp	2.70e-41	142.6	7	251

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v++++   d t+l++Gs D t k+W++ tg++l
   Q: 50   GHNGAVWSCDVsRDsTRLITGSADQTAKLWNVQTGTQL 87
           8***********777*******************9986 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
           + h+ ++t +k+ +d++ll++  +d+t +vw +++g  l ++ gh+++v++++ s+d+  l+tgs D+t+k+w+++tg+++ t++  ++ ++s++f   gd
   Q: 7    KGHERPLTFLKYNRDGDLLFSCAKDHTPTVWFADNGERLGTYRGHNGAVWSCDVSRDSTRLITGSADQTAKLWNVQTGTQLFTFN-FDSPARSVDFAI-GD 105
           4455566666666666666666666666666666666666666666666666666666666666666666666666666666666.666666666665.66 PP
   S: 108  klvsGshdrtirvwdletgqclee.....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvys 185
           kl++ + d   ++          +                     + +g +g +n + + p ++ ++s++ D ++r+Wd++tgkllr+   ++gh+++++s
   Q: 106  KLAVITTDPFMEL----------TsaihvkritrdateqtgesvlVIKGPQGRINRAIWGPLNSTIISAGEDAVIRIWDSETGKLLREAdkESGHKKPITS 196
           6655555666655..........044444444445778889999999********************************************777******* PP
   S: 186  lsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs 241
           l+ + +g ++++gsld++ klwd++t + ++t+    ++v+ v++sp  +++v g+
   Q: 197  LAKSADGSHFLTGSLDKSAKLWDVRTLTLIKTYVTE-RPVNAVALSPLLDHVVLGG 251
           ********************************9865.5788888876666655555 PP

Organism

Theobroma cacao

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLKYNR DGDLLFSCAK DHTPTVWFAD NGERLGTYRG HNGAVWSCDV 60
SRDSTRLITG SADQTAKLWN VQTGTQLFTF NFDSPARSVD FAIGDKLAVI TTDPFMELTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAGAATCT ACAGAAGTAA GCAGCTACCG CAAAACCCTA ATTCTAAGTA GTGTGAAGAA 60
ACAAAAGCTT GGCGATTTTT TCTTGTTATT TGCGAGGAAC AAGAGACAAG ATGAGGCCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	44.84	8.00e-57	213.00
IUUC-Aml-001321	Ailuropoda melanoleuca	46.46	3.00e-85	307.00
IUUC-Atr-002468	Amborella trichopoda	73.75	2.00e-100	357.00
IUUC-Apl-003841	Anas platyrhynchos	46.77	1.00e-86	311.00
IUUC-Aca-005123	Anolis carolinensis	46.63	4.00e-88	317.00
IUUC-Aly-005473	Arabidopsis lyrata	82.32	9.00e-163	565.00
IUUC-Ath-007094	Arabidopsis thaliana	80.49	3.00e-161	560.00
IUUC-Ago-008000	Ashbya gossypii	45.21	5.00e-77	280.00
IUUC-Acl-008098	Aspergillus clavatus	44.71	5.00e-77	280.00
IUUC-Afl-008494	Aspergillus flavus	45.85	9.00e-81	292.00
IUUC-Afu-009080	Aspergillus fumigatus	44.41	3.00e-77	281.00
IUUC-Ani-009230	Aspergillus nidulans	46.48	2.00e-80	291.00
IUUC-Aor-010114	Aspergillus oryzae	45.85	9.00e-81	292.00
IUUC-Ate-010285	Aspergillus terreus	45.57	3.00e-79	287.00
IUUC-Ame-011534	Astyanax mexicanus	45.59	1.00e-87	315.00
IUUC-Bgr-012121	Blumeria graminis	43.21	3.00e-74	271.00
IUUC-Bta-013143	Bos taurus	46.63	6.00e-86	309.00
IUUC-Bci-013950	Botrytis cinerea	45.23	9.00e-81	292.00
IUUC-Bdi-015019	Brachypodium distachyon	82.21	2.00e-160	557.00
IUUC-Bol-015709	Brassica oleracea	82.73	2.00e-165	575.00
IUUC-Bra-017760	Brassica rapa	82.73	1.00e-166	578.00
IUUC-Cel-018226	Caenorhabditis elegans	41.69	3.00e-73	268.00
IUUC-Cja-019741	Callithrix jacchus	46.63	5.00e-86	310.00
IUUC-Cfa-021204	Canis familiaris	46.46	3.00e-85	307.00
IUUC-Cpo-021661	Cavia porcellus	46.15	5.00e-85	306.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	51.84	2.00e-102	364.00
IUUC-Csa-024038	Chlorocebus sabaeus	46.63	5.00e-86	310.00
IUUC-Cin-025597	Ciona intestinalis	45.71	2.00e-85	308.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	44.95	1.00e-77	282.00
IUUC-Cne-026838	Cryptococcus neoformans	42.25	6.00e-77	280.00
IUUC-Cme-027304	Cyanidioschyzon merolae	54.63	6.00e-92	329.00
IUUC-Dre-028567	Danio rerio	45.40	4.00e-88	317.00
IUUC-Dno-029171	Dasypus novemcinctus	46.46	2.00e-84	305.00
IUUC-Dor-030257	Dipodomys ordii	32.95	3.00e-26	111.00
IUUC-Dse-031191	Dothistroma septosporum	44.38	4.00e-77	280.00
IUUC-Dme-031879	Drosophila melanogaster	48.62	2.00e-89	321.00
IUUC-Ete-032336	Echinops telfairi	39.35	4.00e-41	159.00
IUUC-Eca-033259	Equus caballus	46.46	4.00e-85	306.00
IUUC-Eeu-035153	Erinaceus europaeus	45.26	6.00e-27	114.00
IUUC-Fca-036489	Felis catus	46.46	4.00e-85	306.00
IUUC-Fal-037485	Ficedula albicollis	46.32	2.00e-86	311.00
IUUC-Fox-037860	Fusarium oxysporum	46.18	2.00e-79	288.00
IUUC-Fso-038188	Fusarium solani	46.48	4.00e-80	290.00
IUUC-Gmo-039311	Gadus morhua	44.62	1.00e-85	309.00
IUUC-Ggr-040045	Gaeumannomyces graminis	45.37	4.00e-78	283.00
IUUC-Gga-040645	Gallus gallus	45.81	3.00e-85	307.00
IUUC-Gac-042086	Gasterosteus aculeatus	45.71	7.00e-86	309.00
IUUC-Gma-043246	Glycine max	94.17	0.00e+00	639.00
IUUC-Ggo-045578	Gorilla gorilla	46.63	5.00e-86	310.00
IUUC-Hsa-046734	Homo sapiens	46.63	5.00e-86	310.00
IUUC-Hvu-047553	Hordeum vulgare	82.21	2.00e-160	557.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	46.46	5.00e-85	306.00
IUUC-Kpa-049325	Komagataella pastoris	46.79	9.00e-81	292.00
IUUC-Lch-049620	Latimeria chalumnae	45.85	8.00e-78	282.00
IUUC-Lpe-051338	Leersia perrieri	80.06	4.00e-150	523.00
IUUC-Loc-052094	Lepisosteus oculatus	40.92	2.00e-72	265.00
IUUC-Lma-053047	Leptosphaeria maculans	47.38	2.00e-82	298.00
IUUC-Laf-053801	Loxodonta africana	46.39	1.00e-82	298.00
IUUC-Mcc-055498	Macaca mulatta	41.72	2.00e-67	248.00
IUUC-Meu-056729	Macropus eugenii	43.12	3.00e-76	277.00
IUUC-Mor-057025	Magnaporthe oryzae	45.23	2.00e-76	278.00
IUUC-Mpo-057511	Magnaporthe poae	46.15	1.00e-77	282.00
IUUC-Mtr-058051	Medicago truncatula	91.72	0.00e+00	628.00
IUUC-Mla-059061	Melampsora laricipopulina	45.09	7.00e-80	289.00
IUUC-Mga-059229	Meleagris gallopavo	46.18	4.00e-84	303.00
IUUC-Mvi-060399	Microbotryum violaceum	44.94	8.00e-79	286.00
IUUC-Mmr-060764	Microcebus murinus	46.63	2.00e-86	311.00
IUUC-Mdo-062088	Monodelphis domestica	46.01	5.00e-85	306.00
IUUC-Mmu-064304	Mus musculus	46.32	6.00e-86	309.00
IUUC-Mac-065520	Musa acuminata	85.67	2.00e-169	587.00
IUUC-Mpu-066340	Mustela putorius furo	46.46	4.00e-85	306.00
IUUC-Mlu-067111	Myotis lucifugus	46.32	2.00e-85	307.00
IUUC-Nfi-068478	Neosartorya fischeri	44.41	9.00e-78	282.00
IUUC-Ncr-068820	Neurospora crassa	46.77	4.00e-79	286.00
IUUC-Nle-069903	Nomascus leucogenys	46.46	2.00e-85	308.00
IUUC-Opr-070221	Ochotona princeps	45.40	2.00e-83	301.00
IUUC-Ont-071765	Oreochromis niloticus	46.32	3.00e-89	321.00
IUUC-Oan-073660	Ornithorhynchus anatinus	45.21	9.00e-73	265.00
IUUC-Ocu-074039	Oryctolagus cuniculus	46.46	3.00e-85	307.00
IUUC-Oba-075395	Oryza barthii	76.69	6.00e-146	508.00
IUUC-Obr-076334	Oryza brachyantha	78.53	7.00e-152	528.00
IUUC-Ogl-077751	Oryza glaberrima	83.44	1.00e-163	567.00
IUUC-Ogu-078207	Oryza glumaepatula	82.15	8.00e-160	555.00
IUUC-Oin-079878	Oryza indica	82.82	2.00e-161	560.00
IUUC-Olo-080677	Oryza longistaminata	68.16	4.00e-146	509.00
IUUC-Ome-081228	Oryza meridionalis	64.58	2.00e-83	301.00
IUUC-Oni-082411	Oryza nivara	75.46	3.00e-141	493.00
IUUC-Opu-083136	Oryza punctata	83.13	4.00e-163	566.00
IUUC-Oru-084916	Oryza rufipogon	80.60	9.00e-160	555.00
IUUC-Osa-085776	Oryza sativa	83.44	1.00e-163	567.00
IUUC-Ola-087053	Oryzias latipes	46.01	5.00e-87	313.00
IUUC-Olu-087602	Ostreococcus lucimarinus	62.46	9.00e-124	435.00
IUUC-Oga-088154	Otolemur garnettii	46.15	2.00e-84	304.00
IUUC-Oar-089915	Ovis aries	46.46	3.00e-85	307.00
IUUC-Ptr-091124	Pan troglodytes	38.27	3.00e-58	218.00
IUUC-Pan-092035	Papio anubis	46.63	5.00e-86	310.00
IUUC-Psi-094096	Pelodiscus sinensis	48.24	2.00e-52	197.00
IUUC-Pno-094988	Phaeosphaeria nodorum	44.92	4.00e-73	267.00
IUUC-Ppa-095536	Physcomitrella patens	77.61	7.00e-156	542.00
IUUC-Pfo-096101	Poecilia formosa	45.40	5.00e-88	316.00
IUUC-Pab-097726	Pongo abelii	46.63	5.00e-86	310.00
IUUC-Pop-099617	Populus trichocarpa	86.81	7.00e-174	602.00
IUUC-Pca-101014	Procavia capensis	46.63	4.00e-86	310.00
IUUC-Ppe-101320	Prunus persica	90.80	0.00e+00	625.00
IUUC-Pva-102789	Pteropus vampyrus	42.94	2.00e-73	268.00
IUUC-Pgr-103479	Puccinia graminis	45.40	6.00e-80	290.00
IUUC-Ptt-103981	Puccinia triticina	45.40	2.00e-80	291.00
IUUC-Pte-104278	Pyrenophora teres	46.15	8.00e-80	289.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	46.15	8.00e-80	289.00
IUUC-Rno-105867	Rattus norvegicus	44.51	5.00e-70	256.00
IUUC-Sce-106251	Saccharomyces cerevisiae	41.62	1.00e-72	265.00
IUUC-Sha-107039	Sarcophilus harrisii	45.87	4.00e-85	307.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	45.87	5.00e-83	300.00
IUUC-Spo-108314	Schizosaccharomyces pombe	45.40	6.00e-85	306.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	45.23	1.00e-80	292.00
IUUC-Smo-108728	Selaginella moellendorffii	76.31	1.00e-152	531.00
IUUC-Sit-110801	Setaria italica	81.90	1.00e-160	557.00
IUUC-Sly-111326	Solanum lycopersicum	87.42	1.00e-174	604.00
IUUC-Stu-112458	Solanum tuberosum	89.26	1.00e-176	611.00
IUUC-Sbi-114063	Sorghum bicolor	80.67	1.00e-158	551.00
IUUC-Sre-115096	Sporisorium reilianum	44.51	4.00e-74	270.00
IUUC-Ssc-116080	Sus scrofa	46.63	6.00e-86	310.00
IUUC-Tgu-116988	Taeniopygia guttata	46.46	2.00e-86	311.00
IUUC-Tru-118766	Takifugu rubripes	45.09	2.00e-87	314.00
IUUC-Tni-120197	Tetraodon nigroviridis	45.40	7.00e-88	316.00
IUUC-Tre-122097	Trichoderma reesei	47.71	3.00e-81	294.00
IUUC-Tvi-122442	Trichoderma virens	47.09	3.00e-80	290.00
IUUC-Tae-125542	Triticum aestivum	82.01	3.00e-160	556.00
IUUC-Tur-126334	Triticum urartu	73.01	2.00e-135	474.00
IUUC-Tme-127038	Tuber melanosporum	47.69	4.00e-85	306.00
IUUC-Ttr-128659	Tursiops truncatus	43.56	9.00e-67	246.00
IUUC-Uma-129464	Ustilago maydis	44.21	2.00e-74	271.00
IUUC-Vda-129841	Verticillium dahliae	47.08	4.00e-80	290.00
IUUC-Vvi-131076	Vitis vinifera	90.49	0.00e+00	628.00
IUUC-Xtr-132395	Xenopus tropicalis	47.40	4.00e-88	317.00
IUUC-Xma-133383	Xiphophorus maculatus	45.40	8.00e-88	316.00
IUUC-Yli-134586	Yarrowia lipolytica	45.43	3.00e-73	267.00
IUUC-Zma-135667	Zea mays	80.98	1.00e-159	554.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence